Clinical Trials on Oral Cavity and Lip Precancerous Condition in Canada

Total 385 results

National Cancer Institute (NCI)

Terminated

Cisplatin With or Without WEE1 Inhibitor MK-1775 in Treating Patients With Recurrent or Metastatic Head and Neck Cancer

Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Recurrent Lip and Oral Cavity Squamous Cell Carcinoma | Recurrent Laryngeal Verrucous Carcinoma | Recurrent Metastatic Squamous Cell Carcinoma in... and other conditions

Canada
NRG Oncology
National Cancer Institute (NCI)

Recruiting

Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer

Oral Cavity Squamous Cell Carcinoma | Stage I Lip and Oral Cavity Cancer AJCC v8 | Stage II Lip and Oral Cavity Cancer AJCC v8 | Buccal Mucosa Squamous Cell Carcinoma | Floor of Mouth Squamous Cell Carcinoma | Gingival Squamous Cell Carcinoma | Hard Palate Squamous Cell Carcinoma | Lip Squamous Cell... and other conditions

United States, Canada
National Cancer Institute (NCI)

Active, not recruiting

Metformin Hydrochloride in Preventing Oral Cancer in Patients With an Oral Premalignant Lesion

Hyperplasia | Oral Cavity Carcinoma | Oral Leukoplakia | Erythroplakia

United States, Canada
University Health Network, Toronto

Completed

A Comparative Study of Ultrasound Versus CT Measurement of Tongue and Oral Cavity Size

Ultrasound Airway Imaging in Determining the Oral Cavity and Tongue Size

Canada
National Cancer Institute (NCI)

Recruiting

Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer

Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Lip and Oral Cavity Cancer AJCC v8 | Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Stage IVA Lip and Oral... and other conditions

United States, Canada
University of British Columbia

Recruiting

Mandibular Reconstruction Preplanning (ViPMR) (ViPMR)

Oral Cancer | Oral Cavity Cancer

Canada
University of British Columbia

Recruiting

Radial Forearm Donor Site Closure

Oral Cancer | Oral Cavity Cancer | Donor Site Complication

Canada
National Cancer Institute (NCI)
NRG Oncology; Canadian Cancer Trials Group

Active, not recruiting

Radiation Therapy With Durvalumab or Cetuximab in Treating Patients With Locoregionally Advanced Head and Neck Cancer Who Cannot Take Cisplatin

Head and Neck Squamous Cell Carcinoma | Oropharyngeal Squamous Cell Carcinoma | Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Lip and Oral Cavity Cancer AJCC v8 | Stage... and other conditions

United States, Canada
University of Calgary

Completed

Does the Harmonic Scalpel Reduce Blood Loss and OR Time in Major Head and Neck Cancer Surgery Undergoing Major Surgery for Oral Cavity Squamous Cell Carcinoma? (HS2)

Oral Cavity Squamous Cell Carcinoma, Treated With Surgery

Canada
University Health Network, Toronto
Pfizer

Completed

Study to Assess Biomarkers in Patients With Resectable Oral Cavity Cancer Randomized to Receive Preoperative Treatment

Oral Cavity Cancer

Canada
University Health Network, Toronto
AstraZeneca; Mirati Therapeutics Inc.

Withdrawn

Pre-operative Mocetinostat (MGCD0103) and Durvalumab (MEDI4736) (PRIMED) for Squamous Cell Carcinoma of the Oral Cavity (PRIMED-001)

Squamous Cell Carcinoma, Head And Neck | Squamous Cell Carcinoma Mouth | Resectable Squamous Cell Carcinoma of Oral Cavity

Canada
University Health Network, Toronto
Mirati Therapeutics Inc.

Completed

Sitravatinib (MGCD516) and Nivolumab in Oral Cavity Cancer Window Opportunity Study (SNOW)

Squamous Cell Carcinoma of the Oral Cavity | Squamous Cell Carcinoma, Head And Neck | Squamous Cell Carcinoma Mouth

Canada
British Columbia Cancer Agency
University of British Columbia; BC Cancer Foundation

Unknown

Innovative Approach to Triage Oral Precancer (iTOP)

Oral Cancer | Oral Premalignant Lesion

Canada
National Cancer Institute (NCI)

Completed

Vorinostat in Treating Patients With Locally Advanced, Recurrent, or Metastatic Adenoid Cystic Carcinoma

Recurrent Salivary Gland Carcinoma | Stage IVA Major Salivary Gland Cancer AJCC v7 | Stage IVB Major Salivary Gland Cancer AJCC v7 | Stage IVC Major Salivary Gland Cancer AJCC v7 | Tongue Carcinoma | Salivary Gland Adenoid Cystic Carcinoma | Recurrent Oral Cavity Adenoid Cystic Carcinoma | Stage... and other conditions

United States, Canada
National Cancer Institute (NCI)

Completed

SB-715992 in Treating Patients With Recurrent or Metastatic Head and Neck Cancer

Recurrent Metastatic Squamous Neck Cancer With Occult Primary | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous Cell Carcinoma... and other conditions

Canada
National Cancer Institute (NCI)

Terminated

Capecitabine and Vorinostat in Treating Patients With Recurrent and/or Metastatic Head and Neck Cancer

Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oral Cavity Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Stage IVA Oral Cavity Squamous Cell Carcinoma | Stage IVA Laryngeal Squamous Cell Carcinoma | Stage... and other conditions

Canada, United States
National Cancer Institute (NCI)

Active, not recruiting

Onalespib in Treating Patients With Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck Receiving Radiation Therapy and Cisplatin

Stage IVA Hypopharyngeal Squamous Cell Carcinoma AJCC v7 | Stage IVA Laryngeal Squamous Cell Carcinoma AJCC v7 | Stage IVA Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7 | Stage IVA Oropharyngeal Squamous Cell Carcinoma AJCC v7 | Stage IVB Hypopharyngeal Squamous Cell Carcinoma AJCC v7 | Stage IVB Laryngeal Squamous Cell Carcinoma AJCC... and other conditions

United States, Canada
University of British Columbia
British Columbia Cancer Agency; Terry Fox Research Institute

Unknown

Efficacy of Optically-guided Surgery in the Management of Early-staged Oral Cancer - COOLS TRIAL

Oral Cancer | High-grade Precancer

Canada
University of Arizona
National Cancer Institute (NCI)

Recruiting

Metformin for the Prevention of Oral Cancer in Patients With Oral Leukoplakia or Erythroplakia

Oral Leukoplakia | Erythroplakia

United States, Canada
University Health Network, Toronto

Completed

Biofeedback Rehabilitation to Improve Speaking and Eating in Public (Biofeedback)

Oral Cavity Squamous Cell Carcinoma

Canada
National Cancer Institute (NCI)

Terminated

Pioglitazone for Oral Premalignant Lesions

Oral Leukoplakia

United States, Italy, Canada
Brooklyn ImmunoTherapeutics, LLC

Completed

IRX-2 Regimen in Patients With Newly Diagnosed Stage II, III, or IVA Squamous Cell Carcinoma of the Oral Cavity (INSPIRE)

Squamous Cell Carcinoma of the Oral Cavity

United States, Brazil, United Kingdom, Canada
Lawson Health Research Institute

Recruiting

Preservation of Swallowing in Respected Oral Cavity Squamous Cell Carcinoma: Examining Radiation Volume Effects (PRESERVE): A Randomized Trial

Head and Neck Cancer

Canada, United States, Ireland, United Kingdom
National Cancer Institute (NCI)

Completed

Sunitinib Malate in Treating Patients With Recurrent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer

Stage IV Ovarian Epithelial Cancer | Recurrent Ovarian Epithelial Cancer | Recurrent Primary Peritoneal Cavity Cancer | Stage IV Primary Peritoneal Cavity Cancer | Recurrent Fallopian Tube Cancer | Stage IIIA Fallopian Tube Cancer | Stage IIIB Fallopian Tube Cancer | Stage IIIC Fallopian Tube Cancer and other conditions

Canada
Sunnybrook Health Sciences Centre
Celgene; Sunnybrook Research Institute

Withdrawn

Apremilast - Oral Lichen Planus Trial (APOLP)

Oral Lichen Planus

Canada
University of Calgary
Terry Fox Research Institute

Completed

Fluorescent Visualization in Early Oral Cancer

Oral Squamous Cell Carcinoma or Severe Dysplasia

Canada
National Cancer Institute (NCI)
NRG Oncology

Recruiting

Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

Stage IV Hypopharyngeal Squamous Cell Carcinoma AJCC v7 | Stage IV Laryngeal Squamous Cell Carcinoma AJCC v7 | Stage IV Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7 | Stage IV Oropharyngeal Squamous Cell Carcinoma AJCC v7 | Oropharyngeal p16INK4a-Negative Squamous Cell Carcinoma | Stage... and other conditions

United States, Canada, China
CEL-SCI Corporation
Teva Branded Pharmaceutical Products R&D, Inc.; Orient Europharma Co., Ltd.

Completed

Efficacy and Safety Study of Leukocyte Interleukin,Injection (LI) to Treat Cancer of the Oral Cavity (IT-MATTERS)

Squamous Cell Carcinoma of the Oral Cavity | Squamous Cell Carcinoma of the Soft Palate

Spain, Taiwan, United States, United Kingdom, Romania, India, Croatia, Belarus, Hungary, Bosnia and Herzegovina, Russian Federation, Austria, Canada, France, Israel, Italy, Malaysia, Poland, Serbia, Sri Lanka, Thailand, Turkey, Ukraine
Proteocyte Diagnostics Inc.

Recruiting

Early Prediction of Oral Cancer by S100A7 Immunohistochemistry Signature-based Assessment

Oral Neoplasm

Canada
British Columbia Cancer Agency
National Cancer Institute (NCI)

Completed

Inositol in Preventing Lung Cancer in Patients With Bronchial Epithelial Dysplasia Who Are Current or Former Smokers

Lung Cancer | Precancerous Condition

Canada
NCIC Clinical Trials Group

Terminated

Pilocarpine in Treating Patients With Dry Mouth Caused by Opioids

Quality of Life | Oral Complications

Canada
British Columbia Cancer Agency
National Cancer Institute (NCI); University of Cincinnati

Terminated

Green Tea Extract in Treating Current or Former Smokers With Bronchial Dysplasia

Tobacco Use Disorder | Lung Cancer | Precancerous Condition

Canada
Ottawa Hospital Research Institute

Recruiting

Photobiomodulation for the Prevention of Radiation Induced Oral Mucositis

Head and Neck Cancer | Radiation Dermatitis | Mucositis Oral

Canada
Université de Sherbrooke

Unknown

Effect of Nasal Continuous Positive Airway Pressure (CPAP) on Oral Feeding in Human Neonates

Oral Feeding in Human Neonates During Nasal CPAP

Canada
British Columbia Cancer Agency
AstraZeneca

Completed

Studying Genes in Blood and Lung Fluid Samples From Patients With Chronic Obstructive Pulmonary Disease With or Without a Previous Diagnosis of Lung Cancer or With Asthma Treated With Budesonide and Formoterol

Lung Cancer | Precancerous Condition

Canada
University of British Columbia

Recruiting

Global Hip Dysplasia Registry (GHDR)

Hip Dislocation, Congenital | Congenital Hip Dysplasia | Congenital Dysplasia of the Hip | Congenital Hip Dislocation | Hip Dysplasia, Congenital, Nonsyndromic | Congenital Hip Displacement | Dislocation Of Hip, Congenital | Dislocation, Congenital Hip | Displacement, Congenital Hip | Dysplasia, Congenital... and other conditions

Canada
Nova Scotia Health Authority

Recruiting

Trichloroacetic Acid as a Topical Treatment for Actinic Cheilitis

Actinic Cheilitis

Canada
University of British Columbia

Enrolling by invitation

Caregivers' eCourse for Recovery After Hip Fracture

Hip Fractures | Family

Canada
McGill University Health Centre/Research Institute...
Canadian Institutes of Health Research (CIHR); Greybox Solutions Inc.

Completed

HIP Mobile: A Community-based Monitoring, Rehabilitation and Learning e-System for Patients Following a Fracture

Hip Fractures

Canada
University of Alberta

Terminated

Pre-op Femoral Nerve Block for Hip Fracture

Hip Fractures

Canada
Rudy Reindl
Orthopaedic Trauma Association

Completed

Randomized Comparison of 2 Fixation Techniques for Unstable Intertrochanteric Hip Fractures (EMvsIM)

Hip Fractures

Canada
British Columbia Cancer Agency
National Cancer Institute (NCI)

Terminated

Pilot Study In Vivo Confocal Microscopy Probe for Cervical Precancer (Confocal)

Cervical Cancer | Precancerous Condition

Canada
Corin

Completed

Clinical and Radiographic Outcomes of the Corin Tri-Fit Total Hip Replacement

Avascular Necrosis | Congenital Hip Dysplasia | Osteoarthritis of Hip

Canada
Dr. Mohammad Auais, PhD

Completed

The Stronger at Home Study

Hip Fractures

Canada
Innovaderm Research Inc.
Galderma Canada

Completed

Short Incubation Methylaminolevulinate Photodynamic Therapy Without Occlusion

Actinic Keratosis

Canada
University Health Network, Toronto

Completed

Sentinel Lymph Node Mapping of Oral Cancer Using Near-Infrared Fluorescence Imaging (SLN Mapping)

Head and Neck Neoplasms

Canada
University of British Columbia

Not yet recruiting

Developmental Dysplasia of the Hip: Observation vs. Bracing

Hip Dysplasia | Developmental Dysplasia of the Hip | Hip Dysplasia, Congenital | Hip Dysplasia, Developmental

Canada
University of Calgary
Canadian Institutes of Health Research (CIHR)

Not yet recruiting

HIP Fracture Oral thromboPROphylaxis (Hip PRO Pilot) (HIP PRO Pilot)

Hip Fractures

Canada
Lawson Health Research Institute

Completed

Ultrasound Assessment of Heart and Lungs for Hip Fracture Procedure

Hip Fractures

Canada
Population Health Research Institute

Completed

Hip Fracture Impact on Vascular Events In Noncardiac Surgery patIents: a cOhort evaluatioN (Hip VISION): Pilot Study

Hip Fractures

Canada

Clinical Trials on Oral Cavity and Lip Precancerous Condition in Canada

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