Clinical Trials on Pelvic Malignancy in South Africa

Total 354 results

University of Johannesburg

Completed

The Efficacy of Viburnum Opulus 3X in the Treatment of Primary Dysmenorrhea

Dysmenorrhea

South Africa
Sherman College of Straight Chiropractic

Completed

A Comparison of Radiographic and Visual Analysis Methods for Determining Pelvic Misalignments.

Gonstead, Chiropractic, Pelvic Analysis

United States
Hoffmann-La Roche

Completed

An Open-Label Study of Zelboraf (Vemurafenib) in Patients With Braf V600 Mutation Positive Metastatic Melanoma

Malignant Melanoma

South Africa
Bayer

Completed

Uncomplicated Pelvic Inflammatory Disease. Treatment With Moxifloxacin. (MAIDEN)

Pelvic Inflammatory Disease

Germany, Italy, France, Hungary, Sweden, Poland, South Africa, Russian Federation, Finland, Denmark, Lithuania, United Kingdom, Greece
Sheffield Teaching Hospitals NHS Foundation Trust

Unknown

PTNS as a Treatment for Tenesmus

Pelvic Floor Disorders

United Kingdom
University of Sheffield
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Does Using a 'Virtual Clinic' in Urogynaecology Improve Patient Experience and Reduce Cost?

Pelvic Floor Disorders

United Kingdom
Ethicon, Inc.

Completed

A Surgical Simulation Study to Evaluate the Safety of a Device Mechanism as Treatment for Vaginal Apical Prolapse

Pelvic Organ Prolapse

Australia
Bien-Willner Physicians Group PA
No One Left Alone; Carolina Blood and Cancer Care Associates

Not yet recruiting

Molecular Services and EMR-Lab Integration Application (ELIA) for Reducing Healthcare Disparities in Cancer Patients

Advanced Cancer | Myeloid Malignancy | Solid Tumor, Adult

United States
University of Vermont

Completed

Changing the Paradigm of In-Hospital Cardiopulmonary Resuscitation With Informed Assent

Advanced Malignancy | Oxygen Dependent COPD

United States
University of South Australia

Completed

Hypnotic Intervention for Women With Chronic Pelvic Pain

Chronic Pain | Pelvic Pain | Psychological | Hypnosis, Animal

Australia
Wake Forest University Health Sciences
Boston Scientific Corporation

Recruiting

Single-incision Versus Retropubic Mid-Urethral Sling (Solyx) for SUI During Minimally Invasive Sacrocolpopexy (SASS)

Stress Urinary Incontinence | Pelvic Floor Disorders

United States, South Africa
Hoffmann-La Roche

Completed

A Pharmacokinetics (PK) Study to Investigate the Effect of Rifampin on PK of Vemurafenib (Zelboraf)

Malignant Melanoma, Neoplasms

United States, South Africa, Croatia, Brazil, Egypt
Akesobio Australia Pty Ltd

Recruiting

A Study of AK112, a PD-1/VEGF Bispecific Antibody, for Advanced Solid Tumors

Neoplasms Malignant

Australia
University of Adelaide

Unknown

The Progression From Dysmenorrhoea to Chronic Pelvic Pain

Chronic Pain | Pelvic Pain | Dysmenorrhoea

Australia
Sheffield Teaching Hospitals NHS Foundation Trust
Ipsen

Completed

Decapeptyl SR With Livial Add Back Therapy in the Management of Chronic Cyclical Pelvic Pain in Pre Menopausal Women

Endometriosis

United Kingdom
AmMax Bio, Inc.

Completed

A Study of AMG 820 in Subjects With Advanced Solid Tumors

Cancer | Advanced Solid Tumors | Oncology | Tumors | Advanced Malignancy | Oncology Patients

United States
Medical University of South Carolina

Completed

Timing of Prophylactic Antibiotics for Cesarean Sections

Wound Infection | Endometritis

United States
Hoffmann-La Roche

Completed

A Pharmacokinetics Study to Investigate the Effect of Vemurafenib on Digoxin in Patients With BRAFV600 Mutation-Positive Metastatic Melanoma

Malignant Melanoma, Neoplasms

Russian Federation, Korea, Republic of, Israel, South Africa, Belarus
BioSyngen Pte Ltd

Unknown

A Study of Syngenon (BSG-001) for Inhalation in Subjects With Malignant Pleural Effusion and/or Malignant Ascites

Malignant Ascites | Malignant Pleural Effusion

Australia
Astellas Pharma Inc
Seagen Inc.

Completed

A Study of Enfortumab Vedotin for Patients With Locally Advanced or Metastatic Urothelial Bladder Cancer (EV-201)

Urologic Neoplasms | Urinary Bladder Neoplasms | Carcinoma, Transitional Cell | Ureteral Neoplasms | Urothelial Cancer | Urethral Neoplasms | Renal Pelvis Neoplasms

United States, Korea, Republic of, Spain, France, Germany, Italy, Japan, Netherlands
Edwards Lifesciences

Completed

Assisted Fluid Management IDE Study (AFM)

Abdominal Surgery | Pelvic Surgery | Non-Cardiac/ Non-Thoracic Surgery | Major Peripheral Vascular Surgery

United States
Akeso

Not yet recruiting

A Study to Evaluate the Safety, Pharmacokinetics, and Antitumor Activity of AK114

Metastasis | Advanced or Metastatic Solid Tumors | Malignancy

Australia
Akesobio Australia Pty Ltd

Completed

A Study to Evaluate the Safety, Pharmacokinetics, and Antitumor Activity of AK117 as Monotherapy or in Combination With AK104

Neoplasms Malignant

Australia
Clover Biopharmaceuticals AUS Pty Ltd

Completed

Study With SCB-313 (Recombinant Human TRAIL-Trimer Fusion Protein) for Treatment of Malignant Pleural Effusions

Malignant Pleural Effusions

Australia
Hoffmann-La Roche

Completed

A Study of Continued Treatment Among Participants Who Have Responded to Peginterferon Alfa-2a (Pegasys®) or Recombinant Interferon Alfa-2a (Roferon-A®) in Prior Clinical Studies

Renal Cell Carcinoma | Chronic Myelogenous Leukemia | Malignant Melanoma

Canada, India, Bulgaria, Russian Federation, Spain, South Africa, Slovakia
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of the Anti-cancer Drug, Cabozantinib, to the Usual Immunotherapy Treatment, Avelumab, in Patients With Metastatic Urothelial Cancer, MAIN-CAV Study

Advanced Bladder Urothelial Carcinoma | Advanced Ureter Urothelial Carcinoma | Metastatic Bladder Urothelial Carcinoma | Metastatic Renal Pelvis Urothelial Carcinoma | Metastatic Ureter Urothelial Carcinoma | Metastatic Urethral Urothelial Carcinoma | Stage III Bladder Cancer AJCC v8 | Stage III... and other conditions

United States, Canada
Astellas Pharma Global Development, Inc.
Merck Sharp & Dohme LLC; Seagen Inc.

Active, not recruiting

A Study of Enfortumab Vedotin Alone or With Other Therapies for Treatment of Urothelial Cancer (EV-103)

Urologic Neoplasms | Urinary Bladder Neoplasms | Carcinoma, Transitional Cell | Ureteral Neoplasms | Urothelial Cancer | Urethral Neoplasms | Renal Pelvis Neoplasms

United States, Italy, Spain, Canada, France, Puerto Rico
Mereo BioPharma
Novartis

Terminated

A Safety & Efficacy Study of BGS649 in Women With Refractory Endometriosis

Pelvic Pain Associated With Refractory Endometriosis

United States, Puerto Rico
ASTORA Women's Health

Terminated

Collection of Long Term Patient Outcomes Data Following Implantation of AMS Surgical Devices (CAPTURE)

Pelvic Organ Prolapse | Female Stress Incontinence

United States, Spain, Slovenia, France, United Kingdom, Canada, Germany, South Africa
Amgen

Completed

A Phase 1 First-in-Human Study Evaluating AMG 900 in Advanced Solid Tumors

Cancer | Advanced Solid Tumors | Solid Tumors | Tumors | Advanced Malignancy

United States, Australia
Boston Scientific Corporation

Completed

Xenform Postmarket Surveillance Study (Xenform)

Pelvic Organ Prolapse

United States
Wales Cancer Trials Unit
Velindre NHS Trust; June Hancock Mesothelioma Research Fund; Velindre Cancer...

Unknown

A Phase II Trial to Assess TroVax® Plus Chemotherapy in Patients With Malignant Pleural Mesothelioma (SKOPOS)

Mesothelioma | Malignant | Pleural

United Kingdom
Boston Scientific Corporation

Completed

Uphold LITE Post-Market Surveillance Study (Uphold LITE)

Pelvic Organ Prolapse

United States
ASTORA Women's Health

Completed

Pelvic Floor Repair Systems for Prolapse Repair (PROPEL)

Pelvic Organ Prolapse

United States, Belgium, France, Germany, Netherlands, Spain, United Kingdom
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Recruiting

Collection of Research Data and Samples From Patients Who Experience Immunotherapy Side Effects

Malignancy

United States
Virttu Biologics Limited

Completed

Intrapleural Administration of HSV1716 to Treat Patients With Malignant Pleural Mesothelioma. (1716-12)

Malignant Pleural Mesothelioma

United Kingdom
Millennium Pharmaceuticals, Inc.

Terminated

A Dose Escalation Study of MLN7243 (TAK-243) in Adult Participants With Advanced Solid Tumors

Advanced Malignant Solid Tumors

United States
Bayer

Completed

Effect of a New Oral Contraceptive Pill on Hormone Related Symptoms Such as Pelvic Pain and Headache

Headache | Pelvic Pain | Oral Contraceptive

Finland, France, Switzerland, Australia, Germany, Thailand, Mexico, United Kingdom, Spain
The Netherlands Cancer Institute
Bristol-Myers Squibb

Active, not recruiting

Optimal Neo-adjuvant Combination Scheme of Ipilimumab and Nivolumab (OpACIN-neo)

Malignant Melanoma Stage III

Austria, Netherlands, Australia, Sweden
AbbVie

Terminated

A Study of Women Receiving Standard of Care (SOC) for the Treatment of Pelvic Pain Due to Suspected or Confirmed Endometriosis and the Impact on the Disease or Symptom Progression.

Endometriosis | Dysmenorrhea | Chronic Pelvic Pain

United States
Steba Biotech S.A.
PrimeVigilance; ICON plc

Recruiting

ENdoluminal LIGHT ActivatED Treatment of Upper Tract Urothelial Cancer (ENLIGHTED) Study (UCM301)

Transitional Cell Cancer of Renal Pelvis and Ureter

United States, Israel, Spain, Italy, France, Germany, Austria
Exact Sciences Corporation

Completed

Blood Sample Collection to Evaluate Biomarkers in Subjects With Untreated Solid Tumors

Kidney Cancer | Stomach Cancer | Breast Cancer | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Lung Cancer | Prostate Cancer | Bladder Cancer | Liver Cancer | Renal Pelvis Cancer | Uterine Cancer

United States
Incyte Corporation

Terminated

Efficacy and Safety of Pemigatinib in Previously Treated Locally Advanced/Metastatic or Surgically Unresectable Solid Tumor Malignancies Harboring Activating FGFR Mutations or Translocations (FIGHT-207)

Solid Tumor Malignancy

United States, France, United Kingdom, Italy, Korea, Republic of, Japan, Spain, Israel, Denmark, Germany, Switzerland
AstraZeneca

Completed

A Study to Prevent Rebleeding After Initial Successful Primary Endoscopic Haemostasis of a Bleeding Peptic Ulcer

Gastrointestinal Hemorrhage

Sweden, Russian Federation, South Africa, Spain, Turkey, United Kingdom, Germany, Romania, Finland, Norway, Hong Kong, Austria, Denmark, Netherlands, Greece, France
Asbestos Diseases Research Foundation
EnGeneIC Limited

Completed

MesomiR 1: A Phase I Study of TargomiRs as 2nd or 3rd Line Treatment for Patients With Recurrent MPM and NSCLC

Non-Small Cell Lung Cancer | Malignant Pleural Mesothelioma

Australia
National Cancer Institute (NCI)

Recruiting

Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene

Malignant Solid Neoplasm

United States
Genentech, Inc.

Completed

A Study Evaluating Targeted Therapies in Participants Who Have Advanced Solid Tumors With Genomic Alterations or Protein Expression Patterns Predictive of Response (MyTACTIC)

Advanced Unresectable or Metastatic Solid Malignancy

United States
Vyriad, Inc.

Completed

Ph1 Administration of VSV-IFNβ-NIS Monotherapy and in Combination With Avelumab in Pts With Refractory Solid Tumors

Malignant Solid Tumour

United States
Johns Hopkins University
Medical University of South Carolina; University of Colorado, Denver; All India... and other collaborators

Completed

EUS-Guided Biliary Drainage in Patients With Inoperable Malignant Distal Biliary Obstruction and Failed ERCP: a Prospective Feasibility Multicenter Trial

Malignant Distal Biliary Obstruction

United States, India, Japan, Italy, Netherlands
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Safety and Efficacy of ERB-041 on Reduction of Symptoms Associated With Endometriosis in Reproductive-Aged Women

Endometriosis | Dysmenorrhea | Pelvic Pain | Dyspareunia

Hong Kong, United States, Canada, Australia, United Kingdom, South Africa, Belgium

Clinical Trials on Pelvic Malignancy in South Africa

Sponsors and Collaborators

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CROs in Kyrgyzstan

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