Clinical Trials on Organic Cation Transporter 1

Total 749 results

McMaster Children's Hospital

Unknown

Use of Sodium Bicarbonate in Patients Treated With Topiramate

Epilepsy | Metabolic Acidosis | Tubular Acidosis; Renal

Canada
Assistance Publique - Hôpitaux de Paris

Completed

Monocentric STUDY, Randomised Double Blinded (Healthy Subjects, or Transversal (Patients With Gitelman Syndrome) (DEPROGE)

Gitelman Syndrome | Potassium Depletion

France
Assistance Publique - Hôpitaux de Paris

Terminated

Dose-Dependent Effect of Thiazide in Dent's Disease Hypercalciuria (DESY)

Nephrolithiasis | Dent's Disease

France
University of Ljubljana
University Medical Centre Ljubljana

Completed

Periodontal Status and Pregnancy or Delivery Complications in Type 1 Diabetes Mellitus Pregnant Women

Diabetes Mellitus, Type 1 | Periodontitis | Periodontal Diseases | Pregnancy Complications | Delivery Complication | Pregnancy in Diabetic
Mayo Clinic

Recruiting

Prospective Research Rare Kidney Stones (ProRKS) (ProRKS)

Cystinuria | Hyperoxaluria | Dent Disease | Lowe Syndrome | Adenine Phosphoribosyltransferase Deficiency

United States, Canada, Iceland, Israel
University of Nebraska
Gilead Sciences

Completed

Bictegravir/Emtricitabine/Tenofovir Alafenamide (B/F/TAF) in HIV-1 Infected Patients With Active Illicit Substance usE (BASE)

HIV-1-infection

United States
Yuzuncu Yıl University

Completed

Cord Blood Nesfatin-1 and Irisin in the Intrauterine Growth Restricted Fetuses

Nesfatin-1 | Irisin | Intrauterine Growth Restriction

Turkey
Hospital Universitário Professor Edgard Santos

Unknown

A Randomized, Placebo-Controlled Study to Assess the Efficacy of Propantheline for the Treatment of Overactive Bladder

Overactive Bladder Associated With HTLV-1

Brazil
Imperial College London
Imperial College Healthcare NHS Trust

Recruiting

Psychological Impact of Pregnancy of Unknown Location (SOUL)

Anxiety | Ectopic Pregnancy | Pregnancy of Unknown Location

United Kingdom
Chelsea and Westminster NHS Foundation Trust

Completed

The Effect of Dolutegravir on Whole-body Insulin Sensitivity, Lipid and Endocrine Profile in Healthy Volunteers (DTG Clamp)

HIV-1-infection on Healthy Volunteers

United Kingdom
Universitair Ziekenhuis Brussel
KU Leuven

Unknown

Sulfamethoxazole for the Treatment of Primary PREPL Deficiency (SPPD)

Hypotonia Cystinuria Syndrome | Isolated PREPL Deficiency
National Taipei University of Nursing and Health...
Cardinal Tien Hospital

Completed

Effectiveness of Implementation of a Patient-centered Self-management Program in Patients With Hypertensive Nephropathy

Mental Health Wellness 1 | Self-management | Hypertensive Nephropathy | Self-efficacy

Taiwan
University of Padova

Unknown

Terlipressin Given As I.V. Boluses Versus Terlipressin Given As Continuous Intravenous Infusion In Patients With Cirrhosis And Type 1 Hepatorenal Syndrome

Cirrhosis | Type 1 Hepatorenal Syndrome

Italy
University of Utah

Recruiting

National Institute of Diabetes and Digestive Kidney Diseases* Share Plus: Continuous Glucose Monitoring With Data Sharing in Older Adults With Type 1 Diabetes* and Their Care Partners to Improve Time in Range and Reduce Diabetes Distress. (NIDDK T1D)

Diabetes Mellitus, Type 1

United States
University of California, San Diego
National Institute on Drug Abuse (NIDA)

Recruiting

Cannabis Use, Cognition, and the Endocannabinoid System in HIV

HIV-1-infection

United States
Imperial College London
Imperial College Healthcare NHS Trust

Recruiting

Assessment of Biomarkers in Pregnancy on Unknown Location and Ectopic Pregnancy (ABPEP)

Ectopic Pregnancy | Early Pregnancy | Early Pregnancy Loss | Pregnancy of Unknown Location

United Kingdom
Lei Li

Unknown

Functional Training for the Prevention of Deep Venous Thrombosis

Deep Venous Thrombosis | Gynecologic Neoplasm | Ankle Motion | Abdominal Breathing

China
Eloxx Pharmaceuticals, Inc.

Terminated

A Phase 2 Study of ELX-02 in Patients With Nephropathic Cystinosis

Genetic Disease | Cystinosis | Nonsense Mutation

Canada
Soroka University Medical Center
Ben-Gurion University of the Negev

Unknown

Parathyroid Hormone (PTH) Homeostasis in Bartter Syndrome

Hypocalcemia | Hypercalcemia

Israel
Indiana University

Completed

Effect of Dietary Protein Source on Phosphaturia, PTH and FGF23 in Patients With CKD 3 and 4

Chronic Kidney Disease

United States
University of Colorado, Denver
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Pathogenesis of Kidney Disease in Type 1 Diabetes: a Modern Kidney Biopsy Cohort (The PANDA Study) (PANDA)

Diabetes Complications | Type 1 Diabetes | Diabetic Kidney Disease | Diabetic Nephropathies | Autoimmune Diabetes

United States
MacroGenics
National Institute of Allergy and Infectious Diseases (NIAID); National Institutes... and other collaborators

Active, not recruiting

A Study of MGD020 Alone or Combined With MGD014 in Persons With HIV-1 on Antiretroviral Therapy

Human Immunodeficiency Virus I Infection | Immunodeficiency Virus Type 1, Human | Human Immunodeficiency Virus Type 1

United States
Cairo University

Recruiting

Penile Implant Intraoperative Measurements Planning Chart (PIIMP)

Erectile Dysfunction | Erectile Dysfunction Following Radical Prostatectomy | Erectile Dysfunction Following Simple Prostatectomy | Erectile Dysfunction With Diabetes Mellitus | Erectile Dysfunction Due to Arterial Disease | Erectile Dysfunction Due to Injury | Erectile Dysfunction Due to Neuropathy and other conditions

Egypt
University of Colorado, Denver
Icahn School of Medicine at Mount Sinai; Ohio State University; Joslin Diabetes...

Recruiting

PRenatal and Obstetric Maternal Exposures and ISlet Autoantibodies in Early Life (PROMISE)

Type 1 Diabetes | Pregnancy in Diabetic

United States
University of Pittsburgh
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Poor Sleep and Inflammation in HIV-Infected Adults (SASH)

Inflammation | Sleep Deprivation | HIV-1-infection

United States
Novo Nordisk A/S

Completed

An International Non-interventional Cohort Study to Evaluate the Safety of Treatment With Insulin Detemir in Pregnant Women With Diabetes Mellitus. Diabetes Pregnancy Registry

Diabetes Mellitus, Type 2 | Diabetes Mellitus | Diabetes Mellitus, Type 1

Israel, United Kingdom, France, Netherlands, Spain, Finland, Malaysia, Norway, Italy, Germany, Poland, Romania, Portugal, Ireland, Croatia, Greece
Nantes University Hospital

Unknown

Pancreas Allotransplantation for Diabetic Nephropathy and Mild Chronic REnal fAilure Stage Study (PANCREAS)

Type 1 Diabetes

United States, Italy, Brazil, Czech Republic, France
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth With Type 1 Diabetes (MANATEE-T1D)

Cardiovascular Diseases | Type 1 Diabetes | Diabetic Kidney Disease | Endothelial Dysfunction | Insulin Sensitivity

United States
Steno Diabetes Center Copenhagen
DSM Nutritional Products, Inc.

Completed

Effects of Probiotics and Fibers on Albuminuria in Persons With Type 1 Diabetes (ProFOS)

Type 1 Diabetes | Diabetic Kidney Disease | Albuminuria | Nephropathy

Denmark
Chiesi SA/NV

Enrolling by invitation

Observational Study to Assess the Quality of Life in Nephropathic Cystinosis Patients (PROREAL)

Nephropathic Cystinosis

Belgium
Tehran University of Medical Sciences

Unknown

Acetazolamide (AZ) for Management of Alkalosis in Bartter Syndrome (AZ)

Bartter Syndrome

Iran, Islamic Republic of
Assiut University

Not yet recruiting

Maternal alpha1 Antitrypsin as a Marker of Intrauterine Growth Restriction in Pre-eclamptic Women

Pre-Eclampsia | Intrauterine Growth Restriction | alpha1 Anti-trypsin
Yale University

Terminated

Aspirin to Prevent Preeclampsia in Women With Elevated Blood Pressure and Stage 1 Hypertension (ASPPIRE)

Pre-Eclampsia | Elevated Blood Pressure | Stage 1 Hypertension

United States
Lei Li

Completed

Immunotherapy for Recurrent Cervical Cancer Refractory to Platinum-based Chemotherapy

Chemotherapy | Recurrent Cervical Carcinoma | Immunotherapy | Anti-PD-1 Antibody | Persistent Advanced Cervical Carcinoma

China
McMaster University
CIHR Canadian HIV Trials Network

Completed

Estrogen, Probiotics and Vaginal Health to Prevent HIV Infection in ACB Women

HIV-1-infection | Bacterial Vaginoses

Canada
Taixing People's Hospital

Unknown

Effect of Vitamin D Supplement on Osteoprotegin Expression and Disease Progression in Patients With Chronic Kidney Disease Stage 1 and 2

Chronic Kidney Disease Stage 2 | Chronic Kidney Disease Stage 1

China
University Hospital Inselspital, Berne

Completed

Influence of Polymorphisms in the ATP6V1 Gene of the V-ATPase on the Development of Incomplete Distal Renal Tubular Acidosis

Nephrolithiasis | Acidosis, Renal Tubular | Vacuolar Proton-Translocating ATPases

Switzerland
National Taiwan University Hospital

Completed

Application of Wearable Devices to Build a Self-Management Model in Chronic Kidney Disease Patients

Chronic Kidney Disease stage4 | Chronic Kidney Disease stage3 | Chronic Kidney Disease Stage 2 | Chronic Kidney Disease Stage 1

Taiwan
Novo Nordisk A/S

Completed

A Study to Evaluate DCR-PHXC in Children and Adults With Primary Hyperoxaluria Type 1 and Primary Hyperoxaluria Type 2 (PHYOX2)

Kidney Diseases | Urologic Diseases | Genetic Disease | Primary Hyperoxaluria Type 1 (PH1) | Primary Hyperoxaluria Type 2 (PH2)

Poland, United States, United Kingdom, New Zealand, Australia, Canada, France, Germany, Israel, Italy, Japan, Lebanon, Netherlands, Romania, Spain
University of Colorado, Denver
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaborators

Active, not recruiting

MEtabolic and Renal Effects of AutoMAted Insulin Delivery Systems in Youth With Type 1 Diabetes Mellitus (MERMAID-T1D)

Diabetes Mellitus, Type 1 | Diabetic Kidney Disease | Diabetic Nephropathies | Diabetes Mellitus Complication | Metabolic Disease | Type1 Diabetes Mellitus | Autoimmune Diabetes | Juvenile Diabetes

United States
University of Virginia
DexCom, Inc.; Tandem Diabetes Care, Inc.

Withdrawn

Use of Closed Loop Insulin Delivery for Glucose Control in Patients With Insulin Dependent Diabetes Mellitus After Kidney Transplantation

Type 1 Diabetes | End Stage Renal Disease (ESRD) | Insulin-requiring Type 2 Diabetes Mellitus
Sun Yat-sen University

Not yet recruiting

Efficacy and Toxicity of Paclitaxel, Cisplatin Combined With Sindilimab in NACT for Locally Advanced Cervical Cancer

Cervical Cancer | Chemotherapy Effect | Neoadjuvant Therapy | Programmed Cell Death 1 Receptor / Antagonists & Inhibitors
Minia University Hospital

Completed

Use of Recombinant Factor VII as a Prophylactic Therapy for Adolescent Females With Heavy Menstrual Bleeding

Assessing the Bleeding Profile and the Quality of Life of the Enrolled Patients Before and 1 Year After Drug Intervention

Egypt
University of North Carolina, Chapel Hill
National Institute on Drug Abuse (NIDA); National Institute of Mental Health...

Completed

Treatment De-Intensification and Residual HIV-1 in Youth

HIV Infections | HIV-1

United States, Puerto Rico
Novo Nordisk A/S

Completed

Comparison of NovoFine® Needles (4 mm vs. 6 mm)

Diabetes Mellitus, Type 2 | Diabetes | Diabetes Mellitus, Type 1 | Delivery Systems

Denmark
Tibotec Pharmaceuticals, Ireland

Completed

A Phase 2 Study to Evaluate Pharmacokinetics, Safety and Efficacy of TMC114/Ritonavir (Rtv) in Human Immunodeficiency Virus (HIV)-1 Infected Children and Adolescents

HIV Infections | HIV-1

United States, France, Spain, Canada, South Africa, Argentina, Brazil, Romania
InLight Solutions

Unknown

Comparison of Noninvasive Blood Glucose Concentrations Relative to Finger Capillary Blood Glucose References

Type 1 Diabetes | Type 2 Diabetes | Gestational Diabetes

United States
Ruth M. Rothstein CORE Center
Virco

Unknown

A Comparison of Virco®TYPE HIV-1 Testing Versus Expert Interpretation of Genotypic Results for Control of HIV-1 Replication

HIV Infections | HIV-1

United States
Masonic Cancer Center, University of Minnesota

Withdrawn

Ph1 Study of FT538 Alone and With Vorinostat for Persistent Low-Level HIV Viremia

HIV-1-infection | ART | Interleukin | Cd4+ Lymphocyte Deficiency | Lymphoid Tissue; Infection

United States
Tibotec Pharmaceuticals, Ireland

Completed

TMC278-TiDP6-C215: A Clinical Trial in Treatment Naive HIV-subjects Patients Comparing TMC278 to Efavirenz in Combination With 2 Nucleoside/Nucleotide Reverse Transcriptase Inhibitors

HIV Infections | HIV-1

United States, France, United Kingdom, China, Belgium, Germany, Spain, Chile, Mexico, Portugal, Costa Rica, Panama, South Africa, Canada, Brazil, Puerto Rico, Russian Federation, Thailand, Australia, India

Clinical Trials on Organic Cation Transporter 1

Sponsors and Collaborators

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Drug Interventions

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CROs in South Korea

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Rare Diseases

Drug Interventions

Dietary Supplements

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