Clinical Trials on Peripheral Vascular Disease in South Africa

Total 18800 results

Hemostemix

Completed

ACP-01 in Patients With Critical Limb Ischemia

Critical Limb Ischemia

United States, Canada
Pfizer

Completed

An Open-label Study of APX001 for Treatment of Patients With Candidemia/Invasive Candidiasis Caused by Candida Auris (APEX)

Candidemia | Candida Infection | Invasive Candidiases

South Africa
GlaxoSmithKline

Completed

Restless Legs Patient Study On Absorption, Distribution, Metabolism And Excretion Of Ropinirole And The Effect Of Food

Restless Legs Syndrome

Germany, South Africa
GlaxoSmithKline

Completed

Bioequivalence Study Between SKF101804 Cefixime 200 Milligram (mg)/5 Milliliter (mL) Suspension Versus Cefixime 200 mg/5 mL Suspension Reference Product in Healthy Adult Subjects Under Fasting Conditions

Infections, Bacterial

South Africa
University of Cape Town
King's College London; University of KwaZulu

Completed

Collaborative Care for the Detection and Management of Depression Among Adults Receiving Antiretroviral Therapy in South Africa (COBALT)

Depression | HIV/AIDS | Chronic Diseases of Lifestyle

South Africa
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Evaluation of the XtremeCT Device for the Assessment of Bone (XtremeCT)

Peripheral Bone Density

United Kingdom
GlaxoSmithKline
Aeras

Completed

Safety and Immunogenicity of a Candidate Tuberculosis (TB) Vaccine in Healthy HIV Negative Adolescents

Tuberculosis

South Africa
Massachusetts General Hospital
National Institute of Allergy and Infectious Diseases (NIAID); AIDS Healthcare...

Completed

Test and Treat TB: A Proof of Concept Trial in South Africa (Siyasiza)

Tuberculosis

South Africa
Centre for the AIDS Programme of Research in South...
Institute for Healthcare Improvement; BroadReach Health Care

Completed

Scaling up TB and HIV Treatment Integration (SUTHI)

HIV | Tuberculosis

South Africa
Aeras
Crucell Holland BV

Completed

Safety and Immunogenicity of AERAS-402 in HIV-infected, Bacillus Calmette-Guerin (BCG)-Vaccinated Adults

HIV Infections | Tuberculosis

South Africa
Aeras
Crucell Holland BV

Completed

A Study to Evaluate the Safety of AERAS-402 in Adults Recently Treated for Pulmonary TB (C-010-402)

Tuberculosis

South Africa
Centre for the AIDS Programme of Research in South...

Completed

A Study to Compare Three Existing Starting Points of Anti-Retroviral Therapy (ART) Initiation in HIV/Tuberculosis (TB) Co-infected Patients (SAPIT)

HIV Infections | Tuberculosis

South Africa
University of Stellenbosch

Unknown

The Utility of Radiotherapy in the Management of Haemoptysis Secondary to Aspergillomata and Structural Lung Diseases

Haemoptysis

South Africa
Centre for the AIDS Programme of Research in South...

Completed

Improving Retreatment Success (IMPRESS) (IMPRESS)

Recurrent Tuberculosis

South Africa
Biofabri, S.L
University of Stellenbosch; University of Cape Town; TuBerculosis Vaccine Initiative and other collaborators

Recruiting

Efficacy, Safety and Immunogenicity Evaluation of MTBVAC in Newborns in Sub-Saharan Africa (MTBVACN3)

Tuberculosis

South Africa
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

Drug-drug Interaction Study With MDV3100 and a Cocktail of Substrates

Castration Resistant Prostate Cancer (CRPC) | Pharmacokinetics of MDV3100

South Africa
University of KwaZulu
Centre for the AIDS Programme of Research in South Africa

Recruiting

Pharmacokinetics of Twice or Once Daily DTG (50mg) in Children With HIV and TB (ORCHID)

Tuberculosis | Hiv

South Africa
University of Illinois at Chicago
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

A Comprehensive HIV Prevention Package for South African Adolescent Girls and Young Women: IMARA SA (IMARA-SA pilot)

Hiv | Sexually Transmitted Infection

South Africa
RTI International
University of Cape Town

Completed

Treating South African Pregnant Women for Methamphetamine

HIV | Drug Addiction

South Africa
Columbia University
Centre for the AIDS Programme of Research in South Africa

Not yet recruiting

An Adaptive Randomized Controlled Trial (ADAP-TIV)

HIV Infections | Multi Drug Resistant Tuberculosis

South Africa
AnGes USA, Inc.

Recruiting

Study of AMG0001 to Improve Ulcer Healing and Perfusion in Subjects With Peripheral Ischemic Ulcers

Peripheral Artery Disease | Chronic Limb Threatening Ischemia | Ischaemic Ulcer of Lower Leg Due to Atherosclerotic Disease | Ischemic Ulcer of Foot

United States
University of Stellenbosch
University of Rochester; Fogarty International Center of the National Institute...

Recruiting

A Pilot Study of Metformin to Reduce Cerebrovascular Dysfunction in Participants With HIV and Metabolic Syndrome. (SMART)

Metabolic Syndrome | HIV Seropositivity

South Africa
SIMR (Australia) Biotech Pty Ltd.

Completed

A Phase 1b Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of SR419

Peripheral Neuropathic Pain

Australia
Brown University
Rhode Island Hospital; University of Cape Town; Medical Research Council, South... and other collaborators

Active, not recruiting

Our Family Our Future: A Resilience-oriented Family Intervention to Prevent Adolescent HIV/STI Infection and Depression in South Africa

Depression | Sexually Transmitted Diseases | Human Immunodeficiency Virus

South Africa
Archivel Farma S.L.
Parexel

Completed

Clinical Trial to Investigate the Safety, Tolerability, and Immunogenicity of the Novel Antituberculous Vaccine RUTI® Following One Month of Isoniazid Treatment in Subjects With Latent Tuberculosis Infection

Tuberculosis | Latent Tuberculosis Infection

South Africa
University of Cape Town
London School of Hygiene and Tropical Medicine; Johns Hopkins University; Imperial... and other collaborators

Completed

Isoniazid Plus Antiretroviral Therapy to Prevent Tuberculosis in HIV-infected Persons (HAART-IPT)

HIV Infections | Tuberculosis | Latent Tuberculosis Infection

South Africa
University of Bern
University of Alabama at Birmingham; University of Southern California; Louisiana... and other collaborators

Active, not recruiting

Genital Tract Infections, the Vaginal Microbiome and Gestational Age at Birth Among Pregnant Women in South Africa

HIV Infections | Premature Birth | Microbial Colonization | Pregnancy; Infection | Bacterial Vaginosis | Trichomonas Vaginitis | Neisseria Gonorrheae Infection | Chlamydia Trachomatis Infection | Mycoplasma Genitalium Infection | Genital Mycoplasma Infection | Vaginal Candida | Sexually Transmitted Infections... and other conditions

South Africa
Novartis Pharmaceuticals

Completed

Dose Response of Valsartan on Sitting Systolic Blood Pressure in Children 6 Months - 5 Years of Age With High Blood Pressure

Hypertension

Sweden, Belgium, Hungary, India, Italy, Poland, Turkey, United States, Brazil, France, South Africa
Red Cross War Memorial Childrens Hospital

Completed

Accessible and Affordable Moisturizers for Atopic Eczema

Childhood Atopic Dermatitis

South Africa
Foundation for Professional Development (Pty) Ltd
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Recruiting

Clinical Study of STI Screening to Prevent Adverse Birth and New-born Outcomes

HIV/AIDS | Pregnancy | Cost-effectiveness | Antenatal Care | Chlamydia Trachomatis | Vaginal Microbiome | Birth Outcomes | Sexually Transmitted Infection | Neisseria Gonorrhoeae | Trichomonas Vaginalis

South Africa
GlaxoSmithKline

Completed

Parkinson's Disease Patient Study On Absorption, Distribution, Metabolism And Excretion Of Ropinirole

Parkinson Disease

Germany, South Africa
University of Cape Town
London School of Hygiene and Tropical Medicine

Completed

Pharmacokinetic Interaction Between the Antimalarial Combination Artemether/Lumefantrine and Combination Antiretroviral Therapy Including Lopinavir/Ritonavir in HIV-infected Adults (SEACAT 2_4_2)

HIV Infections | Malaria

South Africa
Henry M. Jackson Foundation for the Advancement...
Johns Hopkins University; Karolinska Institutet; University of Miami; Chulalongkorn... and other collaborators

Active, not recruiting

Safety and Effects of Using Prime-boost HIVIS DNA and MVA-CMDR Vaccine Regimens With or Without Toll-like Receptor 4 Agonist on HIV Reservoirs in Perinatally HIV Infected Children and Youth (HVRRICANE)

HIV Infections

South Africa
University of Pennsylvania
Bill and Melinda Gates Foundation; Desmond Tutu HIV Foundation

Completed

Effect of U=U Messaging on HIV in South Africa (U=U)

HIV/AIDS

South Africa
Johns Hopkins University
National Institute of Mental Health (NIMH); University of Witwatersrand, South...

Completed

Home Link: Post Hospital Care to Reduce HIV Mortality in South Africa (HomeLink)

HIV/AIDS

South Africa
University of Cape Town
Medtronic

Suspended

Left Cardiac Sympathetic Denervation for Cardiomyopathy Feasibility Pilot Study (LCSD)

Dilated Cardiomyopathy | Ischemic Cardiomyopathy | Non-ischemic Cardiomyopathy

South Africa
University of Cape Town

Completed

The Role of Melatonin in the Effective Attainment of Sleep Electroencephalograms (EEG) in Children

Epilepsy | Children | Sedation | Electroencephalogram

South Africa
University of Cape Town
Imperial College London; Institute of Tropical Medicine, Belgium; European and... and other collaborators

Completed

Preventing TB-IRIS in High-risk Patients: a Randomized Placebo-controlled Trial of Prednisone (Pred-ART)

HIV | Tuberculosis | Immune Reconstitution Inflammatory Syndrome

South Africa
University of Cape Town
Merck Sharp & Dohme LLC

Completed

Typing of Human Papilloma Virus (HPV) From Female Genital Warts

Genital Warts | Human Papilloma Virus

South Africa
AstraZeneca

Completed

Type III Dysbetalipoproteinemia

Hyperlipoproteinemia Type III

South Africa, Norway
University of Cape Town

Completed

Modified Endotracheal Balloon Dilator to Improve Patient Oxygenation and Allow Ventilation During Airway Procedures

Tracheal Stenosis

South Africa
University of Cape Town

Recruiting

Evaluating Acid Reflux After Oesophageal Stenting Using Anti-reflux Stents

Esophageal Cancer | Reflux, Gastroesophageal

South Africa
University of Cape Town

Unknown

Sub-project: Use of Small Implantable ECG Recorder in Pregnant Women With Arrhythmia (REVEAL)

Arrhythmias in Pregnancy

South Africa
Desmond Tutu HIV Foundation
Karolinska Institutet; University of North Carolina, Chapel Hill; ViiV Healthcare and other collaborators

Completed

Bidirectional, Upbeat Communication and Differentiated, Distanced Care for Young People (BUDDY)

HIV Infections | Covid19 | Health Care Utilization | Gender-based Violence

South Africa
Foundation for Innovative New Diagnostics, Switzerland

Completed

Evaluation of the Performance of Rapid Diagnostics for SARS-CoV-2 Self-testing in the Hands of Untrained (CV009)

COVID-19

South Africa, Uganda
University of Cape Town

Completed

VATS ( Video-Assisted Thoracoscopy) Compared to Reinsertion of a Thoracostomy Tube for Persistent Haemothorax

Empyema | Haemothorax

South Africa
TASK Applied Science

Completed

BCG Vaccination for Healthcare Workers in COVID-19 Pandemic

COVID-19 | Sars-CoV2

South Africa
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Nitazoxanide for the Treatment of Chronic Diarrhea in HIV Infected Children

HIV Infections | Cryptosporidiosis

South Africa, Thailand
University of Cape Town
Natal Bioproducts Institute

Completed

Intravenous Immunoglobulins as Effective Treatment in Sydenham's Chorea

Sydenham Chorea | Post Streptococcal Movement Disorder

South Africa
University of Cape Town
University of KwaZulu

Unknown

African Covid-19 Critical Care Outcomes Study

Severe Acute Respiratory Syndrome Coronavirus 2

South Africa

Clinical Trials on Peripheral Vascular Disease in South Africa

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