Clinical Trials on Niemann-Pick Type C Disease

Total 56974 results

Johns Hopkins University
AbbVie

Recruiting

Rapid HCV Treatment Access for Persons Who Use Drugs (RAPID-HCV)

Hepatitis C Virus Infection, Response to Therapy of

United States, Canada
Fehmi Tabak
Viral Hepatitis Society

Completed

Direct Acting Agents in Hepatitis C Patients (HEPCTURKEY)

Hepatitis C | Hepatitis C Relapse | Hepatitis C Recurrent

Turkey
Kaohsiung Veterans General Hospital.

Unknown

Effects of Metformin, Pegylated Interferon Alpha and Ribavirin for Chronic Hepatitis C With Insulin Resistance

Insulin Resistance | Chronic Hepatitis c

Taiwan
Pfizer

Completed

Safety and Immunogenicity Study of 3 Vaccinations With TICOVAC in 2 Dosages in Healthy Children Aged Between 6 Months and 3 Years

Encephalitis, Tick-borne

Austria
Pfizer

Completed

Dose-finding Study to Investigate the Safety and Immunogenicity of Two Vaccinations With FSME IMMUN NEW in Healthy Volunteers Aged 1 to 6 Years.

Tick-borne Encephalitis

Austria, Germany
Pfizer

Completed

Dose-finding Study to Investigate the Safety and Immunogenicity of Two Vaccinations With FSME IMMUN NEW in Healthy Volunteers Aged 6 to 16 Years.

Tick-borne Encephalitis

Germany
Pfizer

Completed

FSME IMMUN NEW Follow-up to Study 208 in Volunteers Aged 16 to 66 Years

Encephalitis, Tick-borne

Poland
Medical University of Vienna

Completed

Humoral and Cellular Immunity of Low and High-responders After Tick-borne Encephalitis Vaccination

Tick-borne Encephalitis

Austria
AbbVie

Completed

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Co-administration of ABT-493 and ABT-530 With and Without Ribavirin in Subjects With HCV Genotype 1, 4, 5, and 6 Infection

Chronic Hepatitis C | Hepatitis C Virus | HCV
Merck Sharp & Dohme LLC

Completed

Study of Efficacy and Safety of Grazoprevir (MK-5172)/Elbasvir (MK-8742) Combination Regimen for Treatment-Naïve Participants With Chronic Hepatitis C Virus Genotypes 1, 4, and 6 (MK-5172-060)

Chronic Hepatitis C Virus
Assiut University

Completed

Changes in Liver Fibrosis, Lipid Profile and Insulin Resistance in HCV Patients Who Received Antiviral Therapy

Chronic Hepatitis c

Egypt
Massachusetts General Hospital

Withdrawn

Single Patient Protocol for Donor HCV-positive to Recipient HCV-negative Kidney Transplant in a Patient at Risk for Loss of Dialysis Access

End Stage Renal Disease | Chronic Hepatitis c

United States
AbbVie (prior sponsor, Abbott)

Completed

A Study to Evaluate the Safety and Efficacy of ABT-450/Ritonavir/ABT-267; (ABT-267 Also Known as Ombitasvir) and ABT-333 (Also Known as Dasabuvir) Coadministered With Ribavirin (RBV) in Hepatitis C Virus (HCV) Genotype 1-infected Adults With Compensated Cirrhosis (TURQUOISE-II)

Compensated Cirrhosis | Chronic Hepatitis C Infection
University of North Carolina, Chapel Hill
National Institute of Nursing Research (NINR); Duke University

Completed

Study of Telemedicine Stress Management and Lifestyle Group Intervention for HCV Patients (VC-CBCS)

Chronic Hepatitis C

United States
Alios Biopharma Inc.

Completed

A Study to Evaluate the Safety, Pharmacokinetics and Efficacy of the Combination of AL-335, Odalasvir, and Simeprevir

Chronic Hepatitis C

New Zealand, Moldova, Republic of, Mauritius, United Kingdom
Stanford University
Gilead Sciences

Completed

Comparative Efficacy of Fixed-dose Combination Sofosbuvir + Ledipasvir, 8 vs. 12 Weeks in Chronic Hepatitis C Genotype 6

PT-NANBH

United States
Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical...

Completed

SR-BI and Antiviral Treatment Response in HCV

Chronic Hepatitis C
Stanford University
Yale University; Janssen Scientific Affairs, LLC

Withdrawn

Safety, Tolerability, and Efficacy of 24 Weeks Simeprevir+Sofosbuvir for Chronic Hepatitis C Genotype 1

PT-NANBH

United States
Cairo University

Completed

Association of Vitamin D Binding Protein Polymorphisms With Response to HCV Therapy

Chronic Hepatitis C
Hoffmann-La Roche

Completed

Safety, Tolerability, and Antiviral Activity of ANA598 in Patients With Genotype-1 Chronic HCV Infection

Chronic Hepatitis C

United States, Puerto Rico
Merck Sharp & Dohme LLC
Novartis Pharmaceuticals

Completed

Study to Evaluate Drug-drug Interaction Between Valopicitabine and Ribavirin

Chronic Hepatitis C

United States
Hospital Carlos III, Madrid

Unknown

Phase IV Study to Evaluate the Efficacy/Safety to Extend Treatment and High Dose of Ribavirin in co-Infected Patients (PERICO)

Chronic Hepatitis C

Spain
Alexion Pharmaceuticals
Achillion, a wholly owned subsidiary of Alexion

Terminated

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of ACH-0137171 in Participants With Chronic Hepatitis C Infection

HCV Infection

United States, Germany, Netherlands
Merck Sharp & Dohme LLC

Completed

Elbasvir (EBR)/Grazoprevir (GZR) in Pediatric Participants With Chronic Hepatitis C Infection (MK-5172-079)

HCV Infection

United States, Germany, Poland, Sweden
Hospital General de Mexico
AbbVie

Completed

Study to Determine the Hepatitis C Virus Infection Prevalence Among Patients Attended Primarily for Vasculitis

Vasculitis | Chronic Hepatitis c

Mexico
IBSA Farmaceutici Italia Srl
Derming SRL

Completed

Evaluation of Efficacy and Safety of HCC_45 for the Correction of Acne Scars of the Face

Acne Scars - Mixed Atrophic and Hypertrophic | Ice Pick Scars | Rolling Scars | Boxcar Scars

Italy
Center For Hepatitis C, Atlanta, GA

Active, not recruiting

Treatment of HCV-Infected Recent Injection Drug Users in U.S. Liver Clinics

Chronic Hepatitis C | People Who Inject Drugs

United States
Sunshine Lake Pharma Co., Ltd.

Completed

The Tolerability, Pharmacokinetics and Pharmacodynamics Study of HEC74647 in HCV-infected Subjects

Chronic Hepatitis C

China
Ain Shams University

Unknown

Metabolic Changes in Chronic HCV Patients Receiving DAAS (HCV DAAS)

Chronic Hepatitis C

Egypt
HaEmek Medical Center, Israel
AbbVie

Completed

Proof of Concept Study To Evaluate the Efficacy and Justification Of OBV/PTV/r and DSV In Adults With Chronic Hepatitis C Virus Genotype 2K/1B

HCV Coinfection

Israel
Gilead Sciences

Completed

Efficacy and Safety of Sofosbuvir Containing Regimens for the Treatment of Chronic HCV Infection in Participants With Chronic Genotype 1, 2, 3, or 6 HCV Infection

Chronic Hepatitis C

New Zealand
University of Modena and Reggio Emilia

Unknown

Efficacy Study to Evaluate the Effect of New Antiviral Drugs on HCV Infection.

Chronic Hepatitis, C Virus

Italy
Duke University
Novartis Pharmaceuticals

Completed

Randomized Controlled Trial in Liver Transplant Recipients Treated in Steroid Sparing Regimen

Chronic Hepatitis C | Organ Transplantation | Immunosuppression

United States
Human Genome Sciences Inc.
Novartis

Completed

Efficacy of Albumin Interferon Alfa-2b With Ribavirin Compared to Peg-IFN Alfa-2a With Ribavirin in IFN Naive Patients Geno2/3

Chronic Hepatitis C

Korea, Republic of, United States, Spain, Canada, France, Australia, Israel, Singapore, Thailand, Malaysia, Sweden, Belgium, Germany, Taiwan, Poland, Argentina, India, Puerto Rico, Brazil, Mexico, United Kingdom
Human Genome Sciences Inc.
Novartis

Completed

Efficacy of Albumin Interferon Alfa-2b With Ribavirin Compared With Peg-IFN Alfa-2a With Ribavirin in IFN Naive Patients

Chronic Hepatitis C

United States, Spain, Canada, France, Australia, Italy, Israel, Poland, United Kingdom, Germany, Czech Republic, Romania, Austria, India, Puerto Rico
AbbVie

Completed

A Study to Evaluate Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir in Treatment-Naïve Hepatitis C Virus Genotype 1b-Infected Adults (GARNET)

Hepatitis C Virus | Hepatitis C Infection
Cantonal Hospital Zenica

Completed

Thyroid Hormone Supplementation in Patients With Septic Shock

Septic Shock | Euthyroid Sick Syndromes

Bosnia and Herzegovina
Merck Sharp & Dohme LLC

Completed

Safety and Efficacy of Grazoprevir (MK-5172) + Elbasvir (MK-8742) in Participants With Chronic Hepatitis C and Chronic Kidney Disease (MK-5172-052) (C-SURFER)

Hepatitis C Virus
University of Maryland, Baltimore
Merck Sharp & Dohme LLC; Cairo University

Withdrawn

Clinical Trial to eLiminate HCV-infection in Treatment-naïve, Renally Impaired EgyptiAn Patients on Renal Dialysis, With Chronic Hepatitis C Genotype 4 (CLEAR-C4)

Hepatitis C Virus Infection, Response to Therapy of

Egypt
National Institute of Diabetes and Digestive and...
National Cancer Institute (NCI); National Institute of Allergy and Infectious... and other collaborators

Completed

Long Term Interferon for Patients Who Did Not Clear Hepatitis C Virus With Standard Treatment (HALT-C)

Fibrosis, Liver | Cirrhosis, Liver | Hepatic Cirrhosis | Chronic Hepatitis c

United States
AbbVie

Completed

A Study to Evaluate the Efficacy and Safety of ABT-493/ABT-530 in Subjects With Genotype 1 Infection

Chronic Hepatitis C | Hepatitis C Virus | HCV
Erasme University Hospital

Completed

Study of T Cell Phenotype Activation Pathway in Human Alcoholic Liver Disease

Alcoholic Liver Disease | Chronic Hepatitis C Virus

Belgium
Peter J. Ruane, M.D., Inc.
Gilead Sciences

Unknown

Study to Investigate the Efficacy and Safety of Ledipasvir/Sofosbuvir Fixed-Dose Combination for 12 Weeks in Subjects With Chronic Genotype 1 and 4 HCV Infection With Autoimmune Disease

Chronic Hepatitis C

United States
AbbVie

Completed

A Study to Evaluate the Safety and Efficacy of Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir With Ribavirin in Adults With Genotype 1 and Ombitasvir/Paritaprevir/Ritonavir With Ribavirin in Adults With Genotype 4 Chronic Hepatitis C Virus Infection and Decompensated Cirrhosis (TURQUOISE-CPB)

Decompensated Cirrhosis | Chronic Hepatitis C | Hepatitis C Virus
Universidade Federal do Rio de Janeiro
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.; Oswaldo Cruz... and other collaborators

Unknown

Autologous Bone Marrow Mononuclear Cells in Liver Cirrhosis (CELTHEP-02)

Liver Cirrhosis Due to Virus C Chronic Hepatitis

Brazil
Institute of Hematology & Blood Diseases Hospital

Withdrawn

Dasatinib Combined With Chemotherapy in Relapsed t(8;21) Acute Myeloid Leukemia With KIT D816 Mutation

Relapsed AML | T(8;21) | C-KIT Mutation

China
University Medical Centre Ljubljana
University of Ljubljana School of Medicine, Slovenia

Completed

Tick-borne Encephalitis and Possible Borrelial Serology

Lyme Disease | Tick Borne Encephalitis

Slovenia
Parc de Salut Mar

Completed

Impact of Antiviral Therapy on Gastroesophageal Varices.

Cirrhosis | Chronic Hepatitis C
Bader, Ted, M.D.

Terminated

HCV Treatment With Fluvastatin, Simvastatin to Improve Interferon Sensitivity

Chronic Hepatitis C

United States
Gilead Sciences

Terminated

Efficacy and Safety Study of GS-9450 Treatment for 6 Months in Patients With Chronic Hepatitis C Virus Infection

HCV Infection

United States, United Kingdom, Germany, Canada, Puerto Rico, Poland

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