Clinical Trials on Opioid Dependence in Canada

Total 164 results

University of British Columbia

Completed

Associations Between Analgesia Nociception Index and Preoperative Anxiety (PANIC)

Anxiety | Cesarean Section | Opioid Consumption

Canada
Centre for Addiction and Mental Health
Canadian Institutes of Health Research (CIHR)

Completed

Fixed or Self-Titrated Dosages of Sativex on Cannabis Users

Cannabis Dependence

Canada
Ciusss de L'Est de l'Île de Montréal

Not yet recruiting

Impact of Administration of Esmolol on Nociception Level-guided Control of Nociception. (ESMONOL)

Anesthesia | Opioid Use, Unspecified | Nociceptive Pain

Canada
Sunnybrook Health Sciences Centre

Active, not recruiting

Opioid Requirements Post Discharge of Patients Having Total Knee Arthroplasty (TKA)

Pain | Rehabilitation | Opioid Use | Knee Arthropathy

Canada
Centre for Addiction and Mental Health

Completed

Smoking While on Transdermal Nicotine Replacement Therapy: Effects on Craving and Cessation

Nicotine Dependence

Canada
Centre for Addiction and Mental Health

Completed

Initial Screening of Gemfibrozil as a Novel Treatment for Tobacco Addiction

Nicotine Dependence

Canada
Centre for Addiction and Mental Health
Pfizer; Ontario Lung Association

Completed

The Effect of Varenicline on D2/D3 Receptor Binding in Smokers

Nicotine Dependence

Canada
Centre for Addiction and Mental Health
Ontario Lung Association

Terminated

Prazosin for Smoking Cessation

Nicotine Dependence

Canada
Centre for Addiction and Mental Health

Completed

Nicotine Metabolizers and [11C]-(+)-PHNO (MET)

Nicotine Dependence

Canada
Centre for Addiction and Mental Health
Nuraleve, Inc.

Withdrawn

Transcranial Direct Current Stimulation in a Smoking Cessation Trial (tDCS)

Nicotine Dependence

Canada
Centre for Addiction and Mental Health

Terminated

Efficacy and Neural Correlates of Personalized Treatment With Transdermal Nicotine Replacement (iT-NRT)

Tobacco Use Disorder | Nicotine Dependence

Canada
Centre for Addiction and Mental Health
Global Research Awards for Nicotine Dependence (GRAND)

Completed

The MATCH (Medication Aids for Tobacco Cessation and Health) Study (MATCH)

Tobacco Use Disorder | Nicotine Dependence

Canada
Centre for Addiction and Mental Health
Canadian Tobacco Control Research Initiative

Terminated

Baclofen for Smoking Cessation in a Non-Psychiatric Population (Baclofen)

Nicotine Dependence

Canada
Centre for Addiction and Mental Health
Canadian Tobacco Control Research Initiative

Terminated

Testing a Full Substitution Therapy Approach As Treatment of Tobacco Dependence

Nicotine Dependence

Canada
Centre for Addiction and Mental Health
The Royal Ottawa Mental Health Centre; North York General Hospital; Institute... and other collaborators

Completed

Appropriate Opioid Quantities for Acute Pain - Pharmacist Study

Acute Pain | Opioid Use

Canada
Centre for Addiction and Mental Health

Terminated

Pharmacotherapy for Alcohol Dependence in Convicted Drinking Drivers

Alcohol Dependence

Canada
Centre for Addiction and Mental Health
Health Canada

Completed

Pilot Study of Text Message Brief Interventions for Problem Drinkers

Alcohol Dependence

Canada
Centre hospitalier de l'Université de Montréal...
Maisonneuve-Rosemont Hospital

Active, not recruiting

Persistent Opioid Consumption After Major Abdominal Surgery and Its Determinants (POCAS)

Chronic Pain | Opioid Use | Major Abdominal Surgery

Canada
Centre for Addiction and Mental Health
Ottawa Heart Institute Research Corporation; Canadian Cancer Society (CCS)

Completed

Personalized Dosing of Nicotine Replacement (NRT to Effect)

Tobacco Use Disorder | Nicotine Dependence

Canada
Oregon Health and Science University
National Institute on Drug Abuse (NIDA)

Completed

Comparing Treatments for HIV-Infected Opioid and Alcohol Users in an Integrated Care Effectiveness Study (CHOICES)

Opioid Use Disorder | Alcohol Use Disorder

Canada, United States
Centre for Addiction and Mental Health
Health Canada

Completed

Helping Problem Drinkers on the Internet

Alcohol Dependence

Canada
McGill University Health Centre/Research Institute...

Completed

Intravenous Lidocaine for Laparoscopic Cholecystectomy

Postoperative Pain | Opioid Consumption

Canada
Ankara City Hospital Bilkent

Completed

Comparison of the Intraoperative and Postoperative Effects of Ultrasound-guided Erector Spina Plane Block and Posterior Quadratus Lumborum Block in Patients Undergoing Lumbar Stabilization Surgery

Quadratus Lumborum Block | Opioid Consumption | Postprocedural Analgesia | Erector Spina Plan Block

Turkey
McGill University Health Centre/Research Institute...

Recruiting

Eliminating Narcotic Prescriptions From Outpatient Minimally Invasive Gynecologic Surgery (eNARCOS)

Pain, Postoperative | Opioid Use

Canada
University of Alberta

Completed

Comparison of Short-term Sustained-release Opioid in Open Abdominal Urologic Surgeries

Pain, Acute | Opioid Use

Canada
Montreal Heart Institute

Unknown

The Prevalence of Chronic Pain and Continued Opioid Use After Cardiac Surgery (Doul-Card)

Chronic Pain | Cardiac Surgery | Opioid Use

Canada
McGill University Health Centre/Research Institute...

Terminated

TAP Block for Open Radical Prostatectomy.

Postoperative Pain | Opioid Consumption | Incidence of Nausea and Vomiting | Assessment of Recovery

Canada
Indivior Inc.

Recruiting

Evaluating the SUBLOCADE Treatment Exit Strategy

Opioid Use Disorder

United States, Canada
Ciusss de L'Est de l'Île de Montréal

Recruiting

Dexmedetomidine and Ketamine in VATS Surgery

Postoperative Pain | Opioid Use

Canada
University Health Network, Toronto

Recruiting

Improving Pain Disability With the Use of Oral Cannabinoids

Chronic Pain | Cannabis | Opioid Use

Canada
York University
University of Manitoba

Completed

Testing the Efficacy of an Online Treatment Program for Heavy Cannabis Use

Marijuana Use | Marijuana Dependence

Canada
Centre for Addiction and Mental Health

Completed

Electronic Cigarettes in Daily Dependent Smokers

Nicotine Dependence | Substance Withdrawal Syndrome

Canada
Centre for Addiction and Mental Health
Canadian Institutes of Health Research (CIHR); Canadian Tobacco Control Research...

Completed

Study of Varenicline (Champix) for Smoking Cessation/Reduction in Patients With Bipolar Disorder

Nicotine Dependence

Canada
IWK Health Centre

Completed

Trial of Pregabalin for Post-operative Pain in Women Undergoing Abdominal Hysterectomy

Postoperative Pain | Opioid Use

Canada
University of Saskatchewan

Terminated

Improving Labour Induction Analgesia: Epidural Fentanyl Bolus at Epidural Initiation for Induction of Labour

Labor Pain | Obstetric Pain | Induction of Labor Affected Fetus / Newborn | Epidural | Obstetric Anesthesia Problems | Opioid

Canada
Indivior Inc.

Active, not recruiting

Buprenorphine Extended-Release Subcutaneous Injection (RBP-6000) in High-risk Users

Moderate to Severe Opioid-use Disorder

United States, Canada
Columbia University
National Institute on Drug Abuse (NIDA); University of Miami; Weill Medical College... and other collaborators

Active, not recruiting

Integrated HIV Prevention and HCV Care for PWID (M2HepPrEP)

HIV Prevention | Opioid Use | HCV | Intravenous Drug Usage

Canada, United States
Centre hospitalier de l'Université de Montréal...

Recruiting

Joint Effort 2.0: a Mobile Application With University Students (JOINTEFFORT)

Cannabis | Cannabis Dependence | Cannabis Use | Cannabis Smoking | Cannabis Use, Unspecified

Canada
Unity Health Toronto

Recruiting

Superficial Parasternal Intercostal Plane Block in Cardiac Surgery Trial (EPOCH)

Chronic Pain | Anesthesia, Local | Opioid Use Disorder | Post-operative Pain | Post-cardiac Surgery | Post-operative Delirium

Canada
Stanford University
Mayo Clinic; University of British Columbia; Albert Einstein College of Medicine and other collaborators

Completed

Pain Control Following Sinus Surgery

Pain | Postoperative Pain | Sinusitis | Opioid Use | Opioid Abuse | Narcotic Use | Otolaryngologic Disease

United States, Canada
University of British Columbia
Provincial Health Services Authority

Withdrawn

Tobacco Retraining of Automatic Approach to Treat Individuals With Tobacco Dependence and Severe Concurrent Disorders.

Tobacco Retraining of Automatic Approach | Placebo Task

Canada
Health Sciences North Research Institute
Dedicated Anesthesia Research Enhancement Grant

Completed

How Does the Addition of Adductor Canal Block to Local Infiltration Affect Recovery in Patients Undergoing Total Knee Arthroplasty? A Feasibility Study. (TRUE KnORTH)

Knee Osteoarthritis | Opioid Use | Arthritis Knee | Knee Disease

Canada
Mount Sinai Hospital, Canada

Completed

A Comparison of Post-Operative Analgesia Requirements In Recreational Cannabis Users Versus Cannabis Naïve Inflammatory Bowel Disease Patients

Cannabis Use, Opioid Consumption

Canada
Salem Anaesthesia Pain Clinic

Recruiting

Ketamine Enhances Analgesia and Mood in Chronic Pain Patients

Mood Disorder; Opioid | Mood Insomnia

Canada
Centre hospitalier de l'Université de Montréal...

Completed

Cannabidiol and Cocaine Craving/Dependence (CBD)

Substance Use Disorder | Cocaine Dependence | Withdrawal From Addictive Substance; Detoxification

Canada
Centre for Addiction and Mental Health
Canadian Cancer Society (CCS)

Recruiting

Smoking Cessation and Menstrual Cycle Phase (MC-NRT)

Smoking Cessation | Tobacco Smoking | Substance Use Disorders | Nicotine Dependence | Nicotine Use Disorder

Canada
Centre for Addiction and Mental Health
Academic Health Science Centres

Completed

Feasibility Study of Oral Naloxone for Treatment of Methadone-induced Constipation

Constipation

Canada
Cannabis Research Associates

Unknown

Cannabis for Opioid Substitution Trial (COST)

Cannabis Use | Opioid Use | Pain Syndrome

Canada
St. Justine's Hospital

Completed

Dexmedetomine as Adjuvant for Spinal Anesthesia in Elective Cesarian Sections : a Pilot Study

Analgesia | Dexmedetomidine | Anesthesia, Spinal | Anesthesia, Obstetrical | Analgesics, Opioid | Analgesics, Non-Narcotic | Analgesia, Obstetrical

Canada
Ottawa Hospital Research Institute

Unknown

E-Cigarette Inner City RCT

Substance Use | Mental Illness | Tobacco Dependence | COPD Asthma

Canada

Clinical Trials on Opioid Dependence in Canada

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