Clinical Trials on Neuronal Plasticity in United Kingdom

Total 947 results

Ipsen

Completed

A Single Centre, Prospective, Observational Study to Assess the Use of the Rehabilitation Tool, GripAble, in Patients With Upper Limb Spasticity Receiving Botulinum Toxin-A (BoNT-A) in the United Kingdom (UK).

Upper Limb Spasticity (ULS)

United Kingdom
REGENXBIO Inc.

Active, not recruiting

A First-in-Human Study in Pediatric Patients With Ocular CLN2 Disease

Neuronal Ceroid Lipofuscinosis Type 2

United Kingdom
Ipsen

Completed

A Study to Review Treatment Outcomes From Treatment With Dysport® Injections in Adults for Upper and/or Lower Limb Focal Spasticity (DYSCOVER)

Upper and/or Lower Limb Focal Spasticity

United Kingdom
Neurogene Inc.

Recruiting

Gene Therapy Study for Children With CLN5 Batten Disease (CLN5-200)

Neuronal Ceroid Lipofuscinosis CLN5

United States, United Kingdom
Ipsen

Completed

A Study to Assess Treatment Outcomes of abobotulinumtoxinA and onabotulinumtoxinA Treatments in Real Life Practice in Toxin-naïve Adult Patients With Limb Spasticity.

Spasticity Related to Any Cause Except Cerebral Palsy

United Kingdom
BioMarin Pharmaceutical

Completed

A Phase 1/2 Open-Label Dose-Escalation Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Efficacy of Intracerebroventricular BMN 190 in Patients With Late-Infantile Neuronal Ceroid Lipofuscinosis (CLN2) Disease

Batten Disease | CLN2 Disease | Late-Infantile Neuronal Ceroid Lipofuscinosis Type 2 | Jansky-Bielschowsky Disease

United States, Italy, Germany, United Kingdom
BioMarin Pharmaceutical

Completed

A Safety, Tolerability, and Efficacy Study of Intracerebroventricular BMN 190 in Pediatric Patients < 18 Years of Age With CLN2 Disease

Batten Disease | CLN2 Disease | Late-Infantile Neuronal Ceroid Lipofuscinosis Type 2 | Jansky-Bielschowsky Disease | CLN2 Disorder

United States, Germany, Italy, United Kingdom
BioMarin Pharmaceutical

Completed

An Extension Study to Evaluate the Long-Term Efficacy and Safety of BMN 190 in Patients With CLN2 Disease

Batten Disease | CLN2 Disease | Late-Infantile Neuronal Ceroid Lipofuscinosis Type 2 | Jansky-Bielschowsky Disease | CLN2 Disorder

United States, Germany, Italy, United Kingdom
Johns Hopkins University
Saluda Medical Pty Ltd

Not yet recruiting

Closed Loop Spinal Cord Stimulation for Neuromodulation of Upper Motor Neuron Lesion Spasticity (CLONUS)

Chronic Pain | Spasticity as Sequela of Stroke | Upper Motor Neuron Lesion

United States
Canbex Therapeutics Ltd

Completed

Study of VSN16R for the Treatment of Spasticity in Multiple Sclerosis

Spasticity in People With Multiple Sclerosis

United Kingdom
Ipsen

Completed

Validation of the Spasticity Related Quality of Life Questionnaire (SQOL-6D)

Spasticity, Muscle

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Multi-channel Stimulation for Post Stroke Spasticity (MUSTS) (MUSTS)

Stroke | Muscle Spasticity

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Assessment of the Effects of Sheffield Support Snood in MND Patients

Motor Neurone Disease

United Kingdom
Robert Jones and Agnes Hunt Orthopaedic and District...

Recruiting

Pulsed Magnetic Stimulation - Managing Spasticity in Spinal Cord Injury (OsStim)

Spinal Cord Injuries

United Kingdom
Eunice Kennedy Shriver National Institute of Child...

Completed

Cystagon to Treat Infantile Neuronal Ceroid Lipofuscinosis

Infantile Neronal Ceroid Lipofuscinosis

United States
Queen Margaret University

Unknown

Morton's Neuroma: Manipulation Versus Steroid Injection

Neuroma, Human Forefoot

United Kingdom
Jazz Pharmaceuticals

Completed

A Study of the Safety and Effectiveness of Sativex®, for the Relief of Symptoms of Spasticity in Subjects, From Phase B, With Multiple Sclerosis (MS)

Multiple Sclerosis | Spasticity

United Kingdom
University of Rochester

Recruiting

Clinical and Neuropsychological Investigations in Batten Disease

Batten Disease | Neuronal Ceroid Lipofuscinosis | Neuronal Ceroid Lipofuscinosis CLN6 | Neuronal Ceroid Lipofuscinosis CLN3 | Neuronal Ceroid Lipofuscinosis CLN5 | Neuronal Ceroid Lipofuscinosis CLN1 | Neuronal Ceroid Lipofuscinosis CLN2 | Neuronal Ceroid Lipofuscinosis CLN7 | Neuronal Ceroid Lipofuscinosis... and other conditions

United States
Sandwell & West Birmingham Hospitals NHS Trust
Stroke Research Network; Keele University

Completed

Early Use of Botulinum Toxin in Spasticity Post Stroke. (EUBoSS)

Stroke | Muscle Spasticity | Contracture

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust

Unknown

A Programme for Amyotrophic Lateral Sclerosis Care in Europe (ALS-CarE)

ALS (Amyotrophic Lateral Sclerosis) | MND (Motor Neurone DIsease)

United Kingdom
Jazz Pharmaceuticals

Completed

A Study of Sativex® for Relief of Spasticity in Subjects With Multiple Sclerosis.

Multiple Sclerosis | Spasticity

United Kingdom
Jazz Pharmaceuticals

Completed

Evaluate the Maintenance of Effect After Long-term Treatment With Sativex® in Subjects With Symptoms of Spasticity Due to Multiple Sclerosis

Multiple Sclerosis | Spasticity

United Kingdom
Dundee Podiatry Clinic
Queen Margaret University

Completed

Morton's Neuroma: Manipulation Versus Steroid Injection

Morton Neuroma

United Kingdom
University of Birmingham

Completed

Effects of Intense Exercise on Neural Responses to Food.

Neural Responses | Appetite Hormones | Subjective Appetite Sensations

United Kingdom
Merz Pharmaceuticals GmbH

Completed

IncobotulinumtoxinA (Xeomin) for Upper Limb Spasticity (NT-Spin)

Upper Limb Spasticity

France, Spain, Switzerland, United Kingdom, Italy, Austria, Germany, Portugal
Institute of Child Health

Completed

Prevention of Neural Tube Defects by Inositol in Conjunction With Folic Acid (PONTI Study)

Recurrent Neural Tube Defects

United Kingdom
Guy's and St Thomas' NHS Foundation Trust

Completed

The Relationship Between Arterial Stiffness and Respiratory Failure in Motor Neurone Disease

Motor Neurone Disease | Hypoxemia and/or Hypercapnia

United Kingdom
MedtronicNeuro

Completed

SISTERS: Spasticity In Stroke Study - Randomized Study (SISTERS)

Severe Spasticity

Belgium, Spain, United States, Austria, Germany, Italy, Netherlands, Slovenia, United Kingdom
Stanford University
National Eye Institute (NEI)

Enrolling by invitation

Measuring rTMS-induced Neuroplasticity With EEG Steady-state Visual-evoked Potentials

Repetitive Transcranial Magnetic Stimulation | Visual Attention | Visual Cortical Plasticity

United States
University of Massachusetts, Worcester

Completed

Neuronal Processing of Diacritics: An fMRI Study

Neuronal Processing of Diacritics

United States
University of Reading

Completed

Effects of Cocoa Flavanols on Human Cognitive Function

Neural Degeneration

United Kingdom
Jazz Pharmaceuticals

Completed

A Long-term Safety Extension Study of Delta-9-tetrahydrocannabinol (THC) and Cannabidiol (CBD) in Multiple Sclerosis

Multiple Sclerosis | Spasticity

United Kingdom
Medtronic

Completed

Medtronic PSR TDD PMCF

Chronic Pain | Spasticity, Muscle

Belgium, Spain, Czechia, France, Netherlands, Slovenia, Switzerland, United Kingdom
Weill Medical College of Cornell University
National Institute of Neurological Disorders and Stroke (NINDS); National Institutes... and other collaborators

Completed

Genotype-Phenotype Correlations of Late Infantile Neuronal Ceroid Lipofuscinosis

Batten Disease | Late Infantile Neuronal Ceroid Lipofuscinosis

United States
Weill Medical College of Cornell University

Terminated

Collection of Cerebrospinal Fluid in Healthy Children

Batten Disease | Late Infantile Neuronal Ceroid Lipofuscinosis

United States
Jazz Pharmaceuticals

Completed

A Study of the Long-term Safety of Sativex Use

Pain | Multiple Sclerosis | Spasticity

United Kingdom
Kemin Foods LC

Completed

Evaluation of the Benefits of FloraGLO™ Lutein on Skin Health

Healthy | Aging | Hydration | Wrinkle | Skin Elasticity

United States
Eunice Kennedy Shriver National Institute of Child...

Recruiting

Investigations of Juvenile Neuronal Ceroid Lipofuscinosis

Batten Disease | Juvenile Neuronal Ceroid Lipofuscinosis (CLN3)

United States
Amicus Therapeutics

Completed

Gene Therapy for Children With Variant Late Infantile Neuronal Ceroid Lipofuscinosis 6 (vLINCL6) Disease

Variant Late-Infantile Neuronal Ceroid Lipofuscinosis

United States
Weill Medical College of Cornell University
National Institutes of Health (NIH)

Completed

Safety Study of a Gene Transfer Vector (Rh.10) for Children With Late Infantile Neuronal Ceroid Lipofuscinosis (LINCL)

Batten Disease | Late-Infantile Neuronal Ceroid Lipofuscinosis

United States
Weill Medical College of Cornell University

Completed

AAVRh.10 Administered to Children With Late Infantile Neuronal Ceroid Lipofuscinosis

Batten Disease | Late Infantile Neuronal Ceroid Lipofuscinosis

United States
Amicus Therapeutics

Terminated

Natural History Study of Batten Disease

Batten Disease | Neuronal Ceroid Lipofuscinosis CLN6 | Neuronal Ceroid Lipofuscinosis CLN3

United States
Jazz Pharmaceuticals

Completed

A Safety, Efficacy and Tolerability Study of Sativex for the Treatment of Spasticity in Children Aged 8 to 18 Years

Cerebral Palsy

Czechia, Israel, United Kingdom
Allergan

Completed

BOTOX® Economic Spasticity Trial (BEST)

Muscle Spasticity

Canada, Sweden, Germany, United Kingdom
University College, London
University College London Hospitals

Unknown

Novel Multimodality Imaging for Navigation in Skull Base Surgery (SBN)

Vestibular Schwannoma

United Kingdom
King's College Hospital NHS Trust
Guy's and St Thomas' NHS Foundation Trust

Recruiting

Use of DTT to Define Facial Nerve Position in Vestibular Schwannomas

Vestibular Schwannoma

United Kingdom
Weill Medical College of Cornell University
Nathan's Battle Foundation

Completed

Safety Study of a Gene Transfer Vector for Children With Late Infantile Neuronal Ceroid Lipofuscinosis

Batten Disease | Late Infantile Neuronal Ceroid Lipofuscinosis

United States
Pacira Pharmaceuticals, Inc

Recruiting

Study to Assess the Efficacy and Safety of Iovera®° System in Subjects With Upper Extremity Spasticity

Spasticity, Cerebral or Spinal Condition

United States
Pacira Pharmaceuticals, Inc

Completed

Study Evaluating Treatment of Upper Limb Spasticity Using the Cryo-Touch III Device

Upper Limb Spasticity

United States
Shirley Ryan AbilityLab

Suspended

Robotic Interventions for Spasticity Treatment

Stroke | Spasticity, Muscle

United States

Clinical Trials on Neuronal Plasticity in United Kingdom

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