Clinical Trials on Nicotine Dependence in Canada

Total 86 results

Centre for Addiction and Mental Health

Completed

A Dietary Supplement for Early Cigarette Withdrawal (CIGAR)

Nicotine Dependence, Cigarettes, With Withdrawal

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Active, not recruiting

The INITIATE Study: Initiating Nicotine Dependence Treatment for Smokers Admitted to Emergency Departments (INITIATE)

Nicotine Dependence, Cigarettes | Nicotine Withdrawal

Canada
Centre for Addiction and Mental Health
Canadian Institutes of Health Research (CIHR)

Completed

Use of Pharmacotherapy to Reduce Cue-responsiveness in Smokers

Nicotine Dependence | Tobacco Dependence

Canada
Centre for Addiction and Mental Health
Canadian Cancer Society (CCS)

Recruiting

Smoking Cessation and Menstrual Cycle Phase (MC-NRT)

Smoking Cessation | Tobacco Smoking | Substance Use Disorders | Nicotine Dependence | Nicotine Use Disorder

Canada
Centre for Addiction and Mental Health

Completed

Smoking While on Transdermal Nicotine Replacement Therapy: Effects on Craving and Cessation

Nicotine Dependence

Canada
Centre for Addiction and Mental Health

Completed

Initial Screening of Gemfibrozil as a Novel Treatment for Tobacco Addiction

Nicotine Dependence

Canada
Centre for Addiction and Mental Health
Pfizer; Ontario Lung Association

Completed

The Effect of Varenicline on D2/D3 Receptor Binding in Smokers

Nicotine Dependence

Canada
Centre for Addiction and Mental Health
Ontario Lung Association

Terminated

Prazosin for Smoking Cessation

Nicotine Dependence

Canada
Centre for Addiction and Mental Health

Completed

Nicotine Metabolizers and [11C]-(+)-PHNO (MET)

Nicotine Dependence

Canada
Centre for Addiction and Mental Health
Nuraleve, Inc.

Withdrawn

Transcranial Direct Current Stimulation in a Smoking Cessation Trial (tDCS)

Nicotine Dependence

Canada
Centre for Addiction and Mental Health

Terminated

Efficacy and Neural Correlates of Personalized Treatment With Transdermal Nicotine Replacement (iT-NRT)

Tobacco Use Disorder | Nicotine Dependence

Canada
Centre for Addiction and Mental Health
Global Research Awards for Nicotine Dependence (GRAND)

Completed

The MATCH (Medication Aids for Tobacco Cessation and Health) Study (MATCH)

Tobacco Use Disorder | Nicotine Dependence

Canada
Centre for Addiction and Mental Health
Canadian Tobacco Control Research Initiative

Terminated

Baclofen for Smoking Cessation in a Non-Psychiatric Population (Baclofen)

Nicotine Dependence

Canada
Centre for Addiction and Mental Health
Canadian Tobacco Control Research Initiative

Terminated

Testing a Full Substitution Therapy Approach As Treatment of Tobacco Dependence

Nicotine Dependence

Canada
Centre for Addiction and Mental Health
Ottawa Heart Institute Research Corporation; Canadian Cancer Society (CCS)

Completed

Personalized Dosing of Nicotine Replacement (NRT to Effect)

Tobacco Use Disorder | Nicotine Dependence

Canada
Centre for Addiction and Mental Health
Canadian Institutes of Health Research (CIHR); Canadian Tobacco Control Research...

Completed

Study of Varenicline (Champix) for Smoking Cessation/Reduction in Patients With Bipolar Disorder

Nicotine Dependence

Canada
Centre for Addiction and Mental Health

Completed

Electronic Cigarettes in Daily Dependent Smokers

Nicotine Dependence | Substance Withdrawal Syndrome

Canada
Centre for Addiction and Mental Health
Canadian Psychiatric Research Foundation

Completed

Neural Inhibition as a Mechanism of Nicotine Dependence Among Persons With Schizophrenia

Smoking | Schizophrenia | Schizoaffective Disorder | Psychosis | Nicotine Dependence | Schizophreniform Disorders

Canada
Ottawa Hospital Research Institute

Recruiting

A Healthy People Initiative: Building the Socio-Economic Capital of Low Income Population At-Risk for HIV and Hepatitis-C

Substance Use Disorders | Nicotine Dependence

Canada
Centre for Addiction and Mental Health

Not yet recruiting

ACT for Methamphetamine Use Disorder in Women and Gender Non-Conforming Individuals

Methamphetamine-dependence | Methamphetamine Abuse

Canada
University of Cincinnati
National Institute on Drug Abuse (NIDA)

Completed

Safety Assessment of Potential Interactions Between IV Methamphetamine and Osmotic-Release Methylphenidate (OROS-MPH)

Methamphetamine Dependence | Methamphetamine Abuse

United States, Canada
Marco Leyton

Active, not recruiting

Investigation of Cigarette Cravings in Smokers

Tobacco Use | Addiction Nicotine | Cigarette Smoking

Canada
Centre for Addiction and Mental Health
Canadian Institutes of Health Research (CIHR)

Completed

Effect of Varenicline on Reactivity to Smoking and Drinking Cues

Alcohol Dependence | Tobacco Dependence

Canada
University of British Columbia
Canadian Institutes of Health Research (CIHR); Providence Healthcare; Innerchange...

Completed

Study to Assess Longer-term Opioid Medication Effectiveness (SALOME) (SALOME)

Heroin Dependence | Opioid Dependence

Canada
Centre for Addiction and Mental Health

Completed

Naltrexone in the Treatment of Concurrent Alcohol Dependence and Pathological Gambling

Concurrent Alcohol Dependence and Pathological Gambling

Canada, Finland
Empower Research Inc

Completed

Exploring Medically Perceived Benefits, Use and Interest in Psychedelics and Cannabinoids (EMPOWER)

Depressive Disorder | Depression | PTSD | Anxiety Disorders | Anxiety | Psychological | Psychedelic Experiences | Psychedelic Drug Dependence

Canada
Centre for Addiction and Mental Health
Canadian Institutes of Health Research (CIHR)

Completed

Effects of rTMS on Cigarette Smoking and Cognition in Schizophrenia (rTMSsmokelab)

Schizophrenia | Nicotine Addiction

Canada
University of Calgary

Recruiting

Novel Use of Probenecid to Alleviate Symptoms of Opioid Withdrawal

Chronic Pain | Drug Dependence of Morphine Type | Symptom, Withdrawal

Canada
Centre for Addiction and Mental Health
American Foundation for Suicide Prevention

Completed

Efficacy of Cognitive Bias Modification in Residential Treatment for Addiction

Substance Dependence

Canada
Centre for Addiction and Mental Health

Completed

Online Cognitive Behavioural Therapy for Addiction: Efficacy and Cost-Effectiveness in a Pragmatic Clinical Trial

Substance Dependence

Canada
Centre de Recherche de l'Institut Universitaire...
Canadian Institutes of Health Research (CIHR); Université de Sherbrooke; Laval... and other collaborators

Completed

How to Ease the Withdrawal of Tranquilizers Among Older Consumers?

Drug Dependence

Canada
Centre for Addiction and Mental Health
National Institute on Drug Abuse (NIDA)

Completed

Sativex and Behavioral-relapse Prevention Strategy in Cannabis Dependence

Cannabis Dependence

Canada
Douglas Mental Health University Institute

Completed

Memory Reconsolidation Blockade for Treating Drug Addiction

Substance Dependence

Canada
Centre for Addiction and Mental Health
Canadian Institutes of Health Research (CIHR)

Completed

Fixed or Self-Titrated Dosages of Sativex on Cannabis Users

Cannabis Dependence

Canada
Hamilton Health Sciences Corporation
Sunnybrook Health Sciences Centre; Medtronic

Completed

Second Canadian Trial of Physiologic Pacing (CTOPP II): Pilot Trial

Pacemaker Dependence

Canada
Centre for Addiction and Mental Health

Terminated

Pharmacotherapy for Alcohol Dependence in Convicted Drinking Drivers

Alcohol Dependence

Canada
Centre for Addiction and Mental Health
Health Canada

Completed

Pilot Study of Text Message Brief Interventions for Problem Drinkers

Alcohol Dependence

Canada
Centre for Addiction and Mental Health
Health Canada

Completed

Helping Problem Drinkers on the Internet

Alcohol Dependence

Canada
Saskatchewan Health Authority - Regina Area
Gilead Sciences

Unknown

Switch to Genvoya Followed by HCV Therapy With Epclusa Followed by Simplification of HIV Therapy With Biktarvy in Patients With HIV-HCV Co-Infected Subjects on Opioid Substitution Therapy

Hepatitis C, Chronic | HIV/AIDS | Bone Diseases, Metabolic | Opioid Dependence | HIV-1-infection | HCV Coinfection | Buprenorphine Dependence | Methadone Dependence | Co-infection

Canada
York University
University of Manitoba

Completed

Testing the Efficacy of an Online Treatment Program for Heavy Cannabis Use

Marijuana Use | Marijuana Dependence

Canada
University of Pennsylvania
National Institute on Drug Abuse (NIDA)

Completed

Pharmacogenetics of Nicotine Addiction Treatment

Nicotine Addiction

United States, Canada
Centre hospitalier de l'Université de Montréal...

Recruiting

Joint Effort 2.0: a Mobile Application With University Students (JOINTEFFORT)

Cannabis | Cannabis Dependence | Cannabis Use | Cannabis Smoking | Cannabis Use, Unspecified

Canada
University of British Columbia
Provincial Health Services Authority

Withdrawn

Tobacco Retraining of Automatic Approach to Treat Individuals With Tobacco Dependence and Severe Concurrent Disorders.

Tobacco Retraining of Automatic Approach | Placebo Task

Canada
Centre hospitalier de l'Université de Montréal...
Pfizer

Completed

Desvenlafaxine in Opioid-Dependent Patients

Depression | Opioid Dependence | Methadone Treatment

Canada
Centre hospitalier de l'Université de Montréal...

Completed

Cannabidiol and Cocaine Craving/Dependence (CBD)

Substance Use Disorder | Cocaine Dependence | Withdrawal From Addictive Substance; Detoxification

Canada
Ottawa Hospital Research Institute

Unknown

E-Cigarette Inner City RCT

Substance Use | Mental Illness | Tobacco Dependence | COPD Asthma

Canada
Centre for Interdisciplinary Research in Rehabilitation...
McGill University; Université du Québec à Trois-Rivières; Université de Montréal

Completed

Transition in Care From Post-acute Services for the Elderly in Quebec (PAHP)

Rehabilitation | Older Adults | Physical Therapy | Functional Independence

Canada
Bayer

Active, not recruiting

A Study to Learn if Elinzanetant Affects the Ability to Drive and Brain Function in Healthy Women

Hot Flashes | Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men

Canada
Centre for Addiction and Mental Health

Completed

Using Non-invasive Brain Stimulation (tDCS) With Varenicline for Treating Tobacco Dependence

Smoking Cessation | Tobacco Smoking | Tobacco Use Disorder | Substance Use Disorders | Molecular Mechanisms of Pharmacological Action | Tobacco Dependence | Physiological Effects of Drugs

Canada
University of Calgary
Alberta Health services

Completed

Delivering Contingency Management in Outpatient Addiction Treatment (PRISE)

Contingency Management | Substance Use | Methamphetamine-dependence | Substance Use Disorders | Substance Abuse | Drug Use | Methamphetamine | Drug Abuse | Adults | Methamphetamine Abuse | Humans

Canada

Clinical Trials on Nicotine Dependence in Canada

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in South Korea

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Rare Diseases

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Dietary Supplements

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