Clinical Trials on Patient Admitted to Intensive Care Unit for COVID-19

Total 551 results

Windtree Therapeutics

Completed

The Safety and Preliminary Tolerability of Lyophilized Lucinactant in Adults With Coronavirus Disease 2019 (COVID-19)

COVID-19 | Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)

United States, Argentina
University of Lausanne Hospitals

Completed

Physiological Response to Prone Position in COVID-19 Associated Acute Respiratory Distress Syndrome (ARDS)

ARDS | Sars-CoV-2 Infection

Switzerland
Joshua M Hare

Withdrawn

Umbilical Cord Tissue (UC) Derived Mesenchymal Stem Cells (MSCs) Versus Placebo to Treat Acute Pulmonary Inflammation Due to COVID-19 (COVID-19)

COVID-19 | Acute Respiratory Distress Syndrome | Corona Virus Infection
University of Alabama at Birmingham

Completed

Prolonged Prone Positioning for COVID-19-induced Acute Respiratory Distress Syndrome (ARDS)

Covid19 | ARDS | Acute Hypoxemic Respiratory Failure

United States
Reven Pharmaceuticals, Inc.

Active, not recruiting

Tolerability and Efficacy of RJX in Patients With COVID-19 (RJX)

COVID-19 | Acute Respiratory Distress Syndrome | SARS-CoV-2 | Hypoxemia

United States
Camillo Ricordi

Completed

Use of UC-MSCs for COVID-19 Patients

COVID-19 | Acute Respiratory Distress Syndrome | Corona Virus Infection | ARDS | ARDS, Human

United States
Bicetre Hospital

Completed

Hemodynamic Characteristics of Patients With SARS-CoV-2 (PiCCOVID)

COVID-19 | Shock | Acute Respiratory Distress Syndrome | SARS-CoV-2 | Fluid Overload | Coronavirus | Left Ventricular Dysfunction | Acute Circulatory Failure

France
University Hospital, Clermont-Ferrand
Groupe Hospitalier Pitie-Salpetriere; University Hospital Schleswig-Holstein; Hospital Clínico Universitario de Valencia

Completed

Inhaled Sedation in COVID-19-related Acute Respiratory Distress Syndrome (ISCA): an International Research Data Study in the Recent Context of Widespread Disease Resulting From the 2019 (SARS-CoV2) Coronavirus Pandemics (COVID-19) (ISCA)

Acute Respiratory Distress Syndrome | Sedation | Invasive Mechanical Ventilation | Critically Illness

United States, France, Spain, Germany, Switzerland
Helsinki University Central Hospital

Completed

Outcome of COVID-19 Patients After Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome

COVID-19 | Acute Respiratory Distress Syndrome | Extracorporeal Membrane Oxygenation Complication

Sweden, Finland, Germany, Italy, United Kingdom, France
Hope Pharmaceuticals

Withdrawn

Treatment of Lung Injury From COVID-19 Infection With Intravenous Sodium Nitrite

COVID-19 | Acute Respiratory Distress Syndrome | Acute Respiratory Failure

United States
Beijing Tiantan Hospital

Not yet recruiting

Sivelestat for Acute Respiratory Distress Syndrome Due to COVID-19

Respiratory Failure | Respiratory Infection Virus
Olive View-UCLA Education & Research Institute

Recruiting

Point-of-care Lung Ultrasound (POCUS)-Integrated Study of Admitted Patients With COVID-19 (PIOS-COVID)

Covid19 | Lung Injury | Acute Respiratory Distress Syndrome | ARDS | Acute Cardiac Event | Hypoxemia | Ultrasound

United States
University Hospital, Strasbourg, France

Terminated

Impact of Intravenous Lidocaine on Clinical Outcomes of Patients With ARDS During COVID-19 Pandemia (LidoCovid)

COVID-19 | Corona Virus Infection | Acute Respiratory Distress Syndrome (ARDS)

France
EyePoint Pharmaceuticals, Inc.
Medical Technology Enterprise Consortium (MTEC)

Terminated

Evaluation of the Safety and Efficacy of Razuprotafib in Hospitalized Subjects With Coronavirus Disease 2019 (RESCUE)

COVID-19 | Acute Respiratory Distress Syndrome (ARDS)

United States
Dr. Jurjan Aman
Exvastat Ltd.; Simbec-Orion Group; KABS laboratories

Terminated

Intravenous Imatinib in Mechanically Ventilated COVID-19 Patients (INVENT COVID)

Covid19 | Endothelial Dysfunction | Acute Respiratory Distress Syndrome | ARDS | Pulmonary Edema

Netherlands
University of Minnesota

Completed

Losartan for Patients With COVID-19 Not Requiring Hospitalization

Acute Respiratory Distress Syndrome | Corona Virus Infection | SARS-CoV Infection

United States
Acticor Biotech

Completed

Glenzocimab in SARS-Cov-2 Acute Respiratory DistrEss syNdrome Related to COVID-19 (GARDEN)

COVID-19 | Acute Respiratory Distress Syndrome | ARDS | SARS-CoV Infection

France
Centre Chirurgical Marie Lannelongue

Terminated

Dexamethasone Treatment for Severe Acute Respiratory Distress Syndrome Induced by COVID-19 (DHYSCO)

COVID-19 | Respiratory Distress Syndrome, Adult

France
Alexion Pharmaceuticals

No longer available

SOLIRIS® (Eculizumab) Treatment of Participants With COVID-19

COVID-19 | Pneumonia, Viral | Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)

United States, France
Maimónides Biomedical Research Institute of Córdoba

Completed

Pilot Study of Antithrombin as Prophylaxis of Acute Respiratory Distress Syndrome in Patients With COVID-19

Severe Acute Respiratory Syndrome | Covid19 | Distress Respiratory Syndrome

Spain
Hospital General Universitario Gregorio Marañon
Instituto de Salud Carlos III

Recruiting

Cell Therapy With Treg Cells Obtained From Thymic Tissue (thyTreg) to Control the Immune Hyperactivation Associated With COVID-19 and/or Acute Respiratory Distress Syndrome (THYTECH2) (THYTECH2)

Systemic Inflammatory Response Syndrome

Spain
AVEM HealthCare

Not yet recruiting

The Use of Exosomes for the Treatment of Acute Respiratory Distress Syndrome or Novel Coronavirus Pneumonia Caused by COVID-19 (ARDOXSO)

Covid19 | Acute Respiratory Distress Syndrome | Novel Coronavirus Pneumonia

United States
Ministry of Health, Brazil
InCor Heart Institute

Recruiting

Prevention of Acute Myocardial Injury by Trimetazidine in Patients Hospitalized for COVID-19 (PREMIER)

Myocardial Injury | Covid19 | Acute Respiratory Distress Syndrome

Brazil
Aveni Foundation

Withdrawn

CORONA: A Study Using DeltaRex-G Gene Therapy for Symptomatic COVID-19 (CORONA)

COVID-19 | Acute Respiratory Distress Syndrome | Cytokine Storm
The University of Texas Health Science Center,...
United States Department of Defense; Akebia Therapeutics Inc.

Completed

Vadadustat for the Prevention and Treatment of Acute Respiratory Distress Syndrome (ARDS) in Hospitalized Patients With Coronavirus Disease 2019 (COVID-19)

Coronavirus Infection | Acute Respiratory Distress Syndrome

United States
Banc de Sang i Teixits

Completed

Efficacy and Safety Evaluation of Mesenchymal Stem Cells for the Treatment of Patients With Respiratory Distress Due to COVID-19 (COVIDMES)

COVID-19 | SARS-CoV 2 | Adult Respiratory Distress Syndrome

Spain
University of Minnesota
Bill and Melinda Gates Foundation

Completed

Losartan for Patients With COVID-19 Requiring Hospitalization

Acute Respiratory Distress Syndrome | Corona Virus Infection | SARS-CoV Infection

United States
William Beaumont Hospitals

Terminated

Study of Immunomodulation Using Naltrexone and Ketamine for COVID-19 (SINK COVID-19)

Coronavirus Infections | COVID-19 | Acute Respiratory Distress Syndrome | Severe Acute Respiratory Syndrome (SARS)

United States
Denver Health and Hospital Authority
University of Colorado, Denver; University of Miami; Beth Israel Deaconess Medical... and other collaborators

Completed

Fibrinolytic Therapy to Treat ARDS in the Setting of COVID-19 Infection

Severe Acute Respiratory Syndrome | Respiratory Failure | Acute Respiratory Distress Syndrome

United States
Biocon Limited

Completed

Efficacy and Safety of Itolizumab in COVID-19 Complications

Covid19 | Acute Respiratory Distress Syndrome | Cytokine Release Syndrome

India
NMC Specialty Hospital

Completed

Expert Panel Statement for the Respiratory Management of COVID-19 Related Acute Respiratory Failure (C-ARF)

Covid19 | Acute Respiratory Distress Syndrome | Acute Respiratory Failure

United Arab Emirates
Chinese Academy of Sciences
Beijing YouAn Hospital

Unknown

Safety and Efficacy of CAStem for Severe COVID-19 Associated With/Without ARDS

COVID-19 | Acute Respiratory Distress Syndrome | Acute Lung Injury | Virus; Pneumonia

China
Biotest

Recruiting

Efficacy and Safety of Trimodulin (BT588) in Subjects With CAP Including COVID-19 Pneumonia (TRICOVID)

COVID-19 | Pneumonia | Acute Respiratory Distress Syndrome | Community-acquired Pneumonia | Respiratory Infection | Bacterial Pneumonia | Viral Pneumonia | Fungal Pneumonia

Belgium, Brazil, Latvia, Germany, Lithuania, South Africa, Argentina, Austria, France, Hungary, Slovakia, Turkey, Portugal, Spain
Centre Hospitalier Intercommunal de Toulon La Seyne...

Completed

Comparison of Non-invasive Oxygenation Strategies in Patients Admitted for Covid-19 Acute Respiratory Distress Syndrome (SONIC-19)

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

France
West Virginia University

Completed

Stellate Ganglion Block (SGB) for COVID-19 Acute Respiratory Distress Syndrome (ARDS)

COVID-19 | Acute Respiratory Distress Syndrome

United States
NYU Langone Health
Daxor Corporation

Completed

Blood Volume Assessment in COVID-19 and Bacterial Sepsis (BVAC19)

Covid19 | Bacterial Infections | Acute Respiratory Distress Syndrome | Bacterial Sepsis

United States
Organicell Regenerative Medicine

Available

Expanded Access to Zofin for Patients With COVID-19

Covid19 | Acute Respiratory Distress Syndrome | Corona Virus Infection | SARS (Severe Acute Respiratory Syndrome)
The University of Texas Health Science Center at...
The Claude D. Pepper Older Americans Independence Centers

Withdrawn

Effects of mTOR Inhibition With Sirolimus (RAPA) in Patients With COVID-19 to Moderate the Progression of ARDS (RAPA-CARDS)

Respiratory Failure | Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS) | Sars-CoV2

United States
Azienda Usl di Bologna
Lorenzo Gamberini

Completed

Risk Factors for Prolonged Invasive Mechanical Ventilation in COVID-19 Acute Respiratory Distress Syndrome

COVID-19 | Quality of Life | Sedation | Mechanical Ventilation | Complication of Treatment | Radiologic Increased Density of Lung

Italy
University of Calgary
Alberta Health services

Unknown

CORONA (COvid pRONe hypoxemiA): Prone Positioning for Hypoxemic COVID-19 Patients With Do-not-intubate Goals (CORONA)

COVID-19 | Acute Respiratory Distress Syndrome | ARDS | Severe Acute Respiratory Syndrome Coronavirus 2 | Hypoxemic Respiratory Failure

Canada
Azienda Sanitaria-Universitaria Integrata di Udine

Recruiting

Quality of Life After COVID-19 Related Acute respIratory Distress Syndrome Among ICU Survivors Patients in Italy: the ODISSEA Study. (ODISSEA)

Quality of Life | Covid19 | Post Traumatic Stress Disorder

Italy
Melaka Manipal Medical College

Completed

Knowledge, Attitude and Practice of Dental Students About COVID-19

Myalgia | Cough | Septic Shock | Bleeding | Fever | Acute Respiratory Distress Syndrome | Acute Lung Injury | Corona Virus Infection | Dyspnea

Malaysia
National Research Centre, Egypt
Egyptian Military Medical Services

Not yet recruiting

Clinical Assessment of Oral Lactoferrin as a Safe Antiviral and Immunoregulatory in Treating COVID-19 Disease (COVID-19_LF)

COVID-19 | Coronavirus Infection | SARS-CoV 2 | Acute Respiratory Distress Syndrome | Corona Virus Infection | Middle East Respiratory Syndrome (MERS)

Egypt
King's College Hospital NHS Trust
King's College London

Completed

SELF-BREATHE RCT for Chronic Breathlessness

Liver Failure | Cancer | Asthma | Renal Failure | Cystic Fibrosis | Chronic Heart Failure | Sickle Cell Disease | Interstitial Lung Disease | COPD | Dyspnea | Post COVID-19 | Bronchiectasis Adult

United Kingdom
Neuroganics LLC
Ramos Injury Law Firm

Recruiting

National Vaccine Adverse Event Reporting Survey and Etiology (NVAERS)

COVID-19 | Vaccine Adverse Reaction | Vaccine Reaction | Vasculitis | Neuritis | Thrombocytopenia | Influenza | Corona Virus Infection | Blood Clot | Guillain-Barré | Vaccine or Biological Substance, Unspecified Causing Adverse Effects in Therapeutic Use | GWAS | Genetic Sequencing

United States
Uppsala University

Recruiting

Mechanisms for Organ Dysfunction in Covid-19 (UMODCOVID19)

COVID-19 | Septic Shock | Acute Kidney Injury | Acute Respiratory Distress Syndrome | Organ Dysfunction Syndrome, Multiple | Organ Dysfunction Syndrome Sepsis

Sweden
Faculty Hospital Kralovske Vinohrady

Completed

The Epidemiology, Management and Comorbidities in Alopecia Areata in Czech Republic

Infections | Multiple Sclerosis | Autoimmune Diseases | Diabetes Mellitus, Type 1 | Rheumatoid Arthritis | Vaccine Reaction | Inflammatory Bowel Diseases | Psoriasis | Crohn Disease | Ulcerative Colitis | Down Syndrome | Atopic Dermatitis | Vitiligo | Alopecia Areata | COVID-19 Pandemic | Ankylosing Spondylitis | Lupus Erythematosus and other conditions

Czechia
OMNI Medical Services, LLC
OMNI Medical Services Inc

Recruiting

Outcomes Mandate National Integration With Cannabis as Medicine (OMNI-Can)

Depression | COVID-19 | Epilepsy | Multiple Sclerosis | Glaucoma | Cancer | Covid19 | Chronic Pain | Parkinson Disease | Inflammatory Bowel Diseases | Hepatitis C | Insomnia | HIV/AIDS | Amyotrophic Lateral Sclerosis | Fibromyalgia | Anxiety | Bipolar Disorder | Seizures | Crohn Disease | Traumatic Brain Injury | Ulcerative Colitis | Sickle... and other conditions

United States
Paul Szabolcs

Enrolling by invitation

Sequential Cadaveric Lung and Bone Marrow Transplant for Immune Deficiency Diseases (BOLT+BMT)

Chronic Granulomatous Disease (CGD) | Wiskott-Aldrich Syndrome | Severe Chronic Neutropenia | Severe Combined Immunodeficiency (SCID) | Immunodeficiency With Predominant T-cell Defect, Unspecified | Hyper IgE Syndromes | Hyper IgM Deficiencies | Mendelian Susceptibility to Mycobacterial Disease | Common...

United States
Sanford Health
National Ataxia Foundation; Beyond Batten Disease Foundation; Pitt Hopkins Research... and other collaborators

Recruiting

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford (CoRDS)

Mitochondrial Diseases | Retinitis Pigmentosa | Myasthenia Gravis | Eosinophilic Gastroenteritis | Multiple System Atrophy | Leiomyosarcoma | Leukodystrophy | Anal Fistula | Spinocerebellar Ataxia Type 3 | Friedreich Ataxia | Kennedy Disease | Lyme Disease | Hemophagocytic Lymphohistiocytosis | Spinocerebellar Ataxia... and other conditions

United States, Australia

Clinical Trials on Patient Admitted to Intensive Care Unit for COVID-19

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