Clinical Trials on Pediatric Liver Transplantation in Czechia

Total 183 results

Astellas Pharma Europe Ltd.

Completed

A Study to Compare How the Body Absorbs and Processes Two Different Formulations of the Anti-rejection Medication Tacrolimus (Advagraf® or Prograf®) in Children Receiving an Organ Transplant, and How Safe and Effective They Are Over a Longer Period of Time

Liver Transplantation | Kidney Transplantation | Heart Transplantation

Czechia, France, Italy, Poland, United Kingdom
Astellas Pharma Europe Ltd.

Active, not recruiting

Study to Compare the Pharmacokinetics of Tacrolimus in Stable Pediatric Allograft Recipients Converted From Prograf® to Advagraf®

Liver Transplantation | Kidney Transplantation | Heart Transplantation | Lung Transplantation | Intestine Transplantation

Belgium, Czechia, France, Germany, Italy, Poland, United Kingdom
Charles University, Czech Republic

Recruiting

The Role of Endothelial Glycocalyx in Kidney Transplantation

Kidney Transplantation

Czechia
Astellas Pharma Europe Ltd.

Completed

Study to Ascertain if Prolonged Release Tacrolimus (FK506E - MR4) is Safe and Effective When Used in the Long Term and in Combination With Other Immunosuppressive Drugs in Patients Who Have Received a Transplant

Liver Transplantation | Kidney Transplantation | Heart Transplantation

Spain, Australia, France, Germany, Canada, Italy, United Kingdom, Belgium, South Africa, Switzerland, Sweden, United States, Austria, Brazil, Czechia, Denmark, Finland, Hungary, Ireland, Mexico, Netherlands, New Zealand, Poland
Astellas Pharma Inc

Completed

A Study to Evaluate the Safety and Effectiveness of FK778 in Liver Transplant Patients

Liver Transplantation

United Kingdom, Germany, Spain, Belgium, Switzerland, Canada, Netherlands, Czech Republic, France, Hungary, Austria, Italy
Astellas Pharma Inc

Completed

Phase 3b Study to Evaluate Advagraf in Combination With Mycophenolate Mofetil and Basiliximab in Liver Transplantation (DIAMOND)

Liver Transplantation

Argentina, Austria, Belarus, Belgium, Brazil, Canada, Colombia, Czechia, Finland, France, Germany, Hungary, Ireland, Italy, Mexico, Poland, Romania, Russian Federation, South Africa, Spain, Sweden, Switzerland, United Kingdom
Wyeth is now a wholly owned subsidiary of Pfizer

Terminated

Study Evaluating of Calcineurin Inhibitor and Sirolimus (Rapamune) Treatment in Liver Transplant Recipients

Liver Transplantation

Italy, Belgium, Spain, France, Canada, Germany, United States, United Kingdom, Portugal, Czech Republic, Switzerland, Netherlands
Institute for Clinical and Experimental Medicine

Recruiting

rATG Versus rATG Combined With Intravenous Immunoglobulin (IVIG) Induction Immunosuppression in HLA Incompatible Transplantation (INHIBIT) (INHIBIT)

Kidney Transplantation

Czechia
Institute for Clinical and Experimental Medicine

Completed

IgG Antibodies After SARS-CoV-2 mRNA Vaccine in Kidney Transplantation (TASMANIA) (TASMANIA)

Kidney Transplantation

Czechia
Astellas Pharma Inc

Completed

A Study to Evaluate the Safety and Efficacy of FK506E (MR4) in Patients Undergoing Primary Liver Transplantation.

Liver Transplantation

France, Italy, Poland, Belgium, Spain, Germany, Switzerland, Canada, Finland, Brazil, Czech Republic, Australia, Norway, Sweden, United Kingdom, Ireland
Novartis Pharmaceuticals

Completed

Efficacy, Safety, Tolerability, Pharmacokinetics of Sotrastaurin-tacrolimus vs. Mycophenolic Acid-tacrolimus in de Novo Liver Transplant Patients

Liver Transplantation

Belgium, Germany, Italy, United States, Switzerland, Spain, Austria, Czechia, France, Argentina, Finland, Canada
University Hospital, Motol

Completed

Anaesthesiologic Considerations for Intraoperative ECMO Anticoagulation During Lung Transplantation

Lung Transplantation

Czechia
Brno University Hospital
Simulation Centre of the Faculty of Medicine of Masaryk University

Completed

Simulation-based Comparative Study on Efficiency of Ventilation During Paediatric Cardiopulmonary Resuscitation (PEDIVENT)

Simulated Pediatric CRP Ventilation

Czechia
University of Alberta
Natera, Inc.; One Lambda

Recruiting

Trifecta-Lung cfDNA-MMDx Study

Lung Transplantation

Canada, Australia, Austria, Czechia
Frantisek Saudek

Recruiting

Novel Method of Pancreatic Islet Transplantation Into the Omentum

Islets of Langerhans Transplantation

Czechia
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Concentration-controlled Everolimus to Eliminate or to Reduce Tacrolimus Compared to Tacrolimus in de Novo Liver Transplant Recipients (RAD)

Liver Transplantation

United States, Belgium, Colombia, Spain, Germany, Italy, Australia, Israel, France, Hungary, Netherlands, Argentina, Canada, Ireland, Sweden, Brazil, United Kingdom, Russian Federation, Czech Republic
General University Hospital, Prague

Recruiting

Ursodeoxycholic Acid in Patients With NAFLD - Clinical Observation (URSO)

Non-Alcoholic Fatty Liver Disease

Czechia
University of Ostrava
University Hospital Ostrava; University Hospital Olomouc; Palacky University

Recruiting

Bariatric Endoscopy and NAFLD

Obesity | NAFLD | Liver Steatosis | Liver Fibrosis

Czechia
Institute for Clinical and Experimental Medicine
St. Anne

Unknown

Assessment of Cardiac Allograft Vasculopathy by Optical Coherence Tomography (EARLY-OCT)

Disorder Related to Cardiac Transplantation

Czechia
General University Hospital, Prague

Recruiting

Lifestyle Modification in the Treatment of NAFLD.

NAFLD

Czechia
Military University Hospital, Prague
University of Chemistry and Technology, Prague

Unknown

Novel Molecular Spectrometric Biomarkers in Blood Plasma as an Early Diagnostic Tool in HCC

Hepatocellular Carcinoma | Cirrhosis, Liver | Liver Cancer

Czechia
Thomayer University Hospital
Masaryk University

Recruiting

Czech AATD Registry

Alpha-1-antitrypsin Deficiency

Czechia
University Hospital Ostrava

Active, not recruiting

Bariatric Endoscopy and NAFLD

Obesity | NAFLD | Liver Steatosis | Liver Fibrosis

Czechia
Bristol-Myers Squibb

Completed

An Investigational Study to Evaluate Experimental Medication BMS-986036 in Participants With Different Levels of Kidney Function

NAFLD | Nonalcoholic Fatty Liver Disease | Nonalcoholic Steatohepatitis

Hungary, Czechia
General University Hospital, Prague

Completed

Polyunsaturated Fatty Acids in Patients With NAFLD.

NAFLD

Czechia
Astellas Pharma Inc
Astellas Pharma Europe B.V.

Completed

A Study to Evaluate FK778 in Kidney Transplant Patients

Kidney Transplantation | Renal Transplantation | Transplantation, Kidney | Grafting, Kidney | Transplantation, Renal

Belgium, Germany, Spain, Sweden, Italy, Switzerland, United Kingdom, Austria, France, Poland, Czech Republic, Netherlands
University Hospital, Motol

Terminated

Point-of-care Management of Coagulopathy in Lung Transplantation

Lung Transplantation

Czechia
Hoffmann-La Roche

Completed

A Study to Investigate the Effect of Impaired Hepatic Function on the Pharmacokinetics of Entrectinib in Volunteers With Different Levels of Hepatic Function

Hepatic Insufficiency

Hungary, Czechia, Slovakia
Bristol-Myers Squibb

Completed

An Investigational Study of BMS-986165 in Participants With Normal Liver Function and Participants With Mild to Severe Liver Damage

Healthy Volunteers | Liver Dysfunction

Czechia, Hungary, Slovakia
Astellas Pharma Inc

Completed

Comparing Efficacy and Safety of Tacrolimus With Steroids or Monoclonal Anti-IL2R Antibody in Hepatitis C Virus (HCV) Positive Liver Transplant Patients (CHASE)

Liver Transplantation | Hepatitis C

Italy, France, Germany, Sweden, United Kingdom, Poland, Spain, Czech Republic
University Hospital Ostrava

Completed

Seroprevalence of the Anti-SARS-CoV-2 Antibodies (Causing COVID-19) in Kidney Transplant Recipients in Severely Affected Region (SECOVtx)

COVID-19 Pandemic | Transplantation, Kidney

Czechia
Faculty Hospital Kralovske Vinohrady

Recruiting

CArdioMetabolic Prevention in Adolescents (CAMP)

Body Weight Changes | Adolescent Obesity | Life Style, Healthy | Cardiometabolic Syndrome

Czechia
Institute for Clinical and Experimental Medicine

Completed

Molecular Markers of Acute Kidney Injury in Elderly Deceased Donors (MoliDon)

Kidney Transplantation | Acute Kidney Injury

Czechia
Prof. Dr. Petra Reinke

Completed

Prospective Donor Specific T Response Measurment for IS Minimization in de Novo Renal Transplantation

Disorder Related to Renal Transplantation | Effects of Immunosuppressant Therapy

Germany, France, Spain, Czechia, Netherlands, United Kingdom
University Hospital Ostrava
University of Ostrava

Completed

Bariatric Surgery and Fatty Liver Disease

Hypertension | Diabetes | Morbid Obesity

Czechia
Astellas Pharma Inc

Completed

Mycophenolate Mofetil (MMF) Discontinuation From a Tacrolimus/MMF/Steroid Triple Regimen After Kidney Transplantation (DISTAMP)

Kidney Transplantation

Poland, Czech Republic, Hungary, Slovakia
Hoffmann-La Roche

Completed

Effect of Hepatic Impairment on the Pharmacokinetics of Alectinib

Hepatic Impairment

Czechia, Slovakia
Masaryk University
Brno University Hospital; Roche s.r.o.

Recruiting

Pediatric Prospective Personalized Immune and Target Identification Trial (PPROSPERITIT)

Central Nervous System Neoplasms | Pediatric Cancer | Tumor, Brain | GEN1 Gene Mutation

Czechia
Takeda

Completed

A Study to Evaluate the Effect of Hepatic Impairment on the Single Dose Pharmacokinetics (PK) of Intravenous TAK-954

Healthy Volunteers | Hepatic Impairment

Czechia, Slovakia
Mitsubishi Tanabe Pharma Corporation

Completed

PK Study in Subjects With Severe Hepatic Impairment (MCI-186-E05 HP)

Healthy | Severe Hepatic Impairment

Czechia, Hungary, Slovakia
Novartis Pharmaceuticals

Completed

Efficacy, Safety and Tolerability of AEB071 Versus Cyclosporine in the Novo Renal Transplant Recipients (AEB071)

Kidney Transplantation

Germany, Switzerland, Singapore, Colombia, Argentina, Slovakia, Australia, Austria, Belgium, Brazil, Czech Republic, France, Italy, Netherlands, Norway, Spain, Taiwan
Astellas Pharma Inc

Completed

Conversion Study From Cyclosporine to FK506MR Based Immunosuppression in Kidney Transplant Subjects (CONCERTO)

Transplantation

France, Italy, Poland, Germany, Spain, Belgium, Switzerland, Finland, Czech Republic, Hungary, Austria, Denmark, Sweden
Astellas Pharma Inc

Completed

Comparing Efficacy and Safety of Steroid Withdrawal With Tacrolimus and MMF With Induction in Children After Kidney Transplantation (TWIST)

Kidney Transplantation

Belgium, Italy, Taiwan, France, South Africa, Turkey, Germany, United Kingdom, Hungary, Czech Republic, Romania, Sweden, Poland, Israel
Novartis Pharmaceuticals

Completed

Efficacy and Safety of AEB071 Versus Cyclosporine in de Novo Renal Transplant Recipients

Kidney Transplantation

Belgium, Taiwan, Italy, Germany, Spain, Switzerland, Australia, Singapore, Norway, Netherlands, Colombia, Argentina, Brazil, Austria, Slovakia, France, Czech Republic
Astellas Pharma Inc

Completed

To Compare the Efficacy and Safety of a Therapy of Tacrolimus With Sirolimus or MMF in Kidney Transplantation. (RESTORE)

Kidney Transplantation

Belgium, France, Germany, Spain, Australia, Italy, Austria, Romania, United Kingdom, Poland, Hungary, Sweden, Netherlands, Czech Republic
Bristol-Myers Squibb

Completed

Study of Belatacept in Subjects Who Are Undergoing a Renal Transplant (BENEFIT-EXT)

Renal Transplantation

United States, Argentina, Germany, Italy, Chile, Spain, Brazil, Sweden, Belgium, France, Hungary, Australia, South Africa, Austria, Canada, United Kingdom, Poland, Czechia, Norway
Pfizer

Completed

Collection of Follow-up Data From CP-690,550-treated Kidney Transplant Recipients

Kidney Transplantation

United States, Australia, France, Brazil, Germany, Italy, Canada, Spain, Netherlands, Belgium, Czech Republic, Norway
GlaxoSmithKline

Completed

A Study to Assess the Effects of Fluticasone Furoate and GW642444M Combination in Healthy Subjects and in Subjects With Mild, Moderate or Severe Hepatic Impairment.

Asthma

Czechia, Slovakia
Pfizer

Completed

Study of PF-05221304 in Subjects With Varying Degrees of Hepatic Impairment

Hepatic Impairment

United States, Belgium, Czechia, Slovakia
Astellas Pharma Inc

Completed

A Study to Assess the Efficacy and Safety of Alefacept in Kidney Transplant Recipients

De Novo Kidney Transplantation

Belgium, France, Netherlands, Spain, Sweden, Austria, Italy, Germany, United Kingdom, Hungary, Poland, Czech Republic

Clinical Trials on Pediatric Liver Transplantation in Czechia

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