Clinical Trials on Orotic Aciduria Type 1

Total 4207 results

Maastricht Radiation Oncology
University Medical Center Groningen; Erasmus Medical Center; Leiden University... and other collaborators

Recruiting

Proton Therapy Research Infrastructure- ProTRAIT- Neuro-oncology

Astrocytoma | Adenoma | Ependymoma | Nerve Sheath Neoplasms | Ganglioglioma | Oligodendroglioma | Meningioma | Hemangiopericytoma | Craniopharyngioma | Germinoma | Neurilemmoma | Optic Nerve Glioma

Netherlands
Institut National de la Santé Et de la Recherche...

Recruiting

SEDVasc (RaDiCo Cohort) (RaDiCo-SEDVasc)

Ehlers-Danlos Syndrome, Vascular Type

France
Women and Infants Hospital of Rhode Island

Unknown

The Effect of Neoadjuvant DMPA on Glandular Cellularity in Women Awaiting Hysterectomy

Grade 1 Endometrial Endometrioid Adenocarcinoma | Grade 2 Endometrial Endometrioid Adenocarcinoma | Complex Atypical Endometrial Hyperplasia

United States
M.D. Anderson Cancer Center

Recruiting

Seclidemstat and Azacitidine for the Treatment of Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia

Myelodysplastic Syndrome | Recurrent Chronic Myelomonocytic Leukemia | Recurrent Myelodysplastic Syndrome | Chronic Myelomonocytic Leukemia-1 | Chronic Myelomonocytic Leukemia-2 | Chronic Myelomonocytic Leukemia-0

United States
Massachusetts General Hospital

Completed

Relationship Between Psychosocial Factors, Health Literacy, Quality of Life and Satisfaction With Medical Visits in Adults With NF

Neurofibromatosis

United States
National Cancer Institute (NCI)

Completed

Thalidomide in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Small Lymphocytic Lymphoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Rituximab and Pembrolizumab With or Without Lenalidomide in Treating Patients With Relapsed Follicular Lymphoma and Diffuse Large B-Cell Lymphoma

Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Recurrent Grade 3a Follicular Lymphoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Ultra Low Dose Orbital Radiation Therapy in Treating Patients With Stage I-IV Indolent B-cell Lymphoma or Mantle Cell Lymphoma

Ann Arbor Stage I Grade 1 Follicular Lymphoma | Ann Arbor Stage I Grade 2 Follicular Lymphoma | Ann Arbor Stage II Grade 1 Follicular Lymphoma | Ann Arbor Stage II Grade 2 Follicular Lymphoma | Ann Arbor Stage IV B-Cell Non-Hodgkin Lymphoma | Ann Arbor Stage I B-Cell Non-Hodgkin Lymphoma | Ann... and other conditions

United States
The First Affiliated Hospital of Anhui Medical...

Completed

Evaluation of the Safety of Reoperation for Ipsilateral Recurrent Tumors After Nephron-sparing Partial Nephrectomy (LiangAH)

Renal Cell Carcinoma | Robotic Surgical Procedures
Assistance Publique - Hôpitaux de Paris
Ministry of Health, France

Completed

Angiotensin II Receptor Blockade in Vascular Ehlers Danlos Syndrome (ARCADE) (ARCADE)

Ehlers-Danlos Syndrome, Vascular Type

France
Manchester University NHS Foundation Trust

Completed

Effect of Implant Position on Magnetic Resonance Image Distortion

Neurofibromatosis Type 2

United Kingdom
PTC Therapeutics
United States Department of Defense

Terminated

PTC299 for Treatment of Neurofibromatosis Type 2

Neurofibromatosis 2

United States
National Cancer Institute (NCI)

Completed

Alvocidib, Fludarabine Phosphate, and Rituximab in Treating Patients With Lymphoproliferative Disorders or Mantle Cell Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone Lymphoma | Splenic Marginal Zone Lymphoma | Waldenström Macroglobulinemia and other conditions

United States
Novartis Pharmaceuticals

Recruiting

Pediatric Long-Term Follow-up and Rollover Study

Glioblastoma | Astrocytoma | Anaplastic Astrocytoma | Neurofibromatosis Type 1 | Anaplastic Ganglioglioma | Anaplastic Pleomorphic Xanthoastrocytoma | Ganglioglioma | Pleomorphic Xanthoastrocytoma | Diffuse Astrocytoma | Anaplastic Oligodendroglioma | Pilocytic Astrocytoma | Gangliocytoma | Central Neurocytoma | Oligodendroglioma... and other conditions

United States, Belgium, Spain, Denmark, Germany, Czechia, Italy, Australia, Russian Federation, France, Brazil, Netherlands, Japan, Canada, Finland, Sweden, United Kingdom, Argentina, Israel
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Lenalidomide in Combination With Rituximab in Treating Participants With Stage III/IV Indolent Non-Hodgkin Lymphoma

Ann Arbor Stage III Grade 1 Follicular Lymphoma | Ann Arbor Stage III Grade 2 Follicular Lymphoma | Ann Arbor Stage III Indolent Adult Non-Hodgkin Lymphoma | Ann Arbor Stage IV Grade 1 Follicular Lymphoma | Ann Arbor Stage IV Grade 2 Follicular Lymphoma | Ann Arbor Stage IV Indolent Adult Non-Hodgkin... and other conditions

United States
Cwm Taf University Health Board (NHS)
Cardiff University; Imperial College London; University of Oxford

Completed

Characterisation of the Immune Response to SARS-CoV-2 Infection / COVID-19 in Type 1 Diabetes

Diabetes Mellitus, Type 1 | SARS-CoV2 Infection

United Kingdom
University of Alabama at Birmingham
Medtronic; The Children's Tumor Foundation

Terminated

A Study of INFUSE Bone Graft (BMP-2) in the Treatment of Tibial Pseudarthrosis in Neurofibromatosis Type 1 (NF1) (NF107-BMP2)

NF1 | Congenital Pseudarthrosis of Tibia

United States, Australia
Murdoch Childrens Research Institute

Completed

Clinical Hypnosis and Home Blood Pressure Monitoring in Children With Neurofibromatosis Type 1

Hypertension | Blood Pressure | Neurofibromatosis 1

Australia
University Hospital, Strasbourg, France

Completed

Metabolic Efficiency of Combined Pancreatic Islet and Lung Transplant for the Treatment of End-Stage Cystic Fibrosis (PIM)

Cystic Fibrosis | Insulin-dependent Diabetes | Diabetes Related Cystic Fibrosis

France
Jersey Shore University Medical Center
Rutgers University; Rutgers Cancer Institute of New Jersey

Completed

Genetic Evaluation of Families With Endocrine Cancers (MEN1)

Pancreatic Cancer | Parathyroid Disease | Thymic Cancer | MEN1 Syndrome

United States
OHSU Knight Cancer Institute
National Cancer Institute (NCI); GlaxoSmithKline; Millennium Pharmaceuticals,...

Terminated

Ofatumumab and Bortezomib in Subjects With Relapsed CD20+Diffuse Large B Cell, Follicular, or Mantle Cell Lymphoma

Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma

United States
Massachusetts Eye and Ear Infirmary

Recruiting

Doxycycline in Cutaneous Schwannoma (NF2)

Neurofibromatosis Type 2

United States
National Institute of Neurological Disorders and...

Recruiting

Natural History Study of Patients With Neurofibromatosis Type 2

Neurofibromatosis

United States
Qi Zhou

Not yet recruiting

A Study to Evaluate Dual mTORC1/2 Inhibitor (ATG 008) or Selective Inhibitor of Nuclear Export Compound (ATG-010) in Combination With Chemotherapy in Patients With Relapsed or Metastatic Ovarian Cancer, Endometrial Cancer, and Cervical Cancer ( PORCH ) (PORCH)

1. Relapsed Ovarian Cancer 2. Metastatic Ovarian Cancer 3. Endometrial Cancer 4. Cervical Cancer

China
Children's National Research Institute

Active, not recruiting

Whole Body MRI to Identify Atypical Neurofibromas in Patients With NF1

Neurofibromatosis 1 | Neurofibroma | Plexiform Neurofibroma | Atypical Neurofibroma | Atypical Neurofibromatosis | Von Recklinghausen Disease

United States
Grete Andersen, MD

Completed

Lamotrigine as Treatment of Myotonia

Hyperkalemic Periodic Paralysis | Myotonia Congenita | Paramyotonia Congenita | Dystrophia Myotonica Type 1 | Potassium-Aggravated Myotonia

Denmark
National Cancer Institute (NCI)

Completed

Green Tea Extract in Preventing Cervical Cancer in Patients With Human Papillomavirus and Low-Grade Cervical Intraepithelial Neoplasia

Cervical Cancer | Human Papilloma Virus Infection | Cervical Intraepithelial Neoplasia Grade 1

United States
National Medical Research Center for Therapy and...
Moscow State University of Medicine and Dentistry

Recruiting

Genetic Testing and Motivational Counseling for FH (GENMOTIV-FH)

Medication Adherence | Adherence, Medication | Treatment Adherence | Familial Hypercholesterolemia | Motivational Interviewing | Adherence, Patient | Treatment Adherence and Compliance | Patient Compliance | Adherence | Hypercholesterolemia, Familial | Patient Adherence | Hypercholesterolemia, Autosomal Dominant and other conditions

Russian Federation
National Cancer Institute (NCI)

Active, not recruiting

Anti-ICOS Monoclonal Antibody MEDI-570 in Treating Patients With Relapsed or Refractory Peripheral T-cell Lymphoma Follicular Variant or Angioimmunoblastic T-cell Lymphoma

Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Advanced Primary Cutaneous T-Cell Non-Hodgkin Lymphoma | Recurrent Grade 3a Follicular Lymphoma | Recurrent Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma | Recurrent Mycosis Fungoides | Recurrent Primary Cutaneous... and other conditions

United States, Canada
ImmunoGen, Inc.

Not yet recruiting

A Study of Ocular Toxicity Evaluation and Mitigation During Treatment With Mirvetuximab Soravtansine in Participants With Recurrent Ovarian Cancer With High Folate Receptor-Alpha Expression

Recurrent Ovarian Cancer | Folate Receptor-Alpha Positive

United States, Spain, Australia, Belgium, Canada, France, Ireland, Italy
University of Pennsylvania

Completed

CART19 to Treat B-Cell Leukemia or Lymphoma That Are Resistant or Refractory to Chemotherapy

Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Hematopoietic/Lymphoid Cancer | Adult Acute Lymphoblastic Leukemia in Remission | B-cell Chronic Lymphocytic... and other conditions

United States
Chinese PLA General Hospital

Unknown

Genetically Engineered Lymphocyte Therapy in Treating Patients With Lymphoma That is Resistant or Refractory to Chemotherapy

Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Hematopoietic/Lymphoid Cancer | Adult Acute Lymphoblastic Leukemia in Remission | B-cell Chronic Lymphocytic... and other conditions

China
Chinese PLA General Hospital

Unknown

Treatment of Relapsed and/or Chemotherapy Refractory B-cell Malignancy by Tandem CAR T Cells Targeting CD19 and CD22

Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Hematopoietic/Lymphoid Cancer | Adult Acute Lymphoblastic Leukemia in Remission | Prolymphocytic Leukemia and other conditions

China
Therapeutic Advances in Childhood Leukemia Consortium

Recruiting

A Phase I/II Study of Trametinib and Azacitidine for Patients With Newly Diagnosed Juvenile Myelomonocytic Leukemia

Neurofibromatosis 1 | JMML | Leukemia, Juvenile Myelomonocytic | JCML | CBL Syndrome

United States
Silesian Centre for Heart Diseases
Medical Research Agency, Poland

Not yet recruiting

Sacubitril/Valsartan in PriMAry preventIoN of the Cardiotoxicity of Systematic breaST canceR trEAtMent (MAINSTREAM)

Heart Failure | Breast Cancer | Breast Diseases | Cardiotoxicity | Molecular Mechanisms of Pharmacological Action | Angiotensin Receptor Antagonists | Neoplasm, Breast | Cardiac Toxicity | Angiotensin II Type 1 Receptor Blockers | Cancer, Therapy-Related | Antihypertensive Agents | Sacubitril/Valsartan | Cancer...

Poland
Weill Medical College of Cornell University
National Cancer Institute (NCI); Merck Sharp & Dohme LLC; University of Sao Paulo and other collaborators

Active, not recruiting

Nine-valent HPV Vaccine to Prevent Persistent Oral HPV Infection in Men Living With HIV

HPV Infection | HIV-1-infection | HPV Positive Oropharyngeal Squamous Cell Carcinoma

Brazil, Mexico, Puerto Rico
Lei Li

Recruiting

Genetic Mutation in Epithelial Ovarian Cancer

Epithelial Ovarian Cancer | Microsatellite Instability | PD-L1 | Nucleotide Variant | Copy Number Variation | Insertion-deletion Variation | Genomic Structural Variation | Total Mutation Burden | PD-1

China
National Cancer Institute (NCI)

Withdrawn

Mitogen Activated Protein Kinase Kinase (MEK1/2) Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in People With Neurofibromatosis Type 1 (NF1) Mutated Gastrointestinal Stromal Tumors (GIST)

Neoplasms, Nerve Tissue | Peripheral Nervous System Diseases | Heredodegenerative Disorders, Nervous System | Neurofibromatosis 1
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Active, not recruiting

Polatuzumab Vedotin, Venetoclax, and Rituximab and Hyaluronidase Human for the Treatment of Relapsed or Refractory Mantle Cell Lymphoma

Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone Lymphoma | Refractory B-Cell Non-Hodgkin Lymphoma | Recurrent Small Lymphocytic Lymphoma | Recurrent B-Cell Non-Hodgkin Lymphoma | Recurrent Grade 3a Follicular... and other conditions

United States
University of Alabama at Birmingham
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Phase 2 Clinical Trial of Crizotinib for Children and Adults With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas (NF110)

Neurofibromatosis 2 | Progressive Vestibular Schwannoma (VS)

United States
LMC Diabetes & Endocrinology Ltd.

Completed

Prevalence and Risk Evaluation of Diabetic Complications of the Foot in A Large Canadian Population (PEDAL)

Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1 | Onychomycosis | Foot Deformities | Neuropathy, Diabetic | Foot Ulcer, Diabetic | Hyperkeratosis | Onychauxis

Canada
University of Alabama at Birmingham
Genentech, Inc.

Completed

Phase 2 Study of Bevacizumab in Children and Young Adults With NF 2 and Progressive Vestibular Schwannomas

Neurofibromatosis Type 2 | Progressive Vestibular Schwannomas

United States
University Hospital Tuebingen
National Center for Tumor Diseases, Heidelberg

Completed

WES of NF2-associated in Comparison to Sporadic Vestibular Schwannomas - Correlation With Clinical Data (NF2)

Neurofibromatosis Type 2 | Vestibular Schwannoma | Acoustic Neuroma

Germany
Recursion Pharmaceuticals Inc.

Recruiting

Efficacy and Safety of REC-2282 in Patients With Progressive Neurofibromatosis Type 2 (NF2) Mutated Meningiomas (POPLAR-NF2)

Neurofibromatosis Type 2

United States
Jonsson Comprehensive Cancer Center
Novartis Pharmaceuticals

Terminated

Study of RAD001 for Treatment of NF2-related Vestibular Schwannoma

Neuroma, Acoustic | Neurofibromatosis Type 2

United States
NYU Langone Health

Completed

Study of Axitinib in Patients With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas

Neurofibromatosis Type 2 | Vestibular Schwannomas

United States
Li Peng
Betta Pharmaceuticals Co., Ltd.

Completed

Icotinib Study for Patients With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors (Icotinib)

Neurofibromatosis Type 2 | Vestibular Schwannoma

China
National Institute of Neurological Disorders and...

Completed

Using Positron Emission Tomography to Predict Intracranial Tumor Growth in Neurofibromatosis Type II Patients

Neoplasms | Vestibular Disease | Nervous System Disease

United States
National Cancer Institute (NCI)

Completed

Bevacizumab for Symptomatic Vestibular Schwannoma in Neurofibromatosis Type 2 (NF2)

Neurofibromatosis Type 2 | Vestibular Schwannoma

United States
Beijing Tiantan Hospital
Shandong Simcere-Medgenn Bio-pharmaceutical Co., Ltd

Completed

Endostatin Study for Patients With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors (Endostatin)

Neurofibromatosis Type 2 | Vestibular Schwannoma

China

Clinical Trials on Orotic Aciduria Type 1

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