Clinical Trials on Normal Drug Tolerance

Total 7643 results

Swedish Orphan Biovitrum
Parexel

Completed

A Study to Investigate the Potential Influence of Nitisinone on the Metabolism and the Transport of Other Drugs in Healthy Volunteers

Drug Drug Interaction

Germany
Dokuz Eylul University

Recruiting

The Effects of Exercise on Gait Characteristics, Balance, and Performance in Patients With Normal Pressure Hydrocephalus

NPH (Normal Pressure Hydrocephalus)

Turkey
University of Zurich

Active, not recruiting

Novel Parameters for the Prediction of Ventriculoperitoneal Shunting Efficacy in Patients With iNPH (iNPH)

Idiopathic Normal Pressure Hydrocephalus

Switzerland
Second Affiliated Hospital, School of Medicine,...
Westlake University

Unknown

Multi-omics Research of Idopathic Normal Pressure Hydrocephalus (iNPH)

Idiopathic Normal Pressure Hydrocephalus

China
Translational Research Center for Medical Innovation...
Johnson & Johnson; Codman & Shurtleff; Eisai Limited; Nihon Medi-Physics Co., Ltd. and other collaborators

Completed

Study to Evaluate Efficacy of Shunt Operation for Idiopathic Normal Pressure Hydrocephalus

Idiopathic Normal Pressure Hydrocephalus

Japan
Asceneuron S.A.

Recruiting

Drug-Drug Interaction of ASN51 With Fluvoxamine, Itraconazole and Paroxetine in Healthy Subjects

Drug Drug Interaction

Netherlands
Daewoong Pharmaceutical Co. LTD.

Recruiting

Drug-drug Interactions Between DWC202313 and DWC202314 in Healthy Subjects

Drug Drug Interaction

Korea, Republic of
Indiana University
National Institute of General Medical Sciences (NIGMS)

Recruiting

Interaction of CYP2B6 Genotype and Efavirenz With Methadone and Tizanidine PK

Drug-Drug Interaction

United States
VistaGen Therapeutics, Inc.
Parexel

Recruiting

AV-101 Alone and in Combination With Probenecid in Healthy Subjects

Drug Drug Interaction

United States
CMP Development, LLC

Completed

Drug-drug Interaction (DDI) Study of Spironolactone (Perpetrator) and Digoxin (Substrate Drug)

Drug Drug Interaction

India
Pyramid Biosciences

Completed

A Study of PBI-200 With Ritonavir or Cobicistat in Healthy Volunteers

Drug-drug Interaction

United States
Shanghai Pharmaceuticals Holding Co., Ltd

Completed

Drug-drug Interaction Study of SPH3127

Drug Drug Interaction

China
Blade Therapeutics

Completed

Drug-Drug Interaction (DDI) Study in Healthy Volunteers

Drug Drug Interaction

Australia
Antios Therapeutics, Inc

Completed

A Drug-Drug Interaction Study Between ATI-2173 and Midazolam or Clarithromycin in Healthy Subjects

Drug Drug Interaction

Canada
University Hospital, Basel, Switzerland

Completed

Inhibition Metamizole 2020

Drug-drug Interaction

Switzerland
Genfit

Completed

Study to Investigate the Potential Drug-Drug Interaction Between Elafibranor and Indomethacin

Drug-drug Interaction

France
Qure Healthcare, LLC
Aegis Sciences Corporation

Completed

DDI Effectiveness and Clinical Awareness (DECART)

Drug-Drug Interactions

United States
Santhera Pharmaceuticals

Completed

A Study to Assess the Potential for Pre-systemic Inhibition of CYP3A by Idebenone Using Midazolam as a Substrate

Drug-Drug Interaction

France
Indiana University

Withdrawn

System for Ocular Oxygen Measurement

Normal

United States
Fatih University

Unknown

Effect of Kangaroo Care on Heart Rate Variability

Immaturity | Oral Intolerance | Postnatal Adaptation

Turkey
Uppsala University Hospital
Uppsala University; Swedish Society for Medical Research

Recruiting

Acetazolamide Trial in Normal Pressure Hydrocephalus (DRAIN)

Idiopathic Normal Pressure Hydrocephalus (INPH)

Sweden
Johns Hopkins University
University of Utah; Integra LifeSciences Corporation

Completed

A Placebo-Controlled Effectiveness in INPH Shunting (PENS) Trial (PENS)

Idiopathic Normal Pressure Hydrocephalus (INPH)

United States, Canada, Sweden
Ohio State University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Active, not recruiting

The Renin-Angiotensin-Aldosterone System in Adiposity, Blood Pressure and Glucose in African Americans

Obesity | PreDiabetes | Blood Pressure | Impaired Glucose Tolerance

United States
Beni-Suef University

Completed

PRF in Management of Chronic Multiple Oral Ulcers

Oral Ulcer Due to Pemphius Vularis | Oral Ulcer Due to Benign Mucous Membrane Pemphioid | Oral Ulcer Due to Steven Johnson's Syndrome

Egypt
Abbott Nutrition

Terminated

Term Infants Fed a Partially Hydrolyzed Whey Protein-Based Formula

Gastro-Intestinal Tolerance

United States
Abbott Nutrition

Completed

Growth and Tolerance of Young Infants Fed Infant Formula

Growth and Tolerance

United States
Abbott Nutrition

Completed

Growth and Tolerance of Infants Fed Milk-Based Infant Formula

Gastro-Intestinal Tolerance

United States
Tel-Aviv Sourasky Medical Center

Completed

Age Related Changes in Cardiac Physiology as a Predictor of Exercise Tolerance

Aging | Exercise Tolerance

Israel
Abbott Nutrition

Completed

Evaluation of Carbohydrates Part 2

Gastro-Intestinal Tolerance

Canada
University of Texas Southwestern Medical Center

Terminated

Pharmacokinetics of Low Dose Ketamine Infusion

Sedation | Opioid Tolerance

United States
Abbott Nutrition

Completed

Growth and Tolerance of Infants Fed Infant Formulas

Growth and Tolerance

United States, Puerto Rico
University of Wisconsin, Madison

Completed

Study: Manometry With & Without Lidocaine

Normal

United States
Mayo Clinic

Terminated

Prognostic Value of Aβ Imaging in NPH Prior to Shunt Placement

Normal Pressure Hydrocephalus Patients

United States
Umeå University

Completed

Improved Analysis Methods for Infusion Tests

Idiopathic Normal Pressure Hydrocephalus

Sweden
Johns Hopkins University
National Institute of Neurological Disorders and Stroke (NINDS)

Recruiting

Efficacy in iNPH Shunting (PENS) Trial (PENS)

Idiopathic Normal Pressure Hydrocephalus (INPH)

United States, Canada, Sweden
University of Zurich
ETH Zurich

Completed

Walking Pattern Characteristics in Normal Pressure Hydrocephalus (NPH wearables)

Idiopathic Normal Pressure Hydrocephalus (INPH)

Switzerland
Erasmus Medical Center
UMC Utrecht; Medtronic; Albert Schweitzer Hospital; Isala; University Medical Center... and other collaborators

Completed

A Trial of High and Low Pressure Level Settings on a Programmable Ventriculoperitoneal Shunt Valve for Idiopathic Normal Pressure Hydrocephalus

Idiopathic Normal Pressure Hydrocephalus

Netherlands
Hospital Clinic of Barcelona

Unknown

ELIGIBLE (Efficacy of Left atrIal Appendage Closure After GastroIntestinal BLEeding) (ELIGIBLE)

Adverse Reaction to Drugs Affecting the Gastrointestinal System

Spain
Idorsia Pharmaceuticals Ltd.

Completed

Pharmacokinetics of Omeprazole and Midazolam When Co-administered With ACT-1014-6470

Healthy | Drug Drug Interaction

Czechia
Theravance Biopharma

Completed

Drug-Drug Interaction (DDI) Study for TD-9855

Drug Drug Interaction (DDI)

United States
Bristol-Myers Squibb

Completed

A Phase 1 Drug-drug Interaction Study in Healthy Volunteers (DDI)

Drug-drug Interaction Study

United States
University of Pennsylvania
Children's Hospital of Philadelphia

Recruiting

GLP-1 Agonist Therapy in Cystic Fibrosis-Related Glucose Intolerance

Diabetes | Cystic Fibrosis | Pancreatic Insufficiency | Abnormal Glucose Tolerance

United States
Muğla Sıtkı Koçman University

Unknown

Epidemiology of Polipharmacy and Potential Drug-Drug Interactions in Elderly Cardiac Outpatients (EPIC)

Polypharmacy | Drug-drug Interactions

Turkey
Jemincare

Completed

A DDI Study of JMKX000623 and Metformin Hydrochloride

Healthy | Drug-Drug Interaction

China
KBP Biosciences
Covance

Completed

Drug to Drug Interaction Study of KBP-5074 in Healthy Subjects

Healthy | Drug Drug Interaction

United States
Mayo Clinic

Not yet recruiting

Pharmacogenetic Panel to Prevent Adverse Drug Reactions in Daily Primary Care Practice: (PREPARE-Mayo)

Side Effect of Drug | Pharmacogenomic Drug Interaction | Drug Metabolism, Poor, CYP2D6-Related | Ineffective Drug Action | Drug Metabolism, Poor, CYP2C19-Related

United States
Komisarenko Institute of Endocrinology and Metobolism

Completed

Type 2 Diabetes Mellitus Prevention Ukraine (T2DPUA)

Type 2 Diabetes | Impaired Glucose Tolerance | Impaired Fasting Glucose

Ukraine
Marjukka Kolehmainen
Wageningen University; VTT Technical Research Centre, Finland

Completed

Dietary Modulation of Gene Expression and Metabolic Pathways in Glucose Metabolism (Sysdimet)

Obesity | Metabolic Syndrome | Impaired Glucose Tolerance | Impaired Fasting Glucose

Finland
University of Padova

Completed

Effect of Ingestion of Human, Cow, and Modified-cow Milk, on Glucose and Hormone Responses in Humans. (PROLAT)

Hormone | Insulin Tolerance | Aminoacidaemia
Weill Medical College of Cornell University
Agency for Healthcare Research and Quality (AHRQ)

Completed

Trial of an Intervention to Improve Metformin Persistence and Adherence (TreatMet)

Tolerance | Metformin Adverse Reaction

United States

Clinical Trials on Normal Drug Tolerance

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