Clinical Trials on Perioperative Hemorrhage in Czechia

Total 231 results

Charles University, Czech Republic
Ministry of Health, Czech Republic

Completed

Perioperative Ischemia Versus Perioperative Bleeding During Non-cardiac Surgery in Cardiac Patients (PRAGUE-14)

Perioperative Period | Surgical Procedure, Non-cardiac | Cardiovascular Disease Patients

Czechia
University Hospital Hradec Kralove

Recruiting

Impact of Nimodipine on Sublingual Microcirculation in Patients With Hemorrhage - a Prospective Monocentric Observational Study

Subarachnoid Hemorrhage

Czechia
Charles University, Czech Republic
Military University Hospital, Prague

Not yet recruiting

A Comparative Analysis of Prognostic Factors for Functional Outcomes in Patients With Acute Subdural Hematoma

Acquired Brain Injury | Acute Subdural Hematoma

Czechia
Masaryk University
Brno University Hospital

Recruiting

Incidence of Trauma Induced Coagulopathy in Patients With Prehospital Administration of Fibrinogen (TICAF)

Hemorrhage | Trauma | Coagulopathy

Czechia
Brno University Hospital

Completed

Perioperative Management of Temperature in Children and Influence of Hypothermia on Blood Clotting in Children. (Peritemp)

Perioperative Hypothermia

Czechia
EnteraSense Limited

Completed

Detection of Upper Gastrointestinal (GI) Bleeding Using a Novel Bleeding Sensor Capsule -Healthy Volunteers Study

Upper Gastrointestinal Bleeding

Czechia
University Hospital Hradec Kralove

Withdrawn

Mild Hypothermia During Intracranial Aneurysm Clipping

Subarachnoid Hemorrhage, Aneurysmal

Czech Republic
University of Defence, Faculty of Military Health...
University Hospital Hradec Kralove

Recruiting

Blood Loss Quantification During Major Abdominal Surgery

Postoperative Complications | Blood Loss, Surgical | Blood Loss, Postoperative

Czechia
Brno University Hospital
Masaryk University

Active, not recruiting

Perioperative Analgesia in Neonates Who Underwent Primary Cleft Lip Repair Surgery

Perioperative Analgesia in Neonates

Czechia
EnteraSense Limited

Completed

Detection of Upper Gastrointestinal (GI) Bleeding Using a Novel Bleeding Sensor Capsule -A Pilot Study

Upper Gastrointestinal Bleeding

Czechia
Czech Technical University in Prague
Military University Hospital, Prague

Recruiting

Blood Loss Measurement Using Electrical Impedance Tomography

Blood Loss

Czechia
Ondrej Hrdy

Recruiting

Evaluation of Coagulation Status of Pregnant Women in the Peripartum Period Using the Device Clotpro®

Coagulation and Hemorrhagic Disorders

Czechia
General University Hospital, Prague

Recruiting

Treatment of Postsphincterotomy Bleeding With a Novel Self-assembling Peptide Hemostatic Gel. (ERCPURA)

Complication of Treatment | Biliary Obstruction

Czechia
Charles University, Czech Republic

Completed

Perioperative Versus Postoperative Glycemia Control in Cardiac Surgery Patients

Perioperative and Postoperative Hyperglycemia | Tight Glycemia Control

Czech Republic
Samson NeuroSciences

Unknown

Safety Study of Carotid Body Neurostimulation to Treat Cerebral Vasospasm

Aneurysmal Subarachnoid Hemorrhage | Cerebral Vasospasm

Germany, Czech Republic, Israel
University Hospital Hradec Kralove

Completed

Can the Prophylactic Administration of Tranexamic Acid Reduce Blood Loss After Robotic-assisted Radical Prostatectomy? (RARPEX)

Robotic-assisted Radical Prostatectomy

Czechia
AGC Biologics S.p.A.
Horizon 2020 - European Commission

Terminated

Study of CAR T-cell Therapy in Acute Myeloid Leukemia and Multiple Myeloma

Acute Myeloid Leukemia | Multiple Myeloma

Italy, Czechia
PlasFree Ltd.
KCRI

Completed

Clinical Investigation of Safety and Performance of a Medical Device (ClearPlasma) for the Treatment of Patients With Acute Upper Gastrointestinal Hemorrhage.

Acute Upper Gastrointestinal Bleeding | Acute Upper Gastrointestinal Hemorrhage

Czechia, Israel, Italy
Idorsia Pharmaceuticals Ltd.

Completed

Clinical Research Study With Clazosentan to Evaluate Its Effects on Preventing Complications Due to the Narrowing of the Blood Vessels (Vasospasm) in the Brain, Caused by Bleeding Onto the Surface of the Brain (REACT)

Aneurysmal Subarachnoid Hemorrhage

United States, Spain, Israel, Finland, Poland, Austria, Belgium, Canada, Czechia, Denmark, France, Germany, Hungary, Italy, Sweden
Edge Therapeutics Inc

Terminated

Study of EG-1962 Compared to Standard of Care Oral Nimodipine in Adults With Aneurysmal Subarachnoid Hemorrhage (NEWTON2)

Subarachnoid Hemorrhage, Aneurysmal

United States, Canada, Australia, Hong Kong, Israel, New Zealand, Singapore, Finland, Czechia, Austria, Germany
Idorsia Pharmaceuticals Ltd.

Completed

Clazosentan in Reducing Vasospasm-related Morbidity and All-cause Mortality in Adult Patients With Aneurysmal Subarachnoid Hemorrhage Treated by Surgical Clipping (CONSCIOUS-2)

Aneurysmal Subarachnoid Hemorrhage

United States, Spain, Denmark, Hong Kong, India, Norway, Canada, Switzerland, China, France, Australia, Serbia, Latvia, Sweden, Austria, Germany, Slovenia, Belgium, Croatia, Czechia, Finland, Italy, Korea, Republic of, New Zealand, Poland, Russian Federation and more
Idorsia Pharmaceuticals Ltd.

Terminated

Clazosentan in Aneurysmal Subarachnoid Hemorrhage (CONSCIOUS-3)

Aneurysmal Subarachnoid Hemorrhage

United States, Belgium, Taiwan, Canada, Hong Kong, Singapore, Germany, Netherlands, India, Czechia, Switzerland, France, Australia, Spain, Denmark, Finland, Argentina, Brazil, Sweden, Austria, Chile, Hungary, Israel, Italy, Mexico, Norway, ... and more
Alexion Pharmaceuticals, Inc.

Completed

Trial of Andexanet Alfa in ICrH Patients Receiving an Oral FXa Inhibitor

Acute Intracranial Hemorrhage

Canada, Denmark, Italy, Netherlands, Spain, United States, Belgium, Switzerland, Germany, Hungary, Russian Federation, Czechia, France, United Kingdom, Israel, Austria, Norway, Latvia, Finland, Poland, Sweden, Portugal, Greece, Lithuania
Edge Therapeutics Inc

Completed

Safety and Tolerability Study of EG-1962 in Aneurysmal Subarachnoid Hemorrhage (NEWTON)

Ruptured Cerebral Aneurysm | Ruptured Berry Aneurysm

United States, Canada, Czechia, Finland
Masaryk University
Brno University Hospital

Completed

Comparison of Viscoelastic Measurement by ROTEM® Delta and ClotPro® in Trauma Patients. (ROTCLOT)

Coagulation Disorder | Polytrauma

Czechia
University Hospital, Motol

Terminated

Point-of-care Management of Coagulopathy in Lung Transplantation

Lung Transplantation

Czechia
Baxalta now part of Shire

Completed

Efficacy and Safety Study of a 10% Triple Virally Reduced Intravenous Immune Globulin Solution in Adult Subjects With Chronic Idiopathic Thrombocytopenic Purpura

Immune Thrombocytopenic Purpura (ITP)

Poland, Hungary, Germany, Czechia
Population Health Research Institute

Recruiting

EdoxabaN foR IntraCranial Hemorrhage Survivors With Atrial Fibrillation (ENRICH-AF) (ENRICH-AF)

Atrial Fibrillation | Intracranial Hemorrhages

Spain, Germany, United States, Belgium, United Kingdom, Switzerland, Egypt, Canada, Austria, China, Czechia, India, Nepal, Portugal, Argentina
University Hospital, Motol

Completed

ROTEM Assessment of Modern Crystalloid, Hydroxyethyl Starch and Gelatin Effect on Coagulation

Coagulopathy

Czechia
Zdravotnicka Zachranna Sluzba Kralovehradeckeho...
University Hospital Hradec Kralove

Unknown

Rapid Administration of Blood by HEMS in Trauma (RABBIT)

Wounds and Injuries | Trauma | Acute Coagulopathy

Czechia
Brno University Hospital

Recruiting

Effect of Prophylactic Fibrinogen Concentrate In Scoliosis Surgery (EFISS)

Bleeding | Spine Deformity | Coagulopathy, Consumption | Fibrinogen

Czechia
Biotest
Syneos Health

Completed

This Clinical Study is to Test Efficacy and Safety of BT595 in Chronic Primary Immune Thrombocytopenia (ITP)

Immune Thrombocytopenia

Bulgaria, Czechia, Germany, Hungary, Serbia, Spain
Oncopeptides AB

Withdrawn

A Study of OPD5 Followed by Autologous Stem Cell Transplant for Patients With Relapsed Refractory Multiple Myeloma (COAST)

Multiple Myeloma | Relapse Multiple Myeloma

Czechia
Medical University Innsbruck

Completed

Fibrinogen Concentrate (FGTW) in Trauma Patients, Presumed to Bleed (FI in TIC)

Trauma | Massive Hemorrhage

Austria, Czech Republic, Germany
Bioverativ, a Sanofi company

Completed

A Phase 2a Study Evaluating BIVV020 in Adults With Persistent/Chronic Immune Thrombocytopenia (ITP)

Immune Thrombocytopenia (ITP)

Germany, United States, Czechia, Netherlands, Spain, United Kingdom
University College Cork
Institut National de la Santé Et de la Recherche Médicale, France; KU Leuven; University of Alberta and other collaborators

Terminated

Management of Hypotension In the Preterm Infant (HIP)

Hypotension | Low Blood Pressure | Intraventricular Hemorrhage of Prematurity

Canada, Ireland, Belgium, Czechia, United Kingdom
European Myeloma Network
EMN Research Italy

Active, not recruiting

Daratumumab-bortezomib-dexamethasone (Dara-VCd) vs Bortezomib-Thalidomide-Dexamethasone (VTd), Then Maintenance With Ixazomib (IXA) or IXA-Dara

Multiple Myeloma

Czechia, Greece, Italy
Eisai Inc.

Completed

Efficacy and Safety of Oral E5501 Plus Standard of Care for the Treatment of Thrombocytopenia in Adults With Chronic Immune Thrombocytopenia (Amendment 02)

Immune Thrombocytopenia | Chronic Thrombocytopenia

Poland, Ukraine, Belgium, Bulgaria, South Africa, Netherlands, New Zealand, Singapore, Australia, Slovakia, Czechia
Population Health Research Institute

Terminated

DEPOSITION - Decreasing Postoperative Blood Loss by Topical vs. Intravenous Tranexamic Acid in Open Cardiac Surgery (DEPOSITION)

Bleeding | Seizures | Surgical Blood Loss

New Zealand, Canada, China, Malaysia, Czechia, Russian Federation
argenx
Quintiles, Inc.

Completed

A Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of ARGX-113 in Patients With ITP

Primary Immune Thrombocytopenia

Austria, Belgium, France, Germany, Spain, Czechia, Hungary, Poland, Ukraine, United Kingdom
UCB Biopharma SRL
Parexel

Completed

Study to Evaluate Safety, Tolerability and Efficacy of UCB7665 in Subjects With Primary Immune Thrombocytopenia

Thrombocytopenia

Australia, Bulgaria, Czechia, Georgia, Germany, Italy, Moldova, Republic of, Poland, Romania, Spain, United Kingdom
Hoffmann-La Roche

Completed

A Study of Mircera in Anemic Patients With Multiple Myeloma

Anemia

Poland, Czechia
Baxalta now part of Shire

Completed

Pharmacokinetics, Efficacy and Safety Study of IMMUNATE SD (Human Plasma-Derived Coagulation Factor VIII Concentrate) in Hemophilia A Patients

Hemophilia A

Czechia, Bulgaria, Hungary, Poland
Novo Nordisk A/S

Terminated

Evaluation of Recombinant Factor VIIa in Patients With Severe Bleeding (CONTROL)

Trauma | Acquired Bleeding Disorder

Spain, Hong Kong, Germany, France, United Kingdom, Brazil, Italy, Hungary, Netherlands, United States, Switzerland, Czech Republic, Greece, South Africa
Rigel Pharmaceuticals

Completed

A Efficacy and Safety Study of Fostamatinib in the Treatment of Persistent/Chronic Immune Thrombocytopenic Purpura (ITP) (FIT)

Immune Thrombocytopenic Purpura

Spain, Norway, Poland, Czechia, Germany, United States, Austria, Bulgaria, Romania
Bayer

Completed

MiCo - Mirena or Conventional Medical Treatment for Menorrhagia

Idiopathic Menorrhagia

Croatia, South Africa, Colombia, Czech Republic, Jordan, Lebanon, Macedonia, The Former Yugoslav Republic of, Moldova, Republic of, Romania, Ukraine, Venezuela, Bosnia and Herzegovina, Syrian Arab Republic, Albania
Novartis Pharmaceuticals

Recruiting

A Study of Ianalumab (VAY736) in Patients With Primary Immune Thrombocytopenia (ITP) Previously Treated With at Least Two Lines of Therapies

Primary Immune Thrombocytopenia (ITP)

Spain, Italy, France, Germany, China, Korea, Republic of, Czechia, Turkey, Malaysia, United States, Argentina, Australia, United Kingdom, Poland
Baxter Healthcare Corporation

Completed

Effectiveness and Safety of CELSTAT for Hemostasis in Intraoperative Tissue Bleeding (CELSTAT)

Bleeding Active

United States, Czechia, Germany, Poland
Swedish Orphan Biovitrum

Active, not recruiting

An Observational, Multicenter Study to Evaluate the Use and Effectiveness of Doptelet® in Patients With ITP (ADOPT)

Immune Thrombocytopenia | ITP

Croatia, Czechia, Germany, Italy, Netherlands, Norway, Spain, Switzerland, United Kingdom
Pfizer

Recruiting

Safety and Efficacy Study of PF-06835375 in Primary Immune Thrombocytopenia

Primary Immune Thrombocytopenia

United States, Australia, Canada, Czechia, Poland, Hungary, United Kingdom

Clinical Trials on Perioperative Hemorrhage in Czechia

Sponsors and Collaborators

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CROs in Bosnia & Herzegovina

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