Clinical Trials on Obesity, Abdominal in United States

Total 5526 results

Dr Bob Ryder
Association of British Clinical Diabetologists

Completed

EndoBarrier in Obstructive Sleep Apnoea Study (End-OSA)

Obesity | Type 2 Diabetes | Obstructive Sleep Apnoea

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
Sheffield Hallam University

Completed

Lifestyle Intervention in Obstructive Sleep Apnoea

Obesity | Obstructive Sleep Apnoea

United Kingdom
ACADIA Pharmaceuticals Inc.

Recruiting

Study of Carbetocin Nasal Spray for the Treatment of Hyperphagia in Prader-Willi Syndrome

Hyperphagia in Prader-Willi Syndrome

United States, Canada, United Kingdom
Soleno Therapeutics, Inc.

Completed

Open-Label Extension Study of DCCR in PWS Followed by Double-Blind, Placebo-Controlled, Randomized Withdrawal Period

Prader-Willi Syndrome

United States, United Kingdom
Novartis Pharmaceuticals

Completed

Patupilone Versus Doxorubicin in Patients With Ovarian, Primary Fallopian, or Peritoneal Cancer

Peritoneal Neoplasms | Ovarian Cancer | Fallopian Tube Cancer

United States, Greece, Canada, Finland, Italy, Spain, United Kingdom, France, Denmark, South Africa, Australia, Poland
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Africa and Middle East Cardiovascular Epidemiological Study (ACE)

Smoking | Hypertension | Obesity | Diabetes Mellitus | Dyslipidemia

Egypt, Jordan, Lebanon, South Africa, United Arab Emirates, Saudi Arabia, Kuwait, Algeria, Cameroon, Ghana, Kenya, Nigeria, Senegal, Tunisia
University of Leicester
University of Oxford; University of Manchester

Recruiting

A Randomised, Controlled Trial of a Low-energy Diet for Improving Functional Status in Heart Failure With PRESERVED Ejection Fraction Preserved Ejection Fraction (AMEND)

Diabetes Mellitus, Type 2 | Heart Failure, Diastolic | Heart Failure With Preserved Ejection Fraction | Diabetes Mellitus Type 2 in Obese | Obesity Adult Onset

United Kingdom
Seattle Institute for Biomedical and Clinical Research
University of Illinois at Chicago; VA Puget Sound Health Care System

Completed

INtervention Study In overweiGHT Patients With COPD (INSIGHT COPD)

Obesity | Overweight | Pulmonary Disease, Chronic Obstructive | Weight Loss | Life Style

United States
Millendo Therapeutics SAS

Terminated

Effects of Livoletide (AZP-531) on Food-related Behaviors in Patients With Prader-Willi Syndrome (ZEPHYR)

Hyperphagia | Prader-Willi Syndrome

United States, Belgium, Spain, France, Italy, United Kingdom, Australia, Netherlands
Wake Forest University Health Sciences
National Institute of Mental Health (NIMH); University of Alabama at Birmingham

Completed

Risk Assessment of Long-Haul Truck Drivers

HIV Infections | Hypertension | Obesity | Diabetes Mellitus | Hepatitis B | Hepatitis C | Gonorrhea | Chlamydia Infections | Hyperlipidemia

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Vaccine Therapy and Cyclophosphamide in Treating Patients With Stage II-III Breast or Stage II-IV Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Recurrent Breast Carcinoma | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IIA Breast Cancer | Stage IIB Breast Cancer | Stage IIIC Breast Cancer | Stage IIA Fallopian Tube Cancer | Stage... and other conditions

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI); Sanofi Pasteur, a Sanofi Company

Completed

Sirolimus and Vaccine Therapy in Treating Patients With Stage II-IV Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cavity Cancer

Stage IV Ovarian Epithelial Cancer | Recurrent Ovarian Epithelial Cancer | Recurrent Primary Peritoneal Cavity Cancer | Stage IV Primary Peritoneal Cavity Cancer | Recurrent Fallopian Tube Cancer | Stage IIA Fallopian Tube Cancer | Stage IIB Fallopian Tube Cancer | Stage IIC Fallopian Tube Cancer | Stage... and other conditions

United States
St George's, University of London
SPD Development Company Limited

Suspended

Endocrine and Menstrual Disturbances in Women With Polycystic Ovary Syndrome (PCOS) (EMDPCOS)

Obesity | Polycystic Ovary Syndrome | Vitamin D Deficiency | Insulin Resistance

United Kingdom
Etan Orgel
Therapeutic Advances in Childhood Leukemia Consortium

Recruiting

Caloric Restriction and Activity to Reduce Chemoresistance in B-ALL (IDEAL2)

Obesity | B-cell Acute Lymphoblastic Leukemia

United States
Eli Lilly and Company

Active, not recruiting

A Study of Tirzepatide (LY3298176) in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF) and Obesity: The SUMMIT Trial (SUMMIT)

Obesity | Heart Failure With Preserved Ejection Fraction (HFpEF)

China, United States, Taiwan, Mexico, Brazil, Puerto Rico, Argentina, Israel, India, Russian Federation
Rashid Centre for Diabetes and Research

Completed

Effect of Vitamin D Supplementation on the Metabolic Control and Body Composition of Type 2 Diabetes Subjects in Ajman (UAE) (VDIS)

Obesity | Type 2 Diabetes Mellitus | Hypovitaminosis D

United Arab Emirates
Loughborough University
Nottingham University Hospitals NHS Trust; Nottingham Trent University

Completed

High-fat Overfeeding, Hepatokines and Appetite Regulation (OVEREAT)

Obesity | Insulin Resistance | Type2 Diabetes Mellitus | Non-Alcoholic Fatty Liver Disease

United Kingdom
Jesse Nodora
National Cancer Institute (NCI)

Terminated

COVID-19 Testing in Underserved and Vulnerable Populations

Coronary Artery Disease | Heart Failure | Obesity | Diabetes Mellitus, Type 2 | Cancer | Chronic Kidney Diseases | Sickle Cell Disease | COPD

United States
Ohio State University Comprehensive Cancer Center

Completed

Exercise and Diet Counseling Program in Improving Quality of Life in Stage I-III Breast Cancer Survivors

Obesity | Overweight | Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast... and other conditions

United States
Mayo Clinic
National Cancer Institute (NCI)

Active, not recruiting

Vaccine Therapy for Patients With Stage IIIC-IV Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cavity Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Ovarian Clear Cell Cystadenocarcinoma | Ovarian Endometrioid Adenocarcinoma | Ovarian Seromucinous Carcinoma | Ovarian Serous Cystadenocarcinoma | Fallopian Tube Transitional Cell Carcinoma | Ovarian... and other conditions

United States
University Hospital, Toulouse
European Society for Paediatric Endocrinology

Completed

PWS European Blood Bank for Infants and Controls From 0 to 48 Months

Prader-Willi Syndrome

Sweden, Belgium, France, Germany, Netherlands, United Kingdom
MEI Pharma, Inc.

Completed

OVATURE (OVArian TUmor REsponse) A Phase III Study of Weekly Carboplatin With and Without Phenoxodiol in Patients With Platinum-Resistant, Recurrent Epithelial Ovarian Cancer (OVATURE)

Peritoneal Neoplasms | Ovarian Cancer | Fallopian Tube Cancer

United States, Spain, Belgium, United Kingdom, Australia, Italy, Poland
King's College Hospital NHS Trust
University of Pennsylvania; Gilead Sciences; The Leeds Teaching Hospitals NHS... and other collaborators

Active, not recruiting

Genetic Determinants of Kidney Disease in People of African Ancestry With HIV (GEN-AFRICA)

Cardiovascular Diseases | Kidney Diseases | Obesity | Diabetes Mellitus | Genetic Predisposition to Disease | Kidney Injury | HIV Nephropathy

United Kingdom
London North West Healthcare NHS Trust

Active, not recruiting

Body Composition Manipulation in CoLorectal cancEr (BiCyCLE): Neuromuscular Electrical Stimulation (NMES) (BiCyCLE-NMES)

Colorectal Cancer | Rectal Cancer | Sarcopenia | Advanced Cancer | Colon Cancer | Colo-rectal Cancer | Sarcopenic Obesity | Recurrent Rectal Cancer

United Kingdom
Amgen

Active, not recruiting

Dose-ranging Study to Evaluate the Efficacy, Safety, and Tolerability of AMG 133 in Adult Subjects With Overweight or Obesity, With or Without Type 2 Diabetes Mellitus

Obesity | Overweight | Type 2 Diabetes Mellitus

United States, Czechia, Taiwan, Canada, Japan, Korea, Republic of, Germany, Hungary, Australia, Hong Kong, Spain, Poland
GlaxoSmithKline

Completed

Second-line Intravenous Treatment For Recurrent Platinum-Sensitive Ovarian, Fallopian, Or Peritoneal Cancer

Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Cancer | Neoplasms, Ovarian

United States, Canada
Eli Lilly and Company

Completed

A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes Who Have Obesity or Are Overweight (SURMOUNT-2)

Obesity | Overweight | Type 2 Diabetes

United States, Russian Federation, Taiwan, Argentina, Brazil, Japan, Puerto Rico, India
Novo Nordisk A/S

Completed

Effect and Safety of Liraglutide 3.0 mg in Subjects With Overweight or Obesity and Type 2 Diabetes Mellitus Treated With Basal Insulin (SCALE™ Insulin)

Obesity | Metabolism and Nutrition Disorder

United States, Israel, Italy, Mexico, Canada, Germany, Turkey
Novo Nordisk A/S

Completed

Effect of Liraglutide for Weight Management in Paediatric Subjects With Prader-Willi Syndrome

Obesity | Metabolism and Nutrition Disorder

France, United States, Turkey, Italy, Australia, New Zealand, Canada, Netherlands
Levo Therapeutics, Inc.

Completed

Phase 3 Study of Intranasal Carbetocin (LV-101) in Patients With Prader-Willi Syndrome (CARE-PWS)

Prader-Willi Syndrome

United States, Canada, Australia
University of Missouri-Columbia
National Library of Medicine (NLM)

Completed

Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Practice Workflow

Depression | HIV Infections | Hypertension | Obesity | Diabetes Mellitus | Back Pain | Urinary Incontinence | Irritable Bowel Syndrome | Insomnia | Asthma | Anxiety | Sinusitis | Shoulder Pain | Allergic Rhinitis | Urinary Tract Infection | Vaginitis | Bursitis | Hyperlipidemia | Esophageal Reflux | Benign Prostatic Hypertrophy | Osteoporosis... and other conditions

United States
Ohio State University Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Stress Reduction in Improving Quality of Life in Patients With Recurrent Gynecologic or Breast Cancer

Depression | Pain | Fatigue | Pseudomyxoma Peritonei | Peritoneal Carcinomatosis | Recurrent Endometrial Carcinoma | Anxiety Disorder | Ovarian Sarcoma | Recurrent Uterine Sarcoma | Recurrent Breast Cancer | Leydig Cell Tumor | Recurrent Ovarian Epithelial Cancer | Recurrent Primary Peritoneal Cavity Cancer | Ovarian... and other conditions

United States
Roswell Park Cancer Institute

Terminated

Exercise and Nutrition Education in Improving Physical Function and Quality of Life in Older Breast Cancer Survivors

Obesity | Overweight | Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast... and other conditions

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of an Anti-cancer Drug, Elimusertib (BAY 1895344) ATR Inhibitor, to the Chemotherapy Treatment (Gemcitabine) for Advanced Pancreatic and Ovarian Cancer, and Advanced Solid Tumors

Advanced Malignant Solid Neoplasm | Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma | Primary Peritoneal High Grade Serous Adenocarcinoma | Advanced Pancreatic Adenocarcinoma | Platinum-Resistant... and other conditions

United States
Novo Nordisk A/S

Completed

Effect of Liraglutide on Body Weight in Non-diabetic Obese Subjects or Overweight Subjects With Co-morbidities: SCALE™ - Obesity and Pre-diabetes

Obesity | Metabolism and Nutrition Disorder

United States, Poland, Israel, Italy, Mexico, Spain, Canada, Denmark, Finland, United Kingdom, France, Netherlands, Austria, Belgium, Argentina, Russian Federation, Serbia, Turkey, Switzerland, Germany, South Africa, Hungary, Hong Kong and more
University of Washington
GlaxoSmithKline

Recruiting

Niraparib and TSR-042 for the Treatment of BRCA-Mutated Unresectable or Metastatic Breast, Pancreas, Ovary, Fallopian Tube, or Primary Peritoneal Cancer

Anatomic Stage III Breast Cancer AJCC v8 | Prognostic Stage III Breast Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Metastatic Pancreatic Carcinoma | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Unresectable Pancreatic... and other conditions

United States
Goethe University
King's College London; Radboud University Medical Center; Heidelberg University; Hospital Vall d'Hebron

Completed

Prevention of Comorbid Depression and Obesity in Attention-deficit/ Hyperactivity Disorder (PROUD)

Depression | Obesity | Attention-Deficit / Hyperactivity Disorder

Germany, Netherlands, Spain, United Kingdom
James King
University of Nottingham; Nottingham University Hospitals NHS Trust; University...

Completed

Diabetes, Exercise and Liver Fat (DELIVER) ((DELIVER))

Liver Diseases | Glucose Metabolism Disorders | Obesity | Diabetes Mellitus | Type 2 Diabetes Mellitus | Fatty Liver | Insulin Resistance | Glucose Intolerance | Non-Alcoholic Fatty Liver Disease | Metabolic Disease

United Kingdom
National Cancer Institute (NCI)

Active, not recruiting

Epacadostat Before Surgery in Treating Patients With Newly Diagnosed Stage III-IV Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Stage III Fallopian Tube Cancer AJCC v7 | Stage III Ovarian Cancer AJCC v6 and v7 | Stage III Primary Peritoneal Cancer AJCC v7 | Stage IIIA Fallopian Tube Cancer AJCC v7 | Stage IIIA Ovarian Cancer AJCC v6 and v7 | Stage IIIA Primary Peritoneal Cancer AJCC v7 | Stage IIIB Fallopian Tube Cancer... and other conditions

United States
University of Nottingham

Recruiting

Nottingham Community Liver Biomarkers Cohort

Obesity | Type 2 Diabetes | Alcohol Use Disorder | Chronic Liver Disease | Persistently Elevated ALT

United Kingdom
QuantalX Neuroscience

Completed

DELPHI in Subjects at Risk for Stroke and Dementia

Smoking | Stroke | Hypertension | Sleep Disorder | Cognitive Impairment | Atrial Fibrillation | Transient Ischemic Attack | Dyslipidemias | Familial Alzheimer Disease | Diabete Mellitus | Overweight and Obesity | Cardiac Disease

United States, Israel
Baylor College of Medicine
University of California, San Diego; University of Alabama at Birmingham; Boston... and other collaborators

Completed

Sleep Abnormalities in Rare Genetic Disorders: AS, RTT, and PW (RDCRN)

Prader-Willi Syndrome | Rett Syndrome | Angelman Syndrome | Sleep Problems

United States
Anahuac University

Completed

Effect of a NSS to Reduce Complications in Patients With Covid-19 and Comorbidities in Stage III

Inflammation | Hypertension | Obesity | Diabetes Mellitus | Mortality | Overweight | COVID19 | Oxygen Saturation

Mexico
Queen Mary University of London

Completed

ESTEEM - Effect of Simple, Targeted Diet in Pregnant Women With Metabolic Risk Factors on Pregnancy Outcomes (ESTEEM)

Obesity | Insulin Resistance | Gestational Diabetes | High Blood Pressure | Pre-eclampsia | Stillbirth | Small for Gestational Age | Raised Lipids

United Kingdom
Eli Lilly and Company

Active, not recruiting

A Study of Orforglipron in Adult Participants With Obesity or Overweight and Type 2 Diabetes (ATTAIN-2)

Obesity | Overweight | Type 2 Diabetes

United States, China, Australia, India, Germany, Brazil, Argentina, Korea, Republic of, Czechia, Greece, Puerto Rico
Eli Lilly and Company

Recruiting

A Study of Daily Oral Orforglipron (LY3502970) Compared With Insulin Glargine in Participants With Type 2 Diabetes and Obesity or Overweight at Increased Cardiovascular Risk (ACHIEVE-4)

Cardiovascular Diseases | Obesity | Overweight | Type 2 Diabetes | Chronic Kidney Disease | Overweight or Obesity

United States, Italy, Spain, Korea, Republic of, India, Turkey, Austria, Puerto Rico, Romania, Brazil, Czechia, Germany, Mexico, Argentina, Greece, Slovakia
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Talazoparib and Radiation Therapy in Treating Patients With Locally Recurrent Gynecologic Cancers

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Recurrent Endometrial Carcinoma | Stage IV Uterine Corpus Cancer AJCC v8 | Stage IVA Uterine Corpus Cancer AJCC v8 | Stage IVB Uterine Corpus Cancer AJCC v8 | Recurrent Cervical Carcinoma | Malignant... and other conditions

United States
Novo Nordisk A/S

Active, not recruiting

A Research Study to See How Well CagriSema Helps People With Type 2 Diabetes and Excess Body Weight Lose Weight (REDEFINE 2)

Obesity | Overweight | Type 2 Diabetes Mellitus

United States, India, Poland, Malaysia, United Kingdom, Japan, Thailand, Germany, Austria, Canada, Hungary, Ireland, Puerto Rico
UNC Lineberger Comprehensive Cancer Center

Recruiting

Mobile Weight Loss Intervention for Adolescent and Young Adult Cancer Survivors (AYAConnect)

Sarcoma | Obesity | Leukemia | Cancer | Breast Cancer | Breast Neoplasms | Nasopharyngeal Carcinoma | Physical Activity | Hodgkin Disease | Hodgkin Lymphoma | Brain Tumor | Ewing Sarcoma | Non Hodgkin Lymphoma | Chondrosarcoma | Mental Health | Malignant Neoplasm | Myeloma | Central Nervous System Tumor | Germ Cell Tumor | Bone Tumor | Osteoid Sarcoma and other conditions

United States
Corcept Therapeutics
Gynecologic Oncology Group

Active, not recruiting

Relacorilant in Combination With Nab-Paclitaxel in Advanced, Platinum-Resistant, High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian-Tube Cancer

Fallopian Tube Neoplasms | Peritoneal Neoplasms | Ovarian Neoplasm

United States, Argentina, Australia, Belgium, Brazil, Canada, France, Hungary, Israel, Italy, Korea, Republic of, Poland, Spain, United Kingdom

Clinical Trials on Obesity, Abdominal in United States

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