Clinical Trials on Ocular Hypotension

Total 14524 results

Santen Inc.

Completed

A Phase IIb Safety and Efficacy Study of DE-126 Ophthalmic Solution in Primary Open-Angle Glaucoma or Ocular Hypertension- Angel Study

Open-angle Glaucoma, Ocular Hypertension

United States, Japan
Medical University of Vienna

Completed

An Open Study Comparing the Effects of Moxaverine on Ocular Blood Flow in Patients With Age- Related Macular Degeneration, Primary Open Angle Glaucoma and Healthy Control Subjects

Glaucoma | Macular Degeneration | Regional Blood Flow

Austria
Otsuka Beijing Research Institute

Recruiting

OPC-1085EL in the Treatment of Primary Open Angle Glaucoma or Ocular Hypertension in Chinese Subjects

Open Angle Glaucoma or Ocular Hypertension

China
Santen Inc.

Completed

Multi-center Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension

Open-angle Glaucoma or Ocular Hypertension

United States
Qlaris Bio, Inc.

Recruiting

Qlaris Study of QLS-111 in Combination With a PGA for OAG and/or OHT Patients

Glaucoma | Open-angle Glaucoma (OAG) | Ocular Hypertension (OHT)

United States
University of California, San Diego
Bausch & Lomb Incorporated

Completed

Study Comparing the Effects of Latanoprostene Bunod and Timolol on Retinal Blood Vessel Density and Visual Acuity

OAG - Open-Angle Glaucoma | OHT - Ocular Hypertension

United States
University of California, San Diego
Aerie Pharmaceuticals

Withdrawn

Effects of Netarsudil and Timolol on Retinal Blood Vessel Density and Visual Acuity

OAG - Open-Angle Glaucoma | OHT - Ocular Hypertension
Santen Pharmaceutical Co., Ltd.

Completed

A Phase III Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution Compared With Latanoprost Ophthalmic Solution in Subjects With OAG or OHT

Open Angle Glaucoma or Ocular Hypertension

Singapore
Santen Pharmaceutical Co., Ltd.

Completed

A Long-term Study of DE-117 Ophthalmic Solution Monotherapy and Concomitant Use of DE-117 Ophthalmic Solution With Timolol Ophthalmic Solution in Patients With OAG or OH: RENGE Study

Open Angle Glaucoma or Ocular Hypertension

Japan
Santen Pharmaceutical Co., Ltd.

Completed

DE-111 Ophthalmic Solution in Patients With Open Angle Glaucoma or Ocular Hypertension

Open Angle Glaucoma or Ocular Hypertension

Japan
Eye Therapies, LLC

Completed

Study Evaluating the Safety and Intraocular Pressure (IOP) Lowering Response of Brimonidine Tartrate Ophthalmic Solution in Subjects With Open Angle Glaucoma or Ocular Hypertension

Glaucoma and Ocular Hypertension

United States
University of Sao Paulo

Completed

Additive Intra-ocular Pressure Reduction Effect of Fixed Combination of Maleate Timolol 0.5%/Dorzolamide 2% on Monotherapy With Latanoprost in Patients With Elevated Intra-ocular Pressure

Glaucoma

Brazil
Ocular Therapeutix, Inc.

Completed

A Study to Evaluate the Long Term Safety of OTX-TP (Sustained Release Travoprost) Intracanalicular Insert

Open Angle Glaucoma and Ocular Hypertension

United States
Santen Pharmaceutical Co., Ltd.

Completed

A Comparative Confirmatory Study of STN1012600 in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension

Primary Open Angle Glaucoma, Ocular Hypertension

Japan
Aerie Pharmaceuticals

Completed

Study of Netarsudil Ophthalmic Solution in Japanese/Japanese-American Subjects With Open-angle Glaucoma or Ocular Hypertension

Primary Open Angle Glaucoma or Ocular Hypertension

United States
University Hospital, Toulouse

Unknown

Study of Changes in Retrofoveolar Choroidal Thickness During Aerobic Exercise (MOPAS)

Choroid Disease | Hypertension Ocular

France
Santen Inc.

Completed

DE-117 Spectrum 5 Study

Primary Open-angle Glaucoma and Ocular Hypertension

United States
Santen Pharmaceutical Co., Ltd.

Completed

A Study Assessing the Safety and Efficacy of DE-117 in Subjects With POAG or OH Who Are Non-/Low-responders to Latanoprost: FUJI Study

Primary Open Angle Glaucoma or Ocular Hypertension

Japan
Alcon Research

Completed

AL-54478 Proof of Concept Study

Open-angle Glaucoma (OAG) | Ocular Hypertension (OHT)
Daniel Moore
Pfizer

Terminated

Safety Study of Latanoprost Slow Release Insert (Latanoprost SR)

Primary Open Angle Glaucoma (POAG) | Ocular Hypertension (OHT)

United States
Julie Dawson

Completed

RCT to Investigate if Prostaglandin Analogue Drops Increase the Risk of Cystoid Macular Oedema After Cataract Surgery. (CMO)

Open Angle Glaucoma and Cataract

United Kingdom
Democritus University of Thrace

Completed

Ocular Surface Disease and IOP Monitoring With Travoprost Without Conservatives

Glaucoma | Ocular Surface Disease | Glaucoma; Drugs

Greece
Santen Inc.

Completed

Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution Once Daily and Twice Daily in Subjects With Primary Open-Angle Glaucoma SPECTRUM 6

Primary Open-angle Glaucoma and Ocular Hypertension

United States
Aerie Pharmaceuticals

Completed

Study of Netarsudil Ophthalmic Solution in Subjects With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)

Primary Open Angle Glaucoma or Ocular Hypertension

United States
Ono Pharma USA Inc

Completed

Single and Multiple Dose Escalation and Two-sequence Crossover Study of ONO-9054 in Patients With Ocular Hypertension or Mild Open-angle Glaucoma

Ocular Hypertension (OHT) | Mild Open Angle-glaucoma (OAG)

United States
Medical University of Vienna

Recruiting

Retinal Photoreceptor Outer Segment Length Before and After Light Stimulation - a Pilot Study

Primary Open-angle Glaucoma | Macular Degeneration, Dry

Austria
OcuTherix, Inc.

Terminated

Safety and Efficacy of Deep Wave Trabeculoplasty (DWT) in Primary Open Angle Glaucoma and Ocular Hypertension

Primary Open-angle Glaucoma (POAG) | Ocular Hypertension (OHT)

Philippines
Inotek Pharmaceuticals Corporation

Completed

Study of Trabodenoson in Adults With Ocular Hypertension or Primary Open-angle Glaucoma (MATrX-1)

Ocular Hypertension (OHT) | Primary Open-Angle Glaucoma (POAG)

United States
Prince of Songkla University

Completed

The Performances of Spectral Domain Optical Coherence Tomography (OCT) for Distinguishing Glaucomatous Eyes (cirrusOCT)

Normal Population | Glaucoma Patient | Glaucoma Suspect Patient | RNFL Thickness by Location | Macular Thickness by Location

Thailand
Inotek Pharmaceuticals Corporation

Completed

Study of Fixed-Dose Combinations of Trabodenoson and Latanoprost in Adults With OHT or POAG

Ocular Hypertension (OHT) | Primary Open-Angle Glaucoma (POAG)

United States
Inotek Pharmaceuticals Corporation

Completed

A Phase II Study to Evaluate the Additivity of Trabodenoson to Latanoprost in Adults With Ocular Hypertension or Primary Open-Angle Glaucoma

Ocular Hypertension (OHT) | Primary Open-Angle Glaucoma (POAG)

United States
Centre hospitalier de l'Université de Montréal...

Recruiting

Endoscopic Assisted Anterior Hyaloid Peeling in Boston Type 1 Keratoprosthesis (KPro-HP-Endo) (KPro-HP-Endo)

Postoperative Complications | Endoscopy | Vitrectomy | Corneal Transplantation | Glaucoma and Ocular Hypertension

Canada
Medical University of Vienna

Completed

Effect of Xalacom® (Latanoprost/Timolol) and Combigan® (Brimonidine/Timolol) Fixed Combination on Intraocular Pressure and Ocular Blood Flow in Patients With Primary Open Angle Glaucoma or Ocular Hypertension

Ocular Physiology | Retina

Austria
Assiut University

Unknown

Effect of Hyaluronidase on Intraocular Pressure

Intraocular Pressure Low
Allergan

Completed

Safety and Efficacy Study of Brimonidine/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertension

Ocular Hypertension

United States
Peking University First Hospital

Unknown

Efficacy Comparison of Xalatan and Azopt on POAG and OH

Ocular Hypertension
Santen Pharmaceutical (Taiwan) Co., LTD

Completed

Preservative-free Fixed-dose Combination of Tafluprost 0.0015% / Timolol 0.5% in Patients With Open-angle Glaucoma or Ocular Hypertension: Clinical Effectiveness, Tolerability and Safety in a Real World Setting

Primary Open Angle Glaucoma | Ocular Surface Disease

Taiwan
Allergan

Completed

A Retrospective Evaluation of the Intraocular Pressure Spikes With Loteprednol and Loteprednol/Tobramycin

Ocular Hypertension

United States
Bausch & Lomb Incorporated

Withdrawn

A Study to Evaluate the Effect of Latanoprostene Bunod Ophthalmic Solution 0.024% on Episcleral Venous Pressure and Outflow Facility in Participants With Ocular Hypertension

Ocular Hypertension

United States
Singapore Eye Research Institute

Completed

Safety and Efficacy of Liposomal Latanoprost in Ocular Hypertension

Ocular Hypertension
Allergan

Completed

Safety and Efficacy Study of Brimonidine/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertension

Ocular Hypertension

United States
Allergan

Completed

Safety and Efficacy Study of Bimatoprost in Patients With Glaucoma or Ocular Hypertension

Ocular Hypertension

United States
Allergan

Completed

Safety and Efficacy Study of Bimatoprost/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertension

Ocular Hypertension

United States, Canada
Allergan

Completed

Safety and Efficacy Study of Bimatoprost/Timolol Fixed Combination in Patients Wtih Glaucoma or Ocular Hypertension

Ocular Hypertension

United States
Allergan

Completed

Safety and Efficacy Study of Bimatoprost/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertension

Ocular Hypertension

Germany, Canada, United States, Austria
Allergan

Completed

Safety and Efficacy Study of Brimonidine/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertension

Ocular Hypertension

United States
Mayo Clinic

Terminated

Intraocular Pressure in Ocular Hypertensives With Scleral Lens Wear

Ocular Hypertension

United States
University of Houston

Completed

The Effect of a Scleral Lens on the Anterior Chamber Depth and Minimum Rim Width

Ocular Hypertension

United States
Sensimed AG
Yale University

Terminated

IOP Patterns in Ocular Hypertensive Patients Newly Converted to Glaucoma vs Stable Ocular Hypertensive Patients

Ocular Hypertension

United States
Intuor Technologies, Inc.

Completed

Clinical Evaluation of CATS Tonometer Prism

Ocular Hypertension

United States

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