Clinical Trials on Nocturnal Myoclonus Syndrome

Total 34022 results

Centre Hospitalier Universitaire, Amiens
University Hospital, Rouen; University Hospital, Lille

Recruiting

The Becoming of Children With Doose Syndrome (DOOSE)

Epileptic Syndromes | Learning Disabilities | Doose Syndrome

France
Universitaire Ziekenhuizen KU Leuven

Recruiting

Lymphoedema and Nocturia/Nocturnal Polyuria After Pelvic LND for Urogenital Cancer (UroLymph)

Nocturia | Urogenital Cancer | Lower Limb Lymphedema | Nocturnal Polyuria

Belgium
University College, London
University of North Carolina, Chapel Hill; NYU Grossman School of Medicine

Recruiting

Dentatorubral-pallidoluysian Atrophy Natural History and Biomarkers Study (DRPLA NHBS)

Dentatorubral-Pallidoluysian Atrophy

United States, United Kingdom
Tang-Du Hospital

Unknown

Effects and Mechanism of Pretreatment With Dexmedetomidine to Etomidate Induce Myoclonus

Myoclonus
Mansoura University Hospital

Completed

Electrophysiological Characteristics and Anatomical Differentiation of Epileptic and Non-epileptic Myoclonus.

Myoclonus | Evoked Potential

Egypt
Asan Medical Center

Completed

Donor Stem Cell Transplant After Busulfan, Fludarabine, Methylprednisolone, and Antithymocyte Globulin in Treating Patients With Bone Marrow Failure Syndrome

Myelodysplastic Syndromes | Leukemia | Nonmalignant Neoplasm | Paroxysmal Nocturnal Hemoglobinuria

Korea, Republic of
Alexion

Completed

ALXN1210 Versus Eculizumab in Adult Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Currently Treated With Eculizumab

Paroxysmal Nocturnal Hemoglobinuria (PNH)

United States, Korea, Republic of, Canada, France, Germany, Spain, United Kingdom, Japan, Australia, Italy, Netherlands
Ra Pharmaceuticals

Completed

Phase 2 Safety and Efficacy Study of Zilucoplan (RA101495) to Treat PNH Patients

Paroxysmal Nocturnal Hemoglobinuria (PNH)

United Kingdom, Australia, Canada, Denmark, Finland, Germany, Hungary, New Zealand
Alnylam Pharmaceuticals

Completed

A Phase 1/2 Study of an Investigational Drug, ALN-CC5, in Healthy Adult Volunteers and Patients With PNH

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Spain, United Kingdom
King's College Hospital NHS Trust

Completed

Study of Global Coagulation Tests in Patients With Paroxysmal Nocturnal Haemoglobinuria

Paroxysmal Nocturnal Haemoglobinuria

United Kingdom
Alexion Pharmaceuticals

Completed

Extension Study of Eculizumab in Patients With Transfusion Dependent Paroxysmal Nocturnal Hemoglobinuria (PNH)

Paroxysmal Hemoglobinuria, Nocturnal

United States, Australia, Belgium, Canada, Germany, Italy, Spain, Sweden, United Kingdom, France, Ireland, Netherlands
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Eculizumab to Treat Paroxysmal Nocturnal Hemoglobinuria

Paroxysmal Hemoglobinuria, Nocturnal

United States
Maastricht University Medical Center
Epilepsiecentrum Kempenhaeghe

Completed

The Rolandic Epilepsy/ESES/Landau-Kleffner Syndrome and Correlation With Language Impairment Study (REL)

Rolandic Epilepsy | Landau-Kleffner Syndrome | Nocturnal Frontal Lobe Epilepsy | Electrical Status Epilepticus During Slow Wave Sleep

Netherlands
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Haplo-identical Transplantation for Severe Aplastic Anemia, Hypo-plastic MDS and PNH Using Peripheral Blood Stem Cells and Post-transplant Cyclophosphamide for GVHD Prophylaxis

Paroxysmal Nocturnal Hemoglobinuria (PNH) | Severe Aplastic Anemia (SAA) | Hypo-Plastic Myelodysplastic Syndrome (MDS)

United States
Stichting Epilepsie Instellingen Nederland
Epilepsiefonds

Completed

Cardiac Arrhythmias in Dravet Syndrome

Epilepsy

Netherlands, Germany, United Kingdom
Apellis Pharmaceuticals, Inc.

Recruiting

A Study of Pegcetacoplan in Pediatric Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Paroxysmal Nocturnal Hemoglobinuria (PNH) | Paroxysmal Hemoglobinuria

Malaysia, United States, Czechia, France, Netherlands, Serbia, Spain, Thailand, United Kingdom
Tang-Du Hospital

Unknown

Effect of Pre-injection of Lidocaine on Myoclonus Induced by Induction With Etomidate in Elderly Patients During General Anesthesia

General Anesthesia

China
University of Aarhus
Ferring Pharmaceuticals

Completed

The Effect of Gender on Antidiuresis - Evaluated by Graded Low Dose Desmopressin Infusion

Nocturnal Enuresis | Nocturia | Gender Difference in V2 Receptor Function in Response to dDAVP Infusion

Denmark
Alexion

Completed

Paroxysmal Nocturnal Hemoglobinuria (PNH), Level of CD59 on Red and White Blood Cells in Bone Marrow Failure Syndromes (EXPLORE)

Hemoglobinuria
Jazz Pharmaceuticals

Recruiting

Assessment of Potential for Chronic Liver Injury in Participants Treated With Epidiolex (Cannabidiol) Oral Solution

Tuberous Sclerosis Complex | Dravet Syndrome | Lennox Gastaut Syndrome

United States
Cliniques universitaires Saint-Luc- Université...

Unknown

NOCTURNAL PAIN After Knee Arthroplasty : Incidence and Risk Factor: an Observational Study (NOCTURN-PAIN)

Pain, Postoperative | Knee Osteoarthritis | Prosthesis (Internal) Complications | Nocturnal Frequency

Belgium
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Trial of Allogeneic Stem Cell Transplants From HLA Compatible, Related and Unrelated Donors After a Myeloablative Preparative Regimen With Hyperfractionated TBI, Thiotepa and Fludarabine For Adult Patients With Lymphohematopoietic Disorders

Leukemia | Lymphoblastic Lymphoma | Myelodysplastic Syndrome | Paroxysmal Nocturnal Hemoglobinuria (PNH) | Allogeneic Stem Cell Transplant | Non-Hodgkins

United States
CARE Pharma Shanghai Ltd.

Completed

Natural History Study of Adult Patients With Paroxysmal Nocturnal Hemoglobinuria of High-risk Hemolysis in China

Paroxysmal Nocturnal Hemoglobinuria, Natural History Study

China
University Hospital, Strasbourg, France

Terminated

Predictive Factors of Obesity-hypoventilation Syndrome (OHS) Among Obese Subjects- ETUDE COHYPOB -

Obesity-hypoventilation Syndrome | Nocturnal Alveolar Hypoventilation

France
NYU Langone Health

Withdrawn

Turmeric as Treatment in Epilepsy

Epilepsy | Tuberous Sclerosis | Dravet Syndrome | Focal Seizures | Lennox-Gastaut Syndrome

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...

Completed

Study of High Dose Cyclophosphamide in Patients With Severe Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria

Aplastic Anemia | Paroxysmal Hemoglobinuria, Nocturnal

United States
University Ghent

Completed

Pharmacokinetics and Pharmacodynamics of Desmopressin Oral Lyophilisate Formulation in the Paediatric Population

Monosymptomatic Nocturnal Enuresis

Belgium
University of Pittsburgh
National Institute on Aging (NIA)

Completed

Impact of Behavioral Treatment of Insomnia on Nighttime Urine Production

Nocturnal Enuresis | Nocturia | Sleep Fragmentation | Poor Quality Sleep

United States
Longbio Pharma

Recruiting

A Study of Single and Multiple Doses of LP-005 in Healthy Adult Participants

Paroxysmal Nocturnal Hemoglobinuria (PNH)

China
BioCryst Pharmaceuticals

Terminated

BCX9930 for Treatment of PNH in Subjects With Inadequate Response to C5 Inhibitor Therapy (REDEEM-1)

Paroxysmal Nocturnal Hemoglobinuria (PNH)

United Kingdom, Hungary, France, Italy, Spain
AKARI Therapeutics
Radboud University Medical Center

Completed

Coversin in Paroxysmal Nocturnal Haemoglobinuria (PNH)

Paroxysmal Nocturnal Haemoglobinuria (PNH)

Netherlands
Shanghai Institute of Hypertension

Recruiting

Registry Study on "Control Nocturnal Hypertension to Reach the Target " (CONTROL-NHT)

Nocturnal Hypertension

China
University of Athens

Unknown

Evaluation of Nocturnal Hypertension and Correlation With Target-Organ Damage

Nocturnal Hypertension

Greece
Parasail, LLC

Available

Intravenous VAL-1221 Lafora Expanded Access Protocol (LEAP)

Lafora Disease
Ionis Pharmaceuticals, Inc.

Completed

Natural History and Functional Status Study of Patients With Lafora Disease

Lafora Disease

United States, Italy, Spain
ADARx Pharmaceuticals, Inc.
ADARx Australia Pty Ltd

Recruiting

Safety, Tolerability, PK and PD of ADX-038 in HV and Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients (PNH)

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Australia
NovelMed Therapeutics

Not yet recruiting

Study of NM8074 in Soliris-Treated Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)

PNH - Paroxysmal Nocturnal Hemoglobinuria
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of Twice Daily Oral Iptacopan (LNP023) in Adult PNH Patients Who Are Naive to Complement Inhibitor Therapy (APPOINT-PNH)

Paroxysmal Nocturnal Hemoglobinuria (PNH)

China, Germany, Singapore, Korea, Republic of, Italy, United Kingdom, Malaysia, France
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of Twice Daily Oral LNP023 in Adult PNH Patients With Residual Anemia Despite Anti-C5 Antibody Treatment (APPLY-PNH)

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Italy, Japan, Taiwan, Germany, France, United Kingdom, Spain, Korea, Republic of, Czechia, Brazil, Netherlands, United States
Hoffmann-La Roche
Chugai Pharmaceutical

Active, not recruiting

Study to Assess Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of Crovalimab in Healthy Volunteers and Participants With Paroxysmal Nocturnal Hemoglobinuria (COMPOSER)

Paroxysmal Hemoglobinuria, Nocturnal

France, Korea, Republic of, Italy, Japan, Germany, Hungary, Netherlands
Alexion Pharmaceuticals, Inc.
Achillion, a wholly owned subsidiary of Alexion

Completed

Study of Danicopan in Participants With Paroxysmal Nocturnal Hemoglobinuria With Inadequate Response to Eculizumab (PNH)

Paroxysmal Nocturnal Hemoglobinuria (PNH)

United Kingdom, United States, Italy
Regeneron Pharmaceuticals

Completed

Study to Evaluate the Efficacy and Safety of REGN3918 in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Hong Kong, Hungary, Korea, Republic of, Malaysia, United Kingdom
AO GENERIUM

Completed

Efficacy and Safety of Elizaria® vs. Soliris® in Patients With PNH

Paroxysmal Nocturnal Hemoglobinuria | Marchiafava-Micheli Syndrome | Paroxysmal Hemoglobinuria

Russian Federation
Alexion Pharmaceuticals, Inc.

Not yet recruiting

Study of Ultomiris® (Ravulizumab) Safety in Pregnancy

Pregnancy | Paroxysmal Nocturnal Hemoglobinuria (PNH) | Atypical Hemolytic Uremic Syndrome (aHUS) | Ultomiris-exposed Pregnant/ Postpartum | Generalized Myasthenia Gravis (gMG) | Neuromyelitis Optica Spectrum Disorder (NMOSD)
Kars State Hospital

Enrolling by invitation

Exercise and Dry Needling Treatment Combination in Nocturnal Calf Cramps

Myofascial Pain Syndrome | Nocturnal Leg Cramps

Turkey
National Institute of Neurological Disorders and...

Completed

Ketogenic Diet in Lafora Disease

Lafora Disease

United States
Jazz Pharmaceuticals

Recruiting

Assessment of Adjunctive Cannabidiol Oral Solution (GWP42003-P) in Children With Tuberous Sclerosis Complex (TSC), Dravet Syndrome (DS), or Lennox-Gastaut Syndrome (LGS) Who Experience Inadequately-controlled Seizures

Seizure in Participants With Tuberous Sclerosis Complex | Seizure in Participants With Dravet Syndrome | Seizure in Participants With Lennox-Gastaut Syndrome

United States
Inogen Inc.

Completed

Evaluation of POC Pulse-dose Demand Oxygen Delivery for Nocturnal Hypoxemia

Nocturnal Hypoxemia

United States
Wuhan Createrna Science and Technology Co., Ltd

Not yet recruiting

Study of Safety and Efficacy of MY008211A in in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Paroxysmal Nocturnal Hemoglobinuria (PNH)
BioCryst Pharmaceuticals

Terminated

BCX9930 for the Treatment of PNH in Subjects Not Receiving Other Complement Inhibitor Therapy (REDEEM-2)

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Malaysia, South Africa, Korea, Republic of

Clinical Trials on Nocturnal Myoclonus Syndrome

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