Clinical Trials on Phrenic Nerve Irritation in Japan

Total 606 results

Bayer

Completed

To Evaluate the Safety, Tolerability, Pulmonary Deposition, Pharmacokinetics and Pharmacodynamics of Ciprofloxacin Inhale in Japanese Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD, GOLD II-III)

Pulmonary Disease, Chronic Obstructive

Japan
Boehringer Ingelheim

Completed

Long-term Use of Spiolto Respimat in Japanese Patients With Chronic Obstructive Pulmonary Disease

Pulmonary Disease, Chronic Obstructive

Japan
Kissei Pharmaceutical Co., Ltd.

Completed

Phase II Dose-Finding Study of KWA-0711 in Patients With Chronic Constipation (CC)

Chronic Constipation

Japan
University of Jazan

Completed

Comparison of Active Cycle of Breathing Technique and Pursed Lip Breathing With TheraPep

Chronic Obstructive Pulmonary Disease Exacerbation

Saudi Arabia
Chugai Pharmaceutical

Completed

A Study of Peginterferon Alfa-2a in Combination With Ribavirin in Chronic Hepatitis C (CHC) Patients With Compensated Liver Cirrhosis (LC)

Liver Cirrhosis | Chronic Hepatitis C

Japan
Astellas Pharma Inc

Completed

Post-Marketing Surveillance on Long-Term Drug Use of Kiklin (Bixalomer)® Capsules in Patients With Hyperphosphatemia Receiving Peritoneal Dialysis

Chronic Renal Failure

Japan
GlaxoSmithKline

Completed

Etiology of Acute Exacerbations of Chronic Obstructive Pulmonary Disease (AECOPD) in Japan

Pulmonary Disease, Chronic Obstructive

Japan
Osaka University
Merck Sharp & Dohme LLC; ISHIHARA SANGYO KAISHA,LTD. Japan

Unknown

Combination Therapy With GEN0101 and Pembrolizmub in Advanced Melanoma Patients PIb/PII

Advanced Melanoma

Japan
Astellas Pharma Inc

Completed

A Phase 2 Study of ASP1585 in Chronic Kidney Disease Patients With Hyperphosphatemia on Hemodialysis

Chronic Kidney Disease | Hyperphosphatemia

Japan
Jichi Medical University

Completed

Effects of Aliskiren in Elderly Hypertensive Chronic Kidney Disease (CKD) Patients

Hypertension | Chronic Kidney Disease

Japan
Otsuka Pharmaceutical Co., Ltd.

Completed

A Phase 2, Multi-center, Open-label, Dose-finding Trial to Investigate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of OPC-41061 in Patients With Chronic Renal Failure Undergoing Hemodialysis or Hemodiafiltration

Chronic Renal Failure

Japan
Hoffmann-La Roche
Chugai Pharmaceutical Co.

Terminated

A Study In Neuromyelitis Optica Spectrum Disorder (NMOSD) With Satralizumab As An Intervention (SAkuraBonsai)

Neuromyelitis Optica Spectrum Disorder | NMOSD

United States, Korea, Republic of, Italy, Canada, Japan, Turkey
Daiichi Sankyo Co., Ltd.

Active, not recruiting

A Study of DS-1001b in Patients With Chemotherapy- and Radiotherapy-Naive IDH1 Mutated WHO Grade II Glioma

WHO Grade II Glioma

Japan
GlaxoSmithKline

Completed

A Phase II, Open Label, Single Arm, Multicenter Study of Chlorambucil in Japanese Previously Untreated Patients With Chronic Lymphocytic Leukemia

Leukaemia, Lymphoblastic

Japan
Otsuka Pharmaceutical Co., Ltd.

Completed

Phase I Study of OPB-51602 in Patients With Hematologic Malignancies

Acute Myeloid Leukemia | Multiple Myeloma | Non-Hodgkin Lymphoma | Chronic Myeloid Leukemia | Acute Lymphoid Leukemia

Japan
Translational Research Center for Medical Innovation...
Yoyogi Sleep Disorder Clinic, Foundation of Sleep and Health Science

Completed

The Study of Combination Use of Melatonin Receptor Agonist for Dose Reduction or Interruptions of Benzodiazepine (BZD) and Non-BZD Hypnotics on Chronic Insomnia (BRED)

Chronic Insomnia

Japan
Kissei Pharmaceutical Co., Ltd.

Completed

A Exploratory Study of KWA-0711 in Patients With Chronic Idiopathic Constipation (CIC)

Chronic Idiopathic Constipation

Japan
CANDLE-KIT Trial Study Group
Chugai Pharmaceutical; Roche Diagnostics; The Japan Kidney Foundation; Japanese...

Terminated

Correcting Anemia and Native Vitamin D Supplementation in Kidney Transplant Recipients (CANDLE-KIT)

Renal Insufficiency, Chronic | Anemia | Vitamin D Deficiency | Kidney Transplantation

Japan
Kyoto University, Graduate School of Medicine
Philips Healthcare; Philips Respironics

Completed

The Effect of Adaptive Servo Ventilation and Oxygen Therapy in Central Sleep Apnea Patients

Sleep Apnea | Chronic Heart Failure

Japan
Shimousa Hematology Study Group
Epidemiological and Clinical Research Information Network

Unknown

Discontinuation of Dasatinib in Patients With Chronic Myeloid Leukemia-CP Who Have Maintained Complete Molecular Remission for Two Years; Dasatinib Stop Trial

Chronic Myeloid Leukemia

Japan
Ono Pharmaceutical Co. Ltd

Completed

Study of ONO-1078 in Patients With Chronic Sinusitis

Chronic Sinusitis

Japan
Pfizer

Completed

Efficacy And Safety Of Sunitinib In Patients With Advanced Well-Differentiated Pancreatic Neuroendocrine Tumors

Pancreatic Neuroendocrine Tumors

Japan
Kanazawa University

Unknown

Efficacy and Safety of Ursodeoxycholic Acid (UDCA) Added to the DPP-4 Inhibitor in People With Type 2 Diabetes and Chronic Liver Diseases

Type 2 Diabetes Mellitus | Chronic Liver Disease

Japan
Abbott

Completed

A Open-label Study to Assess the Safety of Oral Long-term Use of SA-001 in Pancreatic Exocrine Insufficiency

Pancreatic Exocrine Insufficiency, Chronic Pancreatitis, Pancreatectomy

Japan
Celgene Corporation

Terminated

Phase 1 Study of CC-486 in Japanese Subjects With Hematological Neoplasms

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Multiple Myeloma | Hodgkin Lymphoma | Chronic Myelomonocytic Leukemia | Non-Hodgkin Lymphoma

Japan
Rohto Pharmaceutical Co., Ltd.

Active, not recruiting

A Study to Investigate the Safety and Efficacy of UC-MSCs in Pediatric Patients With Cerebral Palsy

Cerebral Palsy | Periventricular Leukomalacia

Japan
Novartis

Completed

Dose Ranging Study of Indacaterol in Japanese Patients With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

Japan
Yokohama City University Medical Center

Terminated

the Effect of Febuxostat on Coronary Plaque Volume in Patients With Chronic Stable Angina and Hyperuricemia

Coronary Artery Disease

Japan
Bristol-Myers Squibb

Completed

Phase 2 Study of Ipilimumab Plus Dacarbazine in Japanese Patients With Advanced Melanoma

Melanoma

Japan
Bristol-Myers Squibb

Completed

Phase 2 Study of Ipilimumab in Japanese Advanced Melanoma Patients

Melanoma

Japan
Otsuka Pharmaceutical Co., Ltd.

Completed

Open-label Dose-finding Trial of OPC-41061 in Patients With Chronic Renal Failure Undergoing Peritoneal Dialysis

Chronic Renal Failure

Japan
Osaka University
Bayer

Enrolling by invitation

Lanthanum Versus Calcium Carbonate for Vascular Abnormalities in Patients With CKD and Hyperphosphatemia (LAVALIER)

Renal Insufficiency, Chronic | Bone Diseases, Metabolic | Hyperphosphatemia

Japan
Astellas Pharma Inc
FibroGen

Completed

A Study of Intermittent Oral Dosing of ASP1517 in Peritoneal Dialysis Chronic Kidney Disease Patients With Anemia

Peritoneal Dialysis Chronic Kidney Disease Patients With Anemia

Japan
Bayer

Completed

Study on the Safety of Drug BAY1817080 at Different Doses and the Way the Body Absorbs and Eliminates the Drug in Japanese Healthy Adult Male Participants

Overactive Bladder | Diabetic Neuropathic Pain | Endometriosis Related Pain | Refractory or Unexplained Chronic Cough

Japan
Novartis Pharmaceuticals

Completed

An East Asian Study of LDE225

Medulloblastoma | Basal Cell Carcinoma | Advanced Solid Tumor Cancers

Taiwan, Hong Kong, Japan
GlaxoSmithKline

Completed

Phase 3 Study of GSK548470 in Patients With Compensated Chronic Hepatitis B With Poor Response to Other Drugs

Hepatitis B, Chronic

Japan
Gilead Sciences

Completed

Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Idelalisib in Japanese Participants With Relapsed or Refractory Indolent B-Cell Non-Hodgkin Lymphomas (iNHL) or Chronic Lymphocytic Leukemia (CLL)

Follicular Lymphoma | Marginal Zone Lymphoma | Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma | Indolent Non-Hodgkin Lymphoma | Lymphoplasmacytic Lymphoma (With or Without Waldenstrom Macroglobulinemia)

Japan
Boehringer Ingelheim

Recruiting

DAREON™-7: A Study to Test How Well Different Doses of BI 764532 in Addition to Chemotherapy Are Tolerated by People With Advanced Neuroendocrine Cancers

Neuroendocrine Neoplasms

United States, Spain, Germany, Japan, France
Arash Aryana, MD

Completed

Comparison of Pulmonary Vein Ablation With or Without Left Atrial Posterior Wall Ablation for Persistent AF (PIVoTAL) (PIVoTAL)

Persistent Atrial Fibrillation | Atrial Fibrillation Chronic

United States, Japan
Takayuki Hamano
The Japan Kidney Foundation; Molecular Physiological Chemistry Laboratory,... and other collaborators

Completed

Cholecalciferol Supplementation for Anemia and Mineral and Bone Disorder in Hemodialysis Patients (CHAMBER)

Anemia | Vitamin D Deficiency | Kidney Failure, Chronic | Bone Diseases, Metabolic

Japan
Kochi University

Completed

Preoperative Oral Supplementation With Branched-Chain Amino Acids (BCAA) Improves Postoperative Quality of Life (KMS)

Hepatocellular Carcinoma | Chronic Liver Disease

Japan
Taiho Pharmaceutical Co., Ltd.

Recruiting

A Phase 2a Study of TAS5315 in Patients With Chronic Spontaneous Urticaria

Chronic Spontaneous Urticaria

Japan
AstraZeneca

Completed

OPTIMISE-CKD Drug Utilization (OPTIMISE-CKD)

Chronic Kidney Disease

United States, Japan, Sweden
Aarhus University Hospital
Nagoya University; Department of Pulmonary Circulation and Thromboembolic Diseases...

Recruiting

Hemodynamic Effects of BPA at Rest and During Exercise in CTEPH (EXPERT-BPA)

Chronic Thromboembolic Pulmonary Hypertension

Denmark, Japan, Poland
Sumitomo Pharma Co., Ltd.

Completed

A Study of DSP-7888 in Pediatric Patients With Relapsed or Refractory High Grade Gliomas

Glioblastoma | Diffuse Intrinsic Pontine Glioma

Japan
Astellas Pharma Inc

Completed

A Study of Oral Dosing of ASP0456 in Patients With Chronic Constipation

Chronic Constipation

Japan
Genzyme, a Sanofi Company

Completed

Evaluate the Safety and Tolerability of Vandetanib in Japanese Patients With Medullary Thyroid Carcinoma

Unresectable Locally Advanced or Metastatic, Medullary Thyroid Carcinoma

Japan
Bayer

Active, not recruiting

An Observational Study, Called FINEGUST, to Learn More About How People With Chronic Kidney Disease and Type 2 Diabetes Are Treated and How the Introduction of New Treatment Options, Like Finerenone, Impacts Clinical Practice (FINEGUST)

Type 2 Diabetes Mellitus | Chronic Kidney Disease

Japan, Spain, Netherlands, Denmark, United States
Abbott

Completed

Paricalcitol Injection Phase II Trial

Chronic Kidney Disease

Japan
Diagram B.V.
Johnson & Johnson; Biosense Webster, Inc.

Recruiting

CFAE/Spatiotemporal Dispersion Guided Ablation Versus PVI Guided Ablation in Persistent AF (CIPA)

Chronic Atrial Fibrillation

France, Netherlands, Japan

3

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