Clinical Trials on Neurological Impairment in Germany

Total 1535 results

Novartis Pharmaceuticals

Completed

Observation of Treatment Patterns With Lucentis in Approved Indications (OCEAN)

Neovascular AMD, Visual Impairment Due to DME, Visual Impairment Due to Macular Oedema Secondary to Branch or Central RVO, Visual Impairment Due to CNV

Germany
H. Lundbeck A/S

Completed

Pharmacokinetics Properties of Single Oral Dosing of Lu AE58054 in Subjects With Hepatic Impairment (Mild and Moderate) and in Healthy Subjects

Heptic Impairment

Germany
Novartis Pharmaceuticals

Withdrawn

Systemic VEGF Protein Dynamics Following Intravitreal Injections of Ranibizumab Versus Aflibercept in Patients With Visual Impairment Due to Diabetic Macular Edema (TIDE DME)

Visual Impairment Due to Diabetic Macular Edema

Germany
University Hospital, Bonn
Maximilian Kiebs, M.Sc. - University Hospital Bonn (Department of Medical...

Recruiting

Prediction of the Cognitive Effects of Electroconvulsive Therapy Via Machine Learning and Neuroimaging (CoEffECT)

Depression | Cognitive Impairment | Memory Impairment | ECT

Germany
EuroPharma, Inc.

Completed

Effects of an Adaptogenic Extract on Electrical Activity of the Brain in Elderly Subjects With Cognitive Impairment

Cognitive Impairment, Mild

Germany
Charite University, Berlin, Germany

Withdrawn

Influence of tDCS on Cortical Plasticity in Patients With Mild Cognitive Impairment (MCI)

Patients With Mild Cognitive Impairment

Germany
Charite University, Berlin, Germany

Completed

Modulation of Visual-Spatial Learning in Patients With Mild Cognitive Impairment (MCI) by tDCS

Mild Cognitive Impairment (MCI)

Germany
Vasopharm GmbH
Winicker Norimed GmbH

Completed

Effects of the NO-synthase Inhibitor VAS203 on Renal Function in Healthy Volunteers

Renal Function Impairment in Healthy Volunteers

Germany
Charite University, Berlin, Germany

Completed

Effects of Brain Stimulation During a Daytime Nap on Memory Consolidation in Patients With Mild Cognitive Impairment

Mild Cognitive Impairment, So Stated

Germany
Ludwig-Maximilians - University of Munich

Completed

Outcome Predictors of a Cognitive Intervention in aMCI (OutPreC MCI)

Amnestic Mild Cognitive Impairment

Germany
Charite University, Berlin, Germany

Withdrawn

Effects of Brain Stimulation During Nocturnal Sleep on Memory Consolidation in Patients With Mild Cognitive Impairments

Mild Cognitive Impairment, So Stated

Germany
University Medicine Greifswald
University of Greifswald

Recruiting

Cognitive Training and Brain Stimulation in Women With Post-chemotherapy Cognitive Impairment (NeuroMod-PCCI)

Breast Cancer | Cognitive Impairment

Germany
Novartis Pharmaceuticals

Completed

An Open-label, Parallel-group Study to Determine the Pharmacokinetics of a Single Dose of AFQ056 in Subjects With Renal Impairment Compared to Healthy Subjects

Mild Moderate | or Severe Renal Impairment

Germany
Charité Neurocure AG Flöel

Unknown

Chronic Aphasia - Improved by Intensive Training and Electrical Brain Stimulation (CATS)

Aphasia | Anomia (Word-Finding Impairment)

Germany
Janssen Sciences Ireland UC

Completed

A Study to Evaluate the Effect of Hepatic Impairment on JNJ-73763989

Hepatic Impairment

Germany
H. Lundbeck A/S

Completed

Study Investigating the Pharmacokinetic Properties of the Drug Lu AF35700 in Subjects With Liver Impairment and in Healthy Subjects

Hepatic Impairment

Germany
University of Magdeburg
EBS Technologies GmbH

Completed

Paraorbital-Occipital Electric Stimulation in Patients With Optic Neuropathy (BCT_optnerve)

Visual Impairment

Germany
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

Effect of Hepatic Impairment on M2951 (BTK Inhibitor) PK

Hepatic Impairment

Germany
Janssen Sciences Ireland UC

Completed

A Study to Evaluate the Effect of Hepatic Impairment on JNJ-56136379

Hepatic Impairment

Germany
Novartis Pharmaceuticals

Completed

Impact of Hepatic Impairment on the Pharmacokinetics of Deferasirox.

Hepatic Impairment

Germany
Poxel SA

Completed

Pharmacokinetics of Imeglimin in Hepatic Impaired Subjects

Hepatic Impairment

Germany
Robert Bosch Gesellschaft für Medizinische Forschung...
Norwegian University of Science and Technology

Completed

Evaluation of the Measurement Properties of a 5 Time Repeated Instrumented Timed Up and Go (5iTUG) (5iTUG)

Cognitive Impairment | Physical Disability | Gait Disorder, Sensorimotor | Balance | Activity of Daily Living | Measurement Properties of 5iTUG | Leg Strength

Germany
Novartis Pharmaceuticals

Completed

A Study of LCZ696 in Subjects With Mild and Moderate Hepatic Impairment Compared With Normal Healthy Volunteers

Hepatic Impairment

Germany
Newron Pharmaceuticals SPA

Completed

A Study to Assess the Effect of Hepatic Impairment on Safinamide Pharmacokinetics

Hepatic Impairment

Germany
Janssen-Cilag International NV

Completed

A Study of Orally Administered Pimodivir in Adult Participants With Hepatic Impairment

Hepatic Impairment

Germany
Janssen Research & Development, LLC

Terminated

A Study to Evaluate the Effect of Hepatic Impairment on the Pharmacokinetics of Erdafitinib

Hepatic Impairment

Germany
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effect of Hepatic Impairment on Lazertinib (JNJ-73841937)

Healthy | Hepatic Impairment

Germany
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effect of Hepatic Impairment on JNJ-42847922 in Adult Participants

Healthy | Hepatic Impairment

Germany
Idorsia Pharmaceuticals Ltd.

Completed

The Effect of Reduced Liver Function on Selatogrel Pharmacokinetics

Healthy Subjects | Hepatic Impairment

Germany
VectivBio AG

Completed

A Phase 1, Open-Label Evaluation of the Pharmacokinetics and Safety of a Single Dose of Apraglutide in Subjects With Normal and Impaired Hepatic Function

Hepatic Impairment

Germany, Slovakia
LG Life Sciences

Completed

Influence of Hepatic Impairment on Pharmacokinetic (PK) and Pharmacodynamic (PD) of Gemigliptin PK and PD After Multiple Oral Doses in Healthy White Volunteers

Hepatic Impairment

Germany
Novartis Pharmaceuticals

Completed

Pharmacokinetics of LCZ696 in Subjects With Mild and Moderate Renal Impairment Compared to Healthy Subjects With Normal Renal Function

Mild and Moderate Renal Impairment

Russian Federation, Germany, Serbia
Novo Nordisk A/S

Recruiting

A Research Study Looking at How a Single Dose of the Medicine Cagrilintide Behaves in Participants With Reduced Liver Function and in Healthy Participants With Normal Liver Function

Hepatic Impairment

Germany, Slovakia
Novartis Pharmaceuticals

Completed

Pharmacokinetics of RLX030 in Subjects With Mild, Moderate and Severe Hepatic Impairment Compared to Healthy Subjects

Hepatic Impairment

Germany, Russian Federation
University Medicine Greifswald

Terminated

Cognitive Impairment Following Elective Spine Surgery (CONFESS)

Cognitive Impairment | Postoperative Delirium | Spine Fusion

Germany
Tobias Moser

Recruiting

Otoferlin Patient Registry and Natural History Study

Hearing Impairment | Otoferlin-related Auditory Synaptopathy

Germany
Charite University, Berlin, Germany
German Federal Ministry of Education and Research

Unknown

Chronic Aphasia - Improved by Intensive Training and Electrical Brain Stimulation (CATS)

Post-Stroke Chronic Aphasia | Anomia (Word-retrieval Impairment)

Germany
Janssen Infectious Diseases BVBA

Completed

A Study to Assess Safety and Pharmacokinetics of Telaprevir in Patients With Hepatic Impairment

Hepatic Impairment

Germany, Czech Republic
Novartis Pharmaceuticals

Completed

Pharmacokinetic Study of BKM120 in Subjects With Hepatic Impairment

Hepatic Impairment

Germany, Russian Federation, Bulgaria
Charite University, Berlin, Germany
Berlin Institute of Health; Federal Agency for Disruptive Innovation - SPRIN-D

Completed

Evaluation of Safety of Contraloid Acetate in Patients With Mild Cognitive Impairment Due to Alzheimer's Disease

Mild Cognitive Impairment Due to Alzheimer's Disease

Germany
Novartis Pharmaceuticals

Completed

A Study to Evaluate the Pharmacokinetics of AFQ056 in Subjects With Hepatic Impairment Compared to Healthy Subjects

Hepatic Impairment

Germany, United States, Hungary
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Evaluate ID-085 in People With Mild, Moderate, and Severe Kidney Disease

Renal Impairment

Germany
Charite University, Berlin, Germany
German Federal Ministry of Education and Research

Completed

Effects of Dietary Interventions on the Brain in Mild Cognitive Impairment (MCI)

Mild Cognitive Impairment

Germany
Polyphor Ltd.

Completed

Pharmacokinetics and Safety of POL7080 in Patients With Renal Impairment

Renal Impairment

Germany
Sanofi

Completed

Pharmacokinetic and Tolerability Study of 14 mg Single Dose of Teriflunomide in Subjects With Severe Renal Impairment

Renal Impairment

Germany
Wuerzburg University Hospital

Withdrawn

Cognitive Ability Training for Seniors With Mild Cognitive Impairment (MICE)

Mild Cognitive Impairment

Germany
Merck KGaA, Darmstadt, Germany

Completed

Effect of Renal Impairment on Evobrutinib Pharmacokinetics (PK)

Renal Impairment

Germany
Charite University, Berlin, Germany
German Research Foundation

Completed

Impact of Transcranial Direct Current Stimulation on Language Functions in Mild Cognitive Impairment (STIMCI)

Mild Cognitive Impairment

Germany
Nycomed
NPS Pharma

Completed

Pharmacokinetics of 10 mg Teduglutide in Subjects With Renal Impairment Compared to Healthy Subjects With Normal Renal Function

Renal Impairment

Germany
AstraZeneca

Completed

Safety Study of AZD5672 in Renally Impaired Subjects

Renal Impairment

Germany

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