Clinical Trials on Novel Mutation
Total 1723 results
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingLung Non-Small Cell Carcinoma | Stage III Lung Cancer AJCC v8 | Stage II Lung Cancer AJCC v8 | Stage IIA Lung Cancer AJCC v8 | Stage IIB Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Stage IIIC Lung Cancer AJCC v8 | EGFR Gene Mutation | Unresectable Lung Non-Small... and other conditionsUnited States
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Defense and Veterans Center for Integrative Pain...CompletedAnalgesia | Pain, Acute | Post Traumatic Stress Disorder | Amputation, Traumatic | Trauma, BrainUnited States
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Chinese University of Hong KongCompletedAmputation | Diabetic Foot UlcerChina
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University of Wisconsin, MadisonNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Enrolling by invitationDiabetic Foot | Amputation | Diabetic Ulcer of Left Foot | Diabetic Ulcer of Right FootUnited States
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Bolan Medical Complex Hospital Quetta PakistanCompletedDiabetic Foot | Amputation | Diabetic Foot Ulcer | Antibiotic Resistant StrainPakistan
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McMaster UniversityCanadian Institutes of Health Research (CIHR); Technology Evaluation in the... and other collaboratorsCompletedAntibiotic-Associated Diarrhea | Ventilator Associated Pneumonia (VAP) | Other Infections | C-Difficile | Duration of Mechanical Ventilation | Length of ICU Stay | Length of Hospital Stay | ICU and Hospital MortalityUnited States, Canada
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NYU Langone HealthAmerican Heart AssociationCompletedEmbolism and Thrombosis | Carotid Stenosis | Peripheral Vascular Disease | Peripheral Artery Disease | Aortic Aneurysm, Abdominal | Aortic Aneurysm | Aortic Aneurysm, Thoracic | Amputation, WoundUnited States
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Washington University School of MedicineAssociation of Frontotemporal Degeneration; Tau ConsortiumCompletedProgressive Supranuclear Palsy (PSP) | Corticobasal Degeneration (CBD) | Frontotemporal Dementia (FTD MAPT Mutation)United States
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Washington University School of MedicineCompletedMultiple Sclerosis | Amputation | Spinal Cord Injuries | Spina BifidaUnited States
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QuantumLeap Healthcare CollaborativeRecruitingSolid Tumor | Metastatic Cancer | Metastatic Breast Cancer | Triple Negative Breast Cancer | HER2-positive Breast Cancer | Solid Tumor, Adult | Solid Carcinoma | HER2-positive Metastatic Breast Cancer | Progesterone Receptor-positive Breast Cancer | HER2-negative Breast Cancer | Estrogen Receptor Positive... and other conditionsUnited States
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University of California, San DiegoNew York University; Heinrich-Heine University, Duesseldorf; Universität TübingenRecruitingGenetic Disease | Mitochondrial Encephalomyopathies | Neonatal Encephalopathy | Mutation | Hereditary Spastic Paraplegia | White Matter Disease | Spastic ParaplegiaUnited States
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Black Diamond Therapeutics, Inc.RecruitingNon-Small Cell Lung Cancer | NSCLC | Metastatic Lung Cancer | Metastatic Lung Non-Small Cell Carcinoma | EGF-R Positive Non-Small Cell Lung Cancer | Advanced Lung Carcinoma | EGFR-TKI Resistant Mutation | Advanced Non-Small Cell Squamous Lung Cancer | Epidermal Growth Factor Receptor C797S | Epidermal...United States
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Istituto Auxologico ItalianoRecruitingMultiple Sclerosis | Parkinson Disease | Amputation | Poststroke/CVA Hemiparesis | Knee ImpairmentItaly
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Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityCompletedDiabetic Foot | Amputation | Valve Heart Disease | Valve Disease, Aortic
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Fujian Cancer HospitalNot yet recruitingNon-small Cell Lung Cancer Confirmed by Histopathology or Cytology | The TNM (8th) Phase is IV | With EGFR Mutations | Meningeal Progression Occurred After Previous Platinum-containing Two-drug Chemotherapy and Third-generation EGFR-TKI Treatment | Male or Female | The Age of 18 Years Old or... and other conditions
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UNICANCERInstitut National de la Santé Et de la Recherche Médicale, France; Gustave... and other collaboratorsActive, not recruitingMutation | Hereditary Breast and Ovarian CancerFrance
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Tango Therapeutics, Inc.TerminatedBreast Cancer | Ovarian Cancer | Prostate Cancer | Pancreas Cancer | BRCA1 Mutation | BRCA-Mutated Ovarian Carcinoma | BRCA-Associated Breast Carcinoma | HRD Positive Advanced Ovarian CancerUnited States
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University of California, San FranciscoTerminatedNonfluent Aphasia, Progressive | Primary Tauopathies | Corticobasal Degeneration Syndrome | Frontotemporal Lobar Degeneration With Tau Inclusions | MAPT Mutation Carriers, Symptomatic | Traumatic Encephalopathy SyndromeUnited States
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National Cancer Institute (NCI)TerminatedUnspecified Adult Solid Tumor, Protocol Specific | Adenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage IV Pancreatic Cancer | Stage IV Breast Cancer | Stage IV Ovarian Epithelial Cancer | Stage IV Ovarian Germ Cell Tumor | Stage II Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB... and other conditionsUnited States
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Nuvectis Pharma, Inc.GOG Foundation; European Network of Gynaecological Oncological Trial Groups...RecruitingOvarian Cancer | Ovarian Endometrioid Adenocarcinoma | Advanced Solid Tumor | Ovarian Clear Cell Carcinoma | Ovarian Clear Cell Adenocarcinoma | Ovarian Clear Cell Tumor | Ovarian Endometrioid Tumor | ARID1A Gene MutationUnited States, United Kingdom
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University College Hospital GalwayRecruitingDiabetic Foot | Amputation | Wound Infection | Wound Complication | Wound Healing Delayed | Critical Limb-Threatening Ischaemia | Gangrene; LimbIreland
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Baylor College of MedicineElectrochemical Oxygen Concepts, Inc.RecruitingDiabetes | Diabetic Foot | Breast Cancer | Peripheral Arterial Disease | Surgical Wound | Amputation Wound | Incision WoundUnited States
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Forma Therapeutics, Inc.CompletedCohort 1a and 1b: Glioma (Advanced Gliomas and Glioblastoma Multiforme) | Cohort 2a and 2b: Hepatobiliary Tumors (Hepatocellular Carcinoma, Bile Duct Carcinoma, Intrahepatic Cholangiocarcinoma, Other Hepatobiliary Carcinomas) | Cohort 3a and 3b: Chondrosarcoma | Cohort 4a and 4b: Intrahepatic... and other conditionsUnited States, Korea, Republic of, Australia, United Kingdom, Spain, France
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Royal Marsden NHS Foundation TrustRecruitingLynch Syndrome | Familial Adenomatous Polyposis | Hereditary Diffuse Gastric Cancer | Peutz-Jeghers Syndrome | Cowden Syndrome | Li Fraumeni Syndrome | MutYH-associated Polyposis | SMAD4 Gene MutationUnited Kingdom
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Istituto Auxologico ItalianoRecruitingMultiple Sclerosis | Cerebral Palsy | Parkinson Disease | Amputation | Poststroke/CVA HemiparesisItaly
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Memorial Sloan Kettering Cancer CenterRecruitingSolid Tumor | Rhabdoid Tumor | Wilms Tumor | Nephroblastoma | Malignant Peripheral Nerve Sheath Tumors | MPNST | XPO1 Gene MutationUnited States
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Mohamed Abdel-RahmanRecruitingRenal Cell Carcinoma | Hepatocellular Carcinoma | Mesothelioma | Cholangiocarcinoma | Uveal Melanoma | Cutaneous Melanoma | Meningioma Atypical | BAP1 Gene MutationUnited States
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Hvidovre University HospitalRoskilde UniversityRecruitingLeg Ulcer | Venous Leg Ulcer | Foot Ulcer, Diabetic | Amputation Stump | Arterial Leg UlcerDenmark
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Joshua Mann, MPHNational Organization for Rare DisordersRecruitingVon Hippel-Lindau Disease | Hereditary Leiomyomatosis and Renal Cell Cancer | Birt-Hogg-Dube Syndrome | SDHB Gene MutationUnited States
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McGill UniversityNot yet recruitingCerebral Palsy | Amputation | Spinal Cord Injuries | Spina Bifida | Musculoskeletal Disorder | Juvenile ArthritisCanada
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Academisch Medisch Centrum - Universiteit van Amsterdam...ZonMw: The Netherlands Organisation for Health Research and DevelopmentRecruitingAmputation | Peripheral Vascular Disease | Diabetic Foot UlcerNetherlands
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Diabetica Solutions Inc.National Institutes of Health (NIH)CompletedDiabetes | Amputation | Neuropathy | Foot Deformity | UlcerationUnited States
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Apollomics Inc.RecruitingGastric Cancer | Pancreatic Cancer | NSCLC | Lung Cancer | Brain Tumor | Glioblastoma Multiforme | Advanced Cancer | Colon Cancer | Solid Tumors | Thyroid Cancer | Renal Cancer | Gastroesophageal Junction Adenocarcinoma | EGFR Gene Mutation | MET Amplification | HGF | MET Alteration | MET Fusion | Exon 14 SkippingUnited States, Spain, France, United Kingdom, Taiwan, Australia, Finland, Italy, Singapore, Hungary, Canada, Puerto Rico, Russian Federation
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Peloton Therapeutics, Inc., a subsidiary of Merck...Active, not recruitingVHL - Von Hippel-Lindau Syndrome | VHL Gene Mutation | VHL Syndrome | VHL Gene Inactivation | VHL-Associated Renal Cell Carcinoma | VHL-Associated Clear Cell Renal Cell CarcinomaUnited States, Denmark, United Kingdom, France
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McGill UniversityCanadian Institutes of Health Research (CIHR); McMaster University; Drexel UniversityNot yet recruitingCerebral Palsy | Amputation | Spinal Cord Injuries | Spina Bifida | Musculoskeletal Disorder | Juvenile ArthritisCanada
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Seagen Inc.Active, not recruitingUrologic Neoplasms | Uterine Cervical Neoplasms | Uterine Neoplasms | Carcinoma, Non-Small-Cell Lung | Biliary Tract Neoplasms | HER2 Mutations Breast NeoplasmsUnited States, United Kingdom, Spain, Korea, Republic of, Italy, Belgium, Germany, Japan, Netherlands, Poland
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Children's Hospital, Dziekanów Leśny, PolandCompletedThe Follow-up Duration Was 1-8 Years. | The Main Reasons Behind Visiting the Hospital Were Recurrent Urinary Tract Infection, | Urinary Urgencies, Pollakiuria, Difficulty in Initiating Micturition, Pain in Hypogastrium, | Night Wetting and Day Wetting, Menstruation's Disorders, Urolithiasis... and other conditionsPoland
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Abramson Cancer Center at Penn MedicineEnrolling by invitationOvarian Cancer | Genetic Predisposition to Disease | Breast Cancer Female | Hereditary Diseases | Gene Mutation-Related Cancer | Hereditary Breast and Ovarian Cancer | Hereditary Cancer SyndromeUnited States
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Peloton Therapeutics, Inc., a subsidiary of Merck...National Institutes of Health (NIH)CompletedClear Cell Renal Cell Carcinoma | Von Hippel-Lindau Disease | Clear Cell RCC | ccRCC | VHL Gene Mutation | VHL Syndrome | VHL Gene Inactivation | VHL | Von Hippel | Von Hippel's Disease | Von Hippel-Lindau Syndrome, Modifiers ofUnited States
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Biomea Fusion Inc.RecruitingColorectal Cancer | Pancreatic Cancer | NSCLC | Non Small Cell Lung Cancer | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | CRC | KRAS Mutation-Related Tumors | Relapsed Cancer | Refractory Cancer | Stage IV Non-small Cell Lung Cancer | Stage IV Colorectal Cancer | Stage III Non-small Cell Lung Cancer | Stage III NSCLC and other conditionsUnited States, Korea, Republic of
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Oslo University HospitalDiakonhjemmet HospitalRecruitingDiabetes Mellitus | Diabetic Foot | Diabetic Neuropathies | Amputation | Critical Limb Ischemia | Osteomyelitis | Claudication, Intermittent | Lower Extremity Ulcer | Diabetic AngiopathyNorway
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University of WashingtonEunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaboratorsCompletedMultiple Sclerosis | Low Back Pain | Chronic Pain | Muscular Dystrophies | Spinal Cord Injury | Other and Unspecified Amputation Stump ComplicationsUnited States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingBRCA1 Gene Mutation | BRCA2 Gene Mutation | Primary Peritoneal High Grade Serous Adenocarcinoma | Stage III Fallopian Tube Cancer AJCC v8 | Stage III Ovarian Cancer AJCC v8 | Stage III Primary Peritoneal Cancer AJCC v8 | Stage IIIA Fallopian Tube Cancer AJCC v8 | Stage IIIA Ovarian Cancer AJCC v8 | Stage... and other conditionsUnited States
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University of KansasCompletedStroke | Multiple Sclerosis | Cerebral Palsy | Arthritis | Muscular Dystrophy | Amputation | Spinal Cord Injury | Spina BifidaUnited States
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Academic and Community Cancer Research UnitedNational Cancer Institute (NCI)RecruitingBile Duct Adenocarcinoma | Fanconi Anemia Complementation Group Gene Mutation | Metastatic Bile Duct Carcinoma | PTEN Gene DeletionUnited States
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Memorial Sloan Kettering Cancer CenterRecruitingSolid Tumor | Neuroblastoma | Solid Tumor, Adult | Primary Brain Tumor | Solid Carcinoma | Low-grade Glioma | Central Nervous System Tumor | Refractory Cancer | CNS Tumor, Adult | CNS Tumors | NF1 | Plexiform Neurofibroma | CNS Tumor, Childhood | Optic Pathway Gliomas | MAP Kinase Family Gene MutationUnited States
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Children's Hospital of PhiladelphiaEli Lilly and Company; University of Pennsylvania; Takeda; National Institute of... and other collaboratorsRecruitingMucopolysaccharidoses | Leukoencephalopathies | Leukodystrophy | Adrenoleukodystrophy | Adrenomyeloneuropathy | X-linked Adrenoleukodystrophy | Gangliosidoses | Metachromatic Leukodystrophy | Krabbe Disease | Refsum Disease | Cadasil | Sjogren-Larsson Syndrome | Allan-Herndon-Dudley Syndrome | White Matter Disease | GM2... and other conditionsUnited States
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NeoTX Therapeutics Ltd.AstraZenecaActive, not recruitingMelanoma | Renal Cell Carcinoma | Hepatocellular Carcinoma | Pancreatic Adenocarcinoma | Ovarian Cancer | NSCLC | Prostate Cancer | Mesothelioma | Bladder Cancer | Triple Negative Breast Cancer | Endometrial Cancer | Colorectal Cancer Metastatic | Head and Neck Squamous Cell Carcinoma | Urothelial Cancer | Cervical Squamous... and other conditionsIsrael
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Khondrion BVNot yet recruitingMitochondrial Diseases | Mitochondrial DNA tRNALeu(UUR) m.3243A<G Mutation | Maternally Inherited Diabetes and Deafness (MIDD) | Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-like Episodes (MELAS)
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Epizyme, Inc.CompletedSynovial Sarcoma | Epithelioid Sarcoma | Renal Medullary Carcinoma | Malignant Rhabdoid Tumors (MRT) | Rhabdoid Tumors of the Kidney (RTK) | Atypical Teratoid Rhabdoid Tumors (ATRT) | Selected Tumors With Rhabdoid Features | INI1-negative Tumors | Malignant Rhabdoid Tumor of Ovary | Poorly Differentiated... and other conditionsFrance, United States, Australia, Taiwan, Belgium, United Kingdom, Canada, Germany, Italy