Clinical Trials on Pancreatic Beta Cell Adenoma

Total 953 results

Academic and Community Cancer Research United
National Cancer Institute (NCI)

Withdrawn

Dovitinib Lactate in Treating Patients With Pancreatic Neuroendocrine Tumors

Gastrinoma | Glucagonoma | Insulinoma | Pancreatic Polypeptide Tumor | Recurrent Islet Cell Carcinoma | Somatostatinoma
Changhai Hospital

Completed

Real-world Study on Adjuvant Octreotide Therapy in pNETs

Pancreatic Neuroendocrine Tumor G2
Dana-Farber Cancer Institute
Massachusetts General Hospital; Brigham and Women's Hospital; Amgen; H. Lee Moffitt...

Completed

AMG 479 in Advanced Carcinoid and Pancreatic Neuroendocrine Tumors

Neuroendocrine Tumor | Carcinoid Tumor | Pancreatic Neuroendocrine Tumor

United States
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Active, not recruiting

Temozolomide With or Without Capecitabine in Treating Patients With Advanced Pancreatic Neuroendocrine Tumors

Gastrinoma | Glucagonoma | Insulinoma | Pancreatic Polypeptide Tumor | Recurrent Islet Cell Carcinoma | Somatostatinoma | Islet Cell Carcinoma

United States
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Terminated

Everolimus in Patients With Pancreatic Neuroendocrine Tumors Metastatic to the Liver Previously Treated With Surgery

Liver Metastases | Gastrinoma | Glucagonoma | Insulinoma | Pancreatic Polypeptide Tumor | Recurrent Islet Cell Carcinoma | Somatostatinoma

United States
Asan Medical Center
Novartis

Unknown

Clinical Effectiveness of Serum Chromogranin A Levels on Diagnostic of Pancreatic Neuroendocrine Tumors (CgA)

Non Functioning Pancreatic Endocrine Tumor
Peking Union Medical College Hospital

Active, not recruiting

[68Ga]Ga-HBED-CC-exendin-4 and [68Ga]Ga-NOTA-exendin-4 PET/CT Imaging in the Same Group of Insulinoma Patients

Insulinoma

China
Guangxi Medical University

Unknown

EUS-guided Ethanol Ablation of an Insulinoma (EUS)

Insulinoma

China
Radboud University Medical Center
Charite University, Berlin, Germany; University of Turku; University Medical... and other collaborators

Completed

68Ga-NODAGA-exendin-4 PET/CT for Diagnostic Imaging in AHH (GLP-1-AHH)

Insulinoma
Peking Union Medical College Hospital
Peking University First Hospital; First Affiliated Hospital Xi'an Jiaotong... and other collaborators

Recruiting

A Multi-center Study to Evaluate the Efficacy and Safety of Pancreatic Duct Stents Placement Before the Enucleation of Insulinoma Located in the Head and Neck of the Pancreas Near the Main Pancreatic Duct

Insulinoma

China
First Affiliated Hospital of Fujian Medical University

Recruiting

The Clinical Application of 68Ga-NOTA-exendin-4 PET/CT in Detecting Insulinoma

Insulinoma

China
Nanjing First Hospital, Nanjing Medical University

Unknown

Clinical Evaluation of 68Ga-NOTA-MAL-Cys39-exendin-4 Positron Emission Tomography in the Detection of Insulinoma

Insulinoma

China
Medical University of Vienna

Not yet recruiting

Non-functioning Pancreatic Neuroendocrine Tumors in MEN1: Somatostatin Analogs Versus NO Treatment (SANO)

Pancreatic Neuroendocrine Tumors in MEN1
H. Lee Moffitt Cancer Center and Research Institute
Pfizer

Completed

Phase II Study of Sunitinib Malate Following Hepatic Artery Embolization

Neuroendocrine Tumor | Islet Cell Tumor

United States
Vishnevsky Center of Surgery

Completed

Blinded Resection in Case of the Pancreatic Insulinoma

Insulinoma; Pancreas
SWOG Cancer Research Network
National Cancer Institute (NCI)

Recruiting

Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine Tumors

Pancreatic Neuroendocrine Tumor | Metastatic Malignant Neoplasm in the Liver | Stage I Pancreatic Neuroendocrine Tumor AJCC v8 | Stage II Pancreatic Neuroendocrine Tumor AJCC v8 | Stage III Pancreatic Neuroendocrine Tumor AJCC v8

United States
National Heart, Lung, and Blood Institute (NHLBI)

Enrolling by invitation

Investigating the Mechanistic Effects of Mitapivat in Subjects With Sickle Cell Disease

Sickle Cell Anemia | Sickle Beta Thalassemia | Sickle Cell Thalassemia | Sickle Beta Zero Thalassemia | Sickle Cell Pain | Hbss | Hbsc | Sickle Cell Syndrome Variant

United States
National Institute of Diabetes and Digestive and...

Completed

Laparoscopy to Remove Pancreatic Tumors (Insulinomas)

Insulinoma

United States
Vertex Pharmaceuticals Incorporated
CRISPR Therapeutics

Recruiting

Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease

Hematologic Diseases | Genetic Diseases, Inborn | Sickle Cell Disease | Hemoglobinopathies | Sickle Cell Anemia | Thalassemia | Beta-Thalassemia

United States, Italy, Germany, Saudi Arabia
University of California, San Francisco
University of California Pancreatic Cancer Consortium (UCPCC)

Recruiting

Genetic Predisposition Testing Program for Pancreatic Neuroendocrine Neoplasms (PanNEN)

Pancreatic Neuroendocrine Neoplasm

United States
Vertex Pharmaceuticals Incorporated
CRISPR Therapeutics

Enrolling by invitation

A Long-term Follow-up Study in Participants Who Received CTX001

Hematologic Diseases | Genetic Diseases, Inborn | Sickle Cell Disease | Hemoglobinopathies | Sickle Cell Anemia | Thalassemia | Beta-Thalassemia

United States, Canada, Italy, United Kingdom, Germany
Aadi Bioscience, Inc.

Recruiting

Trial of Nab-sirolimus in Patients With Well-differentiated Neuroendocrine Tumors (NETs) of the Gastrointestinal Tract, Lung, or Pancreas Who Have Not Received Prior Treatment With mTOR Inhibitors

Neuroendocrine Tumors | Pancreatic Neuroendocrine Tumor | Gastrointestinal Neuroendocrine Tumor | NET | Pulmonary Neuroendocrine Tumor

United States
National Institute of Diabetes and Digestive and...

Completed

Interferon and Octreotide to Treat Zollinger-Ellison Syndrome and Advanced Non-B Islet Cell Cancer

Zollinger Ellison Syndrome | Islet Cell Adenoma

United States
Kenneth Ataga, MD
Augusta University

Completed

Hepcidin Levels in Sickle Cell Disease (SCD)

Sickle Cell Anemia | Sickle - Beta Thalassemia
National Institute of Diabetes and Digestive and...

Recruiting

Diagnosing and Treating Low Blood Sugar Levels

Hypoglycemia | Insulinoma

United States
University Hospital, Basel, Switzerland

Completed

Whole Body 111In-exendin-4 Imaging Study in Insulinoma Patients

Hypoglycemia | Hyperinsulinism | Insulinoma

Switzerland
Nova Laboratories Limited

Completed

Pharmacokinetics of Oral Hydroxyurea Solution (HUPK)

Sickle Cell Disease | Sickle Cell Hemoglobin C | Sickle Cell-beta-thalassemia | Sickle-Cell; Hemoglobin Disease, Thalassemia

United Kingdom, Jamaica
National Institute of Diabetes and Digestive and...

Completed

Combination Chemotherapy in Patients With Zollinger-Ellison Syndrome and Tumors of the Pancreas

Neoplasm Metastasis | Zollinger Ellison Syndrome | Islet Cell Adenoma

United States
Ochsner Health System

Unknown

68Ga-DOTATATE PET Scan Imaging in Patients With Neuroendocrine Tumors

Neuroendocrine Tumor | Neuroendocrine Carcinoma | Carcinoid Tumor | Neuroendocrine Cancer | Carcinoid | Islet Cell Tumor | Neuroendocrine | Apudoma

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cord Blood Transplantation for Sickle Cell Anemia and Thalassemia

Hematologic Diseases | Anemia, Sickle Cell | Beta-Thalassemia | Hematopoietic Stem Cell Transplantation

United States, Canada
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

Study to Evaluate the Safety and Tolerability of Escalating Doses of Fostamatinib in Subjects With Stable Sickle Cell Disease

Sickle Cell Disease | Sickle Cell Disorders | Hb-SS Disease | Hemoglobin S | Disease Sickle Cell Anemia | Hemoglobin Beta Thalassemia Disease

United States
Phoenicia BioScience
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

The BENeFiTS Trial in Beta Thalassemia Intermedia (PB04-001)

Sickle Cell Disease | Beta Thalassemia Intermedia

United States, Canada
Northwell Health

Completed

HSCT For Patients With High Risk Hemoglobinopathies Using Reduced Intensity

Sickle Cell Disease | Beta Thalassemia-Major

United States
Editas Medicine, Inc.

Not yet recruiting

A Long-Term Follow-Up Study of Participants With Sickle Cell Disease or Transfusion Dependent β-Thalassemia Who Received EDIT-301

Sickle Cell Disease | Hemoglobinopathies | Transfusion-dependent Beta-Thalassemia
University Health Network, Toronto

Completed

Mechanism of Fatty Acid-Induced Impairment of Glucose-Stimulated Insulin Secretion

Insulin Resistance Syndrome X | Pancreatic Beta Cell Function

Canada
Emory University
Patient-Centered Outcomes Research Institute

Completed

Decision Aid for Therapeutic Options In Sickle Cell Disease

Sickle Cell Disease | Sickle Cell Anemia | Hemoglobin SC | Hemoglobin SS | Hemoglobin Beta Thalassemia

United States
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Terminated

Internal Radiation Therapy in Treating Patients With Liver Metastases From Neuroendocrine Tumors

Head and Neck Cancer | Metastatic Cancer | Pheochromocytoma | Islet Cell Tumor

United States
British Columbia Cancer Agency

Withdrawn

177Lu-DOTATOC for the Treatment of Patients With Somatostatin Receptor Positive NETs

Neuroendocrine Tumors | Carcinoid Tumor | Gastrinoma | Insulinoma | Vipoma | Gastroenteropancreatic Neuroendocrine Tumor | Pulmonary Carcinoid Tumor

Canada
University Medical Center Groningen

Completed

Biomarkers for Angiogenesis in Renal Cell Carcinoma and Neuro-endocrine Tumours. (BANN)

Carcinoma, Renal Cell | Carcinoma | Neuroendocrine Tumors | Carcinoid Tumor | Pancreatic Islet Cell Tumors

Netherlands
Guangxi Medical University

Recruiting

EUS-FNI for MEN1-related Pancreatic Neuroendocrine Tumors

Pancreatic Neuroendocrine Tumor | Multiple Endocrine Neoplasia Type 1

China
Vanderbilt-Ingram Cancer Center

Recruiting

Surgical Debulking Prior to Peptide Receptor Radionuclide Therapy in Well Differentiated Gastroenteropancreatic Neuroendocrine Tumors

Metastatic Digestive System Neuroendocrine Neoplasm | Metastatic Malignant Neoplasm in the Liver | Pancreatic Neuroendocrine Tumor G1 | Pancreatic Neuroendocrine Tumor G2 | Digestive System Neuroendocrine Tumor G1 | Digestive System Neuroendocrine Tumor G2

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Novartis

Completed

Ribociclib in Treating Patients With Advanced Neuroendocrine Tumors of Foregut Origin

Intermediate Grade Lung Neuroendocrine Neoplasm | Low Grade Lung Neuroendocrine Neoplasm | Functional Pancreatic Neuroendocrine Tumor | Advanced Digestive System Neuroendocrine Neoplasm | Duodenal Neuroendocrine Tumor G1 | Gastric Neuroendocrine Tumor | Nonfunctional Pancreatic Neuroendocrine... and other conditions

United States
National Institutes of Health Clinical Center (CC)
National Cancer Institute (NCI)

Completed

Isolated Hepatic Perfusion With Melphalan in Treating Patients With Primary Unresectable Liver Cancer or Liver Metastases

Colorectal Cancer | Metastatic Cancer | Liver Cancer | Neuroendocrine Carcinoma | Islet Cell Tumor

United States
Kyunghee University Medical Center
Sanofi; Korea University Guro Hospital; Hanyang University; The Catholic University... and other collaborators

Completed

Study To Evaluate Beta Cell Function and Glycemic Outcome by Intensive Insulin Therapy (KIIT)

Type 2 Diabetes Mellitus | Pancreatic Beta Cell Function | Glucotoxicity

Korea, Republic of
National Cancer Institute (NCI)

Completed

Temsirolimus and Bevacizumab in Treating Patients With Advanced Endometrial, Ovarian, Liver, Carcinoid, or Islet Cell Cancer

Uterine Carcinosarcoma | Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Recurrent Uterine Corpus Carcinoma | Ovarian Endometrioid Adenocarcinoma | Ovarian Seromucinous Carcinoma | Endometrial Serous Adenocarcinoma | Lung Carcinoid Tumor | Metastatic... and other conditions

United States, Canada
Hillel Yaffe Medical Center

Unknown

Prevalence Of Microalbuminuria Among Children Suffering From Sickle Cell Nephropathy and Sickle Cell/Beta-Thalassemia

Sickle Cell Anemia | Beta-Thalassemia | Microalbuminuria
University of Southern California
National Cancer Institute (NCI)

Completed

Regorafenib in Treating Patients With Advanced or Metastatic Neuroendocrine Tumors

Gastrinoma | Glucagonoma | Insulinoma | Metastatic Gastrointestinal Carcinoid Tumor | Pancreatic Polypeptide Tumor | Recurrent Gastrointestinal Carcinoid Tumor | Recurrent Islet Cell Carcinoma | Somatostatinoma | Pulmonary Carcinoid Tumor

United States
M.D. Anderson Cancer Center

Recruiting

Metabolomics and Genetic Diagnosing Pancreatic Neuroendocrine Tumors in MEN1 Patients

Multiple Endocrine Neoplasia

United States
Threshold Pharmaceuticals

Unknown

Dose-Escalation Study of TH-302 in Combination With Sunitinib to Treat Patients With Advanced Renal Cell Carcinoma,Gastrointestinal Stromal Tumors and Pancreatic Neuroendocrine Tumors (TH-CR-410)

Gastrointestinal Stromal Tumors | Advanced Renal Cell Carcinoma | Pancreatic Neuroendocrine Tumors

United States
M.D. Anderson Cancer Center

Recruiting

Variables That Are Correlated to Developing Multiple Endocrine Neoplasia (MEN) and Pancreatic Neuroendocrine Tumors (PNET)

Hyperparathyroidism | Multiple Endocrine Neoplasia | Pancreatic Neuroendocrine Tumors

United States

Clinical Trials on Pancreatic Beta Cell Adenoma

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