Clinical Trials on Orthostatic; Hypotension, Parkinsonism in Japan

Total 303 results

Takeshi Morimoto

Terminated

Effect of Intensive Blood Pressure Control on Progression of Coronary Atherosclerosis: Randomized Evaluation by Intravascular Ultrasound (PREVUS)

Coronary Artery Disease | Hypertension

Japan
Eisai Co., Ltd.

Completed

Post-marketing Surveillance of Donepezil Hydrochloride - Investigation of Long Term Safety and Efficacy of Aricept as Well as Its Proper Use Information in Patients With Dementia With Lewy Bodies (DLB).

Dementia With Lewy Body Disease

Japan
Biomedis International Ltd.

Unknown

Recurrent Stroke Prevention Clinical Outcome Study (RESPECTS)

Stroke | Hypertension | Blood Pressure

Japan
Kliniken Beelitz GmbH
Hannover Medical School; University Hospital Muenster; Medical University Innsbruck and other collaborators

Recruiting

Systematic Assessment of Laryngopharyngeal Function in Patients With MSA, PD, and 4repeat Tauopathies (FEEMSA)

Parkinson Disease | Multiple System Atrophy | Progressive Supranuclear Palsy

Germany, Austria, Israel, Italy, Poland, Spain, Japan, Korea, Republic of
Sapporo Health Promotion Foundation

Completed

Efficacy of Exercise at a Fitness Club for Cardiovascular Risk Reduction

Hypertension | Diabetes Mellitus | Hyperlipidemia

Japan
Kagawa University

Unknown

A Prospective Study of the Kidney Protective Effect of Aliskiren in Hypertensive Patients With IgA Nephropathy

Hypertension | Glomerulonephritis, IGA

Japan
Osaka University

Completed

Donepezil Therapy and Changes of Symptoms and Glucose Metabolism in Patients With Dementia With Lewy Bodies (DLB)

Dementia With Lewy Bodies (DLB)

Japan
Jikei University School of Medicine

Unknown

A Morbidity-Mortality and Remodeling Study With Valsartan

Hypertension | Ischemic Heart Disease | Congestive Heart Failure

Japan
Boehringer Ingelheim

Completed

Trial of Telmisartan 80 mg/HCTZ 12.5 mg and Telmisartan 40 mg/HCTZ 12.5 mg in Patients With Hypertension

Hypertension

Japan
Heptares Therapeutics Limited
Sosei

Withdrawn

A Study to Assess Safety, Tolerability, and Efficacy of HTL0018318 in Patients With Dementia With Lewy Bodies (DLB)

Dementia With Lewy Bodies

Japan
Takeda

Completed

A Phase 3 Study of TVP-1012 (1 mg) in Early Parkinson's Disease Patients

Parkinson's Disease

Japan
Kyoto Prefectural University of Medicine

Completed

Add-on Effects of Valsartan on Morbi- Mortality (KYOTO HEART Study)

Stroke | Hypertension | Ischemic Heart Disease | Congestive Heart Failure

Japan
Takeda

Completed

A Phase 3, Long-term, Extension Study of TVP-1012 (1 mg) in Early Parkinson's Disease Participants

Parkinson's Disease

Japan
Takeda

Completed

A Phase 2/3 Study of TVP-1012 at 0.5 mg or 1 mg in Levodopa Treated Parkinson's Disease Participants

Parkinson's Disease

Japan
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Open Label Study of Sildenafil in Patients With Pulmonary Arterial Hypertension

Pulmonary Hypertension

Japan
Novartis Pharmaceuticals

Completed

Safety and Tolerability and Efficacy of LCZ696 in Japanese Severe Hypertensive Patients

Severe Hypertension

Japan
Pfizer

Terminated

Efficacy, Safety and Tolerability of PF-06649751 in Parkinson's Disease Patients With Motor Fluctuations

Parkinson Disease

United States, Spain, Canada, France, Japan, Germany
KVT-Study Group
Yokohama City University; Showa University; Kitasato University; St. Marianna University... and other collaborators

Completed

Kanagawa Valsartan Trial (KVT): Effects of Valsartan on Renal and Cardiovascular Disease

Hypertension | Chronic Kidney Disease

Japan
Nagoya University

Completed

Comparison of Valsartan With Amlodipine in Hypertensive Patients With Glucose Intolerance

Hypertension | Type 2 Diabetes Mellitus

Japan
Janssen Pharmaceutical K.K.

Recruiting

A Study of Macitentan in Japanese Pediatric Participants With Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

Japan
Jichi Medical University
Merck Sharp & Dohme LLC; Satt Co.,Ltd

Completed

To Compare the Effectiveness of Suvorexant vs Placebo on Sleep Pressure in Hypertensives With Insomnia (Super1)

Hypertension | Insomnia

Japan
National Institute of Health and Nutrition

Unknown

Nutrition and Exercise Intervention Study (NEXIS)

Hypertension | Diabetes | Low Back Pain | Dyslipidemia

Japan
Kyorin University

Completed

Submacular Hemorrhage Associated With Retinal Arterial Macro Aneurysm

Submacular Hemorrhage | Ruptured Retinal Arterial Macro Aneurysms

Japan
Novartis Pharmaceuticals

Completed

Pharmacokinetics Following Single-dose of Valsartan in Japanese Pediatric Patients

Hypertension | Chronic Kidney Disease | Nephrotic Syndrome

Japan
Boehringer Ingelheim

Completed

Telmisartan 80mg Non-responder Trial

Hypertension

Japan
Bayer

Completed

High Dose BAYA1040 CR: a Long Term Extension Study

Hypertension

Japan
Genzyme, a Sanofi Company

Terminated

A Global Study to Assess the Drug Dynamics, Efficacy, and Safety of Venglustat (GZ/SAR402671) in Parkinson's Disease Patients Carrying a Glucocerebrosidase (GBA) Gene Mutation (MOVES-PD)

Parkinson's Disease

United States, Austria, Canada, France, Germany, Greece, Israel, Italy, Japan, Norway, Portugal, Singapore, Spain, Sweden, Taiwan, United Kingdom
Bayer

Completed

Post-marketing Surveillance for Hypertensive Patients With Diabetes and/or Chronic Kidney Disease

Hypertension

Japan
Jichi Medical University
Eli Lilly and Company; Boehringer Ingelheim

Completed

SGLT-2i and ARB Combination Therapy in Patients With T2DM and Nocturnal Hypertension (SACRA Study)

T2DM (Type 2 Diabetes Mellitus) | Nocturnal Hypertension

Japan
Actelion
EPS Corporation; Imepro Inc.; General Laboratory, BML, Inc.; Mitsubishi Logistics...

Terminated

A Clinical Study to Find Out if Macitentan is Effective and Safe in Japanese Patients With Chronic Thromboembolic Pulmonary Hypertension (CTEPH).

Chronic Thromboembolic Pulmonary Hypertension (CTEPH)

Japan
Novartis

Completed

Evaluation of the Efficacy and Safety of AFQ056 in Reducing Moderate to Severe L-dopa Induced Dyskinesias in Patients With Parkinson's Disease

Parkinson Disease | Dyskinesias

Italy, Spain, France, Germany, Finland, Japan, Australia, Canada
Bayer

Completed

High Dose BAYA1040_Nifedipine: a Dose-comparative Study

Hypertension

Japan
Boehringer Ingelheim

Completed

Special Survey on Parkinson's Disease (PD) Patients Without Concomitant Use of L-Dopa

Parkinson Disease

Japan
Advanced-J
Japan Heart Foundation

Unknown

A Study on Ca Blocker Versus AII Antagonists in Hypertension With Type 2 Diabetes

Hypertension | Diabetes Mellitus, Type 2

Japan
Nagoya University

Unknown

Investigation of Genetic Risk of Metabolic Syndrome in Company Employee (NGK Study)

Hypertension | Healthy | Diabetes Mellitus | Hyperlipidemia | Metabolic Syndrome X

Japan
Merck Sharp & Dohme LLC

Active, not recruiting

A Study of Sotatercept in Japanese Pulmonary Arterial Hypertension (PAH) Participants (MK-7962-020)

Pulmonary Arterial Hypertension

Japan
Shiga University

Unknown

Rationale and Design for Shiga Microalbuminuria Reduction Trial

Hypertension | Diabetes Mellitus | Albuminuria

Japan
Boehringer Ingelheim

Completed

Filtered Trial for Telmisartan 40mg Non-responder

Hypertension

Japan
Kyorin University

Completed

Macular Retinoschisis and Detachment Associated With Glaucomatous Optic Neuropathy

Normal Tension Glaucoma | Macular Retinoschisis | Macular Detachment

Japan
Nara Medical University

Completed

Angiotensin II Receptor Blockers (ARB) and ACE Inhibitors (ACEI) on Silent Brain Infarction and Cognitive Decline

Hypertension | Brain Infarction

Japan
Novartis Pharmaceuticals

Completed

Long Term Safety of SPA100 (Fixed-dose Combination of Aliskiren/Amlodipine) in Patients With Essential Hypertension

Essential Hypertension

Japan
Boehringer Ingelheim

Completed

Long-term Safety Study of Open-label Pramipexole Extended Release (ER) in Patients With Early Parkinson´s Disease (PD).

Parkinson Disease

United States, Austria, Czech Republic, Finland, France, Germany, Hungary, India, Japan, Malaysia, Netherlands, Russian Federation, Slovakia, Taiwan, Ukraine
Boehringer Ingelheim

Completed

Study of (Mirapex) Pramipexole for the Early Treatment of Parkinsons Disease (PD)

Parkinson Disease

United States, Austria, Finland, France, Germany, Italy, Japan, Spain, Sweden, United Kingdom
Shiga University

Completed

Shiga Microalbuminuria Reduction Trial-2

Hypertension | Type 2 Diabetes Mellitus

Japan
HeadSense Medical

Suspended

An Evaluation of Non-Invasive ICP Monitoring in Patients Undergoing Invasive ICP Monitoring Via an Intraparenchymal Pressure Monitoring Device

Stroke | Brain Injuries | Brain Neoplasms | Intracranial Hypertension | Hydrocephalus

Japan
Dokkyo Medical University

Completed

Effect of Pioglitazone on Cardiovascular Outcome on Higashi-Saitama Trial in Patients With Type 2 Diabetes

Hypertension | Diabetic Nephropathy | Type 2 Diabetes | Dyslipidemia

Japan
Bausch & Lomb Incorporated

Completed

A Phase 2, Dose Finding Study of PF-03187207 in Patients With Primary Open Angle Glaucoma or Ocular Hypertension.

Primary Open Angle Glaucoma | Ocular Hypertension

Japan
Kyoto University, Graduate School of Medicine

Completed

Effects of Antihypertensive Drugs in Patients With Hypertension and Obstructive Sleep Apnea (OSA)

Hypertension | Obstructive Sleep Apnea

Japan
Pfizer

Completed

Long Term Study Of Amlodipine 10mg With Hypertension For Whom Amlodipine 5mg Is Insufficient

Hypertension

Japan
Boehringer Ingelheim

Completed

Safety and Efficacy of Long-term Daily Use of Mirapex®-LA Tablets in Patients With Parkinson's Disease

Parkinson Disease

Japan

Clinical Trials on Orthostatic; Hypotension, Parkinsonism in Japan

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