Clinical Trials on Polysubstance Abuse

Total 1649 results

Duke University
National Institute on Alcohol Abuse and Alcoholism (NIAAA); UConn Health

Completed

Treatment for Teens With Alcohol Abuse and Depression (T-TAAD)

Depression | AOD Use, Abuse, and Dependence

United States
Kent State University

Completed

Examining Alcohol Consumption, Perceptions, and User Experience of Alcohol Moderation Strategies (ALCMOD)

Alcohol Use Disorder | Alcohol Abuse | Alcohol Abuse, Episodic

United States
University of Miami

Completed

Isolated During COVID-19: Effects of COVID-19's Social Restrictions on Loneliness and Psychosocial Symptomatology

Depression | Anxiety | Loneliness | Drug Abuse | Alcohol Abuse

United States
University of Miami
GlaxoSmithKline

Completed

Effect of an Inhaled Glucocorticosteroid (ICS) on Endothelial Dysfunction in Cigarette Smokers

Tobacco Abuse Smoke

United States
The University of Hong Kong

Completed

An Evaluation of the "Treatment Group Model for Abused Women" in Shelters in Hong Kong

Abused Women
Research Foundation for Mental Hygiene, Inc.
Columbia University

Not yet recruiting

Reducing Self-Stigma Among Individuals With History of Childhood Maltreatment: A Cross-Cultural Lens

Child Abuse | Stigma, Social | Help-Seeking Behavior | Child Neglect

United States
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

A118G SNP and OPRM1 Gene Opioid-Mediated Effects in Humans

Opioid Sensitivity | Individual Difference | Abuse Opioids

United States
University of Nebraska Lincoln
Centers for Disease Control and Prevention; The Set Me Free Project; Des Moines...

Recruiting

Preventing Commercial Sexual Exploitation of Children (Project LIVE)

Sexual Violence | Sex Trafficking | Child Abuse, Sexual | Sex Crimes | Commercial Sex | Sex Offense

United States
Queen Mary University of London
Barts & The London NHS Trust; University of Hertfordshire

Recruiting

Examination of Whether an Exercise Programme Reduces Alcohol Consumption Among Alcohol-Dependent Adults (AOA)

Alcohol Use Disorder | Alcohol Abuse or Dependence

United Kingdom
Canandaigua VA Medical Center

Withdrawn

Pilot the Use of VA Make the Connection Campaign to Facilitate Help Seeking Among Vulnerable Veterans

Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse) | Help-Seeking Behavior
Dartmouth-Hitchcock Medical Center
University of Miami; University of South Carolina; University of Massachusetts... and other collaborators

Completed

Clozapine for Cannabis Use in Schizophrenia (CLOCS)

Schizophrenia | Cannabis Dependence | Dual Diagnosis | Cannabis Abuse

United States
George Mason University
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Alcohol, Suicide and HIV Prevention for Teens in Mental Health Treatment

HIV | Suicide | Drug Abuse | Alcohol Abuse

United States
Member Companies of the Opioid PMR Consortium
Kaiser Permanente; World Health Information Science Consultants, LLC

Completed

An Observational Study to Develop Algorithms for Identifying Opioid Abuse and Addiction Based on Admin Claims Data

Opioid-Related Disorders | Drug Abuse | Opiate Addiction | Narcotic Abuse
Norwegian School of Sport Sciences

Withdrawn

Can Anti-asthmatic Medication Improve Sprint Performance in Healthy Endurance Athletes?

Sports Drug Abuse
National Institute on Drug Abuse (NIDA)

Completed

Quiting Marijuana Use: Self-report Study of Quitting Straegies and Withdrawal Symptoms

Cannabis Dependence | Cannabis Abuse

United States
Pfizer

Completed

Abuse Potential of Orally Administered Crushed Embeda Compared to Crushed Controlled-Release Morphine and Placebo in Non-Dependent Recreational Opioid Users

Nondependent Opioid Abuse, Episodic

United States
Bubba Nicholson
Tampa General Hospital; Otrimed Clinical Research

Unknown

Healthy Adult Male Facial Skin Surface Lipid Pheromone p.o. to Treat Opioid Addiction

Opioid-Related Disorders | Opioid Dependence | Opioid Use | Opioid Abuse | Opioid-use Disorder | Opioid Addiction | Opioid Intoxication | Opioid Abuse, Continuous Use | Paternal Pheromone Deficiency | Opioid Abuse, Episodic
Massachusetts General Hospital
Brigham and Women's Hospital

Active, not recruiting

EEG Monitoring in the Emergency Department

Substance Abuse | Drug Overdose | Alcohol Abuse

United States
Rush University Medical Center
Illinois Department of Human Services; Sparrow Mobile

Completed

Homeless Youth Study - Stepping Stone 2.0

Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)

United States
Kaiser Permanente
Kaiser Foundation Research Institute

Active, not recruiting

Continuing Care Following Drug Abuse Treatment: Linkage With Primary Care (Linkage)

Substance Abuse | Alcohol Abuse | Substance Dependence | Substance, Addiction

United States
Member Companies of the Opioid PMR Consortium
Columbia University; Research Foundation for Mental Hygiene, Inc.

Completed

Validation of PRISM-5-Op, Measure Of Addiction To Prescription Opioid Medication

Opioid-Related Disorders | Drug Abuse | Opiate Addiction | Narcotic Abuse
Member Companies of the Opioid PMR Consortium
HealthCore, Inc.

Completed

Study to Eval Relation Btw Doctor/Pharmacy Shopping & Outcomes of Misuse, Diversion, Abuse, Addiction by Med Rec Review

Opioid-Related Disorders | Drug Abuse | Opiate Addiction | Narcotic Abuse
University Hospital, Strasbourg, France

Not yet recruiting

Prevalence of Medical Care in an Emergency Structure of the Women Victims of Violence Within the Couple (Spousal-Abuse)

Spousal-Abuse

France
Karolinska Institutet
Universitätsklinikum Hamburg-Eppendorf; National Institute of Mental Health... and other collaborators

Recruiting

ReDirection - Self Help Program for Minor Attracted Individuals (ReDirection)

Pedophilia | Child Abuse Sexual

Czechia, Finland, Slovakia, Germany, Spain, Sweden
Yale University
National Institute on Drug Abuse (NIDA); VA Connecticut Healthcare System

Recruiting

PK/PD of Oral and Vaporized Delta-9-Tetrahydrocannabinol (THC) in Older Adults

Pain, Tolerance | Oral vs Vaporized THC | Abuse Liability

United States
University of Texas Southwestern Medical Center
National Institute on Drug Abuse (NIDA)

Active, not recruiting

Innovatively Increasing PCP Prescribing of Buprenorphine: Measurement Based Care and Integrated Electronic Solution (MBC4OUD)

Opioid Abuse and Addiction

United States
Member Companies of the Opioid PMR Consortium
World Health Information Science Consultants, LLC; IMS Health

Completed

Cross-Sectional Study to Define and Validate "Doctor/Pharmacy Shopping" as Outcomes Suggestive of Abuse and/or Addiction

Opioid-Related Disorders | Drug Abuse | Opiate Addiction | Narcotic Abuse
London School of Hygiene and Tropical Medicine

Completed

Conflict Between Maternal Autonomy and Child Health in Substance-use

Substance-Related Disorders | Substance Abuse, Intravenous | Alcohol-Related Disorders | Pregnancy | Marijuana Abuse | Opioid-Related Disorders | Cocaine-Related Disorders | Neonatal Abstinence Syndrome | Amphetamine-Related Disorders | Inhalant Abuse | Pregnancy, High-Risk

United Kingdom
Dartmouth-Hitchcock Medical Center
Janssen, LP

Completed

Risperidone Long-acting Versus Oral Risperidone in Patients With Schizophrenia and Alcohol Use Disorder

Psychotic Disorders | Schizophrenia | Substance Abuse | Alcohol Abuse

United States
University of Alabama at Birmingham

Completed

Healthcare Provider Attitudes Towards Patients With Substance Use Before and After Implementation of the SBIRT Model in the Emergency Room

Patients With Substance Abuse | Healthcare Provider Attitudes

United States
Karolinska Institutet
National Institute of Mental Health, Czech Republic; Linköping University,... and other collaborators

Recruiting

Mi Bridge - Motivational Interviewing to Facilitate Help-seeking Among Minor Attracted Individuals (Mi Bridge)

Pedophilia | Child Sexual Abuse

Germany, Czechia, Finland, Slovakia, Spain, Sweden
Bezmialem Vakif University

Completed

Ocular Effects of Synthetic Cannabinoids (Bonsai)

Eye Manifestations | Synthetic Cannabinoid Abuse (Disorder)

Turkey
Cristina Martínez Martínez
Hospital Clinic of Barcelona; Fundació Institut de Recerca de l'Hospital de... and other collaborators

Not yet recruiting

Characterization of the Pattern of Consumption and Withdrawal Syndrome From Dual Cannabis and Tobacco Use (DuCATA_GAMCaT)

Tobacco Use | Cannabis Dependence | Substance Abuse | Withdrawal Syndrome
National Institute on Drug Abuse (NIDA)

Completed

The Discriminative Effects of Tramadol in Humans

Opioid Abuse | Opioid Addiction | Stimulant Abuse | Stimulant Addiction

United States
Universitätsklinikum Hamburg-Eppendorf
Hoffmann-La Roche

Completed

Psychoeducation Reaches HCV-infected Methadone/Buprenorphine Substituted Patients in Standard Antiviral Treatment (Permit)

Intravenous Drug Abuse | Chronic Hepatitis C
T. John Winhusen, PhD
National Institute on Drug Abuse (NIDA); The Emmes Company, LLC

Recruiting

Medication Treatment for Opioid Use Disorder in Expectant Mothers: Infant Neurodevelopmental Outcomes Sub-study (MOMs-INO)

Pregnancy Related | Opioid-Related Disorders | Substance Abuse | Drug Abuse | Drug Addiction | Neonatal Abstinence Syndrome | Neonatal Opiate Withdrawal Syndrome | Drug Abuse in Pregnancy

United States
T. John Winhusen, PhD
National Institute on Drug Abuse (NIDA); The Emmes Company, LLC

Active, not recruiting

Medication Treatment for Opioid Use Disorder in Expectant Mothers (MOMs)

Pregnancy Related | Opioid-Related Disorders | Substance Abuse | Drug Abuse | Drug Addiction | Neonatal Abstinence Syndrome | Drug Abuse in Pregnancy | Neonatal Opioid Withdrawal Syndrome

United States
Jazz Pharmaceuticals

Completed

Abuse Potential of Sativex

Evaluation of Abuse Potential of Sativex

Canada
University of Houston

Unknown

Communication Skills vs. Mindfulness for IPV

Aggression | Domestic Violence | Family Conflict | Domestic Abuse
University of Toronto
Child Development Institute; Children's Aid Society of Toronto Child Welfare...

Unknown

Cluster RCT of Embedded Parenting Intervention to Prevent Recurrence and Reduce Impairment in Young Children Exposed to Domestic Violence (SafeUnderstood)

Child Abuse | Domestic Violence

Canada
Children's Hospital of Philadelphia
The Ray E. Helfer Society

Active, not recruiting

Effectiveness of Contrast-Enhanced Ultrasound

Abdominal Injuries | Accidental Fall | Physical Abuse | Motor Vehicle Injury

United States
Macmillan Research Group UK
Sonal Foundation, India

Completed

Role of Psychoanalysis in Prevention of Girl Child Maltreatment and Neglect

Abuse Neglect | Social; Deprivation, Maltreatment Syndrome (Infant or Child)

India
Adwin Life Care
Sonal Foundation, India; Gyaansanjeevani, Jhunjhunu, Rajasthan, India; Khatri...

Completed

Nursing Led Interdisciplinary Intervention in Prevention of Girl Child Mortality and Maltreatment

Abuse Neglect Social | Deprivation, Maltreatment Syndrome (Infant or Child)

India
Tampere University Hospital
Deaconess Foundation; A-Clinic Foundation

Recruiting

A Cross-Sectional Observational Study on Retained Drug Needle Fragments in People Who Use Intravenous Drugs

Soft Tissue Injuries | Substance Dependence | Foreign Bodies | Drug Abuse, Intravenous | Needle Injury

Finland
University of Cincinnati
National Institute on Drug Abuse (NIDA)

Completed

A Tailored, Peer-delivered Intervention to Reduce Recurring Opioid Overdoses (TTIP-PRO)

Opioid-Related Disorders | Substance Abuse | Drug Overdose | Drug Abuse | Drug Addiction

United States
Dartmouth-Hitchcock Medical Center
National Institute on Drug Abuse (NIDA); University of South Carolina; University... and other collaborators

Completed

Treatment of Schizophrenia and Comorbid Cannabis Use Disorder: Comparing Clozapine to Treatment-as-Usual

Schizophrenia | Schizoaffective Disorder | Dual Diagnosis | Cannabis Abuse | Psychotic Disorder

United States
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Employment-based Reinforcement of Naltrexone Ingestion and Abstinence

Substance Abuse, Intravenous | Opioid-Related Disorders | Heroin Dependence | Cocaine-Related Disorders

United States
National Institute on Drug Abuse (NIDA)

Completed

Health Outcomes by Neighborhood - Baltimore

Stigma | Activity Space | Social Networks | HIV Status | Drug Abuse/Dependence

United States
Dartmouth-Hitchcock Medical Center
AstraZeneca; Augusta University

Completed

Efficacy of Quetiapine in the Treatment of Patients With Schizophrenia and a Comorbid Substance Use Disorder

Schizophrenia | Schizoaffective Disorder | Substance Abuse | Alcohol Abuse | Psychotic Disorder

United States
The University of Texas Medical Branch, Galveston

Withdrawn

Open-Label Depakote ER in Patients With Bipolar I or II Depression and Alcohol Abuse or Dependence

Bipolar I or II Depression and Alcohol Abuse or Dependence

United States

Clinical Trials on Polysubstance Abuse

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