Clinical Trials on Paramyxoviridae Infections in South Africa

Total 3285 results

Bavarian Nordic

Completed

Study to Evaluate Safety, Dose Response and Immunogenicity of the Measles Vaccine MVA mBN85B in Healthy Children Aged 6 Months to 6 Years

Measles

South Africa
University of Witwatersrand, South Africa

Unknown

Safety and Immunogenicity of Measles Vaccine, Varicella Vaccine and Hepatitis-A Vaccine (MV/VV/Hep-AV)

Measles | Hepatitis A | Varicella

South Africa
Ark Biosciences Inc.

Terminated

A Study of AK0529 in Infants Hospitalized With RSV

Respiratory Syncytial Virus Infections

Australia
AstraZeneca
Iqvia Pty Ltd

Completed

Evaluate the Safety and Tolerability, for Nirsevimab in Immunocompromised Children (MUSIC)

RSV Infection

United States, Belgium, Spain, Japan, Poland, South Africa, United Kingdom, Ukraine
GlaxoSmithKline

Completed

A Study on the Immune Response and Safety Elicited by a Vaccine Against Respiratory Syncytial Virus (RSV) When Given Alone and Together With a Vaccine Against Influenza in Adults Aged 60 Years and Above

Respiratory Syncytial Virus Infections

Panama, New Zealand, South Africa
Beth Israel Deaconess Medical Center
University of Stellenbosch

Recruiting

Testing Health Workers At Risk to Advance Our Understanding of TB Infection (THWART-TB)

Tuberculosis | Tuberculosis Infection

South Africa
GlaxoSmithKline
Parexel

Completed

Bioequivalence Study Between GR37547 500 Milligrams (mg) Tablet Versus Ciprofloxacin 500 mg Tablet Reference Product in Healthy Adult Subjects

Infections, Bacterial

South Africa
Case Western Reserve University
Thrasher Research Fund

Completed

Diagnosis of Tuberculosis Infection in HIV Co-infected Children (ThrasherIGRA)

HIV Infections | Tuberculosis | Latent Tuberculosis Infection

South Africa
International AIDS Vaccine Initiative
Biofabri, S.L; South African Tuberculosis Vaccine Initiative; Universidad de...

Completed

MTBVAC Study in Adults With and Without Latent Tuberculosis Infection in South Africa (A-050)

Tuberculosis

South Africa
National Institute of Allergy and Infectious Diseases...

Completed

Micronutrients and Enteric Infections in African Children

Enteric Infections

South Africa
Shabir Madhi

Recruiting

Surveillance Among Healthcare Workers for SARS-Coronavirus-2 Infection

COVID-19 | SARS-CoV2 Infection

South Africa
Aeras
Statens Serum Institut

Completed

Safety and Immunogenicity Study of AERAS-456 Vaccine for Tuberculosis

Latent Tuberculosis | Latent Tuberculosis Bacteriology and Histology Unknown

South Africa
Centers for Disease Control and Prevention
Johns Hopkins University; Sanofi; University of Stellenbosch; University of Cape... and other collaborators

Recruiting

Tuberculosis Clinical Trials Consortium Study 35

Latent Tuberculosis

South Africa
University of Bern
University of Alabama at Birmingham; University of Southern California; Louisiana... and other collaborators

Active, not recruiting

Genital Tract Infections, the Vaginal Microbiome and Gestational Age at Birth Among Pregnant Women in South Africa

HIV Infections | Premature Birth | Microbial Colonization | Pregnancy; Infection | Bacterial Vaginosis | Trichomonas Vaginitis | Neisseria Gonorrheae Infection | Chlamydia Trachomatis Infection | Mycoplasma Genitalium Infection | Genital Mycoplasma Infection | Vaginal Candida | Sexually Transmitted Infections... and other conditions

South Africa
Archivel Farma S.L.
Parexel

Completed

Clinical Trial to Investigate the Safety, Tolerability, and Immunogenicity of the Novel Antituberculous Vaccine RUTI® Following One Month of Isoniazid Treatment in Subjects With Latent Tuberculosis Infection

Tuberculosis | Latent Tuberculosis Infection

South Africa
Professor Francois Venter
University of Cape Town

Completed

The Effect of Rifampicin on the Pharmacokinetics of Intracellular Tenofovir-diphosphate and Tenofovir When Coadministered With Tenofovir Alafenamide Fumarate During the Maintenance Phase of Tuberculosis Treatment in TB/HIV-1 Coinfected Participants (EpiTAF)

Tuberculosis | HIV-1-infection

South Africa
Minervax ApS
European and Developing Countries Clinical Trials Partnership (EDCTP)

Completed

Study of a Group B Streptococcus Vaccine in Pregnant Women Living With HIV and in Pregnant Women Who do Not Have HIV

Group B Streptococcal Infection

South Africa, Uganda
University of Cape Town
London School of Hygiene and Tropical Medicine; Johns Hopkins University; Imperial... and other collaborators

Completed

Isoniazid Plus Antiretroviral Therapy to Prevent Tuberculosis in HIV-infected Persons (HAART-IPT)

HIV Infections | Tuberculosis | Latent Tuberculosis Infection

South Africa
Gilead Sciences

Completed

Rollover Study Protocol for Pediatric Patients in South Africa for Continued Access to Emtricitabine

HIV-1 Infection

South Africa
Foundation for Innovative New Diagnostics, Switzerland

Completed

Novel Rapid POC Diagnostics for COVID-19

COVID-19 Respiratory Infection

Georgia, South Africa
ApoPharma

Completed

Antiretroviral Activity and Pharmacokinetics of Deferiprone in Healthy Volunteers and Asymptomatic HIV-infected Subjects

HIV Infection

South Africa
GlaxoSmithKline

Completed

Bioequivalence Study Between SKF101804 Cefixime 200 Milligram (mg)/5 Milliliter (mL) Suspension Versus Cefixime 200 mg/5 mL Suspension Reference Product in Healthy Adult Subjects Under Fasting Conditions

Infections, Bacterial

South Africa
French National Agency for Research on AIDS and...

Completed

Pharmacokinetics of Rifabutin Combined With Antiretroviral Therapy in Patients With TB/HIV Co-infection in South Africa

HIV Infections | Tuberculosis

South Africa
University of Pretoria

Not yet recruiting

Kefazolin Versus Kefazolin Plus Metronidazole to Reduce Postpartum Infection

Prevention of Postpartum Sepsis

South Africa
Desmond Tutu HIV Centre
Merck Sharp & Dohme LLC; European and Developing Countries Clinical Trials...

Unknown

Preparing for Adolescent HIV Vaccine Trials in South Africa: (CATSA)

HIV Infections | HIV Infection

South Africa
National Institute for Communicable Diseases, South...
Bill and Melinda Gates Foundation; Centers for Disease Control and Prevention

Unknown

Effectiveness of Trivalent Inactivated Influenza Maternal Vaccination Among Pregnant Women and Their Newborns in South Africa

Influenza Viral Infections

South Africa
Centre for the AIDS Programme of Research in South...

Completed

A Study to Compare Three Existing Starting Points of Anti-Retroviral Therapy (ART) Initiation in HIV/Tuberculosis (TB) Co-infected Patients (SAPIT)

HIV Infections | Tuberculosis

South Africa
Centers for Disease Control and Prevention
United States Agency for International Development (USAID); Bill and Melinda... and other collaborators

Unknown

Prevention of Perinatal Sepsis (PoPS): Evaluation of Chlorhexidine Wipes of Birth Canal and Newborn

Sepsis | Infant, Newborn, Diseases | Puerperal Infection

South Africa
Sanofi Pasteur, a Sanofi Company

Recruiting

Study of a Respiratory Syncytial Virus Candidate Formulation in Adults Aged 60 Years and Older

Healthy Volunteers | Respiratory Syncytial Virus Infection

Australia
University of North Carolina, Chapel Hill
University of Pretoria; SADC Research Centre

Completed

Impact Evaluation of a School-Based Sexuality and HIV Prevention Education Activity in South Africa

HIV Infections | Pregnancy Related | HSV-2 Infection

South Africa
Professor Francois Venter

Recruiting

ADORE: Efficacy of DORavirine in Adults Living With HIV Experiencing Virological Failure on First-line Efavirenz-based Antiretroviral Therapy With NNRTI Resistance (ADORE)

HIV-1-infection

South Africa
Professor Francois Venter

Completed

ADVANCE Study of DTG + TAF + FTC vs DTG + TDF + FTC and EFV + TDF+FTC in First-line Antiretroviral Therapy (ADVANCE)

HIV-1 Infection

South Africa
University of Witwatersrand, South Africa
SynaVir

Completed

Study of Oral Administration of Ribavirin and Nitazoxamide Versus Placebo in COVID-19 (DuACT)

Covid19 | SARS-CoV Infection

South Africa
University of Cape Town
University of Zurich

Recruiting

Gene Expression Profiles in Spinal Tuberculosis. (SpinalTBX)

Infections | Musculoskeletal Diseases | Mycobacterium Infections | Tuberculosis | Spondylitis | Bone Diseases, Infectious | Diagnostic Imaging | Positron-Emission Tomography | Spondylodiscitis | Spinal Disease | Tuberculosis, Spinal | Tuberculosis, Osteoarticular | Diagnostic Techniques and Procedures | Spondylitis...

South Africa
Johns Hopkins University
Aurum Institute; UNITAID; KNCV Tuberculosis Foundation

Completed

Qualitative Understanding of Community TB Services Pre and Post the CHIP-TB Trial

Tuberculosis Infection | Tuberculosis Prevention

Ethiopia, South Africa
Queen Mary University of London
University of Cape Town

Completed

Trial of Vitamin D Supplementation in Cape Town Primary Schoolchildren (ViDiKids)

Latent Tuberculosis

South Africa
Sanofi Pasteur, a Sanofi Company

Completed

DTaP-IPV-HB-PRP-T Combined Vaccine as a Primary Series and a Second Year of Life Booster in HIV-Exposed Infected and Uninfected Infants

Hepatitis B | Pertussis | Tetanus | Diphtheria | Polio | Human Immunodeficiency Virus Infection

South Africa
Novartis Vaccines

Completed

Magnitude of the Antibody Response to and Safety of a GBS Trivalent Vaccine in HIV Positive and HIV Negative Pregnant Women and Their Offsprings

Bacterial Infections | Streptococcal Infections | Gram-Positive Bacterial Infections

South Africa, Malawi
The Aurum Institute NPC
Johns Hopkins University; University of California

Completed

Safety Tolerability DDI Short Course Treatment of LTBI Infection With High-dose Rifapentine and Isoniazid or Standard Isoniazid Preventive Therapy in HIV+ Patients (DOLPHIN & DOLPHIN TOO) (IMPAACT4TB)

HIV Infections | Respiratory Tract Infections

South Africa
Drexel University
University of North Carolina, Chapel Hill; University of KwaZulu

Completed

MAMAS: Mentoring Adolescent Mothers at School (MAMAS)

Chlamydia | Gonorrhea | Human Immunodeficiency Virus | Trichomonas Vaginitis | Herpes Simplex Type II

South Africa
Vanderbilt University Medical Center
National Institute of Mental Health (NIMH)

Completed

Traditional Healer-initiated HIV Counseling and Testing in South Africa

HIV Infection

South Africa
University of Miami
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Promoting Male Involvement to Improve Prevention of Mother to Child Transmission (PMTCT) Uptake and Reduce Antenatal Infection

Pregnancy | HIV

South Africa
University of Stellenbosch

Recruiting

Host Blood RNA Signatures for Diagnosis of TB (RADIANT)

Tuberculosis | Lower Respiratory Infection

South Africa
University of Witwatersrand, South Africa

Completed

COVID-19 Prophylaxis South Africa (COVER HCW) (COVER)

Covid19 | SARS-CoV Infection

South Africa
Centers for Disease Control and Prevention
London School of Hygiene and Tropical Medicine; National Institute for Communicable...

Completed

Episodic Acyclovir Therapy for Genital Ulcers

HIV Infections | Ulcer | Herpes Simplex

South Africa
Shanghai Ark Biopharmaceutical Co., Ltd.
Ark Biosciences Pty Ltd.

Completed

Viral Inhibition in Children for Treatment of RSV (VICTOR)

RESPIRATORY SYNCYTIAL VIRUS INFECTIONS

Australia, Hong Kong, Israel, Lebanon, Malaysia, Poland, Taiwan, Turkey
Enanta Pharmaceuticals, Inc

Terminated

Effects of EDP-938 in Hematopoietic Cell Transplant Recipients Who Are Infected With Acute Respiratory Syncytial Virus (RSV) of the Upper Respiratory Tract (RSVTx)

Respiratory Syncytial Virus Infections

Spain, Korea, Republic of, Israel, Canada, United States, Italy, France, Belgium, Brazil, Taiwan, Greece, Argentina, Mexico, South Africa, China, Poland, Colombia, Turkey, United Kingdom
Sanofi Pasteur, a Sanofi Company

Recruiting

Study of the Safety and Immune Response of an Investigational mRNA Vaccine for the Prevention of Respiratory Syncytial Virus and/or Human Metapneumovirus in Participants Aged 18 to 49 Years and 60 Years and Older

Healthy Volunteers | Respiratory Syncytial Virus Infection | Metapneumovirus Infection

Australia, United States
Gilead Sciences

Active, not recruiting

Study of VRC07-523LS, CAP256V2LS, and Vesatolimod, in Early Antiretroviral-treated HIV-1 Clade C-infected Women

HIV-1-infection

South Africa
Johns Hopkins University
National Institute of Allergy and Infectious Diseases (NIAID); University of...

Completed

Quantiferon Gold Test for Detecting Tuberculosis (TB) Infection in HIV/AIDS Patients in South Africa

HIV | Latent Tuberculosis

South Africa

Clinical Trials on Paramyxoviridae Infections in South Africa

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