Clinical Trials on Positive End-Expiratory Pressure

Total 61613 results

University of Zurich
ETH Zurich

Recruiting

Comparison of Free-breathing 3D Quantitative Perfusion in Patients With MINOCA and MINOCA-mimics (COPE-CMR)

Non ST Elevation Myocardial Infarction | Myocarditis Acute | Takotsubo Cardiomyopathy | Spontaneous Coronary Artery Dissection | Myocardial Infarction With Non-Obstructive Coronary Artery

Switzerland
M.D. Anderson Cancer Center
Centers for Medicare and Medicaid Services

Completed

Cancer Prevention and Treatment Demonstration for Ethnic and Racial Minorities

Cervical Cancer | Breast Cancer | Colorectal Cancer | Lung Cancer | Prostate Cancer

United States
Universitätsklinikum Hamburg-Eppendorf

Recruiting

Chronical Illness-related Limitations of the Ability to Cope With Rising Temperatures: an Observational Study, 2nd Wave (CLIMATE-II)

Depressive Disorder | Myocardial Infarction | Heart Failure | Stroke | Coronary Disease | Diabetes Mellitus, Type 2 | Renal Insufficiency | Diabetes Mellitus, Type 1 | Schizophrenia | Pulmonary Disease, Chronic Obstructive | Peripheral Nervous System Diseases | Anxiety Disorders | Ischemic Attack, Transient | Arrhythmias... and other conditions

Germany
Universitätsklinikum Hamburg-Eppendorf

Terminated

Chronical Illness-related Limitations of the Ability to Cope With Rising Temperatures: an Observational Study (CLIMATE)

Depressive Disorder | Myocardial Infarction | Heart Failure | Stroke | Coronary Disease | Diabetes Mellitus, Type 2 | Renal Insufficiency | Diabetes Mellitus, Type 1 | Schizophrenia | Pulmonary Disease, Chronic Obstructive | Peripheral Nervous System Diseases | Anxiety Disorders | Ischemic Attack, Transient | Arrhythmias... and other conditions

Germany
Federal State Budget Institution Research Center...

Not yet recruiting

The Pilot Experimental Study of the Neuroprotective Effects of Exosomes in Extremely Low Birth Weight Infants

Premature Birth | Neurodevelopmental Disorders | Extreme Prematurity | Preterm Intraventricular Hemorrhage | Hypoxia-Ischemia, Cerebral

Russian Federation
Fondation Ophtalmologique Adolphe de Rothschild

Terminated

Impact of the Lockdown Due to the COVID Pandemic in French Wilson's Disease Patients (WILL-Ecco)

Wilson's Disease and COVID-19

France
Novartis Pharmaceuticals

Completed

Efficacy and Safety Study of Canakinumab Administered for 6 Months (24 Weeks) in Japanese Patients With Cryopyrin-associated Periodic Syndromes Followed by an Extension Phase

Familial Cold Autoinflammatory Syndrome | Muckle-Wells Syndrome | Neonatal Onset Multisystem Inflammatory Disease | Cryopyrin-associated Periodic Syndromes

Japan
Sidney Kimmel Comprehensive Cancer Center at Johns...
Maryland Cigarette Restitution Fund

Completed

Survivorship Promotion In Reducing IGF-1 Trial (SPIRIT)

Kidney Cancer | Breast Cancer | Pancreatic Cancer | Lung Cancer | Rectal Cancer | Prostate Cancer | Endometrial Cancer | Colon Cancer | Liver Cancer | Melanoma of Skin | Other Solid Malignant Tumors

United States
Novartis Pharmaceuticals

Completed

Efficacy, Safety and Tolerability of ACZ885 in Pediatric Patients With the Following Cryopyrin-associated Periodic Syndromes: Familial Cold Autoinflammatory Syndrome, Muckle-Wells Syndrome, or Neonatal Onset Multisystem Inflammatory Disease

Familial Cold Autoinflammatory Syndrome | Muckle-Wells Syndrome | Neonatal Onset Multisystem Inflammatory Disease | Cryopyrin-associated Periodic Syndromes

Germany, France, Belgium, Canada, Spain, Switzerland, United Kingdom
Tango Therapeutics, Inc.

Recruiting

Study of TNG260 and an Anti-PD Antibody in STK11 Mutated Solid Tumors

Cervical Cancer | Breast Cancer | Pancreatic Cancer | Non Small Cell Lung Cancer | Endometrial Cancer | Solid Tumors, Adult | Carcinoma of Unknown Primary

United States
University of Zurich

Recruiting

Intrathecal Double Checkpoint Inhibition (IT-IO)

Melanoma Stage IV | Leptomeningeal Metastasis | Non-small Cell Lung Cancer Stage IV

Switzerland
Huashan Hospital
The First Affiliated Hospital with Nanjing Medical University; The First Affiliated... and other collaborators

Recruiting

Real World Study of Classic Infectious Disease

Brucelloses | Epidemic Hemorrhagic Fever | Kala-Azar

China
Joanne Kurtzberg, MD

Available

Expanded Access Protocol: Umbilical Cord Blood Infusions for Children With Brain Injuries

Cerebral Palsy | Apraxia of Speech | Hydrocephalus | Hypoxia Ischemia, Cerebral | Drowning; Anoxia

United States
Institut Cancerologie de l'Ouest

Active, not recruiting

Impact of Therapeutic Patient Education on the Toxicity of Immune Checkpoint Inhibitors in Oncology (EDHITO)

Melanoma | Renal Cell Carcinoma | Head and Neck Cancer | Advanced Non-small Cell Lung Cancer | Immune Checkpoint Inhibitors | Therapeutic Patient Education | Immune-related Adverse Event

France
Novartis Pharmaceuticals

Completed

Efficacy, Safety and Tolerability of ACZ885 in Pediatric Patients With the Following Cryopyrin-associated Periodic Syndromes: Familial Cold Autoinflammatory Syndrome, Muckle-Wells Syndrome, or Neonatal Onset Multisystem Inflammatory Disease

Familial Cold Autoinflammatory Syndrome | Muckle-Wells Syndrome | Neonatal Onset Multisystem Inflammatory Disease | Cryopyrin-associated Periodic Syndromes

Germany, France, Belgium, Canada, Spain, Switzerland, United Kingdom
Mononuclear Therapeutics Ltd.
Chinese University of Hong Kong; China Spinal Cord Injury Network

Unknown

Feasibility and Safety of Umbilical Cord Blood Transfusion in the Treatment of Neonatal Cerebral Ischemia and Anemia

Anemia, Neonatal | Hypoxic-Ischemic Encephalopathy | Hypoxia Neonatal | Cerebral Ischemia of Newborn

Hong Kong
Imperial College London

Unknown

Cardiopulmonary Exercise Testing to Evaluate Pulmonary AVMs With and Without Airflow Obstruction (ExercisePAVM2)

Asthma | COPD | Hereditary Hemorrhagic Telangiectasia | Pulmonary Arteriovenous Malformations
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Lorvotuzumab Mertansine in Treating Younger Patients With Relapsed or Refractory Wilms Tumor, Rhabdomyosarcoma, Neuroblastoma, Pleuropulmonary Blastoma, Malignant Peripheral Nerve Sheath Tumor, or Synovial Sarcoma

Recurrent Neuroblastoma | Recurrent Rhabdomyosarcoma | Wilms Tumor | Recurrent Malignant Peripheral Nerve Sheath Tumor | Recurrent Synovial Sarcoma | Pleuropulmonary Blastoma

United States
University of California, San Francisco
Massachusetts General Hospital; Children's Hospital of Philadelphia; National... and other collaborators

Active, not recruiting

Neonatal Seizure Registry - Developmental Functional EValuation (NSR-DEV)

Stroke | Epilepsy | Cerebral Palsy | Intellectual Disability | Intracranial Hemorrhages | Hypoxic-Ischemic Encephalopathy | Neonatal Seizure

United States
Scripps Translational Science Institute
Cue Health

Active, not recruiting

ImmunoCARE: Rapid, Accurate COVID Testing to Reduce Hospitalization of Immunocompromised Individuals

HIV Infections | Lymphoma | Leukemia | Cancer | Multiple Myeloma | Immunosuppression | Immunodeficiency | Transplant | Graft Versus Host Disease | Age-Related Immunodeficiency

United States
Incyte Corporation

Completed

Arginase Inhibitor INCB001158 as a Single Agent and in Combination With Immune Checkpoint Therapy in Patients With Advanced/Metastatic Solid Tumors

Head and Neck Cancer | Gastric Cancer | Lung Cancer | Metastatic Cancer | Mesothelioma | Bladder Cancer | Solid Tumors | Renal Cell Carcinoma (RCC) | Colorectal Cancer (CRC) | UC (Urothelial Cancer)

Italy, Spain, United States, Netherlands
UCSF Benioff Children's Hospital Oakland
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Medical... and other collaborators

Completed

Multi-Center Study of Iron Overload: Survey Study (MCSIO) (MCSIO)

Sickle Cell Disease | Thalassemia | Diamond-Blackfan Anemia

United States, United Kingdom, Germany
National Cancer Institute (NCI)

Recruiting

Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations

Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Advanced Pancreatic Carcinoma | Metastatic Pancreatic Carcinoma | Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Castration-Resistant Prostate Carcinoma and other conditions

United States
Aga Khan University
The International Federation of Red Cross and Red Crescent Societies

Completed

Strengthening Maternal Neonatal and Child Health Services in a Rural District of Pakistan (SRC)

Pneumonia | Anemia | Eclampsia | Postpartum Hemorrhage | Diarrhoea | Neonatal Sepsis | Birth Asphyxia | Antepartum Hemorrhage
BeiGene

Active, not recruiting

Safety and Preliminary Effectiveness of BGB-A445 in Combination With Tislelizumab in Participants With Advanced Solid Tumors

Non Small Cell Lung Cancer | Advanced Solid Tumor | Head and Neck Squamous Cell Carcinoma (HNSCC) | Nasopharyngeal Carcinoma (NPC)

Canada, Australia, New Zealand, Korea, Republic of, United States, Malaysia, Thailand
Taipei Veterans General Hospital, Taiwan

Enrolling by invitation

Breathing-based Leg Resistance Exercise Improves Wound Healing, Blood Sugar and Quality of Life for Diabetic Foot Ulcers

Hyperglycemia | Quality of Life | Diabetic Foot | Wound Healing | Resistance Exercise
University of Southern California
National Cancer Institute (NCI)

Completed

18F-FMAU PET/CT and MRI for the Detection of Brain Tumors in Patients With Brain Cancer or Brain Metastases

Glioma | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Metastatic Melanoma | Metastatic Lung Carcinoma | Stage IV Lung Cancer AJCC v8 | Stage IV Renal Cell Cancer AJCC v8 | Stage IV Colon Cancer AJCC v8 and other conditions

United States
Eli Lilly and Company

Completed

A Study in Ovarian, Non-Small Cell Lung, Prostate, Colorectal, Gastroesophageal Cancers, and Squamous Cell Carcinoma of the Head and Neck

Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Ovarian Cancer | Prostate Cancer | Non Small Cell Lung Cancer | Cancer of Head and Neck

United States
Alpine Immune Sciences, Inc.

Recruiting

An Open-label Study of Povetacicept in Subjects With Autoimmune Cytopenias (RUBY-4)

Immune Thrombocytopenia | Idiopathic Thrombocytopenic Purpura | Cold Agglutinin Disease | Warm Autoimmune Hemolytic Anemia

United States, Canada, Australia, Turkey, United Kingdom, Italy, Spain
French Innovative Leukemia Organisation
Institut de cancérologie Strasbourg Europe

Completed

Observatory of Patients With Chronic Lymphocytic Leukemia / Lymphocytic Lymphoma or Waldenstrom Disease Infected With COVID-19 (COVID19_LLC-MW)

Chronic Lymphocytic Leukemia, Lymphocytic Lymphoma or Waldenstrom Disease

France
East Kent Hospitals University NHS Foundation Trust

Completed

Qualitative Study Patient & Physician Experiences Botox COVID-19 (QualBotoxCov)

Cerebral Stroke | Chronic Brain Injury | MS (Multiple Sclerosis)

United Kingdom
Institut Bergonié
Boehringer Ingelheim

Not yet recruiting

Targeting MDMD and PD1 in Tumors With Tertiary Lymphoid Structures (EMPIRE)

Colorectal Cancer | Non Small Cell Lung Cancer | Triple Negative Breast Cancer | Biliary Tract Cancer | Adult Soft Tissue Sarcoma

France
Aurigene Discovery Technologies Limited

Recruiting

A Phase 1 Clinical Trial of AUR106 in Patients With Relapsed Advanced Malignancies (JIVAN)

Kidney Cancer | Gastric Cancer | Non Small Cell Lung Cancer | Colon Cancer | Urothelial Carcinoma | Relapse | Esophagus Cancer | Advanced Malignant Neoplasm

India
Origin Sciences
Queen Mary University of London; Royal Devon and Exeter NHS Foundation Trust

Recruiting

Feasibility Study to Investigate Rectal Mucus in Aero-Digestive Tract Cancer. (ORI-EGI-03)

Pancreatic Cancer | Gastric Adenocarcinoma | Non Small Cell Lung Cancer | Bladder Cancer | Gall Bladder Cancer

United Kingdom
Cedars-Sinai Medical Center
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaborators

Unknown

Pulmonary Disease and Exercise Tolerance in Boys With Fabry Disease

Fabry Disease

United States
Regeneron Pharmaceuticals

Completed

Rilonacept for Treatment of Cryopyrin-Associated Periodic Syndromes (CAPS)

Genetic Diseases, Inborn | Familial Cold Autoinflammatory Syndrome (FCAS) | Familial Cold Urticaria | Muckle-Wells Syndrome (MWS)

United States
Xencor, Inc.
ICON plc

Active, not recruiting

A Study of XmAb®23104 in Subjects With Selected Advanced Solid Tumors (DUET-3) (DUET-3)

Renal Cell Carcinoma | Nasopharyngeal Carcinoma | Small Cell Lung Cancer | Hepatocellular Carcinoma | Advanced Solid Tumors | Non-small Cell Lung Carcinoma | Squamous Cell Carcinoma of the Head and Neck | Cervical Carcinoma | Endometrial Carcinoma | Urothelial Carcinoma | Colorectal Carcinoma | Pancreatic Carcinoma and other conditions

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Heated Intra-peritoneal Chemotherapy With Doxorubicin and Cisplatin for Abdominal for Pelvic Tumors in Pediatric Patients (TOASTIT)

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Recurrent Rhabdomyosarcoma | Refractory Rhabdomyosarcoma | Recurrent Colon Carcinoma | Recurrent Gastric Carcinoma | Recurrent Rectal Carcinoma | Refractory Sarcoma | Refractory Ovarian Carcinoma | Resectable... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Atezolizumab and Bevacizumab in Treating Patients With Rare Solid Tumors

Recurrent Peritoneal Malignant Mesothelioma | Recurrent Pleural Malignant Mesothelioma | Vaginal Squamous Cell Carcinoma, Not Otherwise Specified | Neuroendocrine Carcinoma | Pancreatic Neuroendocrine Tumor | Recurrent Merkel Cell Carcinoma | Recurrent Nasopharynx Carcinoma | Appendix Adenocarcinoma and other conditions

United States
University of South Florida
University of Pennsylvania; University of Toronto; University of Western Ontario...

Completed

Impact of Vasculitis on Employment and Income

Vasculitis | Microscopic Polyangiitis | Systemic Vasculitis | Takayasu's Arteritis | Cryoglobulinemic Vasculitis | Behcet's Disease | CNS Vasculitis | Temporal Arteritis | Polyarteritis Nodosa (PAN) | Urticarial Vasculitis | Henoch-Schoenlein Purpura | Wegener Granulomatosis | Eosinophilic Granulomatosis

United States
American College of Radiology
RTOG Foundation, Inc.

Recruiting

Testing the Safety of Giving a Standard Dose of Radiation Over a Shorter Period of Time for Patients Who Had Surgery for Intermediate-Risk Head and Neck Cancer

Head and Neck Cancer | Head and Neck Squamous Cell Carcinoma | Squamous Cell Carcinoma of the Larynx | Squamous Cell Carcinoma of the Oral Cavity | Squamous Cell Carcinoma of the Oropharynx

United States
McMaster University
Joseph Brant Hospital

Completed

The Effects of Whole-body Exercise to Improve Swallowing Function in Older Adults With Dementia

Parkinson Disease | Cough | Neuro-Degenerative Disease | Swallowing Disorder | Old Age; Dementia

Canada
Rigshospitalet, Denmark
Odense University Hospital; Aarhus University Hospital; Region Capital Denmark; Candys Foundation

Completed

Postoperative Pain, Why Still in Hospital and DAOH Following TORS for SCCUP & OSAS

Pain, Postoperative | Postoperative Pain | Analgesia | Surgery | Cancer of Head and Neck | Oropharyngeal Cancer | Carcinoma of Unknown Primary

Denmark
National Cancer Institute (NCI)

Recruiting

Evaluation for NCI Surgery Branch Clinical Research Protocols

Melanoma | Colorectal Cancer | Lung Cancer | Bladder Cancer | Synovial Cell Cancer

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Bortezomib, Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients Undergoing Donor Peripheral Blood Stem Cell Transplant For High-Risk Stage I or II Multiple Myeloma

Refractory Plasma Cell Myeloma | Recurrent Plasma Cell Myeloma | Plasma Cell Leukemia | Loss of Chromosome 17p | Autologous Hematopoietic Stem Cell Transplant Recipient

United States
University of Pennsylvania

Completed

Detection of Cerebral Ischemia With a Noninvasive Neurometabolic Optical Monitor (NNOM)

Ischemic Stroke | Traumatic Brain Injury | Subarachnoid Hemorrhage | Intracerebral Hemorrhage | Acute Anoxic Encephalopathy

United States
Shandong Cancer Hospital and Institute

Completed

The Use of 18F-ALF-NOTA-PRGD2 PET/CT Scan to Predict the Efficacy and Adverse Events of Apatinib in Malignancies.

Cervical Cancer | Stomach Cancer | Breast Cancer | Esophageal Cancer | Non-small Cell Lung Cancer | Ovary Cancer | Malignancies

China
National Cancer Institute (NCI)
AstraZeneca

Active, not recruiting

A Phase 2 Study of Cediranib in Combination With Olaparib in Advanced Solid Tumors

Metastatic Lung Non-Small Cell Carcinoma | Pancreatic Ductal Adenocarcinoma | Advanced Malignant Solid Neoplasm | Unresectable Pancreatic Carcinoma | Metastatic Pancreatic Adenocarcinoma | Stage III Pancreatic Cancer AJCC v6 and v7 | Stage IV Pancreatic Cancer AJCC v6 and v7 | Stage IIIA Lung Non-Small... and other conditions

United States, Canada
Southwest Oncology Group
Patient-Centered Outcomes Research Institute; National Cancer Institute (NCI)

Completed

S1415CD, Trial Assessing CSF Prescribing Effectiveness and Risk (TrACER) (TrACER)

Stage IIIA Non-Small Cell Lung Cancer | Stage IIIB Non-Small Cell Lung Cancer | Febrile Neutropenia | Stage 0 Breast Cancer | Stage IV Non-Small Cell Lung Cancer | Stage IV Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IA Breast Cancer | Stage IB Breast Cancer | Stage IIA Breast... and other conditions

United States, Puerto Rico
Momentum Data
Pfizer; University of Oxford; University of Surrey

Completed

The Epidemiology, Management, and the Associated Burden of Related Conditions in Alopecia Areata

Multiple Sclerosis | Pneumonia | Rheumatoid Arthritis | Systemic Lupus Erythematosus | Anxiety Disorders | Psoriasis | Asthma | Type 1 Diabetes | Graves Disease | Celiac Disease | Allergic Rhinitis | Urinary Tract Infections | Crohn Disease | Influenza | Ulcerative Colitis | Herpes Zoster | Herpes Simplex | Atopic Dermatitis | V... and other conditions

United Kingdom

Clinical Trials on Positive End-Expiratory Pressure

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