Clinical Trials on Platelet Refractoriness in Canada

Total 128 results

Ottawa Heart Institute Research Corporation

Completed

Platelet Function Monitoring in Patients Treated With Clopidogrel at the Time of Primary Percutaneous Coronary Angioplasty

Platelet Reactivity

Canada
BRADEN DULONG

Recruiting

Influence of Oxygenator Selection on Platelet Function and Rotational Thromboelastometry Following Cardiopulmonary Bypass

Cardiopulmonary Bypass | Platelet Dysfunction

Canada
Harrison, Theodore, M.D.

Unknown

Calculation of Platelet-rich Plasma Preparation Yield

Platelet-rich Plasma Production

Canada
Hamilton Health Sciences Corporation

Unknown

Reversal of the Antiplatelet Effects of Ticagrelor in Combination With Aspirin, Using Normal Platelets (REVSTARTS)

Aspirin | Platelet Dysfunction Due to Drugs | Ticagrelor | Transfusion

Canada
Université de Sherbrooke

Completed

Effects of Lovastatin on Human Platelet Proteome (LovaC)

Blood Platelets Proteome

Canada
Montreal Heart Institute
Institut de Recherches Cliniques de Montreal

Recruiting

Assessing Pharmacokinetics and Pharmacodynamics of Daily Enteric-coated Aspirin in Patients With StablE Diabetes II (APPEASEDII)

Diabetes Mellitus, Type 2 | Type 2 Diabetes | Platelet Aggregation | Aspirin | Platelet Aggregation Inhibitors

Canada
Damian Ratano
The PSI Foundation, Ontario

Active, not recruiting

Thrombo-Elastography Guided Management of ECMO (TEGMO)

Extracorporeal Circulation of Blood; Thrombocytopenia

Canada
McMaster University
Heart and Stroke Foundation of Ontario

Completed

Heparin-Induced Thrombocytopenia Score Card Study

Heparin-Induced Thrombocytopenia

Canada
University of Calgary

Completed

Effectiveness of Physiotherapy Following PRP for Chronic Whiplash

Whiplash Injuries | Neck Injuries | Platelet Rich Plasma

Canada
Ottawa Hospital Research Institute

Unknown

Optimizing the Diagnosis of Heparin Induced Thrombocytopenia (HIT)

Heparin-induced Thrombocytopenia (HIT)

Canada
Sanquin Research & Blood Bank Divisions
Terumo BCT

Completed

Pathogen Reduction Evaluation & Predictive Analytical Rating Score (PREPAReS)

Thrombocytopenia

Netherlands, Norway, Canada
McMaster University

Terminated

Rivaroxaban for Treatment of Patients With Suspected or Confirmed Heparin-Induced Thrombocytopenia

Heparin-induced Thrombocytopenia

Canada
Centre hospitalier de l'Université de Montréal...
Spine Intervention Society; Association Québécoise Médecine Sportive et Exercice

Completed

Comparison of IntraArticular Platelet-Rich-Plasma to Corticosteroid Injections for Patients With Zygapophyseal Joint (Z-Joint) Low Back Pain Confirmed by Dual Intra-Articular Local Anesthetic Injections

Low Back Pain | Zygapophyseal Joint Arthritis | Platelet Rich Plasma

Canada
Hamilton Health Sciences Corporation
University Health Network, Toronto; Dartmouth-Hitchcock Medical Center; Ottawa... and other collaborators

Terminated

Strategies for Transfusion of Platelets (SToP)

Thrombocytopenia

United States, Norway, Canada
The Hospital for Sick Children
Synapse B.V. Research Institute, University of Maastricht

Unknown

Point-of-care Assessment of Thrombin Generation and Platelet Function in Children Requiring Cardiopulmonary Bypass

Platelet Function Tests | Thrombin Generation Tests | Perioperative Coagulopathy

Canada
University Health Network, Toronto
Queen's University; Canadian Blood Services

Not yet recruiting

Delayed Cold-Stored Platelets -PLTS-1 (PLTS-1)

Bleeding | Cardiac Surgery | Cardiopulmonary Bypass | Platelets

Canada
Ottawa Hospital Research Institute

Recruiting

STrategies for Anticoagulation in Patients With thRombocytopenia and Cancer-associated Thrombosis

Thrombocytopenia | Cancer-associated Thrombosis

Canada
Korea University Anam Hospital

Recruiting

Platelet Activation Affecting the Rate of Vascular Access Patency

Platelet Activation | Hemodialysis Fistula Thrombosis

Korea, Republic of
CSL Behring

Completed

A Canadian Study to Assess the Safety of Humate-P® Ivr (Infusion Volume Reduced)

Von Willebrand Disease

Canada
Mansoura University

Active, not recruiting

A Randomized Trial to Evaluate Efficacy and Safety of Intracavernosal Injection of Platelet-Rich Plasma Versus Phosphodiesterase Type-5 Inhibitors for Treatment of Erectile Dysfunction.

Erectile Dysfunction Following Radiation Therapy | Phosphodiesterase Inhibitor Adverse Reaction | Platelet- Rich Plasma (PRP)

Egypt
Takeda

Completed

A Survey to Describe the Experience and Unmet Needs of Persons Living With Von Willebrand Disease (VWD) and Their Caregivers

Von Willebrand Disease (VWD)

Canada
McMaster University
St. Joseph's Healthcare Hamilton

Withdrawn

Cohort Study Comparing Short Daily Hemodialysis (HD) With Conventional HD

Cardiovascular Diseases | End-stage Renal Disease | Thrombocytopathy

Canada
Unity Health Toronto
University of Toronto; Li Ka Shing Knowledge Institute

Unknown

Proof-of-Concept: A Pilot, Randomized, Double-Blind Study of Oseltamivir Versus Placebo for Immune Thrombocytopenia

Immune Thrombocytopenia

Canada
Lawson Health Research Institute

Recruiting

A Prospective Study on the Long-Term Vascular Burden in Thrombotic Thrombocytopenic Purpura Patients (TTP)

Thrombotic Thrombocytopenic Purpura

Canada
The Hospital for Sick Children
Bayer

Completed

A Randomized Study of IVIG vs. IVIG With High Dose Methylprednisolone in Childhood ITP.

Immune Thrombocytopenic Purpura

Canada
Mount Sinai Hospital, Canada

Active, not recruiting

Venous Thromboembolism in Hematologic Malignancy and Hematopoietic Cell Transplant Patients: a Retrospective Study

Thrombocytopenia | Hematologic Malignancy | Venous Thromboembolic Disease | Thrombosis, Venous | Bleeding Hemorrhage

Canada
GlaxoSmithKline

Completed

Safety and Efficacy Study for Solid Tumor Patients Treated With Eltrombopag

Thrombocytopaenia

United States, Germany, Israel, Belgium, Finland, Ireland, Italy, Greece, India, Czech Republic, Hungary, Canada, Poland
Sanofi
Bristol-Myers Squibb

Completed

Platelet Aggregation Inhibition in Children on Clopidogrel (PICOLO)

Blood Platelet Disorders | Congenital Heart Defects

United States, France, Canada, Germany, Italy, Belgium
University of Calgary

Withdrawn

Shiga Toxin Producing Escherichia Coli (STEC) Volume Expansion

Hemolytic-Uremic Syndrome

Canada
London Health Sciences Centre

Withdrawn

The Plasma Large-Volume Exchange RCT (PLEX-RCT)

Purpura, Thrombotic Thrombocytopenic | Hemolytic Uremic Syndrome

Canada
World Federation of Hemophilia

Recruiting

World Bleeding Disorders Registry (WBDR)

Hemophilia A | Hemophilia B | Von Willebrand Diseases

Canada
Aspen Global Incorporated

Terminated

Open-Label, Randomised, Active Controlled, Multi-Centre Phase 3 Study Safety and Efficacy of Danaparoid vs Argatroban (HITSOVA)

Heparin-induced Thrombocytopenia

United States, Bosnia and Herzegovina, Canada, France, Germany, Italy, Poland, Russian Federation, Serbia
Ottawa Hospital Research Institute
Canadian Venous Thromboembolism Clinical Trials and Outcomes Research (CanVECTOR)... and other collaborators

Active, not recruiting

Assessing Feasibility of Thromboprophylaxis With Apixaban in JAK2-positive Myeloproliferative Neoplasm Patients (AIRPORT-MPN)

Primary Myelofibrosis | Venous Thromboembolism (VTE) | Polycythemia Vera (PV) | Essential Thrombocythemia (ET) | JAK2 Mutation | Myeloproliferative Neoplasm (MPN)

Canada
Hamilton Health Sciences Corporation
Hoffmann-La Roche

Completed

Pilot Study of Rituximab for the Treatment of Acute Immune Thrombocytopenic Purpura (ITP)

Purpura, Thrombocytopenic, Idiopathic

Canada
University Health Network, Toronto
Novartis Pharmaceuticals

Completed

Screening for Asymptomatic Portal Vein Thrombosis and Portal Hypertension in Patients With Philadelphia Negative Myeloproliferative Neoplasms

Myelofibrosis (MF) | Myeloproliferative Neoplasms (MPN) | Polycythemia Vera (PV) | Essential Thrombocythemia (ET)

Canada
Harokopio University
National and Kapodistrian University of Athens; University of Peloponnese

Unknown

Oleocanthal Rich Olive Oil Acute Effects on Hyperglycemia and Platelet Activation in T2DM

Inflammation | Oxidative Stress | Postprandial Hyperglycemia | Diabetes Mellitus, Adult-Onset | Platelet Dysfunction | Lipidemia

Greece
Janssen Research & Development, LLC

Recruiting

A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms

Neoplasms | Myeloproliferative Disorders | Essential Thrombocythemia | Myelofibrosis

United States, Spain, France, Canada
University of British Columbia
Centers for Disease Control and Prevention

Recruiting

Genomics and COVID-19 Vaccine Adverse Events

Vaccine Adverse Reaction

Canada
McMaster University
GlaxoSmithKline; Novartis; Hamilton Health Sciences Corporation

Completed

A Trial of Eltrombopag or Intravenous Immune Globulin Before Surgery for Immune Thrombocytopenia Patients

Immune Thrombocytopenic Purpura

Canada, Netherlands
Sierra Oncology, Inc.

Completed

Extension Study Evaluating the Long Term Safety and Efficacy Study of CYT387 in Primary Myelofibrosis (PMF) or Post-polycythemia Vera (PV) or Post-essential Thrombocythemia (ET)

Primary Myelofibrosis | Post-Polycythemia Vera Myelofibrosis | Post-Essential Thrombocythemia Myelofibrosis

United States, Canada, Australia
Sierra Oncology, Inc.

Completed

Safety Study Evaluating Twice-Daily Administration of Momelotinib in Primary Myelofibrosis or Post-Polycythemia Vera or Post-Essential Thrombocythemia Myelofibrosis

Primary Myelofibrosis | Post-Polycythemia Vera | Post-Essential Thrombocythemia Myelofibrosis

United States, Canada
Sierra Oncology, Inc.

Completed

Safety and Efficacy Study of CYT387 in Primary Myelofibrosis (PMF) or Post-polycythemia Vera (PV) or Post-essential Thrombocythemia (ET)

Primary Myelofibrosis | Post-Polycythemia Vera Myelofibrosis | Post-Essential Thrombocythemia Myelofibrosis

United States, Canada, Australia
Alexion Pharmaceuticals, Inc.

Recruiting

Ravulizumab in Thrombotic Microangiopathy After Hematopoietic Stem Cell Transplant

Thrombotic Microangiopathy

United States, Italy, Spain, Korea, Republic of, United Kingdom, Belgium, Netherlands, Germany, Japan, Greece, Brazil, Israel, France, China, Sweden, Australia, Canada, Poland
Alexion Pharmaceuticals, Inc.

Terminated

Ravulizumab in Thrombotic Microangiopathy Associated With a Trigger

Thrombotic Microangiopathy

United States, Belgium, France, Italy, Japan, Spain, Taiwan, United Kingdom, Canada, Korea, Republic of, Netherlands
Rallybio IPA, LLC

Recruiting

Study to Assess the Occurrence of HPA-1a Alloimmunization in Women With Higher Risk for Fetal and Neonatal Alloimmune Thrombocytopenia

Fetal and Neonatal Alloimmune Thrombocytopenia

United States, Canada, Netherlands, Norway, United Kingdom, Sweden, Germany
PharmaEssentia

Recruiting

A Single-arm, Multicenter Study to Assess the Efficacy, Safety, and Tolerability of P1101 in Adults With ET

Essential Thrombocythemia

United States, Canada
Alexion

Completed

Open Label Controlled Trial of Eculizumab in Adolescent Patients With Plasma Therapy-Sensitive aHUS (aHUS)

Atypical Hemolytic Uremic Syndrome

Canada, United Kingdom, France, Germany, Netherlands, Sweden, Italy
Eisai Inc.

Completed

Treatment of Thrombocytopenia in Patients With Chronic Liver DiseaseUndergoing an Elective Procedure

Thrombocytopenia Associated With Liver Disease

United States, Italy, China, Taiwan, Spain, Belgium, Poland, Portugal, Canada, Korea, Republic of, Australia, Brazil, Chile, Austria, Germany, Hungary, France, Argentina, United Kingdom, Thailand
Sierra Oncology, Inc.

Terminated

Safety and Efficacy of Momelotinib in Subjects With Polycythemia Vera or Essential Thrombocythemia

Polycythemia Vera | Essential Thrombocythemia

United States, France, Germany, Canada, Australia
John Mascarenhas
National Cancer Institute (NCI); Novartis; Incyte Corporation; Myeloproliferative...

Terminated

Ruxolitinib Prior to Transplant in Patients With Myelofibrosis

Primary Myelofibrosis | Post Essential Thrombocythemia Myelofibrosis | Post Polycythemia Vera Myelofibrosis

United States, Canada, United Kingdom

Clinical Trials on Platelet Refractoriness in Canada

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