Clinical Trials on Non-malignant Diseases in United States

Total 148316 results

M.D. Anderson Cancer Center
Merck Sharp & Dohme LLC; BioMed Valley Discoveries, Inc

Active, not recruiting

Pembrolizumab With Intratumoral Injection of Clostridium Novyi-NT

Malignant Neoplasms of Female Genital Organs | Malignant Neoplasm of Breast | Malignant Neoplasms of Ill-defined Secondary and Unspecified Sites | Malignant Neoplasms of Lip Oral Cavity and Pharynx | Malignant Neoplasms of Independent (Primary) Multiple Sites | Malignant Neoplasms of Mesothelial... and other conditions

United States
Sameek Roychowdhury

Active, not recruiting

Ponatinib for Patients Whose Advanced Solid Tumor Cancer Has Activating Mutations Involving the Following Genes: FGFR1, FGFR2, FGFR3, FGFR4, RET, KIT.

Malignant Neoplasm

United States
S*BIO

Completed

A Phase 1 Study of SB1518 for the Treatment of Advanced Lymphoid Malignancies

Lymphoma, Malignant | Hodgkin's Lymphoma | B Cell Lymphoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Web-Based Family Outreach Program for Cancer Prevention in High-Risk Families

Malignant Neoplasm

United States
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Completed

Medical Physics Direct Patient Care for the Improvement of Patient Understanding of Care

Malignant Neoplasm

United States
OHSU Knight Cancer Institute
National Cancer Institute (NCI); Oregon Health and Science University

Completed

Video Distraction to Decrease Use of Sedation in Pediatric Participants During Radiation Therapy

Malignant Neoplasm

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Short-Term Fasting Before Chemotherapy in Treating Patients With Cancer

Malignant Neoplasm

United States
Emory University

Completed

Potential Use of Indocyanine Green as a Fluorescent Agent for Definition of Surgical Margins in Cancer

Malignant Neoplasm

United States
Indiana University

Completed

A Prospective Study of Thin Prep Versus Papanicolau in Suspected Malignant Lesions During Endoscopic Ultrasound (EUS)

Suspected Malignant Lesions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Neratinib and Everolimus, Palbociclib, or Trametinib in Treating Participants With Refractory and Advanced or Metastatic Solid Tumors With EGFR Mutation/Amplification, HER2 Mutation/Amplification, or HER3/4 Mutation or KRAS Mutation

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | KRAS Gene Mutation | Metastatic Malignant Solid Neoplasm | EGFR Gene Mutation | ERBB2 Gene Amplification | ERBB2 Gene Mutation | EGFR Gene Amplification | ERBB3 Gene Mutation | ERBB4 Gene Mutation

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Sapanisertib, Carboplatin, and Paclitaxel in Treating Patients With Recurrent or Refractory Malignant Solid Tumors

Refractory Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Terminated

Dual Energy Computed Tomography (CT) in Finding Bone Metastases in Patients With Cancer

Malignant Neoplasm | Metastatic Malignant Neoplasm to the Bone

United States
Eli Lilly and Company

Completed

A Study of LY3023414 in Participants With Advanced Cancer

Non-Hodgkin's Lymphoma | Metastatic Cancer | Malignant Mesothelioma | Metastatic Breast Cancer | Non-small Cell Lung Cancer | Advanced Cancer

United States, Puerto Rico, Italy
M.D. Anderson Cancer Center

Withdrawn

Robotic Bronchoscopy With Cone CT and Indocyanine Green to Aid Removal of Lung Lesions in Patients With Stage I Non-small Cell Lung Cancer or Lung Metastases, REPLACING Study

Lung Non-Small Cell Carcinoma | Stage I Lung Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Lung

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Combination of the Anti-cancer Drugs Copanlisib, Olaparib, and MEDI4736 (Durvalumab) in Patients With Advanced Solid Tumors With Selected Mutations

Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
National Cancer Institute (NCI)

Completed

S0509 - AZD2171 in Treating Patients With Malignant Pleural Mesothelioma That Cannot Be Removed By Surgery

Recurrent Malignant Mesothelioma | Advanced Malignant Mesothelioma | Epithelial Mesothelioma | Sarcomatous Mesothelioma

United States
University of Cincinnati

Completed

Chloroquine in Combination With Carboplatin/Gemcitabine in Advanced Solid Tumors

Solid Tumors | Malignant Neoplasm

United States
Seattle Children's Hospital

Suspended

Radiofrequency Ablation (RFA) Of Tumors Acquired In Childhood

Neoplasms, Benign | Neoplasms, Malignant

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing Copanlisib as Potentially Targeting Treatment in Cancers With PTEN Loss (MATCH - Subprotocol Z1G)

Malignant Solid Neoplasm

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

FLT-PET in Predicting Response to Chemotherapy in Patients With Advanced Malignancies

Malignant Neoplasm

United States
Fox Chase Cancer Center
National Cancer Institute (NCI)

Completed

Next Generation Sequence Target-Directed Therapy in Treating Patients With Cancer

Malignant Neoplasm

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); Conquer Cancer Foundation

Completed

Resistance Training Program and Cardiovascular Exercise in Increasing Muscle Mass in Adolescent and Young Adult Stem Cell Transplant Survivors

Malignant Neoplasm

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Terminated

Early Oral Supplementation in Improving Nutritional Status in Patients Undergoing Hematopoietic Stem Cell Transplant

Malignant Neoplasm

United States
UNC Lineberger Comprehensive Cancer Center

Recruiting

Measuring Changes in Body Composition and Physical Function in Patients With Childhood Cancers

Cancer | Malignant Neoplasm

United States
Indiana University School of Medicine
Alaunos Therapeutics

Terminated

Palifosfamide in Treating Patients With Recurrent Germ Cell Tumors

Stage IV Ovarian Germ Cell Tumor | Recurrent Ovarian Germ Cell Tumor | Extragonadal Seminoma | Recurrent Malignant Testicular Germ Cell Tumor | Stage IV Extragonadal Non-Seminomatous Germ Cell Tumor | Stage IV Extragonadal Seminoma | Adult Central Nervous System Germ Cell Tumor | Adult Teratoma | Malignant... and other conditions

United States
Providence Health & Services

Active, not recruiting

Hotspot TCR-T: A Phase I/Ib Study of Adoptively Transferred T-cell Receptor Gene-engineered T Cells (TCR-T)

Malignant Epithelial Neoplasms

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Perioperative Ostomy Self-Management Telehealth for Cancer Patients and Family Caregivers

Malignant Neoplasm

United States
M.D. Anderson Cancer Center
Loxo Oncology

Recruiting

Phase II Study of Pirtobrutinib With Venetoclax In Relapsed-Refractory MCL (Mantle Cell Lymphoma) Patients

Mantle Cell Lymphoma | Non Hodgkin Lymphoma | Hematologic Malignancy

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer

HIV Infection | Hepatocellular Carcinoma | Non-Hodgkin Lymphoma | Metastatic Lung Non-Small Cell Carcinoma | Metastatic Melanoma | Kaposi Sarcoma | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Locally Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Unresectable... and other conditions

United States
National Cancer Institute (NCI)

Recruiting

Testing the Combination of the Anticancer Drugs ZEN003694 and Binimetinib in Patients With Advanced/Metastatic or Unresectable Solid Tumors With RAS Alterations and Triple Negative Breast Cancer

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Triple-Negative Breast Carcinoma

United States
Pennington Biomedical Research Center

Recruiting

A Trial of a Multimodal Lifestyle Intervention to Optimize Survivorship After Cancer (Small Steps)

Neoplasm Malignant

United States
Jonsson Comprehensive Cancer Center

Active, not recruiting

Gene and Vaccine Therapy in Treating Patients With Advanced Malignancies

Malignant Neoplasm

United States
Jonsson Comprehensive Cancer Center

Terminated

Anti-tumor Immune Response in Patients With Cancer Undergoing Radiation Therapy

Malignant Neoplasm

United States
M.D. Anderson Cancer Center

Terminated

Indwelling Pleural Catheter With Either Doxycycline or Saline at Day 7 for Pleurodesis

Advanced Cancers | Malignant Pleural Effusions

United States
Mayo Clinic

Recruiting

Virtual Mindfulness and Weight Management to Mitigate Risk of Relapse and Improve Wellbeing in Cancer Survivors

Malignant Solid Neoplasm | Hematopoietic and Lymphoid System Neoplasm | Obesity-Related Malignant Neoplasm

United States
Vanderbilt-Ingram Cancer Center
National Institute of Nursing Research (NINR); Palliative Care Research Cooperative...

Completed

PCRC-Supported Legacy Intervention in Pediatric Palliative Care

Recurrent Malignant Neoplasm | Refractory Malignant Neoplasm | Care Giver

United States
New Mexico Cancer Care Alliance
National Cancer Institute (NCI)

Recruiting

Engagement of American Indians of Southwestern Tribal Nations in Cancer Genome Sequencing (PE-CGS)

Malignant Neoplasm

United States
University of Southern California
National Cancer Institute (NCI)

Terminated

Clinical Model in Evaluating Clinical, Psychosocial, and Health Economic Factors in Adolescent and Young Adult Patients With Cancer

Malignant Neoplasm

United States
Roswell Park Cancer Institute

Terminated

Impact of Early Mobility on Post-Surgery Recovery in Patients Undergoing Oncologic Surgeries

Malignant Neoplasm

United States
NatureWise Biotech & Medicals Corporation

Completed

A Safety and Pharmacokinetic Study of NBM-BMX Administered Orally to Patients With Advanced Cancer

Malignant Neoplasm

United States
Qilu Puget Sound Biotherapeutics (dba Sound Biologics)
Pharmaceutical Research Associates

Unknown

A Study of PSB205 in Subjects With Advanced Solid Tumors

Neoplasm Malignant

United States
Jonsson Comprehensive Cancer Center

Terminated

18F-Clofarabine PET/CT in Imaging Cancer Patients Before and After Interventions

Malignant Neoplasm

United States
M.D. Anderson Cancer Center
Gateway for Cancer Research; James B. and Lois R. Archer Charitable Foundation

Recruiting

Study of Aerosol Gemcitabine in Patients With Solid Tumors and Pulmonary Metastases

Malignant Neoplasms of Female Genital Organs | Malignant Neoplasms of Lip Oral Cavity and Pharynx | Melanoma and Other Malignant Neoplasms of Skin | Malignant Neoplasm of Bone and Articular Cartilage | Malignant Neoplasms of Independent (Primary) Multiple Sites | Malignant Neoplasm of Male... and other conditions

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

EHealth Mindful Movement and Breathing in Improving Outcomes in Participants Undergoing Gynecologic Surgery

Ovarian Carcinoma | Malignant Uterine Neoplasm | Malignant Female Reproductive System Neoplasm | Ovarian Neoplasm | Uterine Neoplasm | Female Reproductive System Neoplasm | Suspicious for Malignancy

United States
Incyte Corporation

Withdrawn

Itacitinib in Combination With Erlotinib in Non Small Cell Lung Cancer Patients With Epidermal Growth Factor Receptor (EGFR) Activating Mutations

Solid Tumors and Hematologic Malignancy | NSCLC (Non-small Cell Lung Carcinoma)

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Not yet recruiting

Improving Processes of Cancer Care Delivery at a Comprehensive Cancer Center

Metastatic Malignant Solid Neoplasm

United States
M.D. Anderson Cancer Center

Active, not recruiting

Technology-Enhanced Palliative Care for Advanced Cancer Patients

Advanced Malignant Solid Neoplasm

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

A Survey of Parent/Caregiver Practices on the Storage, Use, and Disposal of Opioids in a Comprehensive Cancer Center

Malignant Neoplasm | Caregiver

United States
Tianhong Li
National Cancer Institute (NCI); OncoImmune, Inc.

Terminated

CD24Fc for the Treatment of Immune Related Adverse Events in Patients With Advanced Solid Tumors, TIRAEC Study

Advanced Malignant Solid Neoplasm

United States
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Completed

Music in Reducing Distress in Participants With Cancer During Chemotherapy Treatment

Malignant Neoplasm | Caregiver

United States

Clinical Trials on Non-malignant Diseases in United States

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