Clinical Trials on Pelvic Floor; Weak in Ireland

Total 51 results

EvergreenHealth
The Cleveland Clinic

Completed

A Trial of Pelvic Floor Chemodenervation in Patients Undergoing Physical Therapy for High Tone Pelvic Floor Dysfunction

Pelvic Pain | Dyspareunia | Pelvic Floor Dysfunction

United States
St Vincent's University Hospital, Ireland

Completed

A Review of Functional and Surgical Outcomes of Gynaecological Reconstruction in the Context of Pelvic Exenteration

Pelvic Cancer

Ireland
Women and Infants Hospital of Rhode Island

Completed

Computerized-Adaptive Testing: Feasibility In Women With Pelvic Floor Disorders (CAT) (CAT)

Urinary Incontinence

United States
University College Cork

Unknown

Trial for the Treatment of Pelvic and Back Pain in Pregnancy (GRIP)

Pelvic Girdle Pain | Symphysio Pubic Dysfunction

Ireland
St Vincent's University Hospital, Ireland
PelvEx

Completed

Perineal Flap Reconstruction Following Surgery for Advanced Pelvic Malignancy

Rectal Cancer | Pelvic Cancer | Flap Necrosis | Flap Disorder | Perioperative Complication | Flap Ischemia

Ireland
University of Texas Southwestern Medical Center
Pfizer; University of Alabama at Birmingham; Women and Infants Hospital of Rhode...

Completed

Investigation to Minimize Prolapse Recurrence of the Vagina Using Estrogen (IMPROVE)

Pelvic Organ Prolapse | Pelvic Floor Disorders | Cystocele | Uterine Prolapse | Vaginal Vault Prolapse | Vaginal Prolapse | Urogenital Prolapse

United States
St Vincent's University Hospital, Ireland

Recruiting

A Contemporary Review of Surgical Approaches in Pelvic Exenterative Surgery

Locally Advanced Rectal Cancer | Pelvic Exenteration | Advanced Pelvic Malignancy

Ireland
Femke van Zanten

Unknown

Prospective Assessment of Robotic Sacrocolpopexy: a European Multicentric Cohort (PARSEC) (PARSEC)

Pelvic Organ Prolapse

Ireland
Landspitali University Hospital
University of Iceland

Unknown

A Feasibility Study on the Value of Pelvic Floor Training After Pelvic Organ Prolapse Surgery

Pelvic Organ Prolapse

Iceland
Amsterdam UMC, location VUmc

Active, not recruiting

Enhanced Perioperative Care for the Prevention of Colorectal Anastomotic Leakage (DOUBLE CHECK)

Intraoperative Awareness | Anastomotic Leak Rectum | Anastomotic Leak Small Intestine | Anastomotic Leak Large Intestine

Belgium, Netherlands
University Hospital, Geneva
University College Dublin; Oxford University Hospitals NHS Trust

Completed

Decreasing Leak Rate in Colorectal Surgery Using Near Infra-red (NIR) Imaging

Anastomotic Leak

Ireland, Italy, Switzerland, United Kingdom
Cork University Hospital
University College Cork

Completed

Trans-perineal Trigger Point Dry Needling for Chronic Pelvic Pain

Dyspareunia

Ireland
Wake Forest University Health Sciences
Foundation for Female Health Awareness

Completed

Retropubic vs. Single-Incision Mid-Urethral Sling for Stress Urinary Incontinence

Stress Urinary Incontinence | Pelvic Floor Disorders

United States
Johnson & Johnson Vision Care, Inc.

Completed

Clinical Evaluation of Lapsed Contact Lens Wearers Who Are Re-fit Into Senofilcon A Contact Lenses

Lapsed Contact Lens Wear

United States
Asepticys LLC

Completed

A Safety and Effectiveness Study of a New Multi-Purpose Contact Lens Care Solution

Contact Lens Wear

United States
Women and Infants Hospital of Rhode Island
Johns Hopkins University; University of South Florida; Northwestern University; University of Alabama at Birmingham and other collaborators

Recruiting

Race, Ethnicity, Socioeconomic Status and Prolapse-rElated Decisional ConflicT (RESPECT)

Pelvic Organ Prolapse | Prolapse, Urogenital

United States
Reckitt Benckiser Healthcare (UK) Limited

Completed

Clinical Investigation to Assess the Acid Neutralisation Activity of a Calcite Chewing Gum

Esophagitis | Gastro Oesophageal Reflux Disease

Ireland
Lifespan

Completed

POCUS Assessment of Bladder Fullness for Girls Awaiting Radiology-Performed Transabdominal Pelvic Ultrasound

Abdominal Pain | Pelvic Pain

United States
AstraZeneca

Completed

A Phase II Study of AZD4877 (a Novel Anti-mitotic Agent) in Advanced Bladder Cancer

Bladder Cancer | Urethra Cancer | Ureter Cancer | Renal Pelvis Cancer | Transitional Cell Bladder Cancer

United States, Spain, United Kingdom, Germany, Canada
Glasgow Caledonian University
University of Otago; South Glasgow University Hospitals NHS Trust; University... and other collaborators

Completed

Multi-centre Randomised Controlled Trial of Pelvic Floor Muscle Training for Prolapse (POPPY)

Pelvic Organ Prolapse

United Kingdom, Australia, Ireland, New Zealand
The Cleveland Clinic
Stanford University; The Christ Hospital; Medstar Health Research Institute; Women... and other collaborators

Completed

Vaginal Uphold Hysteropexy and Laparoscopic Sacral Hysteropexy for the Treatment of Uterovaginal Pelvic Organ Prolapse (VAULT)

Pelvic Organ Prolapse

United States, Canada
Duramed Research

Completed

A Study to Evaluate the Efficacy of Seasonique for the Treatment of Cyclic Pelvic Pain

Dysmenorrhea

United States
Connolly Hospital Blanchardstown
Royal College of Surgeons, Ireland; European Society for Trauma and Emergency... and other collaborators

Completed

Multicentric Point of Care UltraSound by Surgeons Trial (POCUSS)

Diverticulitis, Colonic | Biliary Disease | Gallstone; Cholecystitis, Acute | Abscess Pelvic

Ireland, Italy, Portugal, Spain
AbbVie

Terminated

A Study of Women Receiving Standard of Care (SOC) for the Treatment of Pelvic Pain Due to Suspected or Confirmed Endometriosis and the Impact on the Disease or Symptom Progression.

Endometriosis | Dysmenorrhea | Chronic Pelvic Pain

United States
Exact Sciences Corporation

Completed

Blood Sample Collection to Evaluate Biomarkers in Subjects With Untreated Solid Tumors

Kidney Cancer | Stomach Cancer | Breast Cancer | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Lung Cancer | Prostate Cancer | Bladder Cancer | Liver Cancer | Renal Pelvis Cancer | Uterine Cancer

United States
NICHD Pelvic Floor Disorders Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Active, not recruiting

Apical Suspension Repair for Vault Prolapse In a Three-Arm Randomized Trial Design (ASPIRe)

Visceral Prolapse

United States
National Cancer Institute (NCI)

Recruiting

Comparing the New Anti-cancer Drug Eribulin With Chemotherapy Against the Usual Chemotherapy Alone in Metastatic Urothelial Cancer

Metastatic Bladder Urothelial Carcinoma | Metastatic Renal Pelvis Urothelial Carcinoma | Metastatic Ureter Urothelial Carcinoma | Metastatic Urethral Urothelial Carcinoma | Metastatic Urothelial Carcinoma | Stage IV Bladder Cancer AJCC v8 | Stage IV Renal Pelvis Cancer AJCC v8 | Stage IV Ureter Cancer... and other conditions

United States
National Cancer Institute (NCI)

Completed

Gemcitabine Hydrochloride and Cisplatin With or Without Bevacizumab in Treating Patients With Advanced Urinary Tract Cancer

Metastatic Prostate Carcinoma | Metastatic Bladder Urothelial Carcinoma | Metastatic Renal Pelvis Urothelial Carcinoma | Metastatic Ureter Urothelial Carcinoma | Metastatic Urethral Urothelial Carcinoma | Metastatic Urothelial Carcinoma | Stage IV Bladder Urothelial Carcinoma AJCC v7 | Stage IV Renal... and other conditions

United States, Puerto Rico
Takeda

Completed

Determination of a Questionnaire After Treatment With Pantoprazole at Full Dose and Half Dose in Adult Patients With Symptoms of Acid Reflux (Gastroesophageal Reflux Disease) (BY1023/UK-506)

Gastroesophageal Reflux | GERD | GORD

United Kingdom
University of Chicago
Myovant Sciences GmbH

Recruiting

Surgical Myomectomy Followed by Oral Myfembree Versus Standard of Care Trial (SOUL) (SOUL)

Pelvic Pain | Metrorrhagia | Leiomyoma | Menorrhagia

United States
Brown University

Recruiting

Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA

Arthritis | Chronic Pain | Chronic Low-back Pain | Irritable Bowel Syndrome | Fibromyalgia | Acute Pain | Trauma, Multiple | Neuropathic Pain | Temporomandibular Joint Disorders | Post Operative Pain | Chronic Pain Syndrome | Chronic Shoulder Pain | Painful Diabetic Neuropathy | Chronic Migraine | Painful Bladder Syndrome and other conditions

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing MK-3475 (Pembrolizumab) After Surgery for Localized Muscle-Invasive Bladder Cancer and Locally Advanced Urothelial Cancer (AMBASSADOR)

Stage III Bladder Urothelial Carcinoma AJCC v6 and v7 | Stage III Ureter Cancer AJCC v7 | Locally Advanced Bladder Urothelial Carcinoma | Locally Advanced Ureter Urothelial Carcinoma | Locally Advanced Urothelial Carcinoma | Localized Renal Pelvis and Ureter Urothelial Carcinoma | Stage II Bladder... and other conditions

United States, Guam
AstraZeneca

Completed

Esomeprazole (NEXIUM) vs. Surgery (LOTUS)

Gastroesophageal Reflux

Italy, Sweden, Germany, Denmark, Finland, Norway, Netherlands, Austria, Belgium, United Kingdom, France, Iceland
Shire

Completed

Selective 5-HT4 Receptor Agonist and Proton Pump Inhibitor (PPI) in Subjects With Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease

United States, Czechia, Germany, Latvia, Poland, Romania
Takeda

Completed

Comparison of Dexlansoprazole MR to Placebo on the Ability to Maintain Healing in Subjects With Healed Erosive Esophagitis

Esophagitis, Peptic | Esophagitis, Reflux

United States
Medical Research Council

Completed

Fluorouracil in Treating Patients With Recurrent or Metastatic Bladder Cancer

Bladder Cancer | Transitional Cell Cancer of the Renal Pelvis and Ureter | Urethral Cancer

Canada, United Kingdom, Norway, New Zealand, Netherlands, South Africa, Brazil, Finland
Takeda

Completed

Efficacy and Safety of Dexlansoprazole MR and Lansoprazole on Healing of Erosive Esophagitis

Esophagitis, Peptic | Esophagitis, Reflux

United States, Poland, Bulgaria, India, Canada, Peru, Russian Federation, Australia, New Zealand, Czech Republic, Slovakia, South Africa, Latvia, Lithuania, Colombia, Germany
AstraZeneca

Completed

NEXIUM® in the Treatment of Moderate and Severe Erosive Esophagitis

Gastroesophageal Reflux Disease | Erosive Esophagitis | Reflux Esophagitis

United States
Ironwood Pharmaceuticals, Inc.

Completed

A Trial of IW-3718 for 8 Weeks in Patients With Symptomatic Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease

United States
Eisai Inc.

Completed

Rabeprazole Extended-Release 50 mg Versus Esomeprazole 40 mg for Healing and Symptomatic Relief of Mild to Moderate Erosive Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease (GERD)

United States
AstraZeneca

Completed

Local Phase IV, Gastroesophageal Reflux Disease (GERD) Sleep Study US

Gastroesophageal Reflux Disease

United States
Ironwood Pharmaceuticals, Inc.

Terminated

A Trial of IW-3718 for 8 Weeks in Patients With Persistent Gastroesophageal Reflux Disease (GERD) Receiving Proton Pump Inhibitors (PPIs)

Gastroesophageal Reflux Disease (GERD)

Canada, United States
Ironwood Pharmaceuticals, Inc.

Completed

Trial of IW-3718 for 8 Weeks in Patients With Persistent Gastroesophageal Reflux Disease (GERD) Receiving Proton Pump Inhibitors (PPIs)

Gastroesophageal Reflux Disease (GERD)

United States, Canada
Eisai Inc.

Completed

Comparing the Efficacy, Safety, and Tolerability of Rabeprazole ER 50 mg With Placebo in Subjects With Symptomatic Gastroesophageal Reflux Disease (sGERD)

Symptomatic Gastroesophageal Reflux Disease (sGERD)

United States
Takeda

Completed

Safety and Efficacy of Dexlansoprazole Modified Release Formulation to Treat Heartburn

Gastroesophageal Reflux Disease

United States
AbbVie

Recruiting

Study Of Oral Elagolix Tablets In Combination With Combined Oral Contraceptive Capsules/Tablets To Assess Dysmenorrhea Response In Adult Female Participants With Endometriosis And Associated Moderate To Severe Pain

Endometriosis

United States, Puerto Rico
Eastern Cooperative Oncology Group
National Cancer Institute (NCI); Cancer and Leukemia Group B

Completed

Two-Drug Combination Chemotherapy Compared With Four-Drug Combination Chemotherapy in Treating Patients With Advanced Cancer of the Urothelium

Bladder Cancer | Transitional Cell Cancer of the Renal Pelvis and Ureter | Urethral Cancer

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Active, not recruiting

Trying to Find the Correct Length of Treatment With Immune Checkpoint Therapy (IMAGINE)

Metastatic Bladder Urothelial Carcinoma | Metastatic Renal Pelvis Urothelial Carcinoma | Metastatic Ureter Urothelial Carcinoma | Metastatic Urethral Urothelial Carcinoma | Metastatic Urothelial Carcinoma | Locally Advanced Bladder Urothelial Carcinoma | Locally Advanced Renal Pelvis Urothelial... and other conditions

United States
European Organisation for Research and Treatment...
National Cancer Institute (NCI); Medical Research Council; NCIC Clinical Trials... and other collaborators

Completed

Cisplatin Plus Gemcitabine With or Without Paclitaxel in Treating Patients With Stage IV Urinary Tract Cancer

Bladder Cancer | Transitional Cell Cancer of the Renal Pelvis and Ureter | Urethral Cancer

France, Spain, Canada, United States, Denmark, Poland, Belgium, Germany, Netherlands, Italy, United Kingdom, Austria, Australia, Hungary, Slovakia, Israel
Eli Lilly and Company

Completed

An Ovarian, Primary Peritoneal or Fallopian Tube Cancer Study for Patients That Have Not Received Prior Chemotherapy

Genital Neoplasms, Female | Ovarian Neoplasms | Fallopian Tube Neoplasms | Peritoneal Neoplasms | Pelvic Neoplasms

United States, Puerto Rico

Clinical Trials on Pelvic Floor; Weak in Ireland

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