Clinical Trials on Oral Cavity Leukoplakia

Total 2178 results

National Cancer Institute (NCI)

Completed

Bowman-Birk Inhibitor Concentrate in Preventing Cancer in Patients With Oral Leukoplakia

Lip and Oral Cavity Cancer | Oropharyngeal Cancer | Tongue Cancer | Oral Leukoplakia

United States
University of Zagreb

Completed

Comparison Between Two Different High Power Ablative Lasers in the Treatment of Oral Leukoplakia

Leukoplakic Lesions
National Cancer Institute (NCI)

Active, not recruiting

Metformin Hydrochloride in Preventing Oral Cancer in Patients With an Oral Premalignant Lesion

Hyperplasia | Oral Cavity Carcinoma | Oral Leukoplakia | Erythroplakia

United States, Canada
Thomas Jefferson University
National Cancer Institute (NCI)

Terminated

Metformin for the Prevention of Oral Cancer in Patients With Oral Premalignant Lesions

Oral Cavity Carcinoma | Leukoplakia | Erythroplakia | Proliferative Verrucous Leukoplakia

United States
Jonsson Comprehensive Cancer Center
Merck Sharp & Dohme LLC

Recruiting

Pembrolizumab in Treating Participants With Leukoplakia

Leukoplakia | Erythroleukoplakia | Verrucous Oral Leukoplakia

United States
Institut Pasteur

Completed

Infectious Aetiology of Potentially Malignant Disorders and Squamous Cell Carcinomas of the Oral Cavity (INECOC)

Squamous Cell Carcinoma of the Oral Cavity | Leukoplakia Oral

France
University of Erlangen-Nürnberg Medical School

Recruiting

Prediction of Malignant Transformation of Oral Leukoplakia Using a MAGE-A-based Immunoscore (PREDICT-OLP)

Oral Leukoplakia | Oral Lichen Planus | Oral Leukoplakia of Tongue | Oral Leukoplakia of Gingiva

Germany
King Khalid University

Not yet recruiting

Analyzing Handprint Patterns to Predict Oral Cancer Risks: A Comparative Study (QQA-FPD-PMML)

Oral Leukoplakia
University of Minnesota

Not yet recruiting

Pioglitazone-Metformin Combination Treatment for High Risk Oral Preneoplasia

Oral Leukoplakia

United States
University of California, San Francisco

Withdrawn

Intralesional 5-fluorouracil Injection for the Treatment of Oral Leukoplakia (OL_5FU)

Oral Leukoplakia

United States
National Taiwan University Hospital

Completed

Photodynamic Therapy for Oral Leukoplakia and Erythroleukoplakia

Oral Leukoplakia

Taiwan
National Taiwan University Hospital
National Health Research Institutes, Taiwan

Unknown

Least Invasive Nonlinear Light Microscopy

Oral Cancer | Oral Leukoplakia

Taiwan
Cairo University

Completed

Diagnostic Accuracy of Salivary DNA Integrity Index in Oral Malignant and Premalignant Lesions

Oral Cancer | Oral Leukoplakia | Oral Lichen Planus

Egypt
University of Arizona
National Cancer Institute (NCI)

Recruiting

Metformin for the Prevention of Oral Cancer in Patients With Oral Leukoplakia or Erythroplakia

Oral Leukoplakia | Erythroplakia

United States, Canada
National Cancer Institute (NCI)

Terminated

Photodynamic Therapy Using Aminolevulinic Acid in Treating Patients With Oral Leukoplakia

Oral Leukoplakia

United States
National Cancer Institute (NCI)

Completed

Rosiglitazone Maleate in Treating Patients With Oral Leukoplakia

Oral Leukoplakia

United States
University of Medicine and Dentistry of New Jersey

Terminated

A Phase II Trial to Assess the Effects of Green Tea in Oral Leukoplakia

Oral Leukoplakia

United States
National Cancer Institute (NCI)

Terminated

Pioglitazone for Oral Premalignant Lesions

Oral Leukoplakia

United States, Italy, Canada
All India Institute of Medical Sciences, New Delhi

Completed

Candida Associated Cytokines in Oral Leukoplakia

Oral Leukoplakia

India
The University of Hong Kong

Not yet recruiting

Oral Cancer Screening and Education in Hong Kong

Oral Cancer | Oral Leukoplakia | Erosive Lichen Planus | Oral Submucous Fibrosis | Proliferative Verrucous Leukoplakia | Oral Erythroplakia
Cairo University

Unknown

Diagnostic Accuracy of Salivary Gamma-synuclein in Oral Malignant and Premalignant Lesions

Oral Cancer | Oral Leukoplakia | Oral Lichen Planus | Premalignant Lesion
Postgraduate Institute of Dental Sciences Rohtak

Unknown

Evaluation of Effect of Topical Melatonin in Treatment of Oral Leukoplakia

Oral Leukoplakia

India
National Cancer Institute (NCI)

Completed

Pioglitazone Hydrochloride in Preventing Head and Neck Cancer in Patients With Oral Leukoplakia

Head and Neck Cancer | Oral Leukoplakia

United States
University College, London
University College London Hospitals

Completed

Oral Epithelial Dysplasia Informational Needs Questionnaire (ODIN-Q)

Quality of Life | Precancerous Conditions | Patient Engagement | Patient Participation | Oral Disease | Patient Satisfaction | Health Behavior | Precancerous Lesions | Oral Leukoplakia | Dental Diseases | Oral Lichen Planus | Dysplasia | Patient Preference | Information Seeking Behavior | Oral Epithelial Dysplasia | Oral... and other conditions

United Kingdom
Federico II University

Recruiting

Identification of Oral Lesions Through an Autofluorescence System

Keratosis | Oral Disease | Oral Cancer | Oral Leukoplakia | Oral Lichen Planus | Secondary Prevention | Autofluorescence

Italy
National Institute of Dental and Craniofacial Research...
National Cancer Institute (NCI)

Active, not recruiting

Biomarkers for Oral Cancer

Mouth Neoplasms | Oral Leukoplakia | Lichen Planus

United States
Fox Chase Cancer Center
National Cancer Institute (NCI)

Completed

Celecoxib in Preventing Head and Neck Cancer in Patients With Oral Leukoplakia

Head and Neck Cancer | Precancerous Condition

United States
Dalarna County Council, Sweden

Terminated

Intra and Extra Oral Inspection of Oral Mucosa

Oral Leukoplakia | Oral Lichen Planus | Erythroplakia

Sweden
The Oxford Dental College, Hospital and Research...

Completed

Comparison or Rose Bengal and Toluidine Blue Staining for Lesion Detection Efficacy

Oral Leukoplakia | Oral Lichen Planus | Premalignant Lesion
Beni-Suef University

Completed

Malondialdehyde and Nitrous Oxide as Salivary Biomarkers for Different Oral Lesions

Oral Cancer | Leukoplakia | Oral Lichen Planus | Oral Keratoses

Egypt
University Hospital, Basel, Switzerland

Recruiting

Reinnervated PAP Flap for Oral Cavity and Oropharyngeal Defect Reconstruction

Oral Cavity Defect | Oropharynx Defect

Switzerland
Institute of Head and Neck Studies and Education...

Completed

Aspirin Mouthwash in Treating Patients With Oral Leukoplakia

Precancerous Condition

United Kingdom
University of Palermo

Recruiting

SYsteMatical Trained learnIng aLgorithms for Oral carcInogenesiS Interpretation by Optical Coherence Tomography (SYMILIS OCT)

Oral Disease | Oral Cancer | Actinic Keratoses | Oral Leukoplakia | Oral Squamous Cell Carcinoma | Oral Lichen Planus | Graft-versus-host-disease | Proliferative Verrucous Leukoplakia | Actinic Cheilitis | Oral Potentially Malignant Disorder | Oral Erythroplakia | Oral Lichenoid Lesion

Italy
University of Washington
Blaze Bioscience Inc.

Recruiting

A Fluorescent Tumor Marking Agent, Tozuleristide, for Imaging Oral Cavity Squamous Cell Cancer and High-Grade Oral Cavity Dysplasia During Surgery

Stage III Lip and Oral Cavity Cancer AJCC v8 | Oral Cavity Squamous Cell Carcinoma | Stage I Lip and Oral Cavity Cancer AJCC v8 | Stage II Lip and Oral Cavity Cancer AJCC v8 | Stage IVA Lip and Oral Cavity Cancer AJCC v8

United States
Dana-Farber Cancer Institute
Bristol-Myers Squibb

Active, not recruiting

Safety and Efficacy of Nivolumab in Treating Oral Proliferative Verrucous Leukoplakia

Leukoplakia, Oral

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Widefield Fluorescence and Reflectance Imaging Systems and Oral Tissue Samples in Monitoring Participants at Risk for Developing Oral Cancer

Tobacco Use Disorder | Fanconi Anemia | Lichen Planus | Oral Neoplasm | Erythroplakia | Premalignant Lesion | Oral Cavity and Lip Precancerous Condition | Oral Cavity Leukoplakia

United States
Centre Hospitalier Universitaire Dijon

Completed

Spectrometry of Cancerous Lesions of the Oral Cavity (SpectrORL1)

Cancerous Lesions of the Oral Cavity

France
Ohio State University Comprehensive Cancer Center

Completed

Direct Visual Fluorescence in Finding Oral Cancer in High-Risk Patients and Patients Undergoing Routine Dental Care

Tongue Cancer | Lip and Oral Cavity Squamous Cell Carcinoma | Oral Cavity Verrucous Carcinoma | Stage 0 Lip and Oral Cavity Cancer

United States
Dow University of Health Sciences

Completed

Behavior Changing Intervention for Smokeless Tobacco and Betel Quid Use in Adolescents

Oral Cavity Carcinoma

Pakistan
Ohio State University Comprehensive Cancer Center

Recruiting

Transoral Robotic Surgery in Treating Patients With Benign or Malignant Tumors of the Head and Neck

Tongue Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Verrucous Carcinoma of the Larynx | Recurrent Verrucous Carcinoma of the Oral Cavity | Recurrent Adenoid... and other conditions

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Withdrawn

Photodynamic Therapy With HPPH in Treating Patients With Squamous Cell Carcinoma of the Oral Cavity

Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous Cell Carcinoma of the Oropharynx | Recurrent Verrucous Carcinoma of the Oral Cavity | Stage I Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage I Squamous Cell Carcinoma of the Oropharynx | Stage I Verrucous... and other conditions

United States
Fayoum University

Completed

Diagnostic Accuracy of lncRNA DQ786243 and miRNA146a in Saliva of Oral Potentially Malignant Lesions

Leukoplakia, Oral | Oral Lichen Planus | Potentially Malignant Lesions

Egypt
Medical University of South Carolina
Bristol-Myers Squibb

Completed

Trial of Nivolumab as a Novel Neoadjuvant Pre-Surgical Therapy for Locally Advanced Oral Cavity Cancer

Oral Cavity SCC

United States
Rutgers, The State University of New Jersey
National Cancer Institute (NCI); Rutgers Cancer Institute of New Jersey

Withdrawn

Hypofractionated Radiation Therapy Followed by Surgery in Treating Patients With Advanced Squamous Cell Carcinoma of the Oral Cavity

Tongue Cancer | Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage III Verrucous Carcinoma of the Oral Cavity | Stage IVA Verrucous Carcinoma of the Oral Cavity | Stage IVB Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage IVB Verrucous Carcinoma of the Oral Cavity | Stage IVA Squamous Cell Carcinoma of the Lip and Oral Cavity

United States
Memorial Sloan Kettering Cancer Center
Weill Medical College of Cornell University; Amrita Institute of Sciences,... and other collaborators

Completed

A Randomized Study of Sulindac in Oral Premalignant Lesions

Leukoplakia, Oral | Benign Neoplasms

United States, India
Ohio State University Comprehensive Cancer Center

Completed

Freeze-Dried Black Raspberries in Preventing Oral Cancer Recurrence in High At-Risk Appalachian Patients Oral Cancer Survivors

Tongue Cancer | Stage I Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage I Squamous Cell Carcinoma of the Oropharynx | Stage I Verrucous Carcinoma of the Oral Cavity | Stage II Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage II Squamous Cell Carcinoma of the Oropharynx | Stage... and other conditions

United States
Wake Forest University Health Sciences

Terminated

Esophagoscopy in Evaluating Treatment in Patients With Stage I-IV Head and Neck Cancer Who Are Undergoing Radiation Therapy and/or Chemotherapy

Stage I Adenoid Cystic Carcinoma of the Oral Cavity | Stage I Mucoepidermoid Carcinoma of the Oral Cavity | Stage I Squamous Cell Carcinoma of the Hypopharynx | Stage I Squamous Cell Carcinoma of the Larynx | Stage I Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage I Verrucous Carcinoma... and other conditions

United States
University Health Network, Toronto

Completed

A Comparative Study of Ultrasound Versus CT Measurement of Tongue and Oral Cavity Size

Ultrasound Airway Imaging in Determining the Oral Cavity and Tongue Size

Canada
National Cancer Institute (NCI)

Completed

Gene Therapy in Preventing Cancer in Patients With Premalignant Carcinoma of the Oral Cavity or Pharynx

Lip and Oral Cavity Cancer | Oropharyngeal Cancer | Tongue Cancer | Stage 0 Lip and Oral Cavity Cancer | Stage 0 Oropharyngeal Cancer

United States
University of Milan

Recruiting

Oral Potentially Malignant Disorders: Comparison Between Surgical Treatment and Wait and See Approach

Leukoplakia, Oral

Italy

Clinical Trials on Oral Cavity Leukoplakia

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Drug Interventions

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CROs in Congo, DR of

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