Clinical Trials on Peripheral Vascular Disease in South Africa

Total 18907 results

Medtronic BRC

Terminated

Model 20105 Lead Study

Sick Sinus Node Syndrome

South Africa, Netherlands, Canada, Singapore
Serum Institute of India Pvt. Ltd.
Bill and Melinda Gates Foundation

Not yet recruiting

Clinical Study to Evaluate SIIPL qHPV Vaccine (CERVAVAC®) in Women Living With HIV Aged 15-25 Years

Human Papillomavirus Infection

Kenya, Mozambique, South Africa
Eastern Virginia Medical School
Gilead Sciences; United States Agency for International Development (USAID); FHI... and other collaborators

Active, not recruiting

Project Engage: Oral PrEP Acceptability

Adherence, Medication | Acceptability of Health Care

South Africa, Zimbabwe
Massachusetts General Hospital
Harvard Medical School (HMS and HSDM); National Institute of Allergy and Infectious... and other collaborators

Completed

Population Effectiveness of Dolutegravir Implementation in Sub-Saharan Africa (DISCO)

HIV-1-infection

Uganda, South Africa
Medtronic BRC

Unknown

RESpiration deTection From Implanted Cardiac Devices in Subjects With Heart Failure (REST-HF) (REST-HF)

Heart Failure

Belgium, South Africa
University of Pretoria
University of Stellenbosch

Active, not recruiting

Effectiveness Study of Human Papilloma Virus (HPV) Vaccines to Prevent Recurrence of Genital Warts (TheraVACCS)

Genital Warts

South Africa
H. Lee Moffitt Cancer Center and Research Institute
Merck Sharp & Dohme LLC

Completed

Preparedness Study - HPV Vaccine

Sexual Transmission of Infection

United States, South Africa
FHI 360
University of Cape Town; City University of New York, School of Public Health

Completed

Comparison of Two Intrauterine Devices (IUDs) Among Cape Town HIV-positive Women

HIV

South Africa
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

High-Dose Isoniazid Among Adult Patients With Different Genetic Variants of INH-Resistant Tuberculosis (TB)

Tuberculosis

Haiti, South Africa
Barbara Ensoli, MD
Italian Ministry of Foreign Affairs - Dir. Gen. for Cooperation and Development

Completed

Study to Assess the Seroprevalence of Anti-Tat Antibodies in HIV-infected Patients (ISS OBS T-004)

HIV Infection

South Africa
University of Stellenbosch
University of Pittsburgh

Unknown

TB-IRIS NSAID Cox-2 Inhibitor Prevention Trial

Tuberculosis

South Africa
MedImmune LLC

Completed

A Study to Evaluate the Safety of MEDI2338 in Subjects With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

United Kingdom, South Africa
Boehringer Ingelheim

Completed

Trial to Evaluate Steady State Pharmacokinetic Parameters, Efficacy and Safety of Nevirapine in Antiretroviral Drug naïve Pediatric Patients

HIV Infections

South Africa
University of Stellenbosch

Completed

Probiotics in the Management of Necrotizing Enterocolitis in HIV-exposed Premature Infants

Necrotizing Enterocolitis

South Africa
MedImmune LLC
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Trial to Compare the Safety, Tolerability, and Efficacy of Influenza Virus Vaccine, (CAIV-T) With Inactivated, Influenza Vaccine, Trivalent, Types A & B, in Adults Aged 60 Years and Older Against Culture-confirmed Influenza (FluMist)

Influenza

South Africa
BioNTech SE

Recruiting

Safety and Immune Responses After Vaccination With Two Investigational RNA-based Vaccines Against Tuberculosis in BCG Vaccinated Volunteers

Tuberculosis

South Africa
The Aurum Institute NPC
Johns Hopkins University

Recruiting

Rifapentine and Isoniazid TB Preventive Therapy (3HP) for Children Taking Dolutegravir-based Antiretroviral Treatment (DOLPHIN KIDS) (DOLPHIN KIDS)

HIV | Tuberculosis

South Africa
University of Minnesota
National Institute of Allergy and Infectious Diseases (NIAID); Makerere University and other collaborators

Completed

Cryptococcal Optimal ART Timing Trial (COAT)

HIV Infections | AIDS | Cryptococcal Meningitis

Uganda, South Africa
Vanderbilt University Medical Center
Massachusetts General Hospital; Carelon Research

Active, not recruiting

The Impact of Diabetes on REvascularization (TIDE)

Diabetes Mellitus | Peripheral Arterial Disease

United States, Canada, Finland
Klaus Reither
Radboud University Medical Center; Charite University, Berlin, Germany; University... and other collaborators

Completed

Diagnostic Accuracy of CAD4TB and C-reactive Protein Assay as Triage Tests for Pulmonary Tuberculosis (TB TRIAGE+)

Covid-19 | HIV | Pulmonary Tuberculosis | Tuberculosis Diagnosis

Lesotho, South Africa
University of Cape Town
Medical University of Vienna; University of Washington

Completed

Acid-Base and Point of Care Ultrasound in Severe Preeclampsia

Pre-Eclampsia

South Africa
Ottawa Hospital Research Institute
Ontario Lung Association

Withdrawn

A RCT of Prednisone as Adjunctive Therapy for Hospitalized Patients With Pulmonary TB and HIV Co-infection

HIV Infections | Tuberculosis

Canada, South Africa
Pfizer

Completed

A Multicenter Extension Study of Taliglucerase Alfa in Pediatric Subjects With Gaucher Disease

Gaucher Disease

Israel, Paraguay, South Africa
University of Rochester NCORP Research Base
National Cancer Institute (NCI)

Completed

Effects of Transcutaneous Electrical Nerve Stimulation on Chemotherapy-Induced Peripheral Neuropathy

Chemotherapy-Induced Peripheral Neuropathy

United States
BioMarin Pharmaceutical

Active, not recruiting

Gene Therapy Study in Severe Hemophilia A Patients With Antibodies Against AAV5 (GENEr8-AAV5+)

Hemophilia A | Gene Therapy | Blood Disorder | Clotting Disorders

Taiwan, Korea, Republic of, United Kingdom, South Africa
Zimmer Biomet

Terminated

A Multicentre Trial to Compare Two Articulating Bearing Surfaces as Used in Cementless Primary Hip Arthroplasty (MagnumCRCT)

Osteoarthritis

Bosnia and Herzegovina, South Africa
Foundation for Innovative New Diagnostics, Switzerland
University of Cape Town; The Leona M. and Harry B. Helmsley Charitable Trust; University of Pretoria

Recruiting

Use of Continuous Glucose Monitoring Devices Among People Living With Type 1 Diabetes in South Africa (ACCEDE)

Type 1 Diabetes

South Africa
BioCryst Pharmaceuticals

Recruiting

Dose Escalation of BCX10013 in Subjects With Paroxysmal Nocturnal Hemoglobinuria

Paroxysmal Nocturnal Hemoglobinuria

South Africa, Malaysia
Swedish Orphan Biovitrum

Completed

Efficacy and Tolerability of Novel A2A Agonist in Treatment of Diabetic Neuropathic Pain

Diabetic Neuropathic Pain

Czech Republic, Germany, South Africa
DS Biopharma

Completed

Efficacy and Safety Study of Orally Administered DS107 in Moderate to Severe Atopic Dermatitis Patients

Atopic Dermatitis

United States, South Africa
Novartis

Completed

Safety and Tolerability of Omalizumab in Patients With Mild to Moderate Asthma

Asthma

Germany, South Africa
Boehringer Ingelheim

Completed

A Study of Single Dose Nevirapine (NVP) Combined With Combivir® for the Prevention of Mother to Child Transmission (pMTCT) - Treatment Options Preservation Study (TOPS)

Acquired Immunodeficiency Syndrome

South Africa
National Institute of Allergy and Infectious Diseases...

Completed

Safety, Tolerability and Acceptability of Long-Acting Cabotegravir (CAB LA) for the Prevention of HIV Among Adolescent Females - A Sub-study of HPTN 084

HIV Infections

Zimbabwe, South Africa, Uganda
Alvotech Swiss AG

Completed

AVT03 With Xgeva in Healthy Male Subjects

This is a Phase I Study Conducted in Healthy Volunteers

United Kingdom, South Africa, Poland
Medical University of Graz
Lagos State University; Walter Sisulu University; Management Sciences for Health and other collaborators

Enrolling by invitation

Effects of COVID-19 on Endothelium in HIV-Positive Patients in Sub-Saharan Africa (ENDOCOVID)

Covid19 | Hiv | ART

Nigeria, South Africa
University of Cape Town

Completed

Prevalence of Hyperglycemia and Anaemia in Elective Surgical Patients (EPIC-1)

Hyperglycemia | Anemia, Iron Deficiency

South Africa
HIV Vaccine Trials Network

Completed

Safety of and Immune Response to Vaccination With 2 Experimental HIV Vaccines in Healthy Adults (HVTN 097)

HIV Infection

South Africa
Michael Hoelscher
Radboud University Medical Center; University College, London; University of...

Recruiting

BTZ-043 Dose Evaluation in Combination and Selection (DECISION)

Tuberculosis, Pulmonary | Other Specified Pulmonary Tuberculosis

South Africa, Tanzania
Antiva Biosciences

Recruiting

A Study of ABI-2280 Vaginal Tablet in Participants With Cervical Intraepithelial Neoplasia

Cervical Intraepithelial Neoplasia

Australia, South Africa
International Maternal Pediatric Adolescent AIDS...
National Institute of Allergy and Infectious Diseases (NIAID); Comprehensive... and other collaborators

Terminated

Daily Isoniazid to Prevent Tuberculosis in Infants Born to Mothers With HIV

HIV Infection | Tuberculosis | Pneumocystis Jiroveci Pneumonia

Botswana, South Africa
National Institute for Communicable Diseases, South...
Centers for Disease Control and Prevention; Fogarty International Center of... and other collaborators

Active, not recruiting

Household Study of COVID-19, Influenza and RSV Burden, Transmission Dynamics and Viral Interaction in South Africa (PHIRST-C)

Influenza | SARS-CoV-2 Infection | Respiratory Syncytial Virus (RSV)

South Africa
NYU Langone Health
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effects of Interferon-Gamma on Cavitary Pulmonary Tuberculosis in the Lungs

Tuberculosis | AIDS-related Complex

United States, South Africa
Drugs for Neglected Diseases
University of Cape Town; Medecins Sans Frontieres, Netherlands; UBS Optimus Foundation and other collaborators

Completed

Pharmacokinetics of Lopinavir/Ritonavir Superboosting in Infants and Young Children Co-infected With HIV and TB

Acquired Immunodeficiency Syndrome | Tuberculosis

South Africa
Karex Industries Sdn. Bhd.
Essential Access Health; Match Research; Sigma3 Services SARL

Recruiting

Evaluation of Synthetic Nitrile Male Condom Compared to Standard Latex Male Condom

Sexually Transmitted Diseases

United States, South Africa
Michael Hoelscher
Radboud University Medical Center; German Federal Ministry of Education and... and other collaborators

Completed

PanACEA Sutezolid Dose-finding and Combination Evaluation (SUDOCU)

Pulmonary Tuberculosis | Other Specified Pulmonary Tuberculosis

South Africa, Tanzania
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Establish The Benefits Of Using Various Starting Doses Of Atorvastatin On Achievement Of Cholesterol Targets (ACTFAST) (ACTFAST)

Diabetes Mellitus, Type 2 | Dyslipidemia | Peripheral Vascular Disease | Coronary Arteriosclerosis | Cerebrovascular Accident

Italy, Spain, Canada, United Kingdom, Cameroon
Brigham and Women's Hospital
University of California, Los Angeles; University of Stellenbosch; University... and other collaborators

Recruiting

Ultra-Short Course Bedaquiline, Clofazimine, Pyrazinamide and Delamanid Versus Standard Therapy for Drug-Susceptible TB (PRESCIENT)

HIV | Tuberculosis, Pulmonary

South Africa, Haiti
Global Alliance for TB Drug Development

Active, not recruiting

A Trial to Evaluate the Male Reproductive Safety of Pretomanid in Adult Male Participants With Drug Resistant Pulmonary Tuberculosis Volunteers (PaSEM)

Tuberculosis | Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant | Tuberculosis, MDR | Drug-Resistant Tuberculosis

Georgia, South Africa
Fundació Institut Germans Trias i Pujol
National Center for Tuberculosis and Lung Disease, Tbilisi, Georgia; Perinatal...

Recruiting

Adjunctive Acetylsalicylic Acid and Ibuprofen for Tuberculosis (SMA-TB)

Tuberculosis, Pulmonary | Tuberculosis Infection | Tuberculosis, MDR

South Africa, Georgia
Aeras
Statens Serum Institut

Completed

A Phase I Study of Safety & Immunogenicity of AERAS-456 in HIV-Neg. Adults Treated for Drug-susceptible Pulmonary TB (C-037-456)

Tuberculosis

South Africa

Clinical Trials on Peripheral Vascular Disease in South Africa

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