Clinical Trials on Normal Immune Cell Function

Total 11266 results

Martin Angst

Completed

Evaluation of Immune Signaling Networks in Healthy Human Volunteers

Normal Immune Cell Function

United States
Novartis Pharmaceuticals

Completed

Evaluation of Hepatic Function Impairment on the Pharmacokinetics of LEE011

Normal Hepatic Function | Impaired Hepatic Function

United States
Novartis Pharmaceuticals

Completed

Effect of Hepatic Impairment on LDE225..

Normal Hepatic Function | Impaired Hepatic Function

Belgium, Germany, Israel, Bulgaria, United States
Englewood Hospital and Medical Center

Withdrawn

Neuropsychological Testing Using Mobile Devices

Inpatients With Normal Neurological Function

United States
Novartis Pharmaceuticals

Completed

Effect of Hepatic Impairment on LDK378 Pharmacokinetics

Normal Hepatic Function | Impaired Hepatic Function

United States
Shanghai Vinnerna Biosciences Co., Ltd.
Sponsor GmbH

Completed

A Study in Subjects With Liver Function Injury and Subjects With Normal Liver Function

Subjects With Liver Function Injury | Normal Liver Function Subject

China
Genta Incorporated

Completed

Pharmacokinetic Study of Genasense in Subjects With Normal Renal Function, Mildly Impaired Renal Function, and Moderately Impaired Renal Function

Normal Renal Function | Mildly Impaired Renal Function | Moderately Impaired Renal Function

United States
University of Florida
Kyowa Hakko Bio Co., Ltd.

Completed

Oral Glutathione Supplementation in Older Healthy Adults and Its Effect on the Number of Healthy Days Experienced During Four Months of Supplementation Compared to Placebo (GSH)

Improvement in Immune Cell Function in Elderly Humans

United States
National Cancer Institute (NCI)

Completed

In Vitro Study of Peripheral Blood Mononuclear Cell Function in Healthy Individuals and Patients

Cell Function

United States
University of Florida
Wakunaga Pharmaceutical Co., Ltd.

Completed

The Effect of Aged Garlic Extract Supplementation on Immune System

Improvement in Immune Cell Function in Healthy Humans

United States
Sanofi

Completed

A Study in Adults to Investigate the Impact of Mild, Moderate, and Severe Hepatic Impairment on Pharmacokinetics of Venglustat Compared to Participants With Normal Hepatic Function

Hepatic Function Abnormal

United States, Germany
Janssen Research & Development, LLC

Completed

A Study to Assess the Effects of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of Intranasally Administered Esketamine

Hepatic Impairment | Normal Hepatic Function

United States
Sanofi

Completed

A Pharmacokinetic and Tolerability Study of Fexinidazole in a Single Oral Dose in Adult Participants With Mild and Moderate Hepatic Impairment

Hepatic Function Abnormal

Bulgaria, France
Sanofi

Completed

Study to Assess the Plasma Concentration of Tolebrutinib Given as a Tablet to Adult Participants With Mild Hepatic Impairment Compared to Participants With Normal Hepatic Function

Hepatic Function Abnormal

United States, Belgium
Sanofi

Terminated

Pharmacokinetics of Amcenestrant in Female Hepatic Impaired Participants as Compared to Participants With Normal Hepatic Function

Hepatic Function Abnormal

Korea, Republic of, Germany
Geisinger Clinic

Completed

Comparison of 19g FNA and 19g FNB Needles for EUS-LB

Abnormal Liver Function

United States
Novartis Pharmaceuticals

Completed

Evaluation of Renal Function Impairment on the Pharmacokinetics of LEE011

Impaired Renal Function | Normal Renal Function

United States, Germany, Bulgaria, Czechia
Astellas Pharma Europe B.V.
FibroGen

Completed

A Phase 1 Study of Roxadustat in Subjects With Different Degrees of Renal Function

Impaired Renal Function | Normal Renal Function

Germany, United Kingdom
University of Saskatchewan
Canadian Institutes of Health Research (CIHR)

Completed

Synchrotron Imaging of Human Ovaries Ex Situ

Abnormal Female Reproductive Function

Canada
Stealth BioTherapeutics Inc.

Completed

A Phase 1 Study Investigating the Safety and Pharmacokinetics of Repeat-dose Intravenous Infusion of MTP-131 in Subjects With Impaired Renal Function

Normal and Impaired Renal Function

United States
GlycoMimetics Incorporated

Completed

A Study to Evaluate the Effect of IV Doses of Rivipansel in Subjects With Moderate Hepatic Impairment and in Healthy Subjects With Normal Hepatic Function

Moderate Hepatic Impairment | Normal Hepatic Function

United States
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

A Study to Investigate the Effect of Severely Diminished Liver Function on the Metabolism, Safety, and Tolerability of a Single Oral Dose of Enzalutamide in Men

Severe Hepatic Impairment | Normal Hepatic Function

Bulgaria
Genta Incorporated

Terminated

Pharmacokinetics of G3139 in Subjects With Advanced Melanoma, Including Those With Normal Hepatic Function and Those With Moderate Hepatic Impairment

Advanced Melanoma and Normal or Impaired | Hepatic Function
Toronto Metropolitan University
Mitacs

Recruiting

Adaptive Music Therapy for Psychosocial and Cognitive Functions of Older Adults (AMT)

Stress, Psychological | Loneliness | Emotion Regulation | Well Being | Executive Functions | Functional Abilities

Canada
Mitsubishi Tanabe Pharma America Inc.

Completed

PK Study in Subjects With Renal Impairment (Severe and if Required Mild & Moderate) Compared to Subjects With Normal Renal Function

Renal Impairment | Normal Renal Function

Germany
Hospital Ortopedico de Passo Fundo

Completed

Thoracic And Lumbar Burst Fracture: Correlation Between Structural Changes And Clinical Outcome Of Treatment

Traumatic Burst Fractures of the Thoracic or Lumbar Spine. | Normal Neurological Function

Brazil
RWTH Aachen University

Unknown

Impact of Acute Cerebral Diseases on the Autonomous Nervous System: Progression and Correlation to Therapy and Outcome (Pupillometry)

Cerebral Aneurysm | Pupillary Function, Abnormal

Germany
University of Reading
Danisco

Completed

A Study of a Prebiotic, a Probiotic and a Synbiotic Upon the Gut Microbiota and Immune Response of Healthy Volunteers (XOS)

Gut Microbiota | Immune Function | Bowel Function | Plasma Lipids

United Kingdom
International Centre for Diarrhoeal Disease Research...
University of Chicago; Marquette University; Mailman School of Public Health

Recruiting

1/2- Bangladesh Center for Global Environmental and Occupational Health- Bangladesh (GEOHealth-II)

Air Pollution | Cardiopulmonary Function | Immune Function | mHealth Intervention

Bangladesh
University Hospital Southampton NHS Foundation...
University of Southampton

Completed

Prebiotics and Immune Function in Middle Aged Humans

Immune Function

United Kingdom
University of Florida
Kyowa Hakko Bio Co., Ltd.

Withdrawn

GSH Supplementation on Cold/Flu Symptoms in Older Healthy Adults

Improvement in Immune Cell Function in Elderly Humans
Green Cross Wellbeing

Not yet recruiting

GCWB1176 Evaluates the Effectiveness and Safety of Immune Function

Immune Function

Korea, Republic of
Chonbuk National University Hospital

Completed

Evaluation of Efficacy and Safety of AGP on Immune Enhancement

Immune Function

Korea, Republic of
Yonsei University

Completed

Weissella Cibaria JW15 Consumption and NK Cell Activity

Immune Function
Centre Francois Baclesse

Terminated

Oral Therapies in Oncology: Cognitive Function and Compliance

Cancer | Cognitive Function | Compliance | Oral Therapies

France
Shanghai Cell Therapy Group Co.,Ltd
Shanghai Mengchao Cancer Hospital

Not yet recruiting

The Exploratory Study on the Nicotinamide Mononucleotide (Vital NAD ) to Promote the Rejuvenation of the Peripheral Blood Immune Cells of Adults.

Enhance Immune Function

China
University of Memphis
Mannatech

Completed

Comparison Study of Manapol and DaltonMax on Immune Function, Microbiome, and Related Variables in Men and Women

Microbiome | Immune Function

United States
Novartis Pharmaceuticals

Terminated

An Open-label, Dose Escalation Multi-center Study in Patients With Advanced Cancer to Determine the Infusion Rate Effect of ASA 404 With Paclitaxel Plus Carboplatin Regimen or Docetaxel on the Pharmacokietics of Free and Total ASA404

Metastatic Cancer With Impaired Renal Function | Metastatic Cancer With Normal Renal Function

Belgium
Oregon Health and Science University
National Heart, Lung, and Blood Institute (NHLBI); Office of Dietary Supplements...

Completed

Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function (VCSIP)

Second Hand Smoke | Pulmonary Function; Newborn, Abnormal | Infant Wheeze | In-utero Nicotine

United States
Foundation for Liver Research

Withdrawn

Pancreatic Enzyme Suppletion in Pancreatic Cancer (EPC)

Adenocarcinoma of the Pancreas | Normal Pancreatic Exocrine Function

Netherlands
Medical University of South Carolina

Completed

LYmphangiogenesis FacTors in Heart Failure States (LYFT-HF)

Heart Failure | Heart Failure With Reduced Ejection Fraction | Heart Failure With Normal Ejection Fraction

United States
Tufts University
Boston University; Boston Medical Center; Hebrew SeniorLife

Completed

Effect of Zinc Supplementation on Serum Zinc Level in Nursing Home Elderly

Disorder of Immune Function
Seoul National University Hospital

Unknown

Evaluation of PK and Biomarkers After UDCA Administrations to Subjects Who Are Overweight and Have Liver Problems

Overweight | Abnormal Liver Function Tests

Korea, Republic of
University of Reading
Danisco

Completed

The Effect of a Prebiotic, Probiotic and Synbiotic on the Gut Microbiota and Immune Response of Older Volunteers (GOS)

Gut Microbiota | Immune Function

United Kingdom
University of California, Davis
California Walnut Commission

Completed

Effects of the Consumption of California Walnuts on Cardiovascular Health

Immune Function | Cardiovascular Health

United States
University of Surrey
American Society of Hematology

Recruiting

Investigating the Role of Energy Balance Modification on Health Responses in Chronic Lymphocytic Leukaemia (HIT-CLL)

Frailty | Chronic Lymphocytic Leukemia | Muscle Function | Immune Function | Lipid Cell; Tumor

United Kingdom
University of Miami

Completed

A Personalized Reminder Information and Social Management System (PRISM)

Social Isolation | Social Support (Formal and Informal) | Well-being/Quality of Life

United States
Federico II University

Unknown

Surgical Stress and Colorectal Surgery (ESSIMIC)

Surgical Stress and Immune Function
Yakult Honsha Co., LTD
Japan Aerospace Exploration Agency

Active, not recruiting

Probiotics on Immune Function and Intestinal Microbiota in Astronauts Under Closed Microgravity Environment

Immune Function and Intestinal Microbiota

Japan
Tufts University
Tufts Medical Center; General Mills

Completed

The Addition of Whole Grains to the Diets of Adults: A Study of Digestive Health and Natural Defenses

Digestive Health and Immune Function

United States

Clinical Trials on Normal Immune Cell Function

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