Clinical Trials on Non-erosive Esophagitis in South Africa

Total 1356 results

Braintree Laboratories

Enrolling by invitation

A Study to Evaluate the Long-Term Safety of BLI5100 in Patients With Gastroesophageal Reflux Disease

Non-erosive Reflux Disease | Erosive Esophagitis

United States
Braintree Laboratories

Recruiting

A Study to Evaluate the Efficacy and Safety of BLI5100 in Patients With Erosive Esophagitis

Erosive Esophagitis

United States
Phathom Pharmaceuticals, Inc.

Completed

Efficacy and Safety of Vonoprazan Compared to Lansoprazole in Participants With Erosive Esophagitis

Erosive Esophagitis

United States, Poland, Bulgaria, United Kingdom, Czechia, Hungary
AstraZeneca

Completed

A Dose-finding Phase IIb Study With AZD0865 and Esomeprazole in GERD Patients With Erosive Esophagitis.

GERD With Erosive Esophagitis

Sweden, United States, France, Italy, United Kingdom, Germany, Denmark, Finland, Norway, Canada
AstraZeneca

Completed

A Dose-finding Phase IIb Study With AZD0865 and Esomeprazole in GERD Patients Without Erosive Esophagitis.

GERD Without Erosive Esophagitis

Sweden, United States, France, Italy, United Kingdom, Germany, Denmark, Finland, Norway, Canada
Takeda

Completed

Safety and Efficacy of Dexlansoprazole Delayed-Release Capsules for Healing of Erosive Esophagitis and Maintenance of Healed Erosive Esophagitis and Relief of Heartburn in Adolescents

Gastroesophageal Reflux Disease | Erosive Esophagitis

United States, Poland, Belgium, Portugal, Italy, Hungary, Mexico, Brazil
GlaxoSmithKline

Completed

Intravenous Mepolizumab In Children With Eosinophilic Esophagitis

Oesophagitis, Eosinophilic

United States, Canada, United Kingdom, Australia
Centre for the AIDS Programme of Research in South...
Columbia University

Completed

Promoting Engagement in the Drug Resistant TB/HIV Care Continuum in South Africa (PRAXIS)

Patient Non-compliance

South Africa
Virginia Commonwealth University
Medical University of South Carolina; Ochsner Health System

Withdrawn

Confocal Endomicroscopy for Non-Erosive Reflux Disease (CE NERD) (CE_NERD)

Dyspepsia | Gastroesophageal Reflux Disease | Non Erosive Reflux Disease

United States
University of Cape Town

Completed

the PrEsentation, Rationale and Impact of reperFUSION for Acute Coronary Syndromes in Cape Town and the Garden Route Health District - the PERFUSION Registry (PERFUSION)

Acute Coronary Syndrome | Unstable Angina | ST Elevated Myocardial Infarction | Non ST Elevation Myocardial Infarction

South Africa
Braintree Laboratories

Active, not recruiting

A Study to Evaluate the Efficacy and Safety of BLI5100 in Patients With Non-Erosive Reflux Disease

Non-erosive Reflux Disease

United States
National Cancer Institute (NCI)

Unknown

Combination Chemotherapy in Patients With Advanced or Recurrent Mycosis Fungoides

Lymphoma

South Africa
Boston University
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Completed

Non-Communicable Diseases and Antiretroviral Therapy Outcomes in the RapIT Study Population (RapIT-NCD)

Cardiovascular Diseases | Diabetes Mellitus, Type 2 | Antiretroviral Therapy, Highly Active

South Africa
Bio-Thera Solutions

Completed

A Comparative Study of BAT1706 and EU Avastin® in Patients With Advanced Non Squamous Non Small Cell Lung Cancer

Non-squamous Non-small Cell Lung Cancer

China, Mexico, South Africa, Turkey, Ukraine
University of Cape Town
Medtronic

Suspended

Left Cardiac Sympathetic Denervation for Cardiomyopathy Feasibility Pilot Study (LCSD)

Dilated Cardiomyopathy | Ischemic Cardiomyopathy | Non-ischemic Cardiomyopathy

South Africa
University of Pretoria
Nestlè Nutrition Institute Africa; South African Sugar Association

Completed

Nutrition Education Intervention in Adults With Type 2 Diabetes Mellitus in a Resource Poor Setting

Diabetes Mellitus, Type II [Non-insulin Dependent Type] [NIDDM Type] Uncontrolled

South Africa
Duke University
The Emmes Company, LLC

Recruiting

Pharmacokinetics of Antiretroviral Drugs in Lactating Women and Breastmilk Fed Infants Under 6 Months of Age in Botswana (BMS02)

HIV Infections | Lactating Women on Select DOI | Breastmilk Fed Infants of Mothers on Select DOI

South Africa
University of Cape Town

Completed

Hypertension And Surgery Study: Evaluating the Implementation of a Hypertension Guideline Protocol (HASS-2)

Hypertension | Metabolic Syndrome | Non-Compliance, Medication

South Africa
Takeda

Completed

Efficacy and Safety of Dexlansoprazole MR and Lansoprazole on Healing of Erosive Esophagitis

Esophagitis, Peptic | Esophagitis, Reflux

United States, Poland, Bulgaria, India, Canada, Peru, Russian Federation, Australia, New Zealand, Czech Republic, Slovakia, South Africa, Latvia, Lithuania, Colombia, Germany
Eupraxia Pharmaceuticals Inc.

Recruiting

A Trial to Evaluate EP-104IAR in Adults With Eosinophilic Esophagitis (EoE). (RESOLVE)

Eosinophilic Esophagitis

Australia, Canada, Netherlands
Takeda

Completed

Efficacy and Safety of Dexlansoprazole MR and Lansoprazole on Healing of Erosive Esophagitis

Esophagitis, Peptic | Esophagitis, Reflux

United States, Poland, Bulgaria, India, South Africa, Canada, Peru, New Zealand, Australia, Lithuania, Slovakia, Hungary, Latvia, Germany, Czech Republic
Phathom Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Efficacy and Safety of Vonoprazan Compared to Placebo in Participants With Symptomatic Non-Erosive Gastroesophageal Reflux Disease

Heartburn | Non-Erosive Gastro-Esophageal Reflux Disease

United States
European Organisation for Research and Treatment...

Completed

Temozolomide in Patients With Progressive or Recurrent Non-small Cell Lung Cancer

Lung Cancer

Italy, South Africa, United Kingdom, Netherlands, Poland
Shire

Completed

Dose-Ranging Study of Oral Viscous Budesonide in Pediatrics With Eosinophilic Esophagitis

Eosinophilic Esophagitis (EoE)

United States
Shire

Completed

OBS in Adolescent and Adults With EOE: A Phase II, Randomized, Double-Blind, Placebo Controlled, Study With an Open Label Extension

Eosinophilic Esophagitis (EoE)

United States
Takeda

Completed

Comparison of Dexlansoprazole MR to Placebo on the Ability to Maintain Healing in Subjects With Healed Erosive Esophagitis

Esophagitis, Peptic | Esophagitis, Reflux

United States
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of Arkansas; The Emmes Company, LLC; University of Stellenbosch

Withdrawn

Testing the Addition of Paclitaxel and Carboplatin Given After Standard Chemotherapy and Radiation for Cervical Cancer in HIV-positive Women

HIV Infection | Cervical Adenocarcinoma | Cervical Adenosquamous Carcinoma | Cervical Squamous Cell Carcinoma, Not Otherwise Specified | FIGO Stage IIB Cervix Carcinoma | FIGO Stage III Cervix Carcinoma | FIGO Stage IVA Cervix Carcinoma

South Africa, Zimbabwe
Takeda

Completed

Efficacy and Safety of Dexlansoprazole MR Compared to Placebo on Maintaining Healing in Subjects With Healed Erosive Esophagitis

Esophagitis, Peptic | Esophagitis, Reflux

United States, Canada, Czech Republic, Lithuania, Slovakia, Latvia, Estonia, Australia
Phathom Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Efficacy and Safety of Vonoprazan Compared to Placebo for Relief of Heartburn in Participants With Symptomatic Non-Erosive Gastroesophageal Reflux Disease (NERD)

Heartburn | Non-Erosive Gastro-Esophageal Reflux Disease

United States
Pfizer

Completed

Trial Of AG-013736, Cisplatin, And Gemcitabine For Patients With Squamous Non-Small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung (NSCLC)

Ukraine, Poland, Romania, South Africa
Shire
Takeda Development Center Americas, Inc.

Terminated

Continuation Study With Budesonide Oral Suspension (BOS) for Adolescent and Adult Participants With Eosinophilic Esophagitis (EoE)

Eosinophilic Esophagitis (EoE)

United States
Shire

Completed

An Extension Study to Evaluate Maintenance of Efficacy and Long-term Treatment Effect of Oral Budesonide Suspension (OBS) in Adults and Adolescents With Eosinophilic Esophagitis (EoE) (ORBIT2)

Eosinophilic Esophagitis (EoE)

United States
Takeda

Completed

Comparison of the Classical Healing Concept With the Complete Remission Concept After Treatment With Pantoprazole in Adult Patients With Erosive GERD (Gastroesophageal Reflux Disease) (BY1023/M3-342)

Gastroesophageal Reflux Disease

Germany, Poland, Brazil, South Africa
University of Bern
University of Alabama at Birmingham; University of Southern California; Louisiana... and other collaborators

Active, not recruiting

Genital Tract Infections, the Vaginal Microbiome and Gestational Age at Birth Among Pregnant Women in South Africa

HIV Infections | Premature Birth | Microbial Colonization | Pregnancy; Infection | Bacterial Vaginosis | Trichomonas Vaginitis | Neisseria Gonorrheae Infection | Chlamydia Trachomatis Infection | Mycoplasma Genitalium Infection | Genital Mycoplasma Infection | Vaginal Candida | Sexually Transmitted Infections... and other conditions

South Africa
Ironwood Pharmaceuticals, Inc.

Completed

Ph2a Study to Evaluate IW-3718 in Patients With Gastroesophageal Reflux Not Completely Responsive to Proton Pump Inhibitors

Gastroesophageal Reflux

United States
Shire

Completed

A Study in Adolescents and Adults With Eosinophilic Esophagitis (EoE) Measuring Histologic Response and Determine if Reduction in Dysphagia is Achieved

Eosinophilic Esophagitis (EoE)

United States
Regeneron Pharmaceuticals
Sanofi

Completed

Study to Determine the Efficacy and Safety of Dupilumab in Adult and Adolescent Patients With Eosinophilic Esophagitis (EoE)

Eosinophilic Esophagitis

United States, Australia, Belgium, Canada, France, Germany, Italy, Netherlands, Spain, Sweden, Switzerland, United Kingdom
Ellodi Pharmaceuticals, LP

Completed

Efficacy and Safety APT-1011 in Adult Subjects With Eosinophilic Esophagitis (EoE) (FLUTE-2) (FLUTE-2)

Eosinophilic Esophagitis

United States, Australia, Spain
Celgene

Active, not recruiting

A Study to Evaluate the Efficacy and Safety of CC-93538 in Adult and Adolescent Participants With Eosinophilic Esophagitis

Eosinophilic Esophagitis

Australia, United States, Argentina, Austria, Belgium, Canada, Germany, Israel, Italy, Japan, Poland, Portugal, Spain, Switzerland, United Kingdom
Celgene

Recruiting

Safety Study of CC-93538 in Adult and Adolescent Participants With Eosinophilic Esophagitis

Eosinophilic Esophagitis

United States, Belgium, Australia, Canada, Austria, Germany, Israel, Italy, Japan, Poland, Portugal, Spain, United Kingdom, Argentina, Switzerland
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Open Label Safety Study of Enteric-Coated Spheroid Suspension in Infants Aged Less Than 12 Months With Presumed Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux

Belgium, Italy, United States, Australia, Canada, France, Germany, Netherlands, Poland, South Africa, Switzerland
Allakos Inc.

Completed

A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Esophagitis (KRYPTOS)

Eosinophilic Esophagitis

United States, Australia, Netherlands
Pfizer
Arena is a wholly owned subsidiary of Pfizer

Completed

A Study to Assess the Safety and Efficacy of Oral Etrasimod in Adult Participants With Eosinophilic Esophagitis (VOYAGE)

Eosinophilic Esophagitis

United States, Spain, Switzerland, Australia, Belgium, Netherlands, Canada, Germany
Ception Therapeutics
Cephalon

Completed

Open-Label Extension Study of Reslizumab in Pediatric Subjects With Eosinophilic Esophagitis

Eosinophilic Esophagitis

United States, Canada
Takeda

Completed

Determination of the Minimal Clinically Important Difference After Treatment With Pantoprazole in Patients With Symptoms of Acid Reflux (Gastroesophageal Reflux Disease) (BY1023/M3-340)

Gastroesophageal Reflux

United States
MedImmune LLC

Completed

Subcutaneous Amifostine (Ethyol®) in the Prevention of Radiochemotherapy-Induced Esophagitis and Pneumonitis in Patients With Unresectable Non-Small Cell Lung Cancer

Esophagitis | Non-Small Cell Lung Carcinoma | Pneumonitis

United States
Ception Therapeutics

Completed

Efficacy and Safety Study of Reslizumab to Treat Eosinophilic Esophagitis in Subjects Aged 5 to 18 Years

Eosinophilic Esophagitis

United States, Canada
AstraZeneca
Amgen

Recruiting

Efficacy and Safety of Tezepelumab in Patients With Eosinophilic Esophagitis (CROSSING)

Eosinophilic Esophagitis

United States, Czechia, Spain, China, Australia, Italy, Belgium, Finland, Norway, Japan, Brazil, Austria, Greece, Canada, Netherlands, Sweden, Israel, Germany, Denmark, Slovakia, New Zealand, United Kingdom
Torax Medical Incorporated

Completed

LINX Reflux Management System in Subjects With GERD Who Have Previously Undergone a Laparoscopic Sleeve Gastrectomy (RELIEF)

Gastroesophageal Reflux Disease | GERD

United States
Takeda

Completed

Efficacy of Dexlansoprazole MR on Heartburn Control in Participants Previously Receiving Twice Daily Proton Pump Inhibitor Therapy

Gastroesophageal Reflux

United States

Clinical Trials on Non-erosive Esophagitis in South Africa

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