Clinical Trials on Pharmacokinetic Profile

Total 830 results

Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

Drug-drug Interaction Study With MDV3100 (ASP9785) and Gemfibrozil and Itraconazole

Healthy Subjects | Pharmacokinetics | Drug-Drug Interaction

France
Astellas Pharma Inc

Completed

A Study to Evaluate the Drug Interaction of ASP015K and Tacrolimus

Healthy | Pharmacokinetics of ASP015K and Tacrolimus

United States
Tunisian Association for Immuno-oncology Research

Not yet recruiting

Biomarkers in Patients With Metastatic Breast Cancer (BIOPEACE)

Identify the Number of Eligible Patients for Immunotherapy According to the Epidemiological and Biological Profile in Tunisia
Fundación FLS de Lucha Contra el Sida, las Enfermedades...

Completed

Clinical Trial to Evaluate Pharmacological Interactions Between γ-hydroxybutyrate (GHB) and Cobicistat (GHB_Cobi)

HIV | Pharmacokinetic Interactions

Spain
Sheffield Children's NHS Foundation Trust

Withdrawn

Gene Expression Profiles in CML Non-responders

Gene Expression Profiles in CML Non-responders

United Kingdom
Aker Biomarine Antarctic AS
BioTeSys GmbH

Completed

Uptake of an Omega-3 Oil in Healthy Adults

Pharmacokinetics | Absorption

Germany
Shire

Completed

A Double-Blind Multi-Dose Tolerability and Pharmacokinetic Study of Teduglutide

Pharmacokinetics and Safety of Elevated Doses

United States
Cui Yimin

Unknown

Impact of Biomarkers on Pharmacokinetics and Pharmacodynamics of Ticagrelor

Pharmacokinetics | Pharmacodynamics | Pharmacogenomics | Accurate Medication | Ticagrelor

China
University Medicine Greifswald

Completed

Oral Pharmacokinetics of Sulfasalazine, Paracetamol, Fexofenadine and Valsartan Using Different Administration Mediums

Pharmacokinetics | Magnetic Resonance Imaging | Administration, Oral
University of Kansas Medical Center
Thomas Jefferson University

Completed

Evaluation of Intravenous Ascorbic Acid

Safety and Pharmacokinetics of Intravenous Ascorbate

United States
Bausch & Lomb Incorporated

Completed

Tear Fluid Levels of Loteprednol Etabonate Ophthalmic Gel 0.5% Following a Single Instillation

Pharmacokinetics

United States
King Faisal Specialist Hospital & Research Center

Completed

The Placebo Effect May Involve Modulating Drug Bioavailability

Pharmacokinetics | Placebo Effect | Drug Half Life

Saudi Arabia
Johnson & Johnson Pharmaceutical Research & Development...

Completed

Bioequivalence Study of the Oral Contraceptive Tablet Containing Norgestimate (NGM)/Ethinyl Estradiol (EE) With or Without Folic Acid in Healthy Women.

Female Contraception | Contraception | Pharmacokinetics | Therapeutic Equivalency
Astellas Pharma Inc

Completed

A Study to Assess Drug Interaction of ASP015K and Midazolam

Healthy | Pharmacokinetics of ASP015K and Midazolam

United States
Dr Andrew Odur
Uganda Martyrs University, St. Francis Hospital Nsambya, Jerusalem IHS and...

Completed

Third Trimester Modified Biophysical Profile Scan for Predicting Fetal Outcome.

Perinatal Death | Third Trimester Modified Biophysical Profile Scan

Uganda
University of Florida
National Center for Complementary and Integrative Health (NCCIH); Thorne HealthTech...

Completed

Biomarker Changes and Anxiolytic Effects-Phase 2 (KavaPK)

Pharmacokinetics

United States
Hartford Hospital
Shionogi Inc.

Active, not recruiting

Cefiderocol Plasma Concentrations in Patients Receiving Renal Replacement Therapy

Pharmacokinetics

United States
Yiling Pharmaceutical Inc.

Completed

A Phase I Pharmacokinetics Study for KT07 Capsule

Pharmacokinetics | Healthy Adult Subjects | Safety and Tolerability

United States
Joint Stock Company "Farmak"

Completed

Fed Bioequivalence Study of 2 Metformin 1000 mg Prolonged Release Tablets in 28 Healthy Male and Female Volunteers

Pharmacokinetics

Czechia
Daiichi Sankyo Co., Ltd.

Completed

A Study of the Effect of Quizartinib on the Pharmacokinetics of the P-gp Substrate Dabigatran Etexilate in Healthy Participants

Healthy Subjects | Pharmacokinetics | Drug-drug Interaction | Quizartinib

United States
Astellas Pharma Global Development, Inc.

Completed

A Phase I Study to Compare 3 Different Strengths of an Extended Release Formulation of ASP015K to an Immediate Release Formulation of ASP015K

Healthy Volunteers | Pharmacokinetics of ASP015K | Food Effect

United States
Astellas Pharma Europe B.V.

Completed

Study to Evaluate the Effect of Solifenacin and Mirabegron on the Tamsulosin Hydrochloride (HCl) Concentrations in Blood in Healthy Male Subjects

Healthy Subjects | Pharmacokinetics | Drug-Drug Interaction (DDI)

Germany
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Effect of Race on How a Single Dose of ASP3652 is Taken up, Metabolized and Distributed Through the Bodies of Young, Healthy Male and Female Subjects, and Its Safety and Tolerability

Healthy Subjects | Pharmacokinetics | Pharmacodynamics | Effect of Race

United Kingdom
University of North Carolina, Chapel Hill

Completed

Pharmacokinetic Study of Raltegravir in Healthy Premenopausal Women.

Pharmacokinetics

United States
Astellas Pharma Inc

Completed

Pharmacokinetic Interaction Study to Assess the Effect of ASP015K on Tacrolimus in Healthy Volunteers

Healthy Subjects | Drug Interactions | Pharmacokinetics of ASP015K

United States
Abbott Products
Quintiles, Inc.

Terminated

First in Man Study With SLV342

Pharmacokinetics

United Kingdom
Universidade Federal do Rio de Janeiro
Rio de Janeiro State Research Supporting Foundation (FAPERJ)

Completed

Microencapsulated Fish Oil or Conjugated Linoleic Acid in Metabolic Syndrome

Insulin Resistance | Blood Pressure | Oxidative Stress | Lipid Profile | Anthropometric Measure

Brazil
Il-Yang Pharm. Co., Ltd.

Not yet recruiting

Study to Evaluate the Safety and the Pharmacokinetics of IY-NT-T

Pharmacokinetics

Korea, Republic of
Joint Stock Company "Farmak"

Completed

Fed Bioequivalence Study of 2 Metformin 500 mg Prolongued Release Tablets in 28 Healthy Male and Female Volunteers

Pharmacokinetics

Czechia
Walter Reed Army Institute of Research (WRAIR)

Withdrawn

Malarone Pharmacokinetics Under Simulated Physiologic Stressors of Deployment (MPUSPSD)

Exercise | Pharmacokinetics

United States
Royal Brisbane and Women's Hospital
The University of Queensland

Completed

Pharmacokinetics of Ceftolozane/Tazobactam in Plasma and Cerebrospinal Fluid

Pharmacokinetics

Australia
Celgene

Completed

A Phase 1 Open-Label Study to Evaluate the Metabolism and Excretion of CC-223 and the Effect of Food on the Pharmacokinetics of CC-223 in Healthy Male Adult Subjects (AME/FE)

Safety and Pharmacokinetics in Healthy Volunteer Subjects

United States
Astellas Pharma Europe B.V.

Completed

Study to Evaluate the Effect of Solifenacin and Mirabegron on the Digoxin Concentrations in Blood in Healthy Subjects

Healthy Subjects | Pharmacokinetics | Drug-Drug Interaction (DDI)

Germany
Bayer

Completed

The Effect of Food (High Fat and Low Fat Breakfast) on the Pharmacokinetics of Regorafenib

Pharmacokinetics | Dietary Fats

United States
Astellas Pharma Inc

Completed

To Evaluate if Multiple Doses of Rifampicin Change the Blood Concentration of YM150 (Darexaban)

Healthy Subjects | Pharmacokinetics of Darexaban and Metabolites

France
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

Study to Evaluate the Pharmacokinetics of 14C-labeled Isavuconazole Following a Single Oral Dose of 14C-labeled Prodrug Isavuconazonium Sulfate (BAL8557) in Healthy Male Subjects

Healthy Subjects | Pharmacokinetics of 14C-labeled Isavuconazole

United States
University Hospital Birmingham NHS Foundation Trust

Completed

Blood Propofol Measurement During Anaesthesia Using Propofol Target Controlled Infusion

Pharmacokinetics | General Anaesthesia | Propofol | Target Controlled Infusion

United Kingdom
Astellas Pharma Inc

Completed

Pharmacokinetic Interaction Study to Assess the Effect of ASP015K on Mycophenolate Mofetil in Healthy Volunteers

Healthy Subjects | Drug Interactions | Pharmacokinetics of ASP015K

United States
Seoul National University Hospital

Completed

Clinical Trial to Evaluate the Influence of Genotype on the Pharmacokinetics/Pharmacodynamics of Clopidogrel

Influence of Genotype of Drug Metabolizing Enzyme or Transporter on the Pharmacokinetics/Pharmacodynamics of Clopidogrel | Influence of Aspirin on the Pharmacokinetics/Pharmacodynamics of Clopidogrel

Korea, Republic of
Tris Pharma, Inc.
Forest Laboratories

Completed

A Clinical Study to Evaluate the Effect of Renal Impairment on the Pharmacokinetics of Cebranopadol

Pharmacokinetic

United States
Geropharm

Recruiting

Double-blind, Randomized Comparative Cross-sectional Study of Pharmacodynamics and Pharmacokinetics of Drugs GP40141

Pharmacokinetics | Pharmacodynamics | Bioequivalence

Russian Federation
Cinclus Pharma AG

Recruiting

A Study to Investigate the Pharmacokinetics and ECG Effects of Linaprazan Glurate

GERD | Pharmacokinetics | Cardiodynamic ECG | Safety, and Tolerability

Sweden
Daiichi Sankyo Co., Ltd.

Completed

A Study of the Effect of a Moderate CYP3A Inducer Efavirenz on Quizartinib Pharmacokinetics in Healthy Participants

Healthy Subjects | Pharmacokinetics | Drug-drug Interaction | Quizartinib

United States
University of Florida
National Center for Complementary and Integrative Health (NCCIH); Thorne Research...

Completed

A Phased Clinical Trial of Dietary Supplemental Kava: Kava Pharmacokinetics (Kava PK)

Pharmacokinetics

United States
Food and Drug Administration (FDA)
Spaulding Clinical Research LLC

Completed

Clinical Study to Investigate the Urinary Excretion of N-nitrosodimethylamine (NDMA) After Ranitidine Administration

Pharmacokinetics | Food-drug Interaction | Ranitidine Adverse Reaction

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

Drug-Drug Interaction of SHR1459 With a Strong CYP3A Index Inducer (Rifampicin)

Healthy Subjects, Drug-drug Interaction, Pharmacokinetics, SHR1459

China
Astellas Pharma Global Development, Inc.

Terminated

A Phase 1, Dose Escalation Study to Assess the Safety and Tolerability of ASP9853 With Either Docetaxel or Paclitaxel in Patients With Advanced Non-hematologic Malignancies

Non-hematologic Malignancies | Pharmacokinetics of ASP9853

United States
Boryung Pharmaceutical Co., Ltd

Completed

Combination of Fimasartan/Amlodipine/Hydrochlorothiazide in Healthy Male Subjects

Pharmacokinetics

Korea, Republic of
International Partnership for Microbicides, Inc.

Completed

Expanded Use PK of Dapivirine Vaginal Ring

Pharmacokinetics
Utrecht University

Completed

The Relative Bio-availability of Oral and Oromucosal Melatonin in Different Formulations in Healthy Human Volunteers. (Melaform)

Pharmacokinetics of Melatonin

Netherlands

Clinical Trials on Pharmacokinetic Profile

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