Clinical Trials on Perioperative Complication

Total 27937 results

HRYZ Biotech Co.

Recruiting

HRYZ-T101 TCR-T Cell for HPV-18 Positive Advanced Solid Tumor

Cervical Cancer | Head and Neck Squamous Cell Carcinoma | Oropharyngeal Cancer | Anal Carcinoma | Vagina Tumor | Carcinoma of Penis | Carcinoma of Vulva

China
Ospedale San Raffaele

Recruiting

Tirzepatide Monotherapy in Patients With Wolfram Syndrome Type 1

Wolfram Syndrome

Italy
Emory University
National Cancer Institute (NCI)

Recruiting

Immune Checkpoint Inhibitors With or Without Propranolol Hydrochloride In Patients With Urothelial Carcinoma

Metastatic Bladder Urothelial Carcinoma | Metastatic Renal Pelvis Urothelial Carcinoma | Metastatic Ureter Urothelial Carcinoma | Metastatic Urethral Urothelial Carcinoma | Metastatic Urothelial Carcinoma | Stage IV Bladder Cancer AJCC v8 | Stage IV Renal Pelvis Cancer AJCC v8 | Stage IV Ureter Cancer... and other conditions

United States
National Cancer Institute (NCI)

Recruiting

A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon Cancers

Cervical Cancer | Vulvar Cancer | Colon Cancer | Anal Cancer | Vaginal Cancer | Oropharyngeal Cancer | Penile Cancer | HPV | Human Papillomavirus | Neck Cancer

United States
Washington University School of Medicine

Withdrawn

GI Organ Tracking Via Balloon Applicators

Kidney Cancer | Stomach Cancer | Esophageal Cancer | Small Intestine Cancer | Lung Cancer | Rectal Cancer | Colon Cancer | Pancreas Cancer | Liver Cancer | Larynx Cancer | Digestive Organs--Cancer | Intrathoracic--Cancer | Respiratory Organs--Cancer

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Hyperthermic Intraperitoneal Chemotherapy Trial Comparing Quality of Life in Patients With Stage IIIC-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Stage IIIC Fallopian Tube Cancer | Stage IIIC Ovarian Cancer | Stage IIIC Primary Peritoneal Cancer | Stage IV Fallopian Tube Cancer | Stage IV Ovarian Cancer | Stage IV Primary Peritoneal Cancer

United States
University of Calgary
University of Alberta

Completed

ENCOMPASS: Expansion Study A, RCT (ENCOMPASS)

Hypertension | Diabetes Mellitus, Type 2 | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Asthma | Ischemic Heart Disease | Congestive Heart Failure

Canada
Scynexis, Inc.

Completed

Study to Evaluate the Efficacy and Safety of Ibrexafungerp in Patients With Fungal Diseases That Are Refractory to or Intolerant of Standard Antifungal Treatment (FURI)

Coccidioidomycosis | Invasive Pulmonary Aspergillosis | Allergic Bronchopulmonary Aspergillosis | Histoplasmosis | Chronic Pulmonary Aspergillosis | Blastomycosis | Invasive Candidiasis | Recurrent Vulvovaginal Candidiasis | Mucocutaneous Candidiasis | Other Emerging Fungi

United States, Spain, United Kingdom, Austria, Pakistan, South Africa, Germany, Netherlands
Poseida Therapeutics, Inc.

Active, not recruiting

P-PSMA-101 CAR-T Cells in the Treatment of Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC) and Advanced Salivary Gland Cancers (SGC)

Neoplasms | Neoplasms by Histologic Type | Urogenital Neoplasms | Neoplasms by Site | Genital Neoplasms, Male | Prostatic Neoplasms | Adenoid Cystic Carcinoma | Mucoepidermoid Carcinoma | Prostate Cancer | Prostatic Neoplasms, Castration-Resistant | Metastatic Castration-resistant Prostate Cancer | Neoplasms... and other conditions

United States
Pfizer

Active, not recruiting

Study of PF-06940434 in Patients With Advanced or Metastatic Solid Tumors.

Renal Cell Carcinoma | Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Squamous Cell Carcinoma of the Head and Neck | Bile Duct Cancer | Endometrial Cancer | Urothelial Cancer | Lung Squamous Cell Carcinoma | Melanoma Cancer

United States, Taiwan, Korea, Republic of, Australia, Slovakia
Cornell University
Laidlaw Foundation; Epperson Fund; Beck Fellowship; Dan Cane Fund

Completed

Effect of 'Cramp Bites' on Period Cramps in Women Aged 18-25 (NUTRITION; GYN)

Polycystic Ovary Syndrome | Ovarian Cysts | PCOS | Dysmenorrhea | Menstrual Pain | Premenstrual Dysphoric Disorder | Premenstrual Syndrome | Period Pain | Menstrual Problem | PMS | Menstrual Discomfort | Dysmenorrhea Primary | Cramps | Menstrual Cycle Abnormal | PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries | Period... and other conditions

United States
Washington University School of Medicine

Enrolling by invitation

I-Tracking Neurodegeneration in Early Wolfram Syndrome (I-TRACK)

Wolfram Syndrome

United States
National Cancer Institute (NCI)

Completed

Liposomal Doxorubicin in Treating Children With Refractory Solid Tumors

Bone Cancer | Brain Tumor | Kidney Tumor | Childhood Soft Tissue Sarcoma | Childhood Liver Cancer

United States
Croatian Society for Organ Support
Clinical Hospital Centre Zagreb

Enrolling by invitation

Registry for Hemoperfusion of Covid-19 ICU Patients (HERICC)

Systemic Inflammatory Response Syndrome | Critical Illness | Multi Organ Failure | COVID-19 Acute Respiratory Distress Syndrome | Viral Disease | AKI - Acute Kidney Injury

Croatia
Reata, a wholly owned subsidiary of Biogen

Completed

A Phase 2 Trial of the Safety and Efficacy of Bardoxolone Methyl in Patients With Rare Chronic Kidney Diseases - PHOENIX (PHOENIX)

Focal Segmental Glomerulosclerosis | IgA Nephropathy | Autosomal Dominant Polycystic Kidney | CKD Associated With Type 1 Diabetes

United States
Peloton Therapeutics, Inc., a subsidiary of Merck...
National Institutes of Health (NIH)

Completed

PT2385 for the Treatment of Von Hippel-Lindau Disease-Associated Clear Cell Renal Cell Carcinoma

Clear Cell Renal Cell Carcinoma | Von Hippel-Lindau Disease | Clear Cell RCC | ccRCC | VHL Gene Mutation | VHL Syndrome | VHL Gene Inactivation | VHL | Von Hippel | Von Hippel's Disease | Von Hippel-Lindau Syndrome, Modifiers of

United States
Mundipharma Research Limited

Completed

Study of the Safety, Pharmacokinetics and Efficacy of EDO-S101, in Patients With Advanced Solid Tumors

Soft Tissue Sarcoma | Ovarian Cancer | Endometrial Cancer | Small-cell Lung Cancer | Triple-negative Breast Cancer

United States, Canada
Incyte Corporation

Completed

A Study of INCMGA00012 in Participants With Selected Solid Tumors (POD1UM-203)

Metastatic Melanoma | Unresectable Melanoma | Metastatic Urothelial Cancer | Metastatic Non-small Cell Lung Cancer | Locally Advanced Renal Cell Carcinoma | Locally Advanced Urothelial Cancer | Metastatic Clear-Cell Renal Cell Carcinoma

France, Spain, United States, Italy, Austria, Romania, Poland, Hungary
Tempest Therapeutics

Completed

TPST-1120 as Monotherapy and in Combination With Nivolumab in Subjects With Advanced Cancers

Sarcoma | Renal Cell Carcinoma | Hepatocellular Carcinoma | Colorectal Cancer | Pancreatic Cancer | Squamous Cell Carcinoma of Head and Neck | Cholangiocarcinoma | Non-small Cell Lung Cancer | Urothelial Carcinoma | GastroEsophageal Cancer | Triple-Negative Breast Cancer | Metastatic Castration Resistant Prostate...

United States
Abramson Cancer Center at Penn Medicine

Enrolling by invitation

Sequential EHR Based Interventions to Increase Genetic Testing for Breast and Ovarian Cancer Predisposition

Ovarian Cancer | Genetic Predisposition to Disease | Breast Cancer Female | Hereditary Diseases | Gene Mutation-Related Cancer | Hereditary Breast and Ovarian Cancer | Hereditary Cancer Syndrome

United States
Altesa Biosciences, Inc.
Virtus Respiratory Research

Recruiting

RCT of Vapendavir in Patients With COPD and Human Rhinovirus/Enterovirus Upper Respiratory Infection

Infections | Virus Diseases | Respiratory Tract Infections | Respiratory Tract Diseases | Lung Diseases | Pulmonary Disease, Chronic Obstructive | Enterovirus Infections | Copd | Pulmonary Disease | Respiratory Disease | Respiratory Complication | Upper Respiratory Tract Infections | Respiratory Viral Infection | ... and other conditions

United Kingdom
Zhejiang University

Not yet recruiting

A Clinical Study of Anti-CD70 UCAR-T in Relapsed or Refractory Solid Tumors

Renal Cell Carcinoma | Nasopharyngeal Carcinoma | Ovarian Cancer | Cervix Cancer | Advanced Solid Tumor | Head and Neck Squamous Cell Carcinoma | Metastatic Tumor
ImmunoGen, Inc.

Not yet recruiting

A Study of Ocular Toxicity Evaluation and Mitigation During Treatment With Mirvetuximab Soravtansine in Participants With Recurrent Ovarian Cancer With High Folate Receptor-Alpha Expression

Recurrent Ovarian Cancer | Folate Receptor-Alpha Positive

United States, Spain, Australia, Belgium, Canada, France, Ireland, Italy
Hospital Universitari Vall d'Hebron Research Institute
Erasme University Hospital; Cyprus Institute of Neurology and Genetics; EuroBloodNet...

Recruiting

RADeep Multicenter European Epidemiological Platform for Patients Diagnosed With Rare Anemia Disorders (RADs) (RADeep)

Iron Metabolism Disorders | Sickle Cell Disease | Thalassemia | Hemolytic; Anemia, Hereditary, Due to Enzyme Disorder | Anemia Due to Membrane Defect | CDA | Sideroblastic Anemia | Constitutional Aplastic Anemia | Hereditary Anemia

Spain
Third Military Medical University

Not yet recruiting

Spatial Proteomics Profiles of Aldosterone-producing Adenoma and Unilateral Hyperplasia

Primary Aldosteronism Due to Aldosterone Producing Adenoma | Primary Aldosteronism Due to Adrenal Hyperplasia (Bilateral)

China
Boston Children's Hospital

Recruiting

Delineating the Molecular Spectrum and the Clinical, Imaging and Neuronal Phenotype of Chopra-Amiel-Gordon Syndrome

Genetic Disease | Chopra-Amiel-Gordon Syndrome | CAGS | ANKRD17

United States
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Recruiting

Interleukin-15 Armored Glypican 3-specific Chimeric Antigen Receptor Expressed in Autologous T Cells for Solid Tumors

Solid Tumor | Liposarcoma | Rhabdomyosarcoma | Wilms Tumor | Malignant Rhabdoid Tumor | Yolk Sac Tumor | Liver Cell Carcinoma | Embryonal Sarcoma of the Liver

United States
Boston University
National Institute on Minority Health and Health Disparities (NIMHD); University... and other collaborators

Recruiting

Scalable Communication Modalities for Returning Genetic Research Results (BWHS RoR)

Lynch Syndrome | Hereditary Breast and Ovarian Cancer

United States
Jason J. Luke, MD

Recruiting

Evaluating Length of Treatment With PD-1/PD-L1 Inhibitor in Advanced Solid Tumors

Melanoma | Cervical Cancer | Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | NSCLC | Advanced Solid Tumors | Cholangiocarcinoma | Bladder Cancer | Renal Cancer | Anal Cancer | Merkel Cell Carcinoma | HNSCC

United States
Apollomics Inc.

Recruiting

APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors (SPARTA)

Gastric Cancer | Pancreatic Cancer | NSCLC | Lung Cancer | Brain Tumor | Glioblastoma Multiforme | Advanced Cancer | Colon Cancer | Solid Tumors | Thyroid Cancer | Renal Cancer | Gastroesophageal Junction Adenocarcinoma | EGFR Gene Mutation | MET Amplification | HGF | MET Alteration | MET Fusion | Exon 14 Skipping

United States, Spain, France, United Kingdom, Taiwan, Australia, Finland, Italy, Singapore, Hungary, Canada, Puerto Rico, Russian Federation
National Human Genome Research Institute (NHGRI)

Completed

Study of People With Generalized Arterial Calcification of Infancy (GACI) or Autosomal Recessive Hypophosphatemic Rickets Type 2 (ARHR2)

Generalized Arterial Calcification of Infancy | Autosomal Recessive Hypophosphatemic Rickets Type2

United States
University of Calgary
University of Alberta

Completed

ENCOMPASS: Expansion Study C

Hypertension | Diabetes Mellitus, Type 2 | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Asthma | Ischemic Heart Disease | Congestive Heart Failure

Canada
University of Calgary
Alberta Innovates Health Solutions; Canadian Diabetes Association

Completed

Enhancing Community Health Through Patient Navigation, Advocacy and Social Support (ENCOMPASS)

Hypertension | Diabetes Mellitus, Type 2 | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Asthma | Ischemic Heart Disease | Congestive Heart Failure

Canada
Rigshospitalet, Denmark
University College, London

Enrolling by invitation

EuroSIDA - Clinical and Virological Outcome of European Patients Infected With HIV (EuroSIDA)

End Stage Liver Disease | Cardiovascular Diseases | Fractures, Bone | Diabetes Mellitus | Renal Insufficiency | Hepatitis B | Hepatitis C | Kidney Failure, Chronic | Proteinuria | HIV | Coinfection | Acidosis, Lactic | AIDS

Spain, Switzerland, Germany, United Kingdom, Austria, Sweden, Finland, Israel, Denmark, France, Italy, Iceland, Belgium, Slovakia, Norway, Lithuania, Portugal, Poland, Croatia, Czechia, Greece, Hungary, Luxembourg, Argentina, Belarus, Bosnia... and more
Pfizer

Completed

Study to Test the Safety and Tolerability of PF-07257876 in Participants With Selected Advanced Tumors.

Ovarian Cancer | Non-Small Cell Lung Cancer | Squamous Cell Carcinoma of the Head and Neck

United States, Spain
Peloton Therapeutics, Inc., a subsidiary of Merck...

Active, not recruiting

A Phase 2 Study of Belzutifan (PT2977, MK-6482) for the Treatment of Von Hippel Lindau (VHL) Disease-Associated Renal Cell Carcinoma (RCC) (MK-6482-004)

VHL - Von Hippel-Lindau Syndrome | VHL Gene Mutation | VHL Syndrome | VHL Gene Inactivation | VHL-Associated Renal Cell Carcinoma | VHL-Associated Clear Cell Renal Cell Carcinoma

United States, Denmark, United Kingdom, France
Seagen Inc.

Terminated

A Study of SGN-ALPV in Advanced Solid Tumors

Uterine Cervical Neoplasms | Stomach Neoplasms | Testicular Neoplasms | Carcinoma, Non-Small-Cell Lung | Ovarian Neoplasms | Endometrial Neoplasms | Gastroesophageal Junction Carcinoma

United States, Canada, Spain, Sweden, United Kingdom
University Health Network, Toronto
Merck Sharp & Dohme LLC

Active, not recruiting

Study of the Effects of Pembrolizumab in Patients With Advanced Solid Tumors (INSPIRE)

Advanced Solid Tumors | Triple Negative Breast Cancer | Epithelial Ovarian Cancer | Malignant Melanoma | Squamous Cell Cancer of Head and Neck

Canada
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

CBM588 in Combination With Nivolumab and Cabozantinib for the Treatment of Advanced or Metastatic Kidney Cancer

Metastatic Renal Cell Carcinoma | Metastatic Clear Cell Renal Cell Carcinoma | Advanced Clear Cell Renal Cell Carcinoma | Stage III Renal Cell Cancer AJCC v8 | Stage IV Renal Cell Cancer AJCC v8 | Metastatic Sarcomatoid Renal Cell Carcinoma | Advanced Renal Cell Carcinoma | Unresectable Renal Cell... and other conditions

United States
Children's National Research Institute
Bristol-Myers Squibb

Active, not recruiting

Neoadjuvant Dual Checkpoint Inhibition and Cryoablation in Relapsed/Refractory Pediatric Solid Tumors

Melanoma | Hepatocellular Carcinoma | Osteosarcoma | Ewing Sarcoma | Neuroblastoma | Rhabdomyosarcoma | Wilms Tumor | Hepatoblastoma | Relapsed Pediatric Solid Tumor | Refractory Pediatric Solid Tumor

United States
University of Birmingham

Active, not recruiting

Efficacy and Safety Trial of Sodium Valproate, in Paediatric and Adult Patients With Wolfram Syndrome

Wolfram Syndrome

France, United Kingdom, Poland, Spain
Celldex Therapeutics

Completed

A Study of the PD-L1xCD27 Bispecific Antibody CDX-527 in Patients With Advanced Malignancies

Renal Cell Carcinoma | Breast Cancer | Head and Neck Cancer | Gastric Cancer | Esophageal Cancer | Ovarian Cancer | Fallopian Tube Cancer | Cholangiocarcinoma | Non-small Cell Lung Cancer | Primary Peritoneal Carcinoma | Hepatic Cancer | Bladder Urothelial Carcinoma | Other Solid Tumors | MSI-H Colorectal Cancer

United States
7 Hills Pharma, LLC

Recruiting

A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

Melanoma | Kidney Cancer | Renal Cell Carcinoma | Hepatocellular Carcinoma | Colorectal Cancer | NSCLC | Non Small Cell Lung Cancer | Skin Cancer | Metastasis | Advanced Solid Tumor | Advanced Cancer | Renal Cell Cancer | Hepatocellular Cancer | Mismatch Repair Deficiency | Pleural Mesothelioma | MSI-High | Anaplastic Lymphoma... and other conditions

United States
Rigshospitalet, Denmark

Recruiting

Polyneuropathy, Impairments and Physical Activity - The PolyImPAct Study (PolyImPAct)

Polyneuropathies | Diabetic Polyneuropathy | Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) | POEMS Syndrome | Multifocal Motor Neuropathy | Charcot-Marie-Tooth | hATTR Amyloidosis | Vasculitic Neuropathy | Idiopathic Neuropathy

Denmark
Molecular Templates, Inc.

Recruiting

Study of MT-8421 as Monotherapy and in Combination With Nivolumab in Patients With Selected Advanced Solid Cancer Types

Melanoma | Renal Cell Carcinoma | Cervical Cancer | Hepatocellular Carcinoma | Non Small Cell Lung Cancer | Mesothelioma | Squamous Cell Carcinoma of Head and Neck | Esophageal Squamous Cell Carcinoma | Urothelial Carcinoma | Microsatellite Instability High | Mismatch Repair Deficiency

United States
Poseida Therapeutics, Inc.

Recruiting

P-MUC1C-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Advanced or Metastatic Solid Tumors

Renal Cell Carcinoma | Breast Cancer | Nasopharyngeal Cancer | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma

United States
Shanghai Escugen Biotechnology Co., Ltd

Recruiting

Study of ESG401 in Adults With Solid Tumors

Neoplasms, Lung | Neoplasms, Breast | Neoplasms,Colorectal | Neoplasm of Stomach | Neoplasms, Bladder | Neoplasms,Ovarian

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

DS3201 and Ipilimumab for the Treatment of Metastatic Prostate, Urothelial and Renal Cell Cancers

Metastatic Clear Cell Renal Cell Carcinoma | Castration-Resistant Prostate Carcinoma | Metastatic Prostate Carcinoma | Stage IV Prostate Cancer AJCC v8 | Stage IV Renal Cell Cancer AJCC v8 | Metastatic Malignant Solid Neoplasm | Metastatic Urothelial Carcinoma | Stage IVA Prostate Cancer AJCC v8 | Stage... and other conditions

United States
BioEclipse Therapeutics

Recruiting

Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid Malignancies

Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Osteosarcoma | Triple Negative Breast Cancer | Epithelial Ovarian Cancer | Non-small Cell Lung Cancer | Solid Tumor, Adult | Malignant Melanoma

United States
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Recruiting

Olaparib in Treating Patients With Metastatic Biliary Tract Cancer With Aberrant DNA Repair Gene Mutations

Bile Duct Adenocarcinoma | Fanconi Anemia Complementation Group Gene Mutation | Metastatic Bile Duct Carcinoma | PTEN Gene Deletion

United States

Clinical Trials on Perioperative Complication

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