Clinical Trials on Neurologic Abnormalities

Total 72771 results

St. Jude Children's Research Hospital

Completed

Neurocognitive and Psychosocial Outcomes in Survivors of Childhood Leukemia With Down Syndrome

Leukemia | Down Syndrome

United States
National Taiwan University Hospital

Completed

Role of Sleep Apnea in the Neuropsychological Function in Down Syndrome People

Down Syndrome
Universidad Autonoma de San Luis Potosí

Unknown

Fluor Varnish With Silver Nanoparticles for Dental Remineralization in Patients With Trisomy 21

Down Syndrome

Mexico
Mayo Clinic
Novartis; National Center for Research Resources (NCRR)

Completed

Octreotide in Severe Polycystic Liver Disease

Liver Diseases | Abdominal Pain | Polycystic Kidney, Autosomal Dominant | Hepatomegaly | Polycystic Liver Disease | Kidney, Polycystic

United States
BERTHILLIER Julien

Completed

Side Pole Static Ankle Foot Orthosis in Children With Neurological Disorders (SPS-AFO)

Neurological Disorder
Carelon Research
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Completed

Congenital Heart Disease: Impact on Learning and Development in Down Syndrome (CHILD-DS) (CHILD-DS)

Down Syndrome | Congenital Heart Disease

United States, Canada
University Children's Hospital, Zurich
University of Lausanne Hospitals; University of Bern; University of Geneva, Switzerland

Recruiting

The Swiss Neurodevelopmental Outcome Registry for Children With CHD (SwissORCHID)

Congenital Heart Disease | Cardiac Disease | Neurodevelopmental Abnormality | Intensive Care Neurological Disorder

Switzerland
Meir Medical Center

Terminated

Influence of Medical Clowning in Videofluoroscopic Examination of Pediatric Speech Disorder

Velopharyngeal Insufficiency
Postgraduate Institute of Medical Education and...

Completed

Effect Of Combination of Morphine+Fentanyl on Emergence Delirium in Patients of Cleft Lip and Palate Repair

Anesthesia Emergence Delirium

India
Eunice Kennedy Shriver National Institute of Child...

Completed

Characterization of WAGR Syndrome and Other Chromosome 11 Gene Deletions

Urogenital Abnormalities | Mental Retardation | Wilm's Tumor | WAGR Syndrome | Aniridia

United States
Zayed Military Hospital

Recruiting

Comparison of CHOKAI vs STONE Score to Predict the Presence of Ureteric Stones in Patients With Renal Colic: A Multi-center Prospective Observational Study

Ureteric Stone

United Arab Emirates
University of Texas Southwestern Medical Center

Not yet recruiting

Transcutaneous Tibial Nerve Stimulation (TTNS) Treatment in Spina Bifida Pediatric Patients With Neurogenic Bladder

Spina Bifida
Cairo University

Completed

OHRQoL and Parental Perception in a Group of Children and Adolescents With Down Syndrome: A Cross

Quality of Life | Down Syndrome | Oral Health

Egypt
Assistance Publique - Hôpitaux de Paris
Institut National de la Santé Et de la Recherche Médicale, France; University... and other collaborators

Active, not recruiting

Non Invasive Prenatal Diagnosis of Trisomy 21 by Genetic Analysis of Circulating Fetal Cells (ISETTRI21)

Trisomy 21

France
Central Hospital, Nancy, France

Unknown

Study of High Risk Non Invasive Prenatal Test Population

Trisomy 21
Eisai Inc.
Pfizer

Terminated

Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (Aricept) In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome, Aged 6 To 10

Cognitive Dysfunction | Down Syndrome

United States
Mayo Clinic

Terminated

Evaluation of Autonomic Function in Individuals With Cornelia de Lange Syndrome (CdLS)

Cornelia de Lange Syndrome

United States
Eisai Inc.
Pfizer

Terminated

Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (Aricept) In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome, Aged 11 To 17

Cognitive Dysfunction | Down Syndrome

United States
Roche Sequencing Solutions

Completed

Prenatal Test for Fetal Aneuploidy Detection

Aneuploidy | Trisomy 21

United States
Hadassah Medical Organization
Grumental

Completed

Comparison Between Tramadol Hcl and Other Analgesics in the Treatment of Renal Colic

Renal Calculus

Israel
National Institute of Neurological Disorders and...

Completed

Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors

Neoplasms | Kidney Neoplasms | Kidney Diseases | Retinal Diseases | Deafness

United States
Neuromed IRCCS

Recruiting

Neurophysiological Evaluation of Muscle Tone

Spasticity, Muscle | Muscle Tone Abnormalities | Rigidity, Muscle

Italy
Old Dominion University

Completed

Four-week Breathing Interventions on Gut Symptoms, Heart Rate Variability, and Psychological Measures in Runners

Anxiety | Visceral Pain | Gastrointestinal System--Abnormalities

United States
Pfizer

Completed

Efficacy And Safety Of Parecoxib 40mg vs. Ketoprofen 100mg In The Management Of Acute Renal Colic (NAP)

Pain

Brazil, Costa Rica, Chile, Ecuador, Honduras, Peru
Clinique Ovo

Active, not recruiting

Paternal Age and Fetal Aneuploidy

Trisomy 21

Canada
Baylor College of Medicine

Completed

Hypotension in Children With Down Syndrome With Anesthesia Induction

Hypotension on Induction

United States
University Hospital, Caen

Terminated

Non-invasive Screening of Fetal Trisomy 21 by Digital PCR (dPNI-T21)

Trisomy 21

France
Eisai Inc.
Pfizer

Terminated

Evaluating The Safety Of Donepezil Hydrochloride (Aricept) For Up To 1 Year In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome - Follow-Up To A 10-Week, Double-Blind, Placebo-Controlled Trial

Down Syndrome

United States
Corporacion Parc Tauli
Parc de Salut Mar

Completed

GH in Adults With PWS, Effect on Hypotonia Evaluated by Functional MRI, Relationship With Strength and Body Composition

Prader-Willi Syndrome

Spain
University Hospital, Toulouse

Completed

Tolerance of Intranasal Administration of OT in Prader-Willi Newborn Babies (OTBB)

Prader-Willi Syndrome

France
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Global Behavior and Periodontal Disease in Down's Syndrome Patients

Periodontal Diseases | Behavior

Brazil
Roche Sequencing Solutions
Perinatal Quality Foundation: Nuchal Translucency Quality Review

Completed

Non-invasive Chromosomal Examination of Trisomy Study (NEXT)

Trisomy 21

United States, Belgium, Netherlands, Sweden, Italy, Canada
University of Colorado, Denver
National Center for Advancing Translational Sciences (NCATS); Linda Crnic Institute... and other collaborators

Recruiting

The Crnic Institute Human Trisome Project Biobank (HTP)

Down Syndrome | Trisomy 21

United States
University Hospital, Grenoble

Completed

Diagnosis Accuracy of Noninvasive Screening by PCR Digital for Down Syndrom (DIgiT21)

Trisomy 21

France
Soleno Therapeutics, Inc.
Casimir Trials

Unknown

PWS Outcomes Assessment Study

Prader-Willi Syndrome

United States
Advocate Health Care

Completed

Parents as the Primary Sexuality Educators for Their Young Adults With Down Syndrome

Intellectual Disability | Parent-Child Relations | Down Syndrome | Sexuality

United States
Essentialis, Inc.

Unknown

A 5 Treatment Period Pharmacokinetic Study Evaluating Dose Proportionality and Food Effects of Diazoxide Choline Controlled-Release Tablet (DCCR)

Prader-Willi Syndrome
Kyorin University

Completed

Eyelash Line Resection for Entropion Associated With Down's Syndrome

Down's Syndrome

Japan
Doaa AL-Saleh

Completed

Correlation Between Neck Pain and Postural Abnormalities Among Female Office Workers at University of Dammam

NECK PAIN
Yonsei University

Withdrawn

The Correlation Between Renal Injury and Biomarkers in Pediatric Ureteropelvic Junction Obstruction Patients

Ureteropelvic Junction Obstruction

Korea, Republic of
Mario Negri Institute for Pharmacological Research

Completed

Sirolimus Treatment in Patients With Autosomal Dominant Polycystic Kidney Disease: Renal Efficacy and Safety (SIRENA)

Polycystic Kidney

Italy
Rajeev Chaudhry
Children's Healthcare of Atlanta

Terminated

Indwelling Double-J Ureteral Stent Versus Externalized Modified-Salle Stent for Pyeloplasty

Ureteropelvic Junction Obstruction

United States
CENTOGENE GmbH Rostock

Terminated

Biomarker for Alport Syndrome (BioAlport) (BioAlport)

Nephritis, Hereditary | Hematuria-Nephropathy-Deafness Syndrome

India, Sri Lanka, Albania, Georgia, Lithuania, Pakistan, Romania
Sonoran Spine Research and Education Foundation

Recruiting

Does Intrathecal Morphine Affect Outcomes in Spine Deformity Surgery

Low Back Pain

United States
US Department of Veterans Affairs

Completed

A Prospective Cohort Study of MR Abnormalities and Back Pain Risk

Low Back Pain

United States
CHU de Quebec-Universite Laval

Recruiting

Scaling a Decision Aid on Prenatal Screening for Trisomy 21, 18 and 13 (PEGASUS-II)

Decision Aid

Canada
Alberta Children's Hospital

Completed

Evaluating Pain Outcomes of Caudal vs Ilioinguinal Nerve Block in Children Undergoing Orchiopexy Repair

Pain, Postoperative | Testicle Undescended

Canada
Assistance Publique - Hôpitaux de Paris

Completed

Non Invasive Prenatal Testing of Down Syndrome (SAFE 21)

Down Syndrome

France
Sequenom, Inc.

Completed

Clinical Evaluation of the SEQureDx Trisomy Test in Low Risk Pregnancies

Down Syndrome | Aneuploidy | Noninvasive Prenatal Screening

United States
Shaare Zedek Medical Center

Unknown

Post Exercise Irisin Levels in PWS Patients

Prader Willi Syndrome

Clinical Trials on Neurologic Abnormalities

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Medical Conditions

Drug Interventions

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CROs in Angola

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