The Becoming of Children With Doose Syndrome

The Becoming of Children With Doose Syndrome

Sponsors

Lead Sponsor: Centre Hospitalier Universitaire, Amiens

Collaborator: University Hospital, Lille
University Hospital, Rouen

Source Centre Hospitalier Universitaire, Amiens
Brief Summary

Doose syndrome is a rare epileptic syndrome that can lead to learning difficulties and a poor quality of life. The goal of this study is to evaluate the evolution of epilepsy and its consequences on cognitive development and learning issues in children with Doose syndrome.

Detailed Description

Doose syndrome is a rare epileptic syndrome beginning between ages two and five, characterized by myoclonic-astatic seizures which can be associated with myoclonic seizures, astatic seizures, absences and generalized tonic-clonic seizures. These seizures can be difficult to treat effectively and may lead to learning difficulties. During this study, parents of children with Doose syndrome will receive a questionnaire regarding learning disabilities, quality of life and epilepsy of their children.

Overall Status Not yet recruiting
Start Date August 2019
Completion Date August 2021
Primary Completion Date August 2021
Study Type Observational
Primary Outcome
Measure Time Frame
disease effects on the learning ability of children with doose syndrome day of inclusion
Secondary Outcome
Measure Time Frame
Evolution of epilepsy in children with doose syndrome based on pathological symptoms day of inclusion
Enrollment 50
Condition
Intervention

Intervention Type: Other

Intervention Name: questionnaire

Description: questionnaire send to the parents

Eligibility

Sampling Method: Non-Probability Sample

Criteria:

Inclusion Criteria:

- children with doose syndrome diagnosed between ages 1 and 6

- normal development until onset of seizures

Exclusion Criteria:

- unconfirmed diagnoses

- abnormal diagnoses

- abnormal psychomotor development before onset of seizures

- cerebral MRI abnormalities

- other child epileptic syndromes

Gender: All

Minimum Age: 1 Year

Maximum Age: 6 Years

Healthy Volunteers: No

Overall Official
Overall Contact

Last Name: Patrick Berquin, Pr

Phone: (33)30322087670

Email: [email protected]

Verification Date

August 2019

Responsible Party

Type: Sponsor

Keywords
Has Expanded Access No
Condition Browse
Acronym DOOSE
Patient Data No
Study Design Info

Observational Model: Cohort

Time Perspective: Prospective

Source: ClinicalTrials.gov