Clinical Trials on Pituitary ACTH Hypersecretion in Switzerland

Total 51 results

Novartis Pharmaceuticals

Completed

Efficacy and Safety Evaluation of Osilodrostat in Cushing's Disease (LINC-4)

Cushing's Disease

United States, China, Canada, Belgium, Thailand, Spain, Turkey, Brazil, Portugal, Russian Federation, Poland, Greece, Costa Rica, Switzerland
RECORDATI GROUP

Active, not recruiting

Study to Allow Access to Pasireotide for Patients Benefiting From Pasireotide Treatment in Novartis-sponsored Studies

Prostate Cancer | Neuroendocrine Tumors | Acromegaly | Cushing's Disease | Dumping Syndrome | Pituitary Tumors | Ectopic ACTH Secreting (EAS) Tumors | Melanoma Negative for bRAF | Melanoma Negative for nRAS

Belgium, Brazil, Bulgaria, Canada, France, Germany, Italy, Japan, Korea, Republic of, Thailand, Turkey, United States, Argentina, Greece, Hungary, India, Israel, Malaysia, Mexico, Netherlands, Peru, Poland, Portugal, Romania, Russian Federation and more
University Hospital, Basel, Switzerland

Recruiting

Semi-sitting Versus Supine Position in Endoscopic Skull Base Surgery (PosESS)

Pituitary Adenoma

Switzerland
University Hospital, Basel, Switzerland

Completed

Prediction of Sphenoid Septation in MRI Compared With CT and Intraoperative Findings During Endoscopic Pituitary Adenoma Surgery (Scope)

Pituitary Adenoma

Malaysia, Switzerland
University Hospital, Basel, Switzerland

Completed

Effects of IL-1 Beta on the HPA-axis in Obese Persons (CortIL)

Metabolic Syndrome | Hypersecretion; Cortisol

Switzerland
University Hospital, Basel, Switzerland
Kantonsspital Aarau

Completed

Copeptin as a Diagnostic Marker in the Management of Neurosurgical Patients With Disturbance of Water Homeostasis

Pituitary Adenoma

Switzerland
University of Zurich

Completed

Multicentric Prospective Validation of the Zurich Pituitary Score

Pituitary Adenoma

Switzerland, United States, Austria, Canada, Czechia, Italy
Insel Gruppe AG, University Hospital Bern

Terminated

Hyperprolactinemia and Adrenal Steroidogenesis (Prado)

Hyperprolactinemia

Switzerland
University Hospital, Basel, Switzerland

Completed

Copeptin as a Stress Marker During a Written Examination (CoEXAM)

Healthy

Switzerland
University of Zurich

Completed

Fetal Copeptin After Oxytocin Challenge Test (CopOCT)

Pregnancy

Switzerland
University Hospital, Basel, Switzerland

Completed

Effects of Empagliflozin an SGLT2-Inhibitor on Healthy Volunteers With Induced Hypotonic Hyponatremia - the DIVE Study (DIVE)

Inappropriate ADH Syndrome

Switzerland
University Hospital, Basel, Switzerland

Completed

Effects of the SGLT2-inhibitor Empagliflozin on Patients With SIADH - the SAND Study (SAND)

SIADH

Switzerland
University Hospital, Basel, Switzerland

Completed

The Influence of Water and Salt Intake on Copeptin Levels During Moderate Alcohol Consumption

Alcohol Drinking

Switzerland
University Hospital, Basel, Switzerland

Completed

Copeptin in the Diagnosis and Differential Diagnosis of Diabetes Insipidus. The CoSIP-Study

Diabetes Insipidus

Switzerland
University Hospital, Basel, Switzerland

Completed

Copeptin Changes After Food Intake (CoMeal)

Healthy Adults | Copeptin

Switzerland
Hospital Centre Biel/Bienne
Brahms AG

Completed

Assessment of Circulating Copeptin Levels in Healthy Subjects and Patients With Renal Insufficiency After Oral Water Load and Hypertonic Saline Infusion

Renal Failure | Hypoosmolality | Hyperosmolality

Switzerland
University Hospital, Basel, Switzerland

Completed

Study of Copeptin as a Diagnostic Marker for Acute Pancreatitis (COPA)

Pancreatitis | Acute Pancreatitis

Switzerland
University Hospital, Basel, Switzerland

Completed

Copeptin in Normal- to Hyperosmolar States

Copeptin Blood Values

Switzerland, Germany
University Hospital, Basel, Switzerland

Completed

Circulating Oxytocin Changes in Response to the Oxytocin System Stimulator MDMA in Patients With Diabetes Insipidus and Healthy Controls (OxyMA)

Diabetes Insipidus

Switzerland
University Hospital, Basel, Switzerland

Recruiting

Effects of Intravenous [Pyr1]Apelin-13 on Healthy Volunteers With Artificially Induced SIAD (ESCAPE)

Hyponatremia | SIAD - Syndrome of Inappropriate Antidiuresis

Switzerland
University Hospital, Basel, Switzerland
Swiss National Science Foundation

Completed

Copeptin After a Subcutaneous Stimulation With Glucagon in Adults (Glucacop)

Diabetes Insipidus

Switzerland
University Hospital, Basel, Switzerland

Completed

The Circadian Rhythm of Copeptin (Co-Rhythm)

Circadian Rhythm | Copeptin Blood Levels

Switzerland
University Hospital, Basel, Switzerland

Completed

Effects of the SGLT2-inhibitor Empagliflozin on Patients With Chronic SIADH - the SANDx Study (SANDx)

Hyponatremia | SIAD - Syndrome of Inappropriate Antidiuresis

Switzerland
University Hospital, Basel, Switzerland

Completed

Effect of Protein Supplementation on Plasma Sodium Levels and Urinary Urea Excretion in Patients With SIAD (TREASURE)

Syndrome of Inappropriate Antidiuresis (SIAD)

Switzerland
University Hospital, Basel, Switzerland

Completed

Copeptin After an Oral Stimulation With Macimorelin in Healthy Volunteers (Macicop)

Polyuria-polydipsia Syndrome

Switzerland
University Hospital, Basel, Switzerland

Completed

Effects of GLP-1 Analogues on Fluid Intake in Patients With Primary Polydipsia (The GOLD-Study) (GOLD)

Primary Polydipsia

Switzerland
University Hospital, Basel, Switzerland

Completed

Copeptin During a Standardized Psychological Stress Test (PsyCo)

Stress

Switzerland
University Hospital Inselspital, Berne

Terminated

The Influence of Different Hydrocortisone Replacement Doses on the Partitioning and Flexibility of Ectopic Lipids in Patients With Corticotropic Hypopituitarism (Hydrocort)

Hypopituitarism | Insulin Sensitivity | Hydrocortisone | Lipids | Fatty Acids, Nonesterified

Switzerland
University of Zurich

Completed

Mathematical Model for the Human Menstrual Cycle, Endocrinological Diseases and Fertility Treatment-PAEON (PAEON)

Polycystic Ovary Syndrome | Endometriosis | Hyperprolactinemia

Switzerland
University Hospital, Basel, Switzerland
Heinrich-Heine University, Duesseldorf

Completed

Perioperative Copeptin: Predictive Value and Risk Stratification in Patients Undergoing Major Surgery

Perioperative Myocardial Injury

Switzerland, Germany
University Hospital, Basel, Switzerland

Completed

Copeptin After Arginine Infusion in Polyuria-Polydipsia Syndrome

Healthy | Polyuria-polydipsia Syndrome

Switzerland
University Hospital, Basel, Switzerland

Completed

Copeptin for Risk Stratification in Non-traumatic Headache in the Emergency Setting - The CoHead Study (CoHead)

Head Pain

Switzerland
University Hospital, Basel, Switzerland

Completed

Copeptin in Outcome Prediction of an Acute Psychotic Episode (CoPsych)

Schizophrenia Spectrum and Other Psychotic Disorders | Bipolar Disorder | Acute Psychotic Episode | Affective Disorder

Switzerland
University Hospital, Basel, Switzerland

Recruiting

Oxytocin Substitution Therapy in Patients With Central Diabetes Insipidus (OxyTUTION)

Central Diabetes Insipidus (cDI)

Switzerland
University Hospital, Basel, Switzerland

Completed

The "COSMOS"-Study (Copeptin in Osmoregulation and Stress Assessment)

Stroke | Transient Ischemic Attack

Switzerland
Ipsen

Completed

Somatuline Predictive Factors in Acromegaly and NET (SOPRANo)

Acromegaly | Neuroendocrine Tumours

Switzerland, Austria, Germany
University Hospital, Basel, Switzerland
University Children's Hospital Basel

Completed

Copeptin for Prediction of Treatment Response in Children With Monosymptomatic Nocturnal Enuresis (MEN). (COMEN)

Nocturnal Enuresis

Switzerland
University Hospital, Basel, Switzerland

Completed

Use of Copeptin in Diabetes Insipidus

Diabetes Insipidus | Primary Polydipsia

Switzerland
University Hospital, Basel, Switzerland

Recruiting

Plasma Copeptin in Response to Oral Urea in Healthy Adults and Patients With Polyuria-polydipsia Syndrome (URANOS)

Primary Polydipsia | Arginine Vasopressin Deficiency

Switzerland
Novo Nordisk A/S

Completed

A Trial Investigating Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of a Single Dose of Long-acting Growth Hormone (Somapacitan) Compared to Daily Dosing of Norditropin® SimpleXx® in Children With Growth Hormone Deficiency

Growth Hormone Disorder | Growth Hormone Deficiency in Children

France, Israel, Austria, Spain, Switzerland, North Macedonia, Norway, Slovenia, Belgium, Sweden
Ipsen

Completed

Efficacy and Safety of Lanreotide Autogel (60, 90 or 120 mg) in Acromegalic Patients

Acromegaly

France, Switzerland
Novo Nordisk A/S

Completed

Effect of Growth Hormone on Bone Mineral Density in Young Adults With Child-hood Onset Growth Hormone Deficiency

Growth Hormone Disorder | Adult Growth Hormone Deficiency

Sweden, Austria, Spain, Switzerland, Germany, France, Australia, Poland, United Kingdom, Norway, Belgium, Hungary
University Hospital Inselspital, Berne
Charite University, Berlin, Germany; Goethe University; University of Basel

Completed

Copeptin for Risk Stratification in Acute Stroke Patients: the CoRisk Study (CoRisk)

Stroke | Transient Ischemic Attack

Germany, Switzerland
Novartis Pharmaceuticals

Completed

An Extension Study to Assess the Long-Term Safety and Efficacy of Pasireotide in Participants With Acromegaly

Acromegaly

Italy, Australia, Belgium, Germany, Switzerland, United States, France
Novartis Pharmaceuticals

Completed

Study to Evaluate the Efficacy and Safety of Sandostatin LAR at High Dose or in Combination Either With GH-receptor Antagonist or Dopamine-agonist in Acromegalic Patients (HOSCAR)

Acromegaly

Italy, France, Portugal, Poland, Switzerland
Charite University, Berlin, Germany
University Hospital, Basel, Switzerland; Heidelberg University; Universitätsklinikum... and other collaborators

Completed

Effect of the Biomarker Copeptin in Managing Patients With Suspected Acute Coronary Syndrome (ACS) (BiC-8)

Acute Myocardial Infarction

Germany, Switzerland, Austria
Novo Nordisk A/S

Active, not recruiting

A Research Study in Children With a Low Level of Hormone to Grow. Treatment is Somapacitan Once a Week Compared to Norditropin® Once a Day (REAL4) (REAL4)

Growth Hormone Deficiency in Children

United States, Korea, Republic of, United Kingdom, Canada, Russian Federation, India, Spain, Italy, Algeria, Austria, France, Ireland, Israel, Japan, Latvia, Poland, Serbia, Thailand, Ukraine, Germany, Slovenia, Switzerland
University Hospital, Basel, Switzerland
Erasmus Medical Center; Cambridge University Hospitals NHS Foundation Trust; Federal... and other collaborators

Completed

Use of Copeptin Measurement After Arginine Infusion for the Differential Diagnosis of Diabetes Insipidus - the CARGOx Study (CARGOx)

Diabetes Insipidus | Polydipsia, Primary

Switzerland, Netherlands, Brazil, Germany, Italy, United Kingdom
Sanofi

Completed

Safety and Efficacy of SR121463B in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH Safety)

Hyponatremia | Inappropriate ADH Syndrome

United States, France, Brazil, Russian Federation, Australia, Germany, Switzerland, Belgium, Hungary, Hong Kong, Canada
Novartis Pharmaceuticals

Completed

Safety and Efficacy of Pasireotide Long Acting Release (LAR) vs. Octreotide LAR in Patients With Active Acromegaly

Acromegaly

United States, Germany, Italy, Belgium, Taiwan, Turkey, Switzerland, Israel, Netherlands, Sweden, United Kingdom, Korea, Republic of, Spain, France, Canada, Greece, Russian Federation, Denmark, Mexico, China, Hungary, Norway, Argentina and more

Clinical Trials on Pituitary ACTH Hypersecretion in Switzerland

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