Search clinical trials for: TNF-alpha inhibitors

Total 69271 results

Huashan Hospital
The First Affiliated Hospital with Nanjing Medical University; Peking University... and other collaborators

Recruiting

Real-world Study Optimizing Nucleotide-analogues

Hepatitis B, Chronic

China
Assistance Publique - Hôpitaux de Paris

Unknown

The RATIO: Registry of Infections and Lymphoma in Patients Treated With TNF-a Antagonists

Rheumatoid Arthritis | Psoriasis | Crohn's Disease | Ankylosing Spondylitis

France
Kaohsiung Medical University Chung-Ho Memorial...

Unknown

Genetic Polymorphisms of TNF-α Promoter and HBV Genotype on Outcome of HBV-Related Chronic Liver Disease

Hepatocellular Carcinoma | Chronic Liver Disease

Taiwan
Rigshospitalet, Denmark
University of Copenhagen; Copenhagen Muscle Research Centre, Rigshospitalet...

Completed

The Acute Effects of Low-dose TNF-α on Glucose Metabolism and β-cell Function in Humans

Diabetes Type 2

Denmark
Universidade Federal do Rio de Janeiro

Unknown

99mTc-anti-TNF-alpha Scintigraphy in the Evaluation of Inflammatory Processes Activity

Arthritis | Psoriatic Arthritis

Brazil
Kaohsiung Medical University Chung-Ho Memorial...

Completed

Genetic Polymorphisms of Interleukin-1B and TNF-A and HBV-Related Hepatocellular Carcinoma

Hepatitis B | Hepatocellular Carcinoma | Chronic Liver Disease

Taiwan
Central Hospital, Nancy, France

Completed

C.O.R.P.U.S.: Observational Cohort of Adult and Child Inflammatory Arthritis in France

Arthritis, Rheumatoid | Arthritis, Psoriatic | Spondylitis, Ankylosing | Arthitis, Juvenile Idiopathic

France
Neovacs

Completed

Immunogenicity and Safety of TNFa Kinoid in Rheumatoid Arthritis With Secondary Resistance to TNFa Antagonists

Rheumatoid Arthritis

Belgium, France, Bulgaria, Argentina, Croatia, Chile, Romania
Medical University of Graz

Completed

Long-term Outcome of TNF Alpha Therapy in IBD

IBD

Austria
Biologics & Biosimilars Collective Intelligence...
Merck Sharp & Dohme LLC; Pfizer; AbbVie; University of Pittsburgh; Boehringer Ingelheim and other collaborators

Completed

Incidence of Hospitalizations for Serious Infections in Patients Receiving Biologic Anti-Inflammatories for Rheumatologic, Psoriatic, and Gastrointestinal Conditions: A Descriptive Analysis

Rheumatoid Arthritis | Psoriasis | Psoriatic Arthritis | Inflammatory Bowel Disease | Ankylosing Spondylitis
Kaohsiung Medical University Chung-Ho Memorial...

Unknown

Genetic Polymorphisms of Interleukin-10 and TNF-α on Outcome of HCV-Related Chronic Liver Disease

Hepatitis C Virus Infection | Chronic Liver Disease

Taiwan
Hospital del Río Hortega
Francisco Javier Garcia Alonso; Jesús Barrio

Recruiting

Influence of HLA-DQA1*05 Genotype in Adults With Anti-TNF Treatment With Proactive Therapeutic Drug Monitoring. (Proa-DQ)

Inflammatory Bowel Diseases | Drug Monitoring

Spain
Gilead Sciences

Completed

Tenofovir Alafenamide Versus Tenofovir Disoproxil Fumarate for Treatment of Hepatitis B e Antigen-Negative Hepatitis B (China)

HBV | Chronic HBV Infections

China
Gilead Sciences

Completed

Study to Evaluate Efficacy and Safety of Switching From TDF to TAF in Adults With Chronic Hepatitis B Who Are Virologically Suppressed

Chronic Hepatitis B

United States, Canada, United Kingdom, Hong Kong, Spain, Taiwan, Korea, Republic of, Italy
European Organisation for Research and Treatment...

Completed

NGR-TNF in Treating Patients With Advanced Solid Tumors

Kidney Cancer | Head and Neck Cancer | Colorectal Cancer | Unspecified Adult Solid Tumor, Protocol Specific

Germany, Netherlands
Gilead Sciences

Completed

Study to Compare Tenofovir Alafenamide (TAF) Versus Tenofovir Disoproxil Fumarate (TDF) in Participants With Chronic Hepatitis B Infection Who Are Negative for Hepatitis B e Antigen

HBeAg-negative Chronic Hepatitis B

Hong Kong, United States, United Kingdom, Canada, Australia, Spain, Taiwan, India, Japan, Poland, Romania, Russian Federation, Korea, Republic of, Italy, New Zealand, France, Turkey
Gilead Sciences

Completed

Tenofovir Alafenamide Versus Tenofovir Disoproxil Fumarate for Treatment of Hepatitis B e Antigen-Positive Hepatitis B (China)

HBV | Chronic HBV Infections

China
Gilead Sciences

Completed

Study to Compare Tenofovir Alafenamide (TAF) Versus Tenofovir Disoproxil Fumarate (TDF) in Participants With Chronic Hepatitis B Infection Who Are Positive for Hepatitis B e Antigen

HBeAg-positive Chronic Hepatitis B

Hong Kong, Korea, Republic of, United States, Taiwan, United Kingdom, France, Australia, Spain, Bulgaria, Canada, India, Italy, Japan, New Zealand, Poland, Romania, Russian Federation, Singapore, Turkey
Hamamatsu University
Yokoyama Foundation for Clinical Pharmacology

Unknown

Cytokine Gene Polymorphisms in Gastric Diseases

Gastric Cancer | Gastric Ulcer | Duodenal Ulcer

Japan
University of Campinas, Brazil

Completed

Effects of the TNF-alpha Inhibiton on Hemodynamic Parameters in Resistant Hypertension

Hypertension

Brazil
Prof. Roberto Giacomelli

Terminated

Clinical Study to Evaluate the Efficacy of Anakinra in Patients With Rheumatoid Arthritis and Diabetes (TRACK)

Diabetes Mellitus, Type 2 | Arthritis, Rheumatoid

Italy
NHS Greater Glasgow and Clyde
University of Glasgow; NHS Ayrshire and Arran; Golden Jubilee National Hospital

Not yet recruiting

CharacterisatiON of carDiac funCTion in Intensive Care Unit Survivors of Sepsis. (CONDUCT-ICU)

Heart Failure | Sepsis | Septic Shock | Myocarditis

United Kingdom
Kaohsiung Medical University Chung-Ho Memorial...

Completed

Relationship Between Polymorphism of Heat Shock Protein 70 Gene and Hepatocellular Carcinoma (HSP70)

Hepatocellular Carcinoma

Taiwan
Gunay ER

Completed

Enthesitis Assessment Before and After Anti-Tumor Necrosis Factor Treatment in Spondyloarthritis

Spondyloarthritis | Enthesitis | Anti-Tumor Necrosis Factor Drugs
Cairo University

Completed

Intravitreal Infliximab in Refractory Uveitis in Behcet's Disease: A Safety and Efficacy Clinical Study

Uveitis | Behçet's Disease
Protalix

Completed

Study to Evaluate the Safety and Pharmacokinetics of Oral OPRX-106 (TNFR-Fc Fusion Protein) in Healthy Volunteers

Human Volunteer

Israel
Grifols Therapeutics LLC

Completed

Safety and Tolerability Trial of Inhaled Alpha1-Proteinase Inhibitor (Human), Hydrophobic Chromatography Process (Alpha-1 HC) in Subjects With Cystic Fibrosis

Cystic Fibrosis

United States
Aarhus University Hospital
University of Aarhus; Lundbeck Foundation

Completed

Endotoxin & Cytokines. Do Protein Loss and Metabolic Effects Depend on Central Nervous System (CNS) Activation of Stress Hormones or on Local Mechanisms in Muscle and Fat?

Glucose Metabolism Disorders | Inflammation

Denmark
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Efficacy and Safety of CNTO328 Plus Best Supportive Care in Multicentric Castleman's Disease

Multicentric Castleman's Disease

United States, Canada, France, United Kingdom, China, Germany, Taiwan, Spain, Belgium, Israel, India, Korea, Republic of, Netherlands, Singapore, Brazil, Russian Federation, New Zealand, Hungary, Norway, Australia, Egypt, Hong Kong, Malaysi...
Grifols Therapeutics LLC

Terminated

Study of Human Plasma-Derived Alpha1-Proteinase Inhibitor in Subjects With New-Onset Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

United States
Hoffmann-La Roche

Completed

A Comparative Study to Observe the Effect of Concomitant Use of Corticosteroid Treatment in Rheumatoid Arthritis (RA) Participants Who Are Treated With a Tumor Necrosis Factor (TNF) Inhibitor or Tocilizumab (TCZ) as Their Second Biological Treatment.

Rheumatoid Arthritis

Sweden
Shanghai Public Health Clinical Center
Yunnan AIDS Care Center; Xixi Hospital of Hangzhou

Active, not recruiting

Switching From TDF-based Antiretroviral Therapy Regimens to B/F/TAF in Virally Suppressed Adults With HIV-1 Infection

HIV-1-infection

China
Grifols Therapeutics LLC

Completed

Safety and Pharmacokinetics of Alpha-1 Proteinase Inhibitor in Subjects With Alpha1-Antitrypsin Deficiency (SPARK)

Emphysema | Alpha 1-antitrypsin Deficiency (AATD)

United States
Centre Hospitalier Universitaire de Nīmes
Pfizer

Completed

Evaluation of Tumour Necrosis Factor Alpha (TNFα) Blockers in Early Rheumatoid Arthritis in France

Rheumatoid Arthritis
Shanghai Zhongshan Hospital

Recruiting

A Pilot Study in Severe Patients With Takayasu Arteritis.

Takayasu Arteritis | Treatment | Tocilizumab | Adalimumab

China
Assistance Publique - Hôpitaux de Paris

Recruiting

Evaluation of TNF-alpha Antagonists (Infliximab) Withdrawal in Sarcoidosis (TAWIS)

Sarcoidosis

France
Gilead Sciences

Active, not recruiting

Study to Evaluate the Safety and Efficacy of Emtricitabine and Tenofovir Alafenamide (F/TAF) Fixed-Dose Combination Once Daily for Pre-Exposure Prophylaxis in Men and Transgender Women Who Have Sex With Men and Are At Risk of HIV-1 Infection (DISCOVER)

Pre-Exposure Prophylaxis of HIV-1 Infection

United States, Austria, Denmark, United Kingdom, Netherlands, Italy, Germany, Canada, Ireland, France, Spain
Gilead Sciences

Completed

Study to Evaluate Switching From a Regimen Consisting of Efavirenz/Emtricitabine/Tenofovir Disoproxil Fumarate (EFV/FTC/TDF) Fixed Dose Combination (FDC) to Emtricitabine/Rilpivirine/Tenofovir Alafenamide (FTC/RPV/TAF) FDC in Virologically-Suppressed, HIV-1 Infected Adults

HIV-1 Infection

Spain, United States, United Kingdom, Switzerland, Germany, Canada, France, Belgium, Puerto Rico
Pfizer

Completed

Correlation Between Beliefs About Medicine and Objective Measures of Efficacy and Safety in Rheumatoid Arthritis (RA) (CONTENT)

Rheumatoid Arthritis

Belgium
Beijing Ditan Hospital

Unknown

Effect and Safety of Propofol Fumarate for Mother-to-child Blocking of Hepatitis B

Chronic Hepatitis B Infection | High Viral Load

China
Malmö University
University of Copenhagen

Completed

Minimally Invasive Volume Augmentation of Papillae Around Implant Restorations With Hyaluronic Acid Injection

Interdental Papilla Augmentation

Sweden
HaEmek Medical Center, Israel
University of Toronto; Mount Sinai Hospital, Canada

Completed

The Influence of Biologcal Treatment on the Short-Term Complications of Surgery in Patients With Inflematory Bowel Disease.

Ulcerative Colitis | Anti TNF Therapy | Ileal Pouch Anal Anastomosis (IPAA)
Takeda

Completed

Sub-optimal Response to Anti-Tumor Necrosis Factor's in Inflammatory Bowel Disease in Emerging Markets

Inflammatory Bowel Diseases | Crohn Disease | Colitis, Ulcerative

China, Korea, Republic of, Taiwan, Russian Federation, Turkey, Argentina, Colombia, Mexico, Saudi Arabia, Singapore
Gilead Sciences

Completed

Switch Study to Evaluate F/TAF in HIV-1 Positive Participants Who Are Virologically Suppressed on Regimens Containing FTC/TDF

HIV-1 Infection

United States, United Kingdom, Canada, France, Italy, Puerto Rico, Belgium
Unity Health Toronto
Dicofarm; University of Toronto, Toronto

Completed

Effect of Konjac-mannan in Individuals With Insulin-Resistance Syndrome

Insulin Resistance Syndrome
Gilead Sciences

Completed

Switch Study to Evaluate the Safety and Efficacy of Emtricitabine/Rilpivirine/Tenofovir Alafenamide (FTC/RPV/TAF) Fixed Dose Combination (FDC) in HIV-1 Positive Adults Who Are Virologically Suppressed on Emtricitabine/Rilpivirine/Tenofovir Disoproxil Fumarate (FTC/RPV/TDF)

HIV-1 Infection

United States, Spain, United Kingdom, Netherlands, Germany, Canada, Sweden, Switzerland, Italy, Belgium, Puerto Rico, France
Pfizer

Completed

Study Looking at Longitudinal Changes in Fatigue and Health Status in Rheumatoid Arthritis (RA) Patients Treated With Subcutaneous Anti-TNF-α Therapy

Rheumatoid Arthritis

Belgium
Neovacs

Completed

Clinical Efficacy of TNFa Kinoid in Crohn's Disease Patients

Crohn's Disease

Germany, Belgium, France, Romania, Bulgaria, Croatia, Czech Republic, Hungary, Netherlands
Grifols Therapeutics LLC

Terminated

Study to Evaluate the Safety and Efficacy of Liquid Alpha1-Proteinase Inhibitor (Human) in Hospitalized Participants With Coronavirus Disease (COVID-19)

COVID-19

United States, Brazil, Chile, Colombia, Mexico
Gilead Sciences

Completed

Safety and Efficacy of Bictegravir/Emtricitabine/Tenofovir Alafenamide Versus Dolutegravir + Emtricitabine/Tenofovir Disoproxil Fumarate in Treatment Naive, HIV-1 and Hepatitis B Co-Infected Adults (Alliance)

HIV-1/HBV Co-Infection

Spain, Taiwan, Korea, Republic of, Thailand, Hong Kong, Japan, France, Turkey, Puerto Rico, Malaysia, United States, China, Dominican Republic, Greece

Search clinical trials for: TNF-alpha inhibitors

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Netherlands

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations