Clinical Trials on Presence of Inflammatory Cytokines

Total 464 results

Hospices Civils de Lyon

Unknown

Evaluation of Immunosuppression in Septic Shock: Biomarkers and Pharmacological Restoration (IMMUNOSEPSIS) (IMMUNOSEPSIS)

Immunology of Septic Shock

France
University Hospital for Infectious Diseases, Croatia
Croatian Science Foundation

Recruiting

The Role of Immune Semaphorins in Steatotic Liver Disease and Sepsis (SepsisFAT)

Sepsis | Immune Response | Steatosis of Liver

Croatia
TME Pharma AG

Completed

Pharmacokinetics/Pharmacodynamics of NOX-H94 in the Human Endotoxemia Model

Anemia of Chronic Disease

Netherlands
Zekai Tahir Burak Women's Health Research and Education...

Unknown

Role of 'Pentoxifylline and or IgM Enriched Intravenous Immunoglobulin in the Treatment of Neonatal Sepsis'

Sepsis of the Newborn

Turkey
University of Birmingham
Federico II University; University of Calgary; University of Milan; University...

Completed

OPtical Diagnosis Training to Improve Dysplasia Characterisation in IBD (OPTIC-IBD)

Inflammatory Bowel Diseases | Crohn Disease | Ulcerative Colitis | Polyp of Colon | Crohn Colitis | Dysplasia Colon | Dysplasia, Crohn Disease-Associated

Canada, United Kingdom, Italy
University of Aarhus

Completed

Study of CIDP Patients During IVIG Treatment

Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

Denmark
Groupe Hospitalier Paris Saint Joseph

Recruiting

Comparison of Quality of Life With or Without Automatic Seton Placement in Perianal Crohn's Fistula (SOPA)

Crohn Disease

France
Rutgers, The State University of New Jersey

Recruiting

IVIG vs SCIG in CIDP

Chronic Inflammatory Demyelinating Polyneuropathy | CIDP | Immunoglobulin Deficiency

United States
Shanghai Changzheng Hospital

Not yet recruiting

Treating Donors With Intravenous Immunoglobulin to Reduce Donor-Derived Infections

Bacteremia | Viremia | Acute Rejection of Renal Transplant
Bristol-Myers Squibb

Recruiting

A Study to Evaluate the Utilization, Effectiveness, and Quality of Life of Ozanimod in Participants With Ulcerative Colitis (COLIBRI)

Colitis, Ulcerative

Germany
University of Athens

Unknown

Reactivation of CMV Infection in Immunocompetent Patients Under Severe Stress (RECYSTRESS)

Stress, Physiological | Cytomegalovirus Viraemia | Receptor, Hormonal; Disorder | Other Deficiency of Cell-mediated Immunity

Greece
Centre Hospitalier Universitaire de Nice

Completed

Descriptive Analysis of Morphological Aspects of Nerve by Ultra-high Frequency Ultrasound (30-50MHZ) in Demyelinating Neuropathies: Inflammatory Demyelinating Polyneuropathy Chronic (IPDC), Neuropathy Multifocal Motor Block of Conducting (NMMBC) and Neuropathy With Antibody A MAG (EchoNerf)

Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

France
Zimmer Biomet

Active, not recruiting

Allofit® IT With HXPE in Total Hip Arthroplasty

Avascular Necrosis | Inflammatory Arthritis | Osteoarthritis, Hip | Post-Traumatic Osteoarthritis of Hip

Austria, France, Germany, Spain
Zhejiang University

Completed

Effect of the Intensity of Continuous Renal Replacement Therapy

Optimal Intensity of Renal Replacement Therapy on Sepsis Patients

China
University of Toronto
University Health Network, Toronto

Unknown

IVIg for Demyelination in Diabetes Mellitus (IDIDM)

Diabetes Mellitus | Peripheral Neuropathy | Chronic Inflammatory Demyelinating Polyneuropathy

Canada
Rigshospitalet, Denmark
Aarhus University Hospital; Octapharma Pharmazeutika Produktionsges.m.b.H.

Completed

Immunoglobulin Dosage and Administration Form in CIDP and MMN

Chronic Inflammatory Demyelinating Polyneuropathy | Hemolytic Anemia | Multifocal Motor Neuropathy

Denmark
Verona Pharma plc

Completed

SAD/MAD Study of a New Formulation of Nebulised RPL554 in Healthy Subjects and COPD Subjects

Chronic Obstructive Pulmonary Disorder | Inflammatory Disorder of the Respiratory Tract

United Kingdom
Encore Medical, L.P.

Terminated

Foundation Knee Study - Retrospective

Osteoarthritis | Post-traumatic Arthritis | Inflammatory Tissue Disorders | Arthritis Secondary to Other Diseases | Avascular Necrosis of the Femoral Condyles

United States
University of Sao Paulo

Active, not recruiting

Taurine Supplementation Associated or Not With Exercise: Effect on Browning of White Adipose Tissue in Elderly Women With Sarcopenic Obesity

Browning of Subcutaneous White Adipose Tissue Post Intervention | Metabolic and Inflammatory Variables Post Intervention

Brazil
Kyunghee University Medical Center

Not yet recruiting

A Prospective Study on the Comparison of Postoperative Pain According to the Use of Cocktail Therapy in Laminoplasty

Adverse Effects in the Therapeutic Use of Analgesic, Antipyretic and Anti-Inflammatory Drug, Unspecified
Jack Khouri

Not yet recruiting

Siltuximab for Cytokine Release Syndrome Prophylaxis Prior to tx w/ Teclistamab in RRMM

Multiple Myeloma | Refractory Multiple Myeloma | Cytokine Release Syndrome | Immune Effector Cell Associated Neurotoxicity Syndrome

United States
University of Roma La Sapienza

Not yet recruiting

Neurophysiological Assessment in Patients With Multiple Sclerosis

Multiple Sclerosis | Inflammatory Disease | Demyelinating Disease
YooJin Lee
Inje University; Gangnam Severance Hospital; Soonchunhyang University Hospital; Jeju National University Hospital

Unknown

Association Between Self-reported Web-based SCCAI and Health-related Quality of Life Index in UC Patients (UC)

Quality of Life | Ulcerative Colitis

Korea, Republic of
AbbVie (prior sponsor, Abbott)

Completed

A Study to Evaluate the Impact of Adalimumab on Quality of Life, Health Care Utilization and Costs of Ulcerative Colitis Subjects in the Usual Clinical Practice Setting (InspirAda)

Ulcerative Colitis
Ferring Pharmaceuticals

Completed

Canadian Active & Maintenance Modified Pentasa Study (CAMMP)

Active Ulcerative Colitis | Remission of Ulcerative Colitis

Canada
PhaseBio Pharmaceuticals Inc.

Terminated

Pemziviptadil (PB1046), a Long-acting, Sustained Release Human VIP Analogue, Intended to Provide Clinical Improvement to Hospitalized COVID-19 Patients at High Risk for Rapid Clinical Deterioration and Acute Respiratory Distress Syndrome (ARDS). (VANGARD)

Pneumonia | Respiratory Failure | Respiratory Insufficiency | COVID 19 | Acute Respiratory Distress Syndrome | SARS-CoV-2 | Coronavirus | Cytokine Storm | Pulmonary Edema | Cardiac Event | Respiratory Complication | Cardiac Dysfunction | Hypoxemic Respiratory Failure | Hypoxic Respiratory Failure | Cardiac Failure | Cardiac... and other conditions

United States
Centre Hospitalier Universitaire Dijon

Unknown

Study of Innate Host Immune Response to C. Glabrata Clinical Isolates Resistant to Echinocandins: Impact on the Management of Candidemia in High-risk Patients (CAHOHR)

Candidemia of C. Glabrata

France
Maimonides Medical Center

Active, not recruiting

Oral Aspirin + Ketamine as Adjunct to Oral Antidepressant Therapy for Depression

Analgesia | Depressive Symptoms | Major Depressive Disorder | Treatment Resistant Depression | Ketamine | Physiological Effects of Drugs | Analgesics, Non-Narcotic | Peripheral Nervous System Agents | Central Nervous System Depressants | Neurotransmitter Agents | Sensory System Agents | Anti-Inflammatory Agents and other conditions

United States
heba mostafa taher mostafa

Unknown

An Audit Study on Management of Neonates With Neonatal Sepsis Admitted to Asyut University Children Hospital (ASMNWNSATAUC)

Neonates Have Risk Factors or Manifestations of Sepsis

Egypt
Rennes University Hospital
Bayer

Terminated

The Inflammatory Process and the Medical Imaging in Patients With an Inflammatory Disease of the Central Nervous System. (USPIO-CIS)

Multiple Sclerosis (MS) | Inflammatory Disease

France
Sutep Jaruratanasirikul
Prince of Songkla University

Completed

Population Pharmacokinetics and Monte Carlo Dosing Simulations of Meropenem During the Early Phase of Severe Sepsis and Septic Shock in Critically Ill Patients in Intensive Care Units

Initial Phase of Severe Sepsis and Septic Shock

Thailand
Washington University School of Medicine
National Cancer Institute (NCI); Incyte Corporation; American Society of Hematology

Active, not recruiting

Study of Itacitinib for the Prophylaxis of Graft-Versus-Host Disease and Cytokine Release Syndrome After T-cell Replete Haploidentical Peripheral Blood Hematopoietic Cell Transplantation

Myelodysplastic Syndromes | Hodgkin Disease | Non-Hodgkin Lymphoma | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia

United States
Wake Forest University Health Sciences

Withdrawn

Telemedicine for Early Detection of Cytokine Release Syndrome and Neurotoxicity

Follicular Lymphoma | Diffuse Large B Cell Lymphoma | High-grade B-cell Lymphoma | Primary Mediastinal Large B Cell Lymphoma | Large B-cell Lymphoma
University of Pretoria

Completed

Efficacy of Using a Closing Pack to Reduce Postpartum Sepsis

Prevention of Postpartum Sepsis

South Africa
Karolinska University Hospital

Completed

Value of PCT When Diagnosing Candidemia

The Value of Procalcitonin in Patients With Suspected Candidemia

Sweden
Assistance Publique - Hôpitaux de Paris

Recruiting

Remyelination in Multiple Sclerosis: a PET-MR Longitudinal Study Investigating Individual Profiles of Myelin Repair and the Contribution of Neuroinflammation (SMARTinMS)

Multiple Sclerosis | Inflammatory Disease

France
Sutep Jaruratanasirikul
Prince of Songkla University

Completed

Piperacillin/Tazobactam in Critically Ill Patients With Severe Sepsis and Septic Shock

Early Phase of Severe Sepsis and Septic Shock

Thailand
Preeclampsia Foundation

Recruiting

The Preeclampsia Registry (TPR)

Toxemia | Eclampsia | Preeclampsia | HELLP Syndrome | Hypertensive Disorder of Pregnancy

United States
The Royal Orthopaedic Hospital NHS Trust
Stryker Nordic

Recruiting

A Comparison of Impingement Free Range of Motion With CT Scan After Manual and Robotic Total Hip Replacement

Post-traumatic Osteoarthritis | Inflammatory Arthritis | Hip Osteoarthritis | Avascular Necrosis of Hip | Congenital Hip Problems

United Kingdom
Zimmer Biomet

Completed

Metasul Monoblock Component™ Cup in a Hip Resurfacing Application With the Durom® Hip Resurfacing Femoral Component

Rheumatoid Arthritis | Inflammatory Arthritis | Osteoarthritis, Hip | Avascular Necrosis of Hip | Post-traumatic; Arthrosis

Germany
University of Roma La Sapienza

Completed

To Detect Cryoimmunologic Response Induced by Early Breast Cancer Ultrasound-guided Cryoablation (ICE-study)

Stage I Breast Cancer | Cancer, Treatment-Related | Systemic Inflammatory Response | Tumor of Breast

Italy
The University of New South Wales
Sydney Children's Hospitals Network; Women's and Children's Hospital, Australia

Completed

Immunogenicity of HPV Vaccine in Immunosuppressed Children

Kidney Transplant Infection | Juvenile Idiopathic Arthritis | Inflammatory Bowel Disease | Autoimmune Disease | Evidence of Liver Transplantation | Bone Marrow Transplant Infection

Australia
University Clinic Dr Dragisa Misovic-Dedinje
University Clinic Zvezdara

Unknown

Impact of Additional Treatment With Saccharomyces Boulardii on Quality of Life in Patients With Mild Forms of Ulcerative Colitis and Crohn Disease

Crohn Disease | Ulcerative Colitis
Washington University School of Medicine
St. Louis University

Terminated

Treatment Utility of Postpartum Antibiotics in Chorioamnionitis (TUPAC)

The Primary Outcome of This Study Will be the Rate of Endometritis

United States
University Hospital, Clermont-Ferrand

Completed

Diffusion Tensor Imaging in Chronic Inflammatory Demyelinating Polyneuropathy (PIDC) (PIDC)

CIDP (Chronic Inflammatory Demyelinating Polyradiculoneuropathy) | CMT (Charcot Marie Tooth Disease)

France
Smith & Nephew, Inc.

Recruiting

Study to Evaluate the Safety and Effectiveness of REAL INTELLIGENCE™ CORI™ in Unicondylar Knee Arthroplasty (UKA) Procedures (CORI RCT UKA)

Avascular Necrosis | Non-inflammatory Degenerative Joint Disease, Including Osteoarthritis | Requires Correction of Functional Deformity | Requires Treatment of Fractures That Were Unmanageable Using Other Techniques

New Zealand, Australia, Hong Kong
Shaare Zedek Medical Center

Completed

Manipulating the Microbiome in IBD by Antibiotics and FMT (FMT)

Exacerbation of Ulcerative Colitis | Ulcerative Colitis, Active Severe | Crohn's Colitis

Israel, Italy, Canada, Finland, Poland, Spain
AbbVie

Terminated

Fecal Calprotectin Levels, Quality of Life, and Workability in Patients Suffering From Ulcerative Colitis Under Adalimumab Therapy - AdaProQuo (AdaProQuo)

Moderate to Severe Ulcerative Colitis
National Center for Research Resources (NCRR)
Mayo Clinic

Completed

Phase III Randomized, Double-Blind, Placebo-Controlled Study of 3,4-Diaminopyridine for Demyelinating Polyneuropathy

Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
National Center for Research Resources (NCRR)
University of Vermont

Completed

Phase III Multicenter Double Blind Controlled Trial of Human Immune Globulin Therapy in Previously Untreated Patients With Chronic Inflammatory Demyelinating Neuropathy

Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

Clinical Trials on Presence of Inflammatory Cytokines

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CROs in Rwanda

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