Clinical Trials on Obstructive Chronic Bronchitis

Total 40207 results

Temple University
National Center for Complementary and Integrative Health (NCCIH); Quercegen...

Recruiting

Biological Effects of Quercetin in COPD Phase II (polyphenols)

Chronic Obstructive Pulmonary Disease | Emphysema | Chronic Bronchitis With Airway Obstruction

United States
Northumbria Healthcare NHS Foundation Trust
Newcastle-upon-Tyne Hospitals NHS Trust; National Institute for Health Research... and other collaborators

Completed

Mortality and Symptom Burden Post Hospitalisation With COPD (MoSHCOPD)

Pulmonary Disease, Chronic Obstructive | Emphysema | Chronic Bronchitis | Pulmonary Disease, Obstructive | Chronic Bronchitis With Airways Obstruction | Chronic Bronchitis With Acute Exacerbation

United Kingdom
Karolinska Institutet
The Swedish Research Council; Göteborg University; University of Bergen; University... and other collaborators

Active, not recruiting

Clinical & Systems Medicine Investigations of Smoking-related Chronic Obstructive Pulmonary Disease (COSMIC)

Smoking | Chronic Obstructive Pulmonary Disease | Emphysema | Chronic Bronchitis | Chronic Airways Obstruction

Sweden
Karolinska Institutet
Karolinska University Hospital; Lund University; Uppsala University; Göteborg University and other collaborators

Recruiting

BROnchoalveolar Investigations of Never-smokers With Chronic Obstruction From the Swedish CardioPulmonary bioImage Study (BRONCOSCAPIS)

Chronic Obstructive Pulmonary Disease | Emphysema | Airway Obstruction | Chronic Bronchitis | Smoking, Tobacco | Gender

Sweden
Villa Pineta Hospital

Unknown

Efficacy of Vakum Technology in Patients With Chronic Hypersecretion

Chronic Obstructive Pulmonary Disease | Chronic Bronchitis/Bronchiectasis

Italy
Parc de Salut Mar

Completed

Respiratory Therapy in COPD Exacerbations (TRESEPOCAS)

Obstructive Chronic Bronchitis With Acute Exacerbation

Spain
AstraZeneca

Completed

A 4 Week Study to Investigate the Safety and Tolerability of AZD5069 in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) (CIRRUS)

Scientific Terminology Chronic Obstructive Pulmonary Disease (COPD) | Laymen Terminology Chronic Bronchitis and Emphysema

Bulgaria, Germany, Hungary, Ukraine
Sheba Medical Center

Unknown

A Comparison Study of Two Respiratory Physical Therapy Methods and Standard Medical Treatment for Treating COPD Patients During Acute Exacerbation

Chronic Obstructive Pulmonary Disease | Chronic Bronchitis
Felix JF Herth

Unknown

Acute Dyspnea After Use of Non-invasive Ventilation in COPD and Emphysema (Deventilation Syndrome)

Obstructive Chronic Bronchitis
Johns Hopkins University
Patient-Centered Outcomes Research Institute; University of Illinois at Chicago

Recruiting

Roflumilast or Azithromycin to Prevent COPD Exacerbations (RELIANCE) (RELIANCE)

Chronic Bronchitis | Chronic Obstructive Pulmonary Disease Severe

United States
Lee's Pharmaceutical Limited

Unknown

A Multi-center, Randomized, Double-blind, Double-dummy Clinical Study to Evaluate the Safety and Efficacy of Prulifloxacin Film-coated Tablet for the Treatment of Acute Exacerbations of Chronic Bronchitis With Levofloxacin Hydrochloride Tablet as Active Control

Acute Exacerbations of Chronic Bronchitis

China
ThomasTruncale
Boehringer Ingelheim

Completed

The Effects of Tiotropium on the Cough Reflex in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease | Chronic Bronchitis

United States
Center for Veterans Research and Education

Unknown

N-Acetylcysteine for Patients With COPD and ChronicBronchitis

Chronic Obstructive Pulmonary Disease | Chronic Bronchitis

United States
Adams Respiratory Therapeutics

Completed

Phase 2 Study - Erdosteine in Patients With CB/COPD

Chronic Obstructive Pulmonary Disease | Chronic Bronchitis

United States
Chiesi Farmaceutici S.p.A.

Recruiting

A 52-week, Placebo-controlled Study to Evaluate the Efficacy and Safety of 2 Doses of CHF6001 DPI (Tanimilast), as add-on to Maintenance Triple Therapy in Subjects With COPD and Chronic Bronchitis (PILASTER) (PILASTER)

Chronic Obstructive Pulmonary Disease

Bulgaria, United States, Albania, Argentina, Australia, Austria, Bosnia and Herzegovina, Chile, China, Czechia, Georgia, Germany, Greece, Hungary, Israel, Italy, Mexico, Netherlands, New Zealand, North Macedonia, Poland, Romania, Russian... and more
University of North Carolina, Chapel Hill
Johns Hopkins University; National Heart, Lung, and Blood Institute (NHLBI); University... and other collaborators

Active, not recruiting

Study of COPD Subgroups and Biomarkers (SPIROMICS)

Chronic Obstructive Pulmonary Disease | Emphysema | COPD | Chronic Bronchitis

United States
University of Aarhus
Aarhus University Hospital

Completed

Mindfulness-based Cognitive Therapy for Chronic Obstructive Pulmonary Disease

Emphysema | Chronic Obstructive Pulmonary Disease (COPD) | Chronic Bronchitis | Chronic Obstructive Lung Disease | Chronic Obstructive Airway Disease

Denmark
Zhong Wang

Not yet recruiting

Effect of Zhuli Capsule on Phlegm-heat Syndrome (Tan-re Zheng)

Chronic Obstructive Pulmonary Disease | Chronic Bronchitis

China
Royal Brompton & Harefield NHS Foundation Trust

Recruiting

Studying the Airway Microenvironment in Patients Undergoing Surgical and Bronchoscopic Interventions for COPD (COPD-ENVIRON)

Chronic Obstructive Pulmonary Disease | Emphysema | Chronic Bronchitis

United Kingdom
Imperial College London
Royal Brompton & Harefield NHS Foundation Trust

Withdrawn

Macrophages in Smokers' Lung

Chronic Obstructive Pulmonary Disease | Emphysema | Chronic Bronchitis

United Kingdom
Chiesi Farmaceutici S.p.A.

Recruiting

A 52-week, Placebo- and Active- Controlled (Roflumilast, Daliresp® 500µg) Study to Evaluate the Efficacy and Safety of Two Doses of CHF6001 DPI (Tanimilast) as add-on to Maintenance Triple Therapy in Subjects With COPD and Chronic Bronchitis. (PILLAR) (PILLAR)

Chronic Obstructive Pulmonary Disease

Bulgaria, United States, Argentina, Austria, Bosnia and Herzegovina, Chile, Croatia, Czechia, Estonia, Germany, Greece, Hungary, Israel, Latvia, Mexico, Netherlands, New Zealand, North Macedonia, Poland, Romania, Russian Federation and more
Imperial College London

Completed

Macrophage Phagocytosis in COPD

Chronic Obstructive Pulmonary Disease | Emphysema | Chronic Bronchitis

United Kingdom
COPD Foundation
Kaiser Foundation Hospitals, Center for Health Research

Recruiting

COPD Patient-Powered Research Network (COPD PPRN)

Emphysema | Chronic Bronchitis | Chronic Obstructive Lung Disease | Chronic Obstructive Pulmonary Disorder

United States
Hanlim Pharm. Co., Ltd.

Completed

A Multicenter, Randomized, Double-blind, Parallel Group Study to Determine the Optimal Dose of HL301 After 7 Days Oral Administration in Acute Bronchitis or Acute Exacerbations of Chronic Bronchitis Patients (HL301: Mixed Extract of Rehmannia Glutinosa, Schisandra and so on) (HL301)

Acute Exacerbations of Chronic Bronchitis | Acute Bronchitis

Korea, Republic of
Duke University
Boehringer Ingelheim

Terminated

The Relationship Between GOLD Risk Group and Clinical Outcomes in a Community-based COPD Cohort

Emphysema | Chronic Obstructive Pulmonary Disease (COPD) | Chronic Bronchitis

United States
Sunovion

Completed

Determine the Safety and Efficacy of (R,R)-Formoterol in the Treatment of Subjects With COPD

Chronic Obstructive Pulmonary Disease | Emphysema | Chronic Bronchitis

United States
Sunovion

Completed

To Evaluate the Long-term Safety of (R,R)-Formoterol in Subjects With COPD

Chronic Obstructive Pulmonary Disease | Emphysema | Chronic Bronchitis

United States
University of Alabama at Birmingham
National Heart, Lung, and Blood Institute (NHLBI); Vertex Pharmaceuticals Incorporated

Completed

The Topic Trial - Study to Determine the Safety and Efficacy of Ivacaftor

Chronic Obstructive Pulmonary Disease | Chronic Bronchitis

United States
AstraZeneca

Completed

A Phase II, Randomized, Double-blind, Placebo-controlled Study to Assess MEDI3506 in Participants With COPD and Chronic Bronchitis (FRONTIER-4)

Chronic Obstructive Pulmonary Disease (COPD) | Chronic Bronchitis

United States, Canada, Denmark, Spain, United Kingdom, Taiwan, New Zealand, Australia, Germany, Israel, South Africa, Czechia, Hungary, Poland, Netherlands
Northern Care Alliance NHS Foundation Trust

Completed

Activity Monitor Use in COPD Patients Undergoing Rehabilitation

Chronic Obstructive Pulmonary Disease | Emphysema | COPD | Chronic Bronchitis

United Kingdom
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Completed

Mucus Dehydration and Evolution of Chronic Obstructive Pulmonary Disease (COPD) Lung Disease

Chronic Obstructive Pulmonary Disease | Chronic Bronchitis

United States
Neutec Ar-Ge San ve Tic A.Ş

Unknown

Comparison of Cefdinir and Cefdinir/Clavulanic Acid Combination in Adults

Acute Exacerbation of Chronic Bronchitis | Community-Acquired Pneumoniae

Turkey
University of Pittsburgh

Recruiting

Emphysema Research Registry and Biosample Repository

Chronic Obstructive Pulmonary Disease | Emphysema | Chronic Bronchitis

United States
CSA Medical, Inc.

Active, not recruiting

Metered Cryospray for the Treatment of Patients With Chronic Obstructive Pulmonary Disease With Chronic Bronchitis

COPD | Chronic Bronchitis

Netherlands, United Kingdom
Hospitales Universitarios Virgen del Rocío
Fondo de Investigacion Sanitaria

Unknown

Effects of Exercise Training on Systemic Inflammation an Muscle Repair According to the Obstructive Chronic Pulmonary Disease (COPD) Phenotype

Emphysema | Chronic Bronchitis | Obstructive Chronic Pulmonary Disease

Spain
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Sustained Effects of Hypertonic Saline on Mucociliary Clearance in Subjects With Chronic Bronchitis

Chronic Obstructive Pulmonary Disease | COPD | Chronic Bronchitis

United States
University of British Columbia
GlaxoSmithKline

Completed

Inhaled Steroid Reduces Systemic Inflammation in COPD

Chronic Obstructive Pulmonary Disease | Emphysema | Chronic Bronchitis

Canada
University of North Carolina, Chapel Hill

Withdrawn

Novel Therapies for Muco-Obstructive Lung Diseases: Testing the Transnasal Pulmonary Delivery Device in COPD/CB Subjects (tPAD)

COPD | Chronic Bronchitis

United States
Spyridon Fortis
American Thoracic Society

Recruiting

HHHFA in COPD Patients, With Chronic Bronchitis

Pulmonary Disease, Chronic Obstructive

United States
AstraZeneca

Completed

Epidemiology of Chronic Bronchitis in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease | Chronic Bronchitis
University of California, Los Angeles
Dey, L.P.

Withdrawn

Perforomist Versus Foradil Evaluated by Inspiratory Capacity and High Resolution Computed Tomography (HRCT)

Chronic Obstructive Pulmonary Disease | Emphysema | COPD | Chronic Bronchitis

United States
Isala

Completed

The Effect of Azithromycin in Patients With Chronic Obstructive Pulmonary Disease (COPD) and Chronic Productive Cough (CACTUS)

Chronic Obstructive Pulmonary Disease | Cough | Chronic Bronchitis

Netherlands
Yuhan Corporation

Completed

Safety/Tolerability and Efficacy of YHD001 in Patients With Acute and Chronic Bronchitis

Chronic Bronchitis | Acute Bronchitis

Korea, Republic of
University of Monastir

Completed

STI Combined to Valsalva Maneuver for the Diagnosis of Left Ventricular Dysfunction in COPD Exacerbations (STICOPD)

Obstructive Chronic Bronchitis With Acute Exacerbation

Tunisia
Ionis Pharmaceuticals, Inc.

Terminated

A Study to Assess the Safety, Tolerability, and Efficacy of ION-827359 in Participants With Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD) With Chronic Bronchitis (CB)

Chronic Obstructive Pulmonary Disease | Chronic Bronchitis

Germany, Czechia, Hungary, United Kingdom
Weill Medical College of Cornell University

Completed

The Natural History of Gene Expression in the Lung Cells of Non-Smokers, Smokers and Ex-Smokers in Health and Disease

Smoking | Smoking Cessation | Emphysema | Chronic Obstructive Pulmonary Disease (COPD) | Chronic Bronchitis

United States
National Jewish Health
GlaxoSmithKline

Terminated

Evaluating Genes in Sputum to Measure Drug Response in COPD

Emphysema | Chronic Obstructive Pulmonary Disease (COPD) | Chronic Bronchitis

United States
Jiangxi Qingfeng Pharmaceutical Co. Ltd.

Unknown

A Study of Andrographolide Sulfonate in Patients With Acute Exacerbation of Chronic Bronchitis

Acute Exacerbation of Chronic Bronchitis

China
PharmaKing

Completed

Comparative Evaluate the Efficacy to Acute and Chronic Bronchitis

Acute Exacerbation of Chronic Bronchitis

Korea, Republic of
Gala Therapeutics, Inc.

Active, not recruiting

Gala Early Feasibility Study of RheOx (Gala_EFS)

Chronic Bronchitis | Copd Bronchitis

United States

Clinical Trials on Obstructive Chronic Bronchitis

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CROs in Macedonia

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