Clinical Trials on POOR PROGNOSIS

Total 550 results

University of L'Aquila

Completed

Prognostic Score in Covid-19

Covid19 Prognostic Parameters

Italy
Kanuni Sultan Suleyman Training and Research Hospital

Completed

Prognosis in Pregnant With COVID-19

COVID-19 | Pregnancy | Prognostic Factors

Turkey
Ottawa Hospital Research Institute
University of Toronto; University of Western Ontario, Canada; University of Ottawa

Active, not recruiting

Adverse Long-term Consequences of Sleep Disordered Breathing: The Ottawa Hospital (TOH) Sleep Database

Sleep Apnea Syndromes | Restless Legs Syndrome | Opioid Use | Risk Factors | Prognosis | Periodic Limb Movement Sleep Disorder | Polysomnography | Sleep Arousal Disorders

Canada
University Hospital, Montpellier
Thermo Fisher Scientific, Inc

Completed

Prediction of Inflammatory Response and Hypotensive Syndrome After Cardiac Surgery by Preoperative Copeptin Level (MicorSIRS)

Stress Response | Systemic Inflammatory Response Syndrome (SIRS) | Postoperative Vasodilation Syndrome | Cardiac Surgery Prognosis | Tissue Oxygenation and Post-ischemic Response

France
Centre Hospitalier Universitaire, Amiens

Recruiting

French Single Centre Experience of Critically Ill Patients With Covid 19 (CovidAmiens20)

COVID 19 | Critical Care | Sars-CoV2 | Survival | Epidemiology | Prognostic

France
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Ipatasertib in Combination With Carboplatin, Carboplatin/Paclitaxel, or Capecitabine/Atezolizumab in Treating Patients With Metastatic Triple Negative Breast Cancer

Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Metastatic Triple-Negative Breast Carcinoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

M7824 and Eribulin Mesylate in Treating Patients With Metastatic Triple Negative Breast Cancer

Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Metastatic Triple-Negative Breast Carcinoma

United States
University Hospital, Limoges

Completed

Medullary Colonic Carcinoma (MEDCCR)

Prognostic Factors | Survival Analysis | Medullary Carcinoma of Colon

France
National Cancer Institute (NCI)

Withdrawn

A Study of a New Drug Combination, Copanlisib and Fulvestrant, in Advanced Breast Cancer

Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Brain | Metastatic Breast Carcinoma

United States
University Hospital, Lille

Completed

Prognosis of Signet Ring Cells in Upper Digestive Neoplasms (ADCI001)

Case-control Study | Stomach Disease | Signet Ring Cell Carcinoma | Oesophagus | Prognostic

France
Lei Li

Recruiting

ctDNA Methylation for Detecting Ovarian Cancer

Epithelial Ovarian Cancer | Circulating Tumor DNA | CA125 | DNA Methylation | Non-invasive Diagnosis | Human Epididymis Protein 4 | Imaging Evaluation | Survival Prognosis | ROMA Index

China
Aspire Nutrition, LLP

Not yet recruiting

Impact of Mindfulness Program on Perceived Wellness, Eating Habits and Relationship to Food

Nutrition Disorders | Mental Fatigue | Dietary Habits | Diet, Healthy | Eating Disorders | Eating Behavior | Food Habits | Mental Stress | Nutrition Poor | Mental Health Issue | Nutrition, Healthy | Eating, Compulsive | Eating Disorder Weight Fixation
PAVmed Inc.

Active, not recruiting

PR-0164 First in Human Clinical Trial of the PAVmed PortIO Intraosseous Infusion System

Chronic Kidney Disease Stage 5 | Chronic Kidney Disease stage4 | Chronic Kidney Disease stage3 | Poor Vascular Access

Colombia
University of Florida
Mayo Clinic; Florida Department of Health; Tallahassee Memorial HealthCare

Terminated

Physical Exercise And Cognitive Engagement Outcomes for Mild Neurocognitive Disorder (PEACEOFMND)

Mild Cognitive Impairment | Memory Disorders | Memory Impairment | Impaired Cognition | Mild Dementia | Mild Cognitive Disorder | Mild Neurocognitive Disorder | Amnestic Disorder | Dementia and Amnestic Conditions | Poor Short-term Memory

United States
University of North Carolina, Chapel Hill
3M ESPE

Terminated

Clinical Investigation of a New Bulk Fill Composite Resin in the Restoration of Posterior Teeth

Dental Caries | Dental Restoration Failure of Marginal Integrity | Unrepairable Overhanging of Dental Restorative Materials | Poor Aesthetics of Existing Restoration | Secondary Dental Caries Associated With Failed or Defective Dental Restorations | Fractured Dental Restorative Materials Without... and other conditions

United States
Lei Li

Completed

A Study on Association Between HR Genes and the HRD Status in Chinese Epithelial Ovarian Cancer

Epithelial Ovarian Cancer | BRCA1 Mutation | BRCA2 Mutation | Homologous Recombination Deficiency | Prognosis | Chinese | Homologous Recombination Genes

China
Assiut University

Not yet recruiting

The Prognostic Impact Of The Neutrophil To Lymphocyte Ratio In Patients With Locally Advanced Rectal Cancer

the Prognostic Value of Pre-treatment NLR in Patients With Locally Advenced Rectal Cancer and Post-treatment
University Hospital, Ghent
Universitaire Ziekenhuizen KU Leuven; University Hospital, Antwerp; Cliniques...

Recruiting

Serum Glycomics as Prognostic and Diagnostic Biomarkers of Disease Recurrence in Liver Transplant Recipients With Hepatocellular Carcinoma (GLITCA)

Liver Transplantation | Hepatocellular Carcinoma | Prognostic Biomarker | Diagnostic Biomarker

Belgium
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Letrozole and Imatinib Mesylate in Treating Postmenopausal Participants With Estrogen or Progesterone Positive Metastatic Breast Cancer

Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Estrogen Receptor Positive | Progesterone Receptor Positive | Postmenopausal | KIT Positive | PDGFR Positive

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Abemaciclib and Endocrine Therapy in Older Patients With Breast Cancer.

Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Hormone Receptor Positive Breast Carcinoma | Metastatic Breast Carcinoma

United States
City of Hope Medical Center
National Cancer Institute (NCI); Imugene Limited

Active, not recruiting

CF33-hNIS-antiPDL1 for the Treatment of Metastatic Triple Negative Breast Cancer

Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Metastatic Triple-Negative Breast Carcinoma

United States
Universidade do Porto

Completed

Early Multimodal Neuromonitoring For Spontaneous Intracerebral Hemorrhage (ICH)

Critically Ill | Intracerebral Hemorrhage | Intracranial Pressure | Cerebral Perfusion Pressure | Prognostic

Portugal
Mayo Clinic
Patient-Centered Outcomes Research Institute

Completed

Behavioral Interventions to Prevent or Delay Dementia

Mild Cognitive Impairment | Memory Disorders | Memory Impairment | Impaired Cognition | Mild Dementia | Mild Cognitive Disorder | Amnestic Disorder | Dementia and Amnestic Conditions | Poor Short-term Memory

United States
Lei Li

Recruiting

ctDNA Methylation for Epithelial Ovarian Cancer

Epithelial Ovarian Cancer | Circulating Tumor DNA | CA125 | DNA Methylation | Non-invasive Diagnosis | Human Epididymis Protein 4 | Imaging Evaluation | Survival Prognosis

China
University Hospital, Clermont-Ferrand
M2iSH laboratory; Benoit Chassaing

Unknown

Predictive Value of Innovative Prognostic Markers (Gut Microbiota, Sarcopenia, Metabolic Syndrome and Obesity) on Surgical and Oncologic Results in the Management of Sporadic Colorectal Adenocarcinoma. (METABIOTE)

Colorectal Neoplasms | Metabolic Syndrome | Sarcopenia | Microbiota | Prognosis

France
Lei Li

Unknown

Non-coding RNA in the Exosome of the Epithelia Ovarian Cancer

Ovarian Cancer | High Grade Serous Carcinoma | Prognosis | Early Diagnosis | Exosomes

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Sun Yat-sen University; The Third Affiliated Hospital of Guangzhou Medical... and other collaborators

Recruiting

AI-Assisted System for Accurate Diagnosis and Prognosis of Breast Phyllodes Tumors

Artificial Intelligence | Diagnosis | Phyllodes Breast Tumor | Multiomics | Prognostic Cancer Model

China
Pamela Munster
Pfizer; Xynomic Pharmaceuticals, Inc.

Withdrawn

Abexinostat, Palbociclib, and Fulvestrant for the Treatment of Breast or Gynecologic Cancer

Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 | Anatomic Stage IIIC Breast Cancer AJCC v8 | Prognostic Stage III Breast Cancer AJCC v8 | Prognostic Stage IIIA Breast Cancer AJCC v8 | Prognostic Stage IIIB Breast... and other conditions
Emory University
National Cancer Institute (NCI); Pfizer; National Institutes of Health (NIH)

Completed

Radiation Therapy, Palbociclib, and Hormone Therapy in Treating Breast Cancer Patients With Bone Metastasis (ASPIRE)

Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Bone | Estrogen Receptor Positive | HER2/Neu Negative | Progesterone Receptor Positive | Metastatic Breast Carcinoma

United States
Thomas Jefferson University

Withdrawn

Breast Cancer Vaccine in Combination With Pembrolizumab for Treatment of Persistent, Recurrent, or Metastatic Breast Cancer

Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Recurrent Breast Carcinoma | Metastatic Breast Carcinoma | Refractory Breast Carcinoma

United States
OHSU Knight Cancer Institute
Oregon Health and Science University; Prospect Creek Foundation

Completed

Olaparib and Durvalumab in Treating Participants With Metastatic Triple Negative Breast Cancer

Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Estrogen Receptor Negative | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative Breast Carcinoma

United States
SWOG Cancer Research Network
National Cancer Institute (NCI)

Recruiting

S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer

Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Estrogen Receptor Positive | HER2/Neu Negative | Progesterone Receptor Positive | Elevated CA15-3 or CEA or CA27-29

United States, Puerto Rico, Guam
Emory University
National Cancer Institute (NCI); Sirtex Medical

Withdrawn

Radioembolization of Metastatic Breast Cancer to the Liver as a 2nd/3rd Line Therapy

Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Metastatic Breast Carcinoma | Metastatic Carcinoma in the Liver

United States
Guangxi Medical University
Guilin Medical College; Second Affiliated Hospital of Guangzhou Medical University and other collaborators

Unknown

Retrospective Analysis of the Epidemiological Change and Determinants of Prognosis of Talaromycosisof Human Immunodeficiency Virus Negative Host in Guangxi (RAECDPT)

To Investigate the Characteristics and Prognostic Factors of T. Marneffei Infections and the Causes of Misdiagnosis | To Study the Recurrence Indicators and Establish a Therapeutic Effect Evaluation System of T. Marneffei Infections

China
Fujian Cancer Hospital

Not yet recruiting

MRI-based Signatures for Survival Prediction in Cervical Cancer With Radiotherapy

MRI | Cervical Cancer | Radiotherapy | Prognostic Model

China
Centre Hospitalier Universitaire, Amiens
Centre Henri Becquerel; Hôpital Jeanne de Flandre LIlle

Recruiting

Evaluation of Optical Genome Mapping in Phi Negative Myeloproliferative Neoplasia in the Detection of Acquired Cytogenetic Abnormalities (MYELOCARTOCH)

Myeloproliferative Neoplasm | Optical Genome Mapping | Cytogenetics | Clonality | Prognostic Stratification

France
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Active, not recruiting

Using FDG-PET/CT to Assess Response of Bone-Dominant Metastatic Breast Cancer, FEATURE Study

Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Hormone Receptor Positive Breast Carcinoma | Metastatic Breast Carcinoma

United States, Puerto Rico, Ireland
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Withdrawn

T-DM1 With or Without Abemaciclib for the Treatment of HER2-Positive Metastatic Breast Cancer

Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | HER2 Positive Breast Carcinoma | Metastatic Breast Carcinoma

United States
University of Texas Southwestern Medical Center

Completed

Prospective Registry Trial for Single Port Robot-assisted Nipple Sparing Mastectomy (SPrNSM) (SPrNSM)

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Prognostic... and other conditions

United States
University Hospital, Bordeaux

Recruiting

Treatment Pause Versus Treatment Continuation in IMDC Good or Intermediate Risk With Only One Adverse Prognostic Factor in mRCC Patients With an Objective Response at 12 Months of Treatment With PD1/ PDL1 ICIs + VEGFR-Tyrosine Kinase Inhibitors (SPICI)

Metastatic Renal Cell Carcinoma | Good or Only One Adverse Prognostic Factor Intermediate Risk Per IMDC Score

France
Lassen Therapeutics Inc.

Recruiting

A Study to Evaluate the Efficacy and Safety of LASN01 in Patients With Thyroid Eye Disease

Eye Diseases | Endocrine System Diseases | Thyroid Eye Disease | Graves Ophthalmopathy | Orbital Diseases | Thyroid Associated Ophthalmopathy | Graves Orbitopathy | Proptosis

United States, United Kingdom, Spain
OHSU Knight Cancer Institute
Novartis; Oregon Health and Science University

Not yet recruiting

177Lu-DOTATATE for the Treatment of Stage IV or Recurrent Breast Cancer

Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Recurrent Breast Carcinoma | Metastatic Breast Carcinoma

United States
Louisiana State University Health Sciences Center...

Completed

Asthma and Obesity Diet Versus Exercise

Physical Activity | Metabolic Syndrome | Inflammatory Response | Asthma in Children | Obesity, Childhood | Nutrition Poor | Behavior, Eating | Maternal Exposure | Molecular Biology, Restriction Fragment Length Polymorphisms | Genetic Change

United States
Roswell Park Cancer Institute
Pfizer

Completed

Breast Cancer Pathways Program Impact on Patient Shared Decision Making and Experience in Academic and Community Practice

Breast Carcinoma | Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Recurrent Breast Carcinoma | Metastatic Breast Carcinoma

United States
Hospices Civils de Lyon

Unknown

Interest of the Dosage of Ferritin / Glycosylated Ferritin in COVID-19

the Prognostic Value of Ferritin | Glycosylated Ferritin in SARS-CoV-2 Infection in Hospitalized COVID-19 Patients

France
M.D. Anderson Cancer Center

Withdrawn

Immunotherapy (NHS-IL12 & Bintrafusp Alfa) and Radiation Therapy for the Treatment of Hormone Receptor Positive, HER2 Negative Metastatic Breast Cancer, the REINA Trial

Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Metastatic Breast Carcinoma | Hormone Receptor Positive Breast Adenocarcinoma | Metastatic HER2 Negative Breast Adenocarcinoma

United States
Emory University
National Cancer Institute (NCI); National Institutes of Health (NIH)

Active, not recruiting

Fluciclovine and PSMA PET/CT for the Classification and Improved Staging of Invasive Lobular Breast Cancer

Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Invasive Breast Lobular Carcinoma | Metastatic Breast Lobular Carcinoma

United States
Sling Therapeutics, Inc.

Recruiting

A Phase 2b Extension Study of Two Doses of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)

Eye Diseases | Endocrine System Diseases | Thyroid Diseases | Thyroid Eye Disease | Graves Ophthalmopathy | Exophthalmos | Orbital Diseases | Thyroid Associated Ophthalmopathy | Graves Orbitopathy | Proptosis | IGF1R | Hashimoto

United States
Sling Therapeutics, Inc.

Recruiting

A Phase 2b, Study of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED) (LIDS)

Eye Diseases | Endocrine System Diseases | Thyroid Diseases | Thyroid Eye Disease | Graves Ophthalmopathy | Exophthalmos | Orbital Diseases | Thyroid Associated Ophthalmopathy | Graves Orbitopathy | Proptosis | IGF1R | Hashimoto

United States, Spain, Canada, Italy, United Kingdom
Northwestern University
National Cancer Institute (NCI)

Withdrawn

SGT-53, Carboplatin, and Pembrolizumab for the Treatment of Metastatic Triple Negative Inflammatory Breast Cancer

Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Metastatic Triple-Negative Breast Carcinoma | Breast Inflammatory Carcinoma

United States

Clinical Trials on POOR PROGNOSIS

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Panama

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations