Clinical Trials on Optic Pathway Glioma

Total 3455 results

Gustave Roussy, Cancer Campus, Grand Paris

Unknown

High Risk Primitive Neuroectodermal (PNET) Brain Tumors in Childhood

Neuroectodermal Tumors, Primitive | Medulloblastoma | Brain Tumors

France
Florida International University
Nicklaus Children's Hospital f/k/a Miami Children's Hospital

Completed

Ex Vivo Drug Sensitivity Testing and Mutation Profiling

Recurrent Childhood Ependymoma | Recurrent Childhood Acute Lymphoblastic Leukemia | Recurrent Childhood Acute Myeloid Leukemia | Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Recurrent Childhood Rhabdomyosarcoma | Recurrent Childhood Soft Tissue Sarcoma | Recurrent Childhood Large... and other conditions

United States
European Organisation for Research and Treatment...

Recruiting

Observational Study for Assessing Treatment and Outcome of Patients With Primary Brain Tumours Using cIMPACT-NOW and 2021 WHO Classification

Glioma | Ependymoma | Hemangiopericytoma | Diffuse Midline Glioma, H3 K27M-Mutant | Germ Cell Tumor | Embryonal Tumor | Hemangioblastoma | Glioneuronal Tumor | Choroid Plexus Tumor | Pineal Tumors | Tumor of the Sellar Region | Pineal Tumor | Melanocytic Tumor of CNS

Spain
Mayo Clinic
National Cancer Institute (NCI)

Completed

Wild-Type Reovirus in Combination With Sargramostim in Treating Younger Patients With High-Grade Relapsed or Refractory Brain Tumors

Glioma | Recurrent Childhood Medulloblastoma | Childhood Atypical Teratoid/Rhabdoid Tumor | Diffuse Intrinsic Pontine Glioma | Refractory Brain Neoplasm | Recurrent Childhood Anaplastic Oligodendroglioma | Recurrent Childhood Glioblastoma | Recurrent Primitive Neuroectodermal Tumor | Childhood Astrocytoma and other conditions

United States
Ruhr University of Bochum

Completed

Incisional Negative Pressure Wound Therapy for Resection of Soft Tissue Tumors

Soft Tissue Sarcoma | Tumor | Lipoma

Germany
University of Maryland, Baltimore
Keep Punching Foundation

Recruiting

LITT Followed by Hypofractionated RT for Recurrent Gliomas (GCCC 19140)

Glioma | Neoplasms | Glioblastoma | Brain Tumor

United States
M.D. Anderson Cancer Center

Completed

Glioblastoma Multiforme (GBM) Proton vs. Intensity Modulated Radiotherapy (IMRT)

Brain Cancer

United States
Canadian Cancer Trials Group
European Organisation for Research and Treatment of Cancer - EORTC; Trans Tasman...

Completed

Radiation Therapy With or Without Temozolomide in Treating Older Patients With Newly Diagnosed Glioblastoma Multiforme

Brain and Central Nervous System Tumors

Canada, Germany, Japan, Netherlands
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

High-Dose Methotrexate and Leucovorin in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
Wake Forest University Health Sciences
Emory University

Completed

A Trial of Poly-ICLC in the Management of Recurrent Pediatric Low Grade Gliomas (Poly-ICLC)

Brain Tumors

United States
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Completed

Everolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme (RTOG 0913)

Brain and Central Nervous System Tumors

United States, Israel, Canada
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Radiation Therapy Followed by Carmustine in Treating Patients Who Have Supratentorial Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States, Canada
Jonsson Comprehensive Cancer Center
Millennium Pharmaceuticals, Inc.

Completed

Bortezomib, Temozolomide, and Regional Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma

Brain and Central Nervous System Tumors

United States
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology; European Organisation for Research...

Completed

Radiation Therapy (RT) and Temozolomide (TMZ) in Treating Patients With Newly Diagnosed Glioblastoma or Gliosarcoma

Brain and Central Nervous System Tumors

Canada, United States
Abramson Cancer Center of the University of Pennsylvania
National Cancer Institute (NCI)

Terminated

Nelfinavir Mesylate, Radiation Therapy, and Temozolomide in Treating Patients With Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
Case Comprehensive Cancer Center
University of Cincinnati; OhioHealth Research Institute

Completed

Feasibility Trial of the Modified Atkins Diet and Bevacizumab for Recurrent Glioblastoma

Glioblastoma | Brain Tumor

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Terminated

Biological Therapy and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme (Poly-ICLC)

Brain and Central Nervous System Tumors

United States
European Organisation for Research and Treatment...
Pfizer

Completed

Radiation Therapy and Temsirolimus or Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

Brain and Central Nervous System Tumors

United Kingdom, Switzerland, Belgium, Italy, Germany, France, Netherlands, Spain
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Terminated

Temozolomide During and After Radiation Therapy in Treating Patients Who Have Undergone Previous Surgery and Placement of Gliadel Wafers for Newly Diagnosed Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
Radiation Therapy Oncology Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group; NCIC Clinical... and other collaborators

Completed

Radiation Therapy With or Without Chemotherapy in Treating Patients With Anaplastic Oligodendroglioma

Brain and Central Nervous System Tumors

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
Cancer Research UK
Immatics Biotechnologies GmbH

Completed

Vaccine Therapy, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United Kingdom
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Radiation Therapy, Temozolomide, and Irinotecan in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Terminated

Administration of CMV-Specific Cytotoxic T Cells in Patients With Glioblastoma Multiforme (COGLI)

Brain Cancer | Glioblastoma Multiforme | GBM

United States
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Radiation Therapy Plus Chemotherapy in Treating Patients With Supratentorial Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States, Canada
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Followed by Second-Look Surgery and Radiation Therapy in Treating Children With Nonmetastatic Medulloblastoma or Primitive Neuroectodermal Tumor

Untreated Childhood Medulloblastoma | Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor

United States
European Organisation for Research and Treatment...
NCIC Clinical Trials Group

Completed

Radiation Therapy With or Without Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Brain and Central Nervous System Tumors

Canada
Pfizer

Completed

Prinomastat Plus Temozolomide Following Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Completed

Penicillamine, Low Copper Diet, and Radiation Therapy in Treating Patients With Glioblastoma

Brain and Central Nervous System Tumors

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Completed

Gossypol (AT-101) and Temozolomide With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Stereotactic Radiosurgery and Radiation Therapy in Treating Patients With Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
Centre Leon Berard

Completed

Standard Radiation Therapy, Higher-Dose Radiation Therapy, or Chemotherapy in Treating Older Patients With Glioblastoma Multiforme

Brain and Central Nervous System Tumors

France
National Cancer Institute (NCI)

Completed

Surgery Followed by Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Motexafin Gadolinium Plus Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
National Cancer Institute (NCI)

Completed

Motexafin Gadolinium in Treating Patients With Glioblastoma Multiforme Who Are Undergoing Radiation Therapy to the Brain

Brain and Central Nervous System Tumors

United States
Ivy Brain Tumor Center
GlaxoSmithKline

Recruiting

A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma

Glioblastoma | Brain Tumor | GBM | Brain Neoplasms, Adult, Malignant

United States
Theodore S. Johnson
Augusta University

Recruiting

Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer

Glioblastoma | Ependymoma | Medulloblastoma | Primary Brain Tumor

United States
Zhejiang Cancer Hospital

Recruiting

Anlotinib to Malignant Brainstem Glioma

Glioma | Malignant Brain Stem Tumor

China
Guido A. Davidzon, MD, SM

Completed

[18F]DASA-23 and PET Scan in Evaluating Pyruvate Kinase M2 Expression in Patients With Intracranial Tumors or Recurrent Glioblastoma and Healthy Volunteers

Glioblastoma | Healthy Subject | Intracranial Neoplasm

United States
Kintara Therapeutics, Inc.

Active, not recruiting

Study of VAL-083 in Patients With MGMT Unmethylated, Bevacizumab-naive Glioblastoma in the Adjuvant or Recurrent Setting

Glioma | Glioblastoma | Brain Cancer | Glioblastoma Multiforme | GBM

United States
DelMar Pharmaceuticals, Inc.

Terminated

VAL-083 Phase 3 Study in Temozolomide-Avastin (Bevacizumab) Recurrent GBM (STAR-3)

Glioma | Glioblastoma | Brain Cancer | Glioblastoma Multiforme | GBM

United States
NCIC Clinical Trials Group

Completed

Temozolomide + Everolimus in Newly Diagnosed, Recurrent, or Progressive Malignant Glioblastoma Multiforme

Brain and Central Nervous System Tumors

Canada
Emory University
CURE Childhood Cancer, Inc.; Peach Bowl LegACy Fund

Completed

WP1066 in Children With Refractory and Progressive or Recurrent Malignant Brain Tumors

Brain Tumor | Medulloblastoma | Brain Metastases

United States
Wake Forest University Health Sciences
NovoCure Ltd.

Terminated

A Phase II Study of Optune (NovoTTF) in Combination With Bevacizumab (BEV) and Temozolomide (TMZ) in Patients With Newly Diagnosed Unresectable Glioblastoma (GBM)

Cancer of Brain and Nervous System

United States
Northwest Biotherapeutics

Active, not recruiting

Study of a Drug [DCVax®-L] to Treat Newly Diagnosed GBM Brain Cancer (GBM)

Glioma | Glioblastoma | Brain Cancer | Brain Tumor | Glioblastoma Multiforme | GBM | Grade IV Astrocytoma

United States, Germany, Canada, United Kingdom
Universitätsklinikum Hamburg-Eppendorf
Deutsche Kinderkrebsstiftung

Active, not recruiting

International Society of Paediatric Oncology (SIOP) PNET 5 Medulloblastoma

Brain Tumors

Germany, Denmark, United Kingdom, Belgium, Poland, Ireland, Austria, Italy, Czechia, France, Netherlands, Norway, Portugal, Spain, Sweden, Switzerland
NCIC Clinical Trials Group

Completed

Topotecan in Treating Patients With Recurrent Brain Tumors

Brain and Central Nervous System Tumors

Canada
University of Wisconsin, Madison

Completed

PET/CT Evaluation of Primary and Metastatic Brain Tumors With a Novel Radioiodinated Phospholipid Ether Analogue I-NM404

Glioblastoma Multiforme | Brain Metastases

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI); Jazz Pharmaceuticals

Completed

Mibefradil Dihydrochloride and Temozolomide in Treating Patients With Recurrent Glioma

Brain and Central Nervous System Tumors

United States
Santiago R. Leal-Noval
Instituto de Salud Carlos III

Unknown

Hemostasis Alterations in Neurosurgical Patients (ABCD)

Glioma | Surgery | Coagulopathy | Acquired Platelet Function Disorder | Thromboelastometry

Spain

Clinical Trials on Optic Pathway Glioma

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