Clinical Trials on Opioid Abuse

Total 3559 results

Member Companies of the Opioid PMR Consortium
HealthCore, Inc.

Completed

Study to Eval Relation Btw Doctor/Pharmacy Shopping & Outcomes of Misuse, Diversion, Abuse, Addiction by Med Rec Review

Opioid-Related Disorders | Drug Abuse | Opiate Addiction | Narcotic Abuse
Hospital for Special Surgery, New York

Completed

Opioid Education in Total Knee Arthroplasty

Arthropathy of Knee | Opioid Use | Opioid Abuse | Post Operative Pain | Opioid Misuse

United States
Shanna Babalonis, PhD
National Institute on Drug Abuse (NIDA)

Recruiting

Reinforcing Effects of Marijuana and Opioids

Marijuana Use | Opioid Use

United States
Member Companies of the Opioid PMR Consortium
World Health Information Science Consultants, LLC; IMS Health

Completed

Cross-Sectional Study to Define and Validate "Doctor/Pharmacy Shopping" as Outcomes Suggestive of Abuse and/or Addiction

Opioid-Related Disorders | Drug Abuse | Opiate Addiction | Narcotic Abuse
Shanna Babalonis, PhD
National Institute on Drug Abuse (NIDA)

Completed

Opioid and Cannabinoid Interactions

Opioid Use | Marijuana Usage

United States
Pain Therapeutics

Completed

Study to Evaluate the Subjective Effects of PTI-801 in Non-Physically Dependent Subjects With a History of Drug Abuse

Opioid-Related Disorders

United States
Western Michigan University
National Institute on Drug Abuse (NIDA); RTI International; DynamiCare Health...

Not yet recruiting

OUD Smartphone Services

Opioid-Related Disorders | Drug Abuse
University of California, Los Angeles

Completed

Postoperative Opt-In Narcotic Treatment Study (POINT)

Postoperative Pain | Analgesia | Opioid Use | Opioid Abuse | Narcotic Use | Endocrine Surgery

United States
Qure Healthcare, LLC
Ascend Learning

Completed

Assessing Opioid Care Practices Using CPV Patient Simulation Modules

Pain | Pain, Acute | Pain, Chronic | Opioid-use Disorder | Opioid Withdrawal | Pain, Neuropathic | Opioid Abuse and Addiction

United States
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Employment-based Reinforcement of Naltrexone Ingestion and Abstinence

Substance Abuse, Intravenous | Opioid-Related Disorders | Heroin Dependence | Cocaine-Related Disorders

United States
National Institute on Drug Abuse (NIDA)
Yale University

Completed

The Efficacy of Methadyl Acetate (LAAM) and Contingency Management Procedures for Treating Dual Opioid and Cocaine Abuse - 1

Substance-Related Disorders | Contingency Management | Heroin Dependence | Opioid Dependence | Behavior Therapy | Alcohol & Drug Use | Cocaine | LAAM

United States
The University of Texas Health Science Center,...
National Institute on Drug Abuse (NIDA)

Recruiting

Substance Abuse Pre-Treatment Screening Study

Alcohol Dependence | Substance Abuse | Cocaine Dependence | Opiate Dependence | Cocaine Abuse

United States
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

The Therapeutic Workplace Initiation Study

Substance Abuse, Intravenous | Opioid-Related Disorders | Heroin Dependence | Cocaine-Related Disorders

United States
National Institute on Drug Abuse (NIDA)

Completed

Medication Adherence Therapy for Opioid Abusing Pain Patients

Pain | Chronic Disease | Prescription Opioid Abuse

United States
Member Companies of the Opioid PMR Consortium

Terminated

Discontinuation vs Continuation of Long-term Opioid Therapy in Suboptimal and Optimal Responders With Chronic Pain

Opioid-Related Disorders | Drug Abuse | Opiate Addiction | Narcotic Abuse

United States
Hunter Holmes Mcguire Veteran Affairs Medical Center
VA Mental Illness Research, Education and Clinical Centers

Completed

Neurobehavioral Measurement of Substance Users in Outpatient Treatment Setting

Cannabis Dependence | Opioid-use Disorder | Cocaine Use Disorder | Cocaine Dependence | Opiate Dependence

United States
University of Houston
National Institute on Drug Abuse (NIDA)

Unknown

University of Houston Drug Abuse Research Development Program II (UHDARDP-II)

Heroin Dependence

United States
Analgesic Solutions

Unknown

Determining Genetic Biomarkers Predictive of the Development of Prescription Opioid Addiction

Usage of Prescription Opioids

United States
Columbia University

Terminated

A Multimodal Enhanced Recovery Program in Anorectal Surgery (ARSE)

Pain, Postoperative | Colorectal Disorders | Opioid Dependence | Patient Satisfaction | Opioid Use | Opioid Abuse | Anorectal Disorder

United States
NYU Langone Health
National Institutes of Health (NIH)

Recruiting

ED Observation for Opioid Use Disorder

Opiod Use Disorder

United States
Johns Hopkins University

Completed

Employment-based Reinforcement to Motivate Drug Abstinence in the Treatment of Drug Addiction. - 2

Behavior, Addictive | Heroin Dependence | Opioid Dependence | Cocaine Dependence | Cocaine Abuse

United States
University of Chicago
Agency for Healthcare Research and Quality (AHRQ); ACCESS Community Health...

Active, not recruiting

I-COPE Study: Opioid Use and Pain Management in Older Adults (I-COPE)

Chronic Pain | Opioid-use Disorder | Opioids

United States
Pfizer

Completed

A Clinical Study To Characterize The Pharmacokinetics And The Effects Of Food On Oxycodone In Healthy Volunteers

Chronic Pain | Analgesia | Acute Pain | Opioid-related Disorders | Narcotic Abuse

United States
University of New Mexico
National Institute on Drug Abuse (NIDA); Johns Hopkins University; Duke University and other collaborators

Recruiting

Pain and Opioids: Integrated Treatment In Veterans (POSITIVE)

Chronic Pain | Opioid-use Disorder | Opioids; Harmful Use

United States
Mount Sinai Hospital, Canada

Completed

A Comparison of Post-Operative Analgesia Requirements In Recreational Cannabis Users Versus Cannabis Naïve Inflammatory Bowel Disease Patients

Cannabis Use, Opioid Consumption

Canada
Indivior Inc.

Completed

Treatment of Opioid Dependent Patients With Suboxone: Acceptability & Safety Data From Real Life Scenario (Study P05603)

Opioid-Related Disorders | Drug Abuse | Opiate Dependence
Indivior Inc.

Completed

Acceptability and Safety of Switching From Subutex or Other Opioid Drug Dependence Therapy to Suboxone (NIS P05444)

Opioid-Related Disorders | Drug Abuse | Opiate Dependence

Austria
The University of Texas Health Science Center,...
National Institute on Drug Abuse (NIDA); University of Texas

Terminated

Pharmacotherapy Dosing Regimen in Cocaine and Opiate Dependent Individuals - 8

Opiate Dependence | Cocaine Abuse

United States
National Institute on Drug Abuse (NIDA)
Mclean Hospital

Completed

Treatment Efficacy for Drug Abuse and AIDS Prevention - 1

Heroin Dependence | Cocaine-Related Disorders

United States
Pfizer

Completed

Abuse Potential Assessment of Intranasally Administered EMBEDA Compared To Morphine Sulfate Controlled Release And Placebo

Chronic Pain | Analgesia | Opioid-related Disorders | Narcotic Abuse
London School of Hygiene and Tropical Medicine

Completed

Conflict Between Maternal Autonomy and Child Health in Substance-use

Substance-Related Disorders | Substance Abuse, Intravenous | Alcohol-Related Disorders | Pregnancy | Marijuana Abuse | Opioid-Related Disorders | Cocaine-Related Disorders | Neonatal Abstinence Syndrome | Amphetamine-Related Disorders | Inhalant Abuse | Pregnancy, High-Risk

United Kingdom
Yale University
National Institute on Drug Abuse (NIDA)

Completed

HIV Risk Reduction and Drug Abuse Treatment in Malaysia

Opiate Dependence

United States, Malaysia
Indivior Inc.

Completed

Preference for Subutex® (Buprenorphine) Versus Suboxone® (Buprenorphine/Naloxone) in Opioid Dependent Patients on Subutex® (Study P05094)(COMPLETED)

Drug Abuse | Opiate Dependence | Opiate-related Disorders
Cannabis Research Associates

Unknown

Cannabis for Opioid Substitution Trial (COST)

Cannabis Use | Opioid Use | Pain Syndrome

Canada
National Institute on Drug Abuse (NIDA)
Mclean Hospital

Completed

Treatment Efficacy for Drug Abuse and AIDS Prevention - 2

Heroin Dependence | Cocaine-Related Disorders

United States
T. John Winhusen, PhD
National Institute on Drug Abuse (NIDA); The Emmes Company, LLC

Recruiting

Medication Treatment for Opioid Use Disorder in Expectant Mothers: Infant Neurodevelopmental Outcomes Sub-study (MOMs-INO)

Pregnancy Related | Opioid-Related Disorders | Substance Abuse | Drug Abuse | Drug Addiction | Neonatal Abstinence Syndrome | Neonatal Opiate Withdrawal Syndrome | Drug Abuse in Pregnancy

United States
The Ottawa Hospital

Not yet recruiting

Standardization of Post-operative Opiate Prescriptions for Same-day Ankle and Wrist Fracture Surgeries

Surgery | Opioid Use | Post-operative Pain | Fracture, Ankle | Fracture Wrist | Prescription Opioid Abuse
Indivior Inc.

Completed

Observational Study of Misuse of High Dose Buprenorphine (Subutex® or Generic) in Opiate-Addicted Patients in France (Study P05186AM1)(COMPLETED) (OPUS R)

Naloxone | Drug Abuse | Opiate Dependence | Buprenorphine | Opiate-related Disorders
Vanderbilt University Medical Center
National Institute on Drug Abuse (NIDA)

Recruiting

Low-dose Buccal Buprenorphine: Relative Abuse Potential and Analgesia

Pain | Analgesia | Abuse Opioids

United States
Stanford University
Mayo Clinic; University of British Columbia; Albert Einstein College of Medicine and other collaborators

Completed

Pain Control Following Sinus Surgery

Pain | Postoperative Pain | Sinusitis | Opioid Use | Opioid Abuse | Narcotic Use | Otolaryngologic Disease

United States, Canada
Massachusetts General Hospital
Cambridge Health Alliance; MaineHealth

Recruiting

Evaluation of Medical Cannabis and Prescription Opioid Taper Support for Reduction of Pain and Opioid Dose in Patients With Chronic Non-Cancer Pain

Pain | Marijuana Use | Opioid Use

United States
Boston Medical Center

Completed

RESPECT-PLUS: Services for Infants With Prenatal Opiate Exposure (RESPECT-Plus)

Child Abuse | Child Development | Opioid Use Disorder | Neonatal Abstinence Syndrome | Child Neglect

United States
Member Companies of the Opioid PMR Consortium
Kaiser Permanente; Kaiser Permanente Washington

Active, not recruiting

A Prospective Investigation of the Risks of Opioid Misuse, Abuse, and Addiction Among Patients Treated With Opioids for the Treatment of Chronic Pain

Opioid-Related Disorders | Drug Abuse | Opiate Addiction | Narcotic Abuse

United States
University of Pittsburgh

Terminated

Opioid Induced Loss of Local Anesthetic Potency in Patients Undergoing Total Knee Arthroplasty

Opioid Tolerance, Opioid Naive, Opioid Exposure

United States
Universidade Federal de Alfenas

Terminated

Oral Pregabalin as Preemptive Analgesia in Abdominal Hysterectomy

Pain, Postoperative | Analgesia | Opioid Abuse | Gabapentin Adverse Reaction

Brazil
Vireo Health

Completed

Do Discounted Vouchers for Medical Cannabis Reduce Opioid Use in Adults With Pain (ReLeaf-V)

Chronic Pain | Opioid Use | Marijuana

United States
University of Manitoba

Completed

Evaluation of a Patient-Centred, Multidisciplinary Opioid Tapering Program for Individuals With Chronic Non-Cancer Pain on Long Term Opioid Therapy

Opioid Use | Pain, Chronic | Hyperalgesia | Opioids; Harmful Use

Canada
Yale University
National Institute on Drug Abuse (NIDA)

Withdrawn

HIV Risk Reduction and Drug Abuse Treatment in Iran

HIV Infections | Opiate Dependence

United States, Iran, Islamic Republic of
Albert Einstein College of Medicine
Laura and John Arnold Foundation; Vireo Health

Completed

Does Medical Cannabis Reduce Opioid Use in Adults With Pain (ReLeaf-E)

Chronic Pain | Opioid Use | Marijuana

United States
Rutgers University

Terminated

Use Surveillance Technology to Reduce Elder Abuse Recidivism (MC)

Aging | Elder Abuse | Self Neglect | Domestic Abuse

United States

Clinical Trials on Opioid Abuse

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CROs in Japan

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