Clinical Trials on Operative, Non Cardiac, Thoracic Disease in United Kingdom

Total 12454 results

Imperial College Healthcare NHS Trust

Recruiting

Delirium After Cardiac Surgery in Intensive Care Units (DaCsi-ICU)

Cardiac Surgery | Intensive Care Unit Delirium | Post Operative Delirium

United Kingdom
Edwards Lifesciences

Completed

Assisted Fluid Management IDE Study (AFM)

Abdominal Surgery | Pelvic Surgery | Non-Cardiac/ Non-Thoracic Surgery | Major Peripheral Vascular Surgery

United States
Medtronic - MITG

Completed

A Post-market Study of the Endo GIA™ Reinforced Reload With Tri-Staple™ Technology

Non-emergent, Abdominal or Thoracic Procedures

United Kingdom
Oxford University Hospitals NHS Trust

Completed

FLOTOR Pilot Study (FLOTOR)

Esophageal Cancer | Chylothorax | Thoracic Duct Intra-Operative Injury

United Kingdom
University College, London

Unknown

The Role of Alcohol Consumption in the Aetiology of Different Cardiovascular Disease Phenotypes: a CALIBER Study

Heart Failure | Mortality | Peripheral Arterial Disease | Cardiac Arrest | Ventricular Arrhythmias | Acute Myocardial Infarction | Unstable Angina | Sudden Cardiac Death | Abdominal Aortic Aneurysm | Chronic Stable Angina | Coronary Heart Disease (CHD) | Non-ST Elevation Myocardial Infarction (nSTEMI) | ST Elevation... and other conditions

United Kingdom
VA Office of Research and Development

Completed

Pilot Testing a Home-Based Rehabilitation Intervention Designed to Improve Outcomes of Frail Veterans Following Cardiothoracic Surgery

Frailty | Coronary Artery Bypass Graft | Non-cardiac Thoracic Surgery

United States
Renibus Therapeutics, Inc.

Recruiting

An Evaluation of Patient Reported Outcomes and Clinical Outcomes

Post-Operative Complications in Cardiac Surgery

United States, Canada
Renibus Therapeutics, Inc.

Recruiting

Effect of RBT-1 on Reducing the Risk of Post-Operative Complications in Subjects Undergoing Cardiac Surgery

Post-Operative Complications in Cardiac Surgery

United States, Canada
Boehringer Ingelheim

Completed

The Study Observes How Long Patients With Non-small Cell Lung Cancer (NSCLC) Benefit From Treatment With Epidermal Growth Factor Tyrosine Kinase Inhibitor (EGFR-TKI) When Given Either for Uncommon Mutations or for Common Mutations in the Sequence Afatinib Followed by Osimertinib (UpSwinG)

Non-squamous, Non-Small Cell Lung Cancer

United Kingdom
QIAGEN Gaithersburg, Inc
Amgen

Active, not recruiting

Testing of DNA Extracted From Tumor Tissue Biopsy Samples Using Therascreen KRAS RGQ PCR Kit

Non Small Cell Lung Cancer

United Kingdom
University Hospital Southampton NHS Foundation...
Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust

Unknown

Exercise Intervention During Chemotherapy in Advanced Lung Cancer Patients (EMBRACE)

Non Small Cell Lung Cancer | Non Small Cell Lung Cancer Stage IIIB | Non Small Cell Lung Cancer Metastatic

United Kingdom
Imperial College London

Completed

Non-invasive Mapping Using Ultra-high Frequency Electrocardiography

Left Bundle-Branch Block | Right Bundle-Branch Block | Non-Specific Intraventricular Conduction Defect

United Kingdom
Bayer
Janssen Research & Development, LLC

Completed

Study to Gather Information on the Kidney Function of Patients With Non-valvular Atrial Fibrillation (Irregularly Heart Beats Which is Not Caused by a Heart Valve Problem) Treated With Rivaroxaban or Vitamin K Antagonists (ANTENNA)

Non-Valvular Atrial Fibrillation

United Kingdom
European Organisation for Research and Treatment...

Active, not recruiting

Genetics of EGFR (Epidermal Growth Factor Receptor) Mutation Study (GEM)

EGFR Mutation Positive Non Small Cell Lung Cancer

United Kingdom
Agenus Inc.

Completed

Study of the Feasibility to Derive Vaccine From Tumor Tissue in Patients With Non-Small Cell Lung Cancer

Lung Cancer | Non-Small-Cell Lung Carcinoma | Pulmonary Cancer

United Kingdom
Royal Marsden NHS Foundation Trust
Bristol-Myers Squibb

Active, not recruiting

SBRT With Immunotherapy in Early Stage Non-small Cell Lung Cancer: Tolerability and Lung Effects (STILE)

Non-small Cell Lung Cancer Stage I | Non-small Cell Lung Cancer Stage II

United Kingdom
Achilles Therapeutics UK Limited

Terminated

Long-Term Follow-Up Study of Patients Receiving ATL001

Melanoma | Advanced Non Small Cell Lung Cancer

United Kingdom
QIAGEN Gaithersburg, Inc
Amgen

Active, not recruiting

Clinical Study Testing DNA Extracted From Tumour Tissue Biopsy Samples, Using the Therascreen® KRAS RGQ PCR Kit

Non-small Cell Lung Cancer

United Kingdom
Beth Israel Deaconess Medical Center

Completed

Efficacy of Transversus Abdominis Plane (TAP) Block Techniques: Surgeon vs Anesthesia - Ultrasound Guidance

Post Operative Analgesia | Non-inferiority Trial

United States
Institute of Cancer Research, United Kingdom
Merck Sharp & Dohme LLC; Merck Serono GmbH, Germany

Recruiting

POTENT - Tepotinib in Combination With Pembrolizumab in NSCLC (POTENT)

Non Small Cell Lung Cancer | Advanced Cancer

United Kingdom
AstraZeneca

Completed

A Phase I Study of ZD1839 and Palliative Thoracic Radiotherapy in Patients With Non-small-cell Lung Cancer

Non-small-cell Lung Cancer

United Kingdom
Cancer Research UK

Completed

AST-VAC2 Vaccine in Patients With Non-small Cell Lung Cancer

Advanced Non-small Cell Lung Cancer

United Kingdom
University of Hull
Hull University Teaching Hospitals NHS Trust

Withdrawn

Comprehensive Geriatric Assessment in Elderly Non-Small Cell Lung Cancer Patients

Lung Cancer | Non-small Cell Lung Cancer

United Kingdom
Oxford University Hospitals NHS Trust
National Institute for Health Research, United Kingdom

Completed

Hyperpolarized Xenon Gas MR Imaging in NSCLC Radiotherapy

Non-small Cell Lung Cancer

United Kingdom
Royal Marsden NHS Foundation Trust

Unknown

Evaluation of Stents to Open Restricted Airways in Patients With Centrally Placed Non-small Cell Lung Cancer (RESTORE-AIR)

Non-small Cell Lung Cancer

United Kingdom
University College, London
Hoffmann-La Roche

Active, not recruiting

Deciphering Antitumour Response and Resistance With INtratumour Heterogeneity (DARWINII)

Non-small Cell Lung Cancer

United Kingdom
Liverpool Heart and Chest Hospital NHS Foundation...

Withdrawn

The Effect Of Aspirin On Survival in Lung Cancer

Non Small Cell Lung Cancer | Aspirin | Survival

United Kingdom
The Christie NHS Foundation Trust
AstraZeneca; University of Manchester

Completed

MEK Inhibitor and Thoracic Radiotherapy Trial (MEKRT)

Non Small Cell Lung Cancer

United Kingdom
St. George's Hospital, London

Completed

Indexed Aortic Area in Bicuspid Aortic Valve Aortopathy

Thoracic Aortic Aneurysm | Bicuspid Cardiac Valve

United Kingdom
University Hospital Plymouth NHS Trust

Completed

Coronary Assessment for Mortality Prediction (CAMP)

Peri-operative Mortality | Coronary Artery Calcium

United Kingdom
The Cleveland Clinic

Completed

Evaluating Heat Transfer With the Esophageal Cooling Device

Non-cardiac Surgery

United States
Royal Marsden NHS Foundation Trust
Merck Sharp & Dohme LLC

Terminated

PembRolIzuMab and Stereotactic Body Radiotherapy In Metastatic Non-small-cell lunG Cancer Patients (PRIMING)

Metastatic Non-small-cell lunG Cancer

United Kingdom
NanoMab Technology (UK) Limited
King's College London; Guy's and St Thomas' NHS Foundation Trust

Recruiting

PD-L1 Expression in Lung Cancer (PELICAN)

Non-Small Cell Lung Cancer

United Kingdom
Bayer

Recruiting

A Study to Learn About How BAY2927088 Affects the Level of Dabigatran or Rosuvastatin in the Blood When These Drugs Are Taken Together in Healthy Participants

Healthy Volunteers | Advanced Non-small Cell Lung Cancer | EGFR Mutation | HER2 Mutation

United Kingdom
Imperial College London

Completed

Mechanisms and Innovations in Cardiac Resynchronisation Therapy (MIC)

Heart Failure | Left Bundle-Branch Block | Left Ventricular Systolic Dysfunction | Right Bundle-Branch Block | Non-Specific Intraventricular Conduction Defect

United Kingdom
European Organisation for Research and Treatment...

Unknown

Evaluation of FLT-PET and DWI-MRI in Patients With NSCLC Treated With a Platinum-based Doublet as Preoperative Chemo (EVIDENCE)

Non-small Cell Lung Carcinoma

Italy, United Kingdom
University College, London

Completed

Cisplatin, Vinorelbine, and Radiation Therapy in Treating Patients With Stage III Non-Small Cell Lung Cancer That Cannot Be Removed By Surgery (SOCCAR)

Lung Cancer

United Kingdom
The Christie NHS Foundation Trust

Unknown

Gemcitabine Plus Supportive Care in Treating Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Lung Cancer

United Kingdom
Hoffmann-La Roche

Completed

A Study of Avastin (Bevacizumab) in Combination With Thoracic Radiation and Chemotherapy in Patients With Advanced Non-Squamous Non-Small Cell Lung Cancer.

Non-Squamous Non-Small Cell Lung Cancer

Netherlands, United Kingdom
The Christie NHS Foundation Trust

Unknown

Paclitaxel and Carboplatin Chemotherapy Compared With Standard Chemotherapy in Treating Patients With Stage III or Stage IV Non-small Cell Lung Cancer That Cannot Be Removed During Surgery

Lung Cancer

United Kingdom
The Christie NHS Foundation Trust

Unknown

Hospitalization Rates of Patients With Non-Small Cell Lung Cancer Treated With Gemcitabine and Either Cisplatin or Carboplatin

Lung Cancer

United Kingdom
King's College Hospital NHS Trust

Completed

Laparoscopic Single Incision -Vs- Multiple Incision Gastric Band Surgery (SIMIS)

Surgery | Post-operative Pain | Post-operative Recovery

United Kingdom
National Cancer Institute (NCI)

Unknown

Standard Therapy Given With or Without Combination Chemotherapy in Treating Patients With Non-small Cell Lung Cancer

Lung Cancer

United Kingdom
University Hospital Birmingham

Unknown

Gemcitabine in Combination With Either Cisplatin or Carboplatin in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer

Lung Cancer

United Kingdom
GlaxoSmithKline

Not yet recruiting

Evaluation of Programmed Death Ligand 1 (PDL1) Response to Treatment in Patient-derived Organoids and Immune-marker Positron Emission Tomography (PET) Scanning in Non-small Cell Lung Cancer (NSCLC)

Lung Cancer, Non-Small Cell

United Kingdom
Lisette Nixon

Completed

ISoToxic Accelerated RadioTherapy in Locally Advanced Non-small Cell Lung Cancer: The Phase I/II I-START Trial (I-START)

Locally Advanced Non-small Cell Lung Cancer

United Kingdom
The Leeds Teaching Hospitals NHS Trust

Completed

A Study to Determine the Feasibility and Acceptability of Conducting a Phase III Randomised Controlled Trial Comparing Stereotactic Ablative Radiotherapy With Surgery in paTients With Peripheral Stage I nOn-small Cell Lung Cancer cOnsidered Higher Risk of Complications From Surgical Resection (SABRTOOTHv1)

Oncology

United Kingdom
King's College London
King's College Hospital NHS Trust; Guy's and St Thomas' NHS Foundation Trust; National Institute for Health Research, United Kingdom

Suspended

A Psychoeducational Intervention Supporting Patients With an Inherited Cardiac Condition (PISICC)

Cardiomyopathies | Inherited Cardiac Conduction Disorder

United Kingdom
The Christie NHS Foundation Trust
AstraZeneca

Completed

A Translational Study Investigating PD-L1 Expression After Radiotherapy for Non-small Cell Lung Cancer (PD-RAD)

Non-Small Cell Lung Cancer

United Kingdom
Medical Research Council
European Organisation for Research and Treatment of Cancer - EORTC

Completed

Surgery With or Without Preoperative Chemotherapy in Treating Patients With Resectable Non-small Cell Lung Cancer

Lung Cancer

United Kingdom

Clinical Trials on Operative, Non Cardiac, Thoracic Disease in United Kingdom

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