Clinical Trials on Postoperative Hypotension in South Africa

Total 547 results

Bristol-Myers Squibb
Sanofi

Completed

Irbesartan/Hydrochlorothiazide (HCTZ) Combination Therapy as First Line Treatment for Severe Hypertension

Hypertension

United States, Belgium, Canada, Germany, Russian Federation, France, Israel, Netherlands
Boehringer Ingelheim

Completed

Telmisartan (Micardis) and Ramipril (Altace) - Factorial Design Study for the Treatment of Hypertension

Hypertension

United States, Argentina, Canada, Chile, Mexico, Peru
Bayer

Active, not recruiting

A Study to Test the Effects of Riociguat in Patients With Pulmonary Hypertension Associated With Left Ventricular Systolic Dysfunction (LEPHT)

Hypertension, Pulmonary | Ventricular Dysfunction, Left

Belgium, France, China, Spain, Japan, United States, Singapore, Canada, Switzerland, Austria, Denmark, Germany, Italy, Australia, Czechia, Netherlands, Poland, United Kingdom
LifeBond Ltd.

Unknown

Efficacy and Safety of LifeSeal™ Kit for Colorectal Staple Line Sealing

Rectal Cancer | Anastomotic Leak

Israel, United States, Sweden, Italy, Belgium, Denmark, Netherlands
Durata Therapeutics Inc., an affiliate of Allergan...

Completed

Efficacy and Safety of Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections

Abscess | Cellulitis | Surgical Site Infection | Wound Infection

United States, Bulgaria, Estonia, Hungary, Israel, Korea, Republic of, Latvia, Lithuania, Romania, Russian Federation, Slovakia, South Africa, Taiwan, Ukraine
Gilead Sciences

Terminated

DORADO-EX: Long-Term Safety Extension Study to the Phase 3 DORADO Study (Protocol DAR-311) of Darusentan in Resistant Hypertension (Darusentan)

Hypertension

United States, Sweden, Argentina, Denmark, Brazil, Canada, France, United Kingdom
GlaxoSmithKline

Completed

The COREG And Lisinopril Combination Therapy In Hypertensive Subjects (COSMOS) Trial

Hypertension

United States
Boehringer Ingelheim

Completed

Safety and Efficacy of Daily Use of Micamlo® Combination Tablets AP in Patients With Hypertension

Hypertension

Japan
Alnylam Pharmaceuticals

Active, not recruiting

Zilebesiran as Add-on Therapy in Patients With Hypertension Not Adequately Controlled by a Standard of Care Antihypertensive Medication (KARDIA-2) (KARDIA-2)

Hypertension

United States, Canada, Latvia, Poland, United Kingdom, Germany, Lithuania, Estonia, Puerto Rico
Abbott
McKesson Canada

Completed

Canadian Study of Trandolapril on Blood Pressure in Hypertensive Patients (in-MAU-tion)

Hypertension

Canada
The Medicines Company

Completed

Clevidipine in the Treatment of Patients With Acute Hypertension and Intracerebral Hemorrhage (ACCELERATE) (ACCELERATE)

Hypertension | Hemorrhage

United States, Germany
Esperion Therapeutics, Inc.
Medpace, Inc.

Completed

Evaluation of ETC-1002 in Participants With Hypercholesterolemia and Hypertension

Hypertension | Hypercholesterolemia

United States
Gilead Sciences

Completed

DORADO - Fixed Doses of Darusentan as Compared to Placebo in Resistant Hypertension

Hypertension

United States, Spain, Germany, Argentina, Denmark, Brazil, Canada, France, Sweden, United Kingdom, Italy
Forest Laboratories

Completed

The Blood Pressure and Metabolic Effects of Nebivolol in Hypertensive Patients With Impaired Glucose Tolerance or Impaired Fasting Glucose

Hypertension

United States
Alnylam Pharmaceuticals

Recruiting

Zilebesiran as Add-on Therapy in Patients With High Cardiovascular Risk and Hypertension Not Adequately Controlled by Standard of Care Antihypertensive Medications (KARDIA-3) (KARDIA-3)

Hypertension | High Cardiovascular Risk

United States, Canada
University of New Mexico
Medical University of South Carolina; The Cleveland Clinic; Tufts Medical Center and other collaborators

Completed

Blood Pressure in Dialysis Patients (BID)

Hypertension | Blood Pressure | Dialysis | Renal Failure Chronic Requiring Hemodialysis

United States
InVasc Therapeutics, Inc.

Completed

INV-144 Versus Losartan in Hypertension and Type 2 Diabetes Mellitus Patients With Macroalbuminuria

Hypertension | Diabetes Mellitus, Type 2

United States
Forest Laboratories

Completed

The Effect of Nebivolol in Hypertensive Patients With Coronary Artery Disease

Coronary Artery Disease | Hypertension

United States
Bayer

Completed

Assessment of Efficacy of Vardenafil in Subjects With Erectile Dysfunction and Diabetes, Hypertension or Hyperlipidemia (LUTECIA)

Erectile Dysfunction

Israel, Italy, Colombia, Spain, Belgium, Finland, Mexico, Germany, South Africa, Netherlands, Norway, Peru, Sweden
Forest Laboratories

Completed

Study of the Glycemic Effects of Nebivolol Compared With Metoprolol and HCTZ in Diabetic Hypertensive Patients

Hypertension | Type 2 Diabetes Mellitus

United States, Puerto Rico
Ottawa Hospital Research Institute

Enrolling by invitation

Folic Acid Clinical Trial: Follow up of Children (FACT 4 Child)

Death | Asthma | Autism Spectrum Disorder | Pre-Eclampsia | Executive Dysfunction | Emotional Problem | Behavioural Problem

Australia, United Kingdom, Canada, Jamaica
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Open Label Study Assessing Effectiveness Of Amlodipine/Atorvastatin In Subjects With Hypertension and Dyslipidaemia (JEWEL I)

Hypertension | Dyslipidemia

Canada, United Kingdom
Société des Produits Nestlé (SPN)

Completed

A Study to Monitor the Use of an Amino Acid-Based Infant Formula (EAGLE)

Short Bowel Syndrome | Cow's Milk Protein Allergy | Eosinophilic Gastrointestinal Disorders | Malabsorption/Maldigestion | Multiple Food Allergies

United States
GlaxoSmithKline

Terminated

COREG MR Versus TOPROL-XL On Reduction Of Microalbuminuria In Patients With Hypertension And Microalbuminuria

Heart Failure, Congestive and Microalbuminuria

United States, Canada, Puerto Rico
Anesiva, Inc.

Completed

Prevention of Autogenous Vein Graft Failure in Peripheral Artery Bypass Procedures

Ischemia | Arterial Occlusive Diseases | Peripheral Vascular Diseases | Hyperplasia | Graft Occlusion, Vascular

United States, Canada
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Caduet vs Usual Care in Subjects With Hypertension and Additional Risk Factors (CRUCIAL)

Hypertension | Hypercholesterolemia

Costa Rica, Korea, Republic of, Panama, Turkey, Croatia, Taiwan, Dominican Republic, Thailand, Mexico, Russian Federation, Lebanon, United Arab Emirates, Malaysia, Philippines, Indonesia, Jordan, Czechia, Kuwait, Saudi Arabia, Venezuel...
Alterity Therapeutics

Recruiting

Study of ATH434 in Participants With Multiple System Atrophy

Multiple System Atrophy

United States, Australia, New Zealand, United Kingdom, Italy, France, Austria
AstraZeneca

Recruiting

A Phase III Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin on CKD Progression in Participants With CKD and High Blood Pressure.

Chronic Kidney Disease and Hypertension

Spain, United States, Argentina, Denmark, Italy, Sweden, United Kingdom, Belgium, France, Turkey, China, Germany, Saudi Arabia, Thailand, Vietnam, Australia, Serbia, Brazil, Canada, Japan, Malaysia, Philippines, Poland, Taiwan, Greece, Is... and more
UMC Utrecht
M.D. Anderson Cancer Center; University Health Network, Toronto; University of... and other collaborators

Completed

Predicting Reduction of Hypertension After Adrenalectomy for Primary Aldosteronism: a Multicenter Analysis

Primary Aldosteronism | Primary Aldosteronism Due to Aldosterone Producing Adenoma | Primary Aldosteronism Due to Conn Adenoma

United States, Netherlands, Australia, Canada, Italy
Takeda

Terminated

Efficacy and Safety of Azilsartan Medoxomil Used in Combination With Metformin in Participants With Hypertension and Diabetes

Hypertension | Diabetes

United States
Sanford Health
National Ataxia Foundation; Beyond Batten Disease Foundation; Pitt Hopkins Research... and other collaborators

Recruiting

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford (CoRDS)

Mitochondrial Diseases | Retinitis Pigmentosa | Myasthenia Gravis | Eosinophilic Gastroenteritis | Multiple System Atrophy | Leiomyosarcoma | Leukodystrophy | Anal Fistula | Spinocerebellar Ataxia Type 3 | Friedreich Ataxia | Kennedy Disease | Lyme Disease | Hemophagocytic Lymphohistiocytosis | Spinocerebellar Ataxia... and other conditions

United States, Australia
Boehringer Ingelheim
Eli Lilly and Company

Completed

24 Week Efficacy and Safety Study of Empagliflozin (BI 10773) in Hypertensive Black/African American Patients With Type 2 Diabetes Mellitus and Hypertension

Hypertension | Diabetes Mellitus, Type 2

United States
The George Institute
National Health and Medical Research Council, Australia

Completed

The Second Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT2)

Stroke | Hypertension | Intracerebral Hemorrhage

United States, France, Australia, Hong Kong, Finland, Germany, Spain, Argentina, Austria, Belgium, Brazil, Chile, China, India, Italy, Pakistan, Portugal, Switzerland, United Kingdom
The George Institute
The University of New South Wales

Recruiting

Triple Therapy Prevention of Recurrent Intracerebral Disease EveNts Trial (TRIDENT)

Hypertension | Intracerebral Haemorrhage (ICH)

United Kingdom, Australia, Singapore, Georgia, Netherlands, Nigeria, Sri Lanka, Switzerland, Brazil, Malaysia, Taiwan, Vietnam
KBP Biosciences

Active, not recruiting

Efficacy and Safety of KBP-5074 in Uncontrolled Hypertension and Moderate or Severe CKD (Clarion-CKD)

Chronic Kidney Diseases

China, Spain, Australia, Hungary, Malaysia, United States, Germany, Bulgaria, Serbia, Hong Kong, Georgia, Bosnia and Herzegovina, Croatia, Czechia, South Africa, Canada, Israel, Korea, Republic of, Latvia, Lithuania, Poland, Taiwan
Abbott

Completed

Effectiveness and Tolerability of Tarka® in the Treatment of Hypertensive Patients With High Risk of Developing Diabetes Mellitus (TARDIA)

Hypertension

Bulgaria, Czech Republic, Romania, Russian Federation, Slovakia, Slovenia, Ukraine
Galectin Therapeutics Inc.

Active, not recruiting

Study Evaluating the Efficacy and Safety of Belapectin for the Prevention of Esophageal Varices in NASH Cirrhosis (NAVIGATE)

Cirrhosis | NASH - Nonalcoholic Steatohepatitis | Prevention of Esophageal Varices

United States, France, Spain, Australia, Canada, Israel, Puerto Rico, Belgium, Argentina, Chile, Germany, Korea, Republic of, Mexico, Poland, United Kingdom
GlaxoSmithKline

Completed

Effect Of Carvedilol Versus Metoprolol On Glycemic Control In Patients With Type II Diabetes And Hypertension

Hypertension

United States
Duke University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) (POPS or POP02)

Heart Failure | Pain | Pneumonia | Hypertension | Edema | Hemophilia | Insomnia | Pulmonary Arterial Hypertension | Coagulation Disorder | Asthma in Children | Down Syndrome | Attention Deficit Hyperactivity Disorder | Bronchopulmonary Dysplasia | Hypokalemia | Hyperphosphatemia | Primary Hyperaldosteronism | Adrenal Insufficiency and other conditions

United States, Canada
AstraZeneca
Bristol-Myers Squibb

Completed

A Study of BMS-512148 (Dapagliflozin) in Patients With Type 2 Diabetes With Inadequately Controlled Hypertension on an ACEI or ARB and an Additional Antihypertensive Medication

Type 2 Diabetes

Australia, United States, Canada, Mexico, Puerto Rico, Germany, Hungary, Ireland, Poland, Romania, Denmark, Czech Republic, India, Colombia, Finland, United Kingdom
Boehringer Ingelheim

Completed

A Prospective, Randomised, Double-blind, Double-dummy, Forced-titration, Multicentre, Parallel Group, One Year Treatment Trial to Compare Telmisartan (MICARDIS) 80 mg Versus Losartan (COZAAR) 100 mg, in Hypertensive Type 2 Diabetic Patients With Overt Nephropathy (AMADEO Study)

Hypertension | Diabetic Nephropathies

Taiwan, United States, Canada, Thailand, Korea, Republic of, Argentina, Australia, Brazil, Mexico, New Zealand
AstraZeneca
Bristol-Myers Squibb

Completed

A Study of BMS-512148 (Dapagliflozin) in Patients With Type 2 Diabetes and Inadequately Controlled Hypertension on an Angiotensin-Converting Enzyme Inhibitor or Angiotensin Receptor Blocker

Type 2 Diabetes

Mexico, Russian Federation, Spain, United States, Canada, Puerto Rico, Hungary, Peru, Romania, Poland, Germany, Czech Republic, India, Colombia, Denmark, Finland
AstraZeneca
Bristol-Myers Squibb

Completed

Efficacy and Safety in Patients With Type 2 Diabetes Mellitus, Cardiovascular Disease and Hypertension

Hypertension | Cardiovascular Disease | Type 2 Diabetes Mellitus | Inadequate Glycaemic Control

United States, Vietnam, Germany, Romania, Canada, Argentina, Slovakia, Taiwan, Spain
AstraZeneca

Completed

European Study of Cardiovascular Risk (EURIKA)

Smoking | Hypertension | Obesity | Diabetes | Hyperlipidemia | Cardiovascular Risk Factors

Sweden, France, Russian Federation, Spain, Turkey, United Kingdom, Germany, Norway, Austria, Belgium, Switzerland, Greece
Medtronic Vascular

Recruiting

SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN

Cardiovascular Diseases | Vascular Diseases | Hypertension | Diabetes Mellitus | Chronic Kidney Diseases

United States, Monaco, Australia, Germany, France, United Kingdom, Belgium, Netherlands, Sweden, Greece
California Pacific Medical Center Research Institute
University of Pittsburgh; Duke University; National Institute on Aging (NIA); University... and other collaborators

Recruiting

Trial of Parkinson's And Zoledronic Acid (TOPAZ)

Parkinson Disease | Osteoporosis | Parkinsonism | Multiple System Atrophy | Progressive Supranuclear Palsy | Parkinson's Disease and Parkinsonism | Dementia With Lewy Bodies | Atypical Parkinsonism | Vascular Parkinsonism

United States
Daniel Benjamin
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care (PTN_POPS)

Heart Failure | Epilepsy | Pain | Pneumonia | Sepsis | Inflammation | Hypertension | Chronic Kidney Diseases | Hemophilia | Schizophrenia | Central Nervous System Infections | Nosocomial Pneumonia | Insomnia | Anxiety | Bipolar Disorder | Neutropenia | Staphylococcal Infections | Bradycardia | Seizures | Urinary Tract Infections | Pulmonary... and other conditions

United States, Canada, United Kingdom, Israel, Singapore

Clinical Trials on Postoperative Hypotension in South Africa

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Rwanda

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations