Clinical Trials on Parkinson's Disease With Dementia

Total 14010 results

Thammasat University

Completed

One-Leg Standing Radiograph: A Novel Technique to Evaluate the Severity of OA Knee (OA knee)

Severity of OA Knee | Difference of Joint Space Width Between One-leg and Both-leg Standing Radiograph

Thailand
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Doxorubicin and Gemcitabine in Treating Patients With Locally Recurrent or Metastatic Unresectable Renal Cell Carcinoma

Metastatic Renal Cell Carcinoma | Renal Cell Carcinoma With Sarcomatoid Features

United States
The Leeds Teaching Hospitals NHS Trust
University of Leeds

Not yet recruiting

Amyloid Proteins From Medullary Thyroid Cancer and Laryngeal Amyloidosis

Dementia | Alzheimer Disease | Amyloid | Medullary Thyroid Cancer
Ignis Therapeutics (Suzhou) Limited

Recruiting

A Twelve-week, Double-blind, Placebo-controlled, Randomized, Parallel-group, Multicenter Study to Evaluate the Efficacy and Safety of Solriamfetol in the Treatment of Excessive Daytime Sleepiness (EDS) in Patients With Obstructive Sleep Apnea (OSA)

Excessive Daytime Sleepiness Associated With Obstructive Sleep Apnea

China
Novartis Pharmaceuticals

Terminated

Study of Nilotinib in Ph+ CML-CP Patients With Low Imatinib Trough Plasma Concentrations (MACS1148)

CML | Philadelphia Chromosome Positive (Ph+) | Chronic Myelogenous Leukemia Chronic Phase(CML-CP) Patients With Low Imatinib Trough Levels

United States
U.S. Army Medical Research and Development Command

Completed

mTBI Mechanisms of Action of HBO2 for Persistent Post-Concussive Symptoms (BIMA)

Post-Concussion Syndrome | Traumatic Brain Injury With Brief Loss of Consciousness

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...
Pregnolia AG

Recruiting

Cervical Softening and the Prediction of Preterm Birth (STIPP)

Premature Birth | Preterm Birth | Diagnosis | Threatened Preterm Labor | Cervical Incompetence in Pregnancy as Antepartum Condition | Premature Labor | Cervical Incompetence, With Delivery

Netherlands
Targeted Therapy Technologies, LLC

Unknown

Episcleral Dexamethasone for Treatment of Macular Edema and Inflammatory Disorders of the Posterior Pole

Macular Edema | Epiretinal Membrane | Branch Retinal Vein Occlusion | Radiation Retinopathy | Central Serous Retinopathy With Pit of Optic Disc | Commotio Retinae | Vitritis

United States
University of California, Irvine
VA Long Beach Healthcare System

Not yet recruiting

Plant-Focused Nutrition in Patients With Diabetes and Chronic Kidney Disease (PLAFOND)

Diabetes Mellitus | Diabetic Kidney Disease | CKD Stage 4 | CKD Stage 5 | CKD Stage 3 | Chronic Kidney Disease (CKD) With Diabetes Mellitus (DM)
University of Colorado, Denver
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Recruiting

COMT Inhibition Among Individuals With Comorbid AUD/ADHD

Attention Deficit Hyperactivity Disorder | Alcohol Use Disorder

United States
National Cancer Institute (NCI)

Completed

Ipilimumab After Allogeneic Stem Cell Transplant in Treating Patients With Persistent or Progressive Cancer

Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Recurrent Adult Acute Myeloid Leukemia | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Immunoblastic Large Cell Lymphoma and other conditions

United States
All India Institute of Medical Sciences, Bhubaneswar

Recruiting

Comorbidities Resolution After MGB Surgery and Change in Body Composition (MOGAMBO)

Hypertension | Hypothyroidism | Sleep Apnea | Morbid Obesity | Lipid Disorder | Non-Alcoholic Fatty Liver Disease | Type2diabetes | Chronic Venous Hypertension With Ulcer

India
Parc Sanitari Pere Virgili
Althaia Xarxa Assistencial Universitària de Manresa; Hospital Vall d'Hebron; Consorci... and other collaborators

Completed

Diabetes as an Accelerator of Cognitive Impairment and Alzheimer's Disease (DIALCAT)

Patients Aged 65-85 (Both Included) | Diagnosed of Mild Cognitive Impairment | Diagnosed of Type 2 Diabetes in Active Treatment (Hypoglycemic Agents) for a Period ≥5 Years

Spain
King Abdulaziz University

Recruiting

The Efficacy of Continuous Positive Airway Pressure in Achieving Asthma Control in Patients With Severe Asthma and Obstructive Sleep Apnea

Severe Asthma With Obstructive Sleep Apnea

Saudi Arabia
Targeted Therapy Technologies, LLC

Recruiting

Phase I Study of Episcleral Celecoxib for Treatment of Macular Edema and Inflammatory Disorders of the Posterior Pole

Macula Edema | Epiretinal Membrane | Branch Retinal Vein Occlusion | Radiation Retinopathy | Central Serous Retinopathy With Pit of Optic Disc | Commotio Retinae | Vitritis

United States
Centre for Addiction and Mental Health

Recruiting

Matching Assessment and Treatment for Children With Disruptive Behaviour and Their Parents (MATCH-DB)

Emotional Disorder | Attention Deficit Hyperactivity Disorder | Conduct Disorder | Oppositional Defiant Disorder | Disruptive Behavior Disorder | Behavioural Disorder

Canada
National Cancer Institute (NCI)

Completed

Tretinoin, Cytarabine, and Daunorubicin Hydrochloride With or Without Arsenic Trioxide Followed by Tretinoin With or Without Mercaptopurine and Methotrexate in Treating Patients With Acute Promyelocytic Leukemia

Untreated Adult Acute Myeloid Leukemia | Adult Acute Promyelocytic Leukemia (M3) | Childhood Acute Promyelocytic Leukemia (M3) | Adult Acute Myeloid Leukemia With t(15;17)(q22;q12) | Untreated Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies

United States
Weill Medical College of Cornell University
Oncolys BioPharma Inc

Terminated

Phase 2 Study of OBP-301 (Telomelysin™) in Combination With Pembrolizumab and SBRT in Patients With HNSCC With Inoperable, Recurrent or Progressive Disease

Head and Neck Squamous Cell Carcinoma With Inoperable Recurrent or Progressive Disease

United States
Pirogov Russian National Research Medical University

Completed

Endometrial Tissues and Mononuclear Cells Receptivity in Pathogenesis of Endometrial Proliferative Processes

Endometrial Cancer | Endometrial Hyperplasia Without Atypia | Postmenopause | Peripheral Blood Mononuclear Cells | Endometrial Hyperplasia With Atypia | Estrogen Receptor | Progesterone Receptor
Joanne Kurtzberg, MD
The Marcus Foundation

Recruiting

UCB Transplant of Inherited Metabolic Diseases With Administration of Intrathecal UCB Derived Oligodendrocyte-Like Cells (DUOC-01)

Mucopolysaccharidosis II | Brain Diseases, Metabolic, Inborn | Adrenoleukodystrophy | Batten Disease | Leukodystrophy, Metachromatic | Leukodystrophy, Globoid Cell | Alpha-Mannosidosis | Tay-Sachs Disease | Pelizaeus-Merzbacher Disease | Sandhoff Disease | Neimann Pick Disease | Sanfilippo Mucopolysaccharidoses

United States
Fundació Institut de Recerca de l'Hospital de la...

Unknown

Sleep in Adults With Down Syndrome and Alzheimer's Disease

Obstructive Sleep Apnea | Alzheimer's Disease | Sleep Disturbances

Spain
Lawson Health Research Institute
The Ottawa Hospital; Hamilton Health Sciences Corporation; Dalhousie University; Niagara Health System

Active, not recruiting

Rivaroxaban or Aspirin As Thromboprophylaxis in Multiple Myeloma (RithMM)

Multiple Myeloma in Relapse | Multiple Myeloma With Failed Remission | Multiple Myeloma Stage I | Multiple Myeloma Progression | Multiple Myeloma Stage II | Multiple Myeloma Stage III

Canada
Bulgarian Cardiac Institute

Completed

Acute Coronary Syndrome in Patients With COVID-19 (ACS-COVID)

to Find a Clinical or Laboratory Parameter, That Would Help in Distinguishing Between COVID-19 Patients With MI and IRA and Those, Who Have no IRA

Bulgaria
University of Colorado, Denver
National Institute on Aging (NIA)

Completed

Advancing Understanding of Transportation Options (AUTO)

Stroke | Multiple Sclerosis | Glaucoma | Brain Injuries | Macular Degeneration | Arthritis | Chronic Obstructive Pulmonary Disease | Parkinson Disease | Restless Legs Syndrome | Diabetic Retinopathy | Insomnia | Retinitis Pigmentosa | Obstructive Sleep Apnea | Dementia | End Stage Renal Disease | Sleep Apnea | Syncope | Seizures and other conditions

United States
Chinese University of Hong Kong

Not yet recruiting

SWELE Program: An Unstructured Outdoor Play With Mindfulness-based Interventions to Promote Mental Health Among Students With Special Education Needs (SEN)

Autism Spectrum Disorder | Attention Deficit Hyperactivity Disorder | Physical Disability | Specific Learning Disorder | Intellectual Disability, Mild to Moderate
HealthRhythms, Inc.
National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Institutes...

Completed

Smartphone-Based Intervention for Sleep Disturbance in Individuals Recovering From Alcohol Use Disorder

Sleep Disorder | Sleep Disturbance | Alcohol Use Disorder (AUD) | Alcohol Abuse With Alcohol-Induced Sleep Disorder

United States
Massachusetts General Hospital
Louis V. Gerstner III Research Scholar Award

Completed

Computerized Working Memory Training in Children With ADHD and Comorbid Tourette Syndrome

Tourette Syndrome | Attention-Deficit/Hyperactivity Disorder
Corporal Michael J. Crescenz VA Medical Center

Unknown

Smoking Cessation With Varenicline in Schizophrenia: Antipsychotic-Induced Neurological Symptoms as Correlates

Schizophrenia | Schizoaffective Disorder | Tobacco Smoking | Tardive Dyskinesia | Parkinsonism

United States
AstraZeneca
ISTITUTO REGINA ELENA - CENTRO RICERCHE SPERIMENTALI

Terminated

ZD4054 (Zibotentan) or Placebo Plus Chemotherapy in Patients With Advanced Ovarian Cancer

Patients With Advanced Ovarian Cancer Sensitive to Platinum-based Chemotherapy

Italy, Germany
Apurano Pharmaceuticals GmbH

Recruiting

Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Diabetic Polyneuropathy

Pain | Diabetes | Diabetic Neuropathies | Chronic Pain | Peripheral Neuropathy | Pain, Chronic | Chronic Pain Syndrome | Diabetic Polyneuropathy | Pain Syndrome | Peripheral Neuralgia | Peripheral Neuropathy With Type 2 Diabetis

Germany
Huashan Hospital
The First Affiliated Hospital with Nanjing Medical University; The First Affiliated... and other collaborators

Recruiting

Real World Study of Classic Infectious Disease

Brucelloses | Epidemic Hemorrhagic Fever | Kala-Azar

China
Beth Israel Deaconess Medical Center

Not yet recruiting

CEReBral AutorEgulation in Non-cardiac SuRgery and Relationship to Postoperative DeliriUm State (CERBERUS)

Postoperative Delirium | Postoperative Cognitive Dysfunction | Cerebral Hypoperfusion | Perioperative/Postoperative Complications | Intraoperative Hypotension | EEG With Periodic Abnormalities
IRCCS Policlinico S. Donato
University of Pavia

Recruiting

New Patient-specific Functional Assessment of the Anomalous Aortic Origin of Coronary Arteries. (NECESSARY)

Myocardial Ischemia | Sudden Cardiac Death | Anomalous Coronary Artery Origin | Anomalous Coronary Artery Arising From the Opposite Sinus | Anomalous Coronary Artery Course | Anomalous Coronary Artery With Aortic Origin and Course Between the Great Arteries

Italy
Baxalta now part of Shire

Terminated

Phase 1/2a Two-Arm Dose-Escalation Study of BAX69 in Subjects With Malignant Ascites of Ovarian Cancer

Refractory Ovarian Cancer With Recurrent Symptomatic Malignant Ascites

United States
Apurano Pharmaceuticals GmbH

Recruiting

Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Diabetic Polyneuropathy

Pain | Diabetes | Diabetic Neuropathies | Chronic Pain | Peripheral Neuropathy | Pain, Chronic | Chronic Pain Syndrome | Diabetic Polyneuropathy | Pain Syndrome | Peripheral Neuralgia | Peripheral Neuropathy With Type 2 Diabetis

Germany
michal roll

Recruiting

Safety and Efficacy Study Using 5-ALA Oral Administration as an Adjuvant Therapy on the Rate of Local Tumor Recurrence in Patients Who Have Desmoids Tumors

Surgical Resection | The Aim of the Study is to Evaluate the Efficacy of Photodynamic Therapy as an | Adjuvant Therapy on the Clinical Outcome of Patients With Desmoid Tumors After

Israel
University of Michigan
Northwestern University; Food and Drug Administration (FDA)

Recruiting

Interview Study of Adult and Child Patients and Parents of Children With Swelling Due to Nephrotic Syndrome. (Prepare-NS)

Edema | Fluid Overload | Glomerulosclerosis, Focal Segmental | Nephrotic Syndrome | Glomerular Disease | Minimal Change Disease | Membranous Nephropathy | Nephrotic Syndrome in Children | Nephrotic Syndrome, Minimal Change | FSGS | Minimal Change Nephrotic Syndrome | IgM Nephropathy | Nephrotic Syndrome With Edema...

United States
Chinese University of Hong Kong
Health and Medical Research Fund

Recruiting

New Cross-linked Hyaluronan Gel to Prevent Adhesion After USG-MVA: RCT

First Trimester Abortion | Surgical Abortion | Miscarriage With Afibrinogenemia

Hong Kong
Chinese PLA General Hospital

Unknown

Clinical Study in Treatment of Malignant Ascites of Ovarian Cancer With Intraperitoneal Injection Bevacizumab Combined With Intraperitoneal Hyperthermic Perfusion Chemotherapy

Ovarian Cancer With Malignant Ascites

China
MedtronicNeuro

Completed

Restore Claims Characterization Study

Chronic Refractory Pain Associated With Failed Back Surgery Syndrome, Epidural Fibrosis, Peripheral Causalgia, Complex Regional Pain Syndrome

United States
University Medical Center Groningen
Juvenile Diabetes Research Foundation; Lexicon Pharmaceuticals

Not yet recruiting

Ambrisentan Sotagliflozin and Prevention of Renal Injury; a Randomized Evaluation (ASPIRE)

Type 1 Diabetes Mellitus With Diabetic Nephropathy

Netherlands, United States, Canada, Denmark, Finland
Bedford Hospital NHS Trust
Moorfields Eye Hospital NHS Foundation Trust; University Hospitals Bristol... and other collaborators

Unknown

Treating Dry Eyes and Corneal Ulcers With Fingerprick Autologous Blood (FAB)

Dry Eyes | Sjogren's Disease With Dry Eyes | Persistent Corneal Epithelial Defects | Chronic Corneal Ulcers

United Kingdom
National Cancer Institute (NCI)

Completed

Cediranib Maleate in Treating Patients With Recurrent or Newly Diagnosed Metastatic Head and Neck Cancer

Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Salivary Gland Squamous Cell Carcinoma | Recurrent Lip and Oral Cavity Squamous Cell Carcinoma | Recurrent Nasopharyngeal Keratinizing Squamous... and other conditions

United States
National Institute of Mental Health (NIMH)

Completed

A Controlled Trial of Serotonin Reuptake Inhibitors Added to Stimulant Medication in Youth With Severe Mood Dysregulation

Attention Deficit Hyperactivity Disorder | Mood Disorder | Attention Deficit and Disruptive Behavior Disorder | Mental Disorder Diagnosed in Childhood

United States
Pacific Coast Family Medical Group

Enrolling by invitation

Disease Prevention in Clinical Practice Base on Patient Specific Physiology (STOPDISEASE)

Cancer | Atherosclerosis | Atrial Fibrillation | Insulin Resistance | Dementia | PreDiabetes | Type2 Diabetes | NASH - Nonalcoholic Steatohepatitis | Diastolic Dysfunction | Carotid Plaque
Assiut University

Not yet recruiting

Acute Kidney Injury After Cardiac Surgery

Heart Diseases | Heart Valve Diseases | Acute Kidney Injury | Cardiopulmonary Arrest With Successful Resuscitation | Cardio-Renal Syndrome | Cardiac Disease | Coronary Artery Bypass Surgery | Cardiothoracic Surgery | Cardio-pulmonary Bypass | Cardiopulmonary Disease | Cardio Respiratory Arrest | Heart Shock | Acute...
PharmaMar

Completed

Study Escalating Doses of PM01183 in Combination With Fixed Doxorubicin in Patients With Specific Advanced Unresectable Solid Tumors

Neuroendocrine Tumors | Endometrial Adenocarcinomas | Small-cell Lung Cancer With Less Than 2 Prior Cytotoxic-containing Lines of Therapy

Spain, United Kingdom
National Taiwan University Hospital

Completed

BOO and DU and Their Clinical and Urodynamic Findings in Women With ≥Stage II Cystocele

Bladder Outlet Obstruction and Detrusor Underactivity in Women With Severe Cystocele
Haukeland University Hospital
Ullevaal University Hospital; Stiftelsen Helse og Rehabilitering

Completed

Multidisciplinary Treatment in Patients With Mild Traumatic Brain Injury

Traumatic Brain Injury With Brief Loss of Consciousness

Norway
National Cancer Institute (NCI)

Completed

Vinorelbine Tartrate and Cyclophosphamide in Combination With Bevacizumab or Temsirolimus in Treating Patients With Recurrent or Refractory Rhabdomyosarcoma

Recurrent Childhood Rhabdomyosarcoma | Recurrent Adult Soft Tissue Sarcoma | Previously Treated Childhood Rhabdomyosarcoma | Adult Rhabdomyosarcoma | Childhood Alveolar Rhabdomyosarcoma | Childhood Pleomorphic Rhabdomyosarcoma | Childhood Rhabdomyosarcoma With Mixed Embryonal and Alveolar Features

United States, Canada, Australia, New Zealand

Clinical Trials on Parkinson's Disease With Dementia

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