Clinical Trials on Nicotine Dependence

Total 2217 results

Maastricht University Medical Center
Maastricht University

Completed

A Fmri Study on the Effects of a Conjugate Vaccine and Placebo on CNS Activation and Behavior Following a Nicotine Challenge (EPU057)

Smoking | Nicotine Dependency

Netherlands
University of California, San Francisco
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)

Withdrawn

Cigarette Harm Reduction With Electronic Cigarette Use (NIDA-SREC)

Cardiovascular Risk Factor | Nicotine Dependence | Nicotine Dependence, Cigarettes | Nicotine Withdrawal | Tobacco Toxicity

United States
Washington University School of Medicine
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

Helping Poor Smokers Quit

Smoking | Smoking Cessation | Tobacco Use | Tobacco Smoking | Tobacco Use Cessation | Nicotine Dependence | Tobacco Dependence | Smoking, Tobacco | Nicotine Use Disorder | Nicotine Dependence, Cigarettes | Smoking, Cigarette | Nicotine Dependence Tobacco Product | Tobacco; Use, Rehabilitation | Smoking (Tobacco) Addiction and other conditions

United States
University of Vermont
National Institute on Drug Abuse (NIDA)

Completed

Impact of Nicotine Messaging on Nicotine Beliefs and Tobacco Use Behavior

Nicotine Dependence, Cigarettes

United States
Freedom Laser, Inc.
NST Consultants, Inc.

Completed

Evaluation of LLLT/Music for Smoking Cessation

Nicotine Dependence, Cigarettes

United States
University of Vermont
National Institute of General Medical Sciences (NIGMS)

Completed

Improving Smoking Cessation in Socioeconomically-Disadvantaged Young Adults

Nicotine Dependence, Cigarettes

United States
Milton S. Hershey Medical Center

Completed

Penn State TXT2Quit Study

Nicotine Dependence, Cigarettes

United States
Brown University
National Institute on Drug Abuse (NIDA)

Completed

Impact of Nicotine Reduction on Adolescent Cigarette Use, Alternative Tobacco Use, and Harm From Tobacco (SIREN)

Nicotine Dependence, Cigarettes, Uncomplicated

United States
University of Oslo
Charles University, Czech Republic; The Research Council of Norway

Recruiting

Negotiating a Quit Date or Not in Online Interventions

Nicotine Dependence, Cigarettes

Czechia, Norway
University of Oslo
Charles University, Czech Republic; The Research Council of Norway

Recruiting

Online Lapse Management Intervention

Nicotine Dependence, Cigarettes

Norway, Czechia
Duke University
National Institute on Drug Abuse (NIDA)

Completed

The Role of Nicotine Dose and Route of Delivery in Affecting Adoption of E-cigarettes and Reducing Exposure to Toxic Combustion Products (ENDS-Switch)

Nicotine Dependence, Cigarettes

United States
Milton S. Hershey Medical Center

Terminated

Penn State TXT2STAYQUIT Study- a Texting Study to Help Hospitalized Smokers Stay Quit

Nicotine Dependence, Cigarettes

United States
Semmelweis University

Completed

Epidemiology and Acute Oral Effects Electronic Cigarette

Nicotine Dependence, Cigarettes
Centre for Addiction and Mental Health

Completed

A Dietary Supplement for Early Cigarette Withdrawal (CIGAR)

Nicotine Dependence, Cigarettes, With Withdrawal

Canada
University of Oslo
Charles University, Czech Republic; The Research Council of Norway

Recruiting

Comparing SMS and E-mail Reminders in an Online Smoking Cessation Intervention

Nicotine Dependence Tobacco Product

Norway, Czechia
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Active, not recruiting

The INITIATE Study: Initiating Nicotine Dependence Treatment for Smokers Admitted to Emergency Departments (INITIATE)

Nicotine Dependence, Cigarettes | Nicotine Withdrawal

Canada
Medical University of South Carolina
National Institute on Drug Abuse (NIDA)

Completed

A Trial of E-cigarettes in Current Cigarette Smokers

Smoking | Nicotine Dependence | Nicotine Dependence, Other Tobacco Product

United States
Semmelweis University

Completed

Acute Oral Effects of Heated Tobacco Products

Nicotine Dependence, Cigarettes

Hungary
Yale University

Completed

Flavors and E-cigarette Effects in Adolescent Smokers- STUDY 1

Nicotine Dependence, Other Tobacco Product

United States
Juul Labs, Inc.

Completed

Clinical Study Comparing 7 ENDS Products and 1 Combustible Cigarette Using 2 Delivery Methods.

Tobacco Use | Tobacco Smoking | Nicotine Dependence | Nicotine Dependence, Cigarettes

New Zealand
Duke University
National Institute on Drug Abuse (NIDA)

Recruiting

Neurobehavioral Mechanisms Linking Childhood Adversity to Increased Risk for Smoking

Nicotine Dependence, Cigarettes | Adverse Childhood Experiences

United States
Milton S. Hershey Medical Center

Completed

The Get Quit - Stay Quit Study (GQSQ)

Nicotine Dependent Cigarette Smoker

United States
Juul Labs, Inc.

Completed

Comparing the Pharmacokinetics of Nicotine Salt Based ENDS in Healthy Smokers

Tobacco Use | Tobacco Smoking | Nicotine Dependence | Nicotine Dependence, Cigarettes

New Zealand
Juul Labs, Inc.

Completed

United States Pre-Market Tobacco Application Pharmacokinetics (US-PMTA-PK)

Tobacco Use | Tobacco Smoking | Nicotine Dependence | Nicotine Dependence, Cigarettes

United States
Fred Hutchinson Cancer Center
National Institute on Drug Abuse (NIDA)

Completed

A Smartphone Application (ACT on Vaping) for Vaping Cessation in Young Adults

Nicotine Dependence | Nicotine Use Disorder | Nicotine Vaping | Vaping | Nicotine Addiction

United States
Indiana University
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Reactions to E-cigs and Alcohol

Alcohol Abuse | Nicotine Dependence Tobacco Product

United States
Rowan University
University of Kentucky

Recruiting

Re-Connect Application for Smoking Cessation

Smoking Cessation | Nicotine Dependence, Cigarettes | Acceptability of Health Care

United States
Juul Labs, Inc.
Rose Research Center, LLC

Completed

A Study to Characterize Puff Topography With Use of JUUL 5% Electronic Nicotine Delivery Systems (ENDS) in Adult Smokers

Tobacco Use | Tobacco Smoking | Nicotine Dependence, Other Tobacco Product

United States
American University of Beirut Medical Center
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)

Recruiting

Assess the Influence of Nicotine Flux and Nicotine Form on Subjective Effects Related to Dependency

Nicotine Dependence | Nicotine Vaping | Nicotine Addiction

Lebanon
Juul Labs, Inc.
Celerion

Completed

Identify Biomarkers of Tobacco Exposure and Nicotine Uptake From JUUL 5% in Adult Smokers (Diamond)

Tobacco Use | Smoking, Tobacco | Nicotine Dependence, Other Tobacco Product

United States
University of Virginia
National Institute on Drug Abuse (NIDA)

Completed

Medications Development for the Treatment of Cannabis Related Disorders (MTC)

Cannabis Dependence | Nicotine Dependence | Marijuana Dependence | Cannabis Abuse | Nicotine Withdrawal

United States
National Defense Medical Center, Taiwan

Recruiting

Effects of HRV Biofeedback on Autonomic Function and Nicotine Withdrawal Symptoms and Dependence in Smoking Cessation Adults

Heart Rate Variability, Biofeedback, Nicotine Dependence, Nicotine Withdrawal, Anxiety, Depression, Insomnia

Taiwan
Duke University
National Institutes of Health (NIH); National Center for Advancing Translational... and other collaborators

Terminated

Self-activation in Individuals With and Without Nicotine Dependence

Addiction Nicotine

United States
Yale University
National Institute on Drug Abuse (NIDA); US Department of Veterans Affairs

Completed

Treatment for Nicotine Addiction in Women

Nicotine Dependence

United States
National Institute on Drug Abuse (NIDA)
University of Maryland

Completed

Pilot Study of Transcranial Magnetic Stimulation (TMS) in Nicotine Addiction

Nicotine Dependence

United States
Medical University Innsbruck

Completed

Randomized Trial of Ultrashort Psychotherapy vs Sustained-Release Bupropion for Smoking Cessation

Substance Abuse | Nicotine Dependence | Tobacco Dependence | Substance Dependence

Austria
Medical University of South Carolina

Terminated

Accelerated rTMS for the Reduction of Nicotine Craving

Nicotine Dependence | Nicotine Use Disorder

United States
University of California, San Francisco
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Comparative Pharmacokinetics and Pharmacodynamics of Synthetic Nicotine

Nicotine Dependence | Nicotine Vaping

United States
University of Pennsylvania
National Institute on Drug Abuse (NIDA)

Completed

Progesterone and Brain Imaging Study

Nicotine Dependence | Nicotine Withdrawal

United States
University of Minnesota
National Institute on Drug Abuse (NIDA); Pfizer

Completed

Human Laboratory Study of Varenicline and Bupropion for Nicotine Dependence (ChanBan)

Nicotine Dependence | Nicotine Withdrawal

United States
National Institute on Drug Abuse (NIDA)

Completed

Studying Nicotine Addiction With Transcranial Magnetic Stimulation

Nicotine Dependence

United States
University of Cincinnati
National Institute on Drug Abuse (NIDA)

Completed

Smoking-Cessation and Stimulant Treatment (S-CAST) (S-CAST)

Nicotine Dependence | Cocaine Dependence | Methamphetamine Dependence

United States
University of Southern California

Recruiting

Nicotine and Pavlovian Bias

Nicotine Dependence | Nicotine Vaping

United States
Medical University of South Carolina

Completed

Translational Neuropsychopharmacology Research of Nicotine Addiction

Nicotine Dependence, Cigarettes

United States
Medical University of South Carolina
National Institute on Drug Abuse (NIDA)

Completed

Combined Pharmaco/Behavior Therapy in Adolescent Smokers

Nicotine Dependence | Nicotine Use Disorder

United States
Federal University of São Paulo

Completed

Studying the Effects of Administration of Polyunsaturated Fatty Acids (PUFAS) of Omega-3 Series in Nicotine Dependence

Nicotine Dependence | Tobacco Dependence

Brazil
Centre for Addiction and Mental Health
Canadian Institutes of Health Research (CIHR)

Completed

Use of Pharmacotherapy to Reduce Cue-responsiveness in Smokers

Nicotine Dependence | Tobacco Dependence

Canada
PredictWatch

Recruiting

Mobile Health for Problematic Behaviors and Substance Use

Addiction | Cannabis Dependence | Nicotine Dependence | Nicotine Addiction | Behavioral Addiction

Poland
University of Wisconsin, Madison

Completed

Stress Neuroadaptation in Tobacco Dependence

Nicotine Dependence

United States
New York State Psychiatric Institute

Terminated

Electroretinogram: a New Human Biomarker for Smoking Cessation Treatment

Smoking | Smoking Cessation | Tobacco Use | Tobacco Smoking | Tobacco Use Disorder | Nicotine Dependence | Cigarette Smoking | Tobacco Dependence | Nicotine Use Disorder | Smoking, Cigarette

United States

Clinical Trials on Nicotine Dependence

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Gambia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations