Clinical Trials on Primary Immune Deficiency Disorders

Total 47346 results

Shire

Completed

Retrospective, Observational Chart Review Study Conducted in Poland to Document the Management and Clinical Outcome of CUVITRU and HYQVIA in Pediatric Participants (< 18 Years) With Primary Immunodeficiency (PID) (IG-TATRY)

Primary Immunodeficiencies (PID)

Poland
St George's, University of London
Bill and Melinda Gates Foundation; York Hospitals

Terminated

Reactogenicity and Immunogenicity of Vaginal CNgp140 (SG06RS02)

HIV Infections | Acquired Immune Deficiency Syndrome

United Kingdom
University of California, San Francisco

Recruiting

Autologous Gene Therapy for Artemis-Deficient SCID

Severe Combined Immunodeficiency

United States
St. Jude Children's Research Hospital

Active, not recruiting

Haplocompatible Transplant Using TCRα/β Depletion Followed by CD45RA-Depleted Donor Lymphocyte Infusions for Severe Combined Immunodeficiency (SCID)

Severe Combined Immunodeficiency

United States
Association Pour l'Aide a la Recherche en Immunologie...

Completed

Study Through Imaging of Visceral Lymphoid Organs in Patients With SCID Who Have Recieved Bone Marrow Allograft (LymphImaging)

Severe Combined Immunodeficiency

France
University of California, San Francisco

Terminated

Hematopoietic Stem Cell Transplantation (HSCT) for Children With SCID Utilizing Alemtuzumab, Plerixafor & Filgrastim

Severe Combined Immunodeficiency

United States
National Human Genome Research Institute (NHGRI)

Completed

Influences on Female Adolescents' Decisions Regarding Testing for Carrier Status of XSCID

Severe Combined Immunodeficiency

United States
Shanghai Children's Medical Center

Unknown

Clinical Characteristics and Genetic Profiles of Severe Combined Immunodeficiency in China

Severe Combined Immunodeficiency

China
National Human Genome Research Institute (NHGRI)

Completed

Gene Transfer Therapy for Severe Combined Immunodeficieny Disease (SCID) Due to Adenosine Deaminase (ADA) Deficiency: A Natural History Study

Severe Combined Immunodeficiency

United States
Rambam Health Care Campus

Completed

The Effect of Vitamin D Replacement on Airway Reactivity, Allergy and Inflammatory Mediators in Exhaled Breath Condensate in Vitamin D Deficient Asthmatic Children

Vitamin D Deficiency | Asthma

Israel
Mayo Clinic
Arizona State University

Completed

Screening for Metabolic Problems in Mothers of Children With Autism and Typically Developing Children

Pregnancy | Autistic Disorder | Folic Acid Deficiency

United States
Pharmacosmos A/S

Completed

An Extension Trial to Assess the Safety of Re-dosing of Iron Isomaltoside/Ferric Derisomaltose (Monofer®/Monoferric®) (FERWON-EXT)

Iron Deficiency Anemia | Iron Deficiency Anaemia

United States
University Hospital, Basel, Switzerland

Completed

Characteristics of Patients With Hypersensitivity Reactions to Intravenous Iron Infusions

Iron-deficiency | Hypersensitivity Reactions

Switzerland
Federal Research Institute of Pediatric Hematology...

Completed

Memory T-cell Infusion to Improve Immunity After TCR-alpha/Beta Depleted Hematopoietic Stem Cell Transplantation (45RA_NEG_DLI)

Leukemia, Myeloid, Acute | Opportunistic Infections | Graft vs Host Disease | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma | Bone Marrow Failure Syndromes | Immune Deficiency Disease

Russian Federation
Octapharma

Completed

CLINICAL PHASE III STUDY TO MONITOR THE SAFETY, TOLERABILITY AND EFFICACY OF SUBCUTANEOUS HUMAN IMMUNOGLOBULIN (OCTANORM) IN PATIENTS WITH PRIMARY IMMUNODEFICIENCY DISEASES, INCLUDING (BUT NOT LIMITED TO) THOSE WHO HAVE COMPLETED THE SCGAM-01 TRIAL

Primary Immunodeficiency

United States, Canada
Assiut University

Completed

Minipooled-IVIG in Primary Immunodeficiency Disease

Primary Immunodeficiency

Egypt
CSL Behring

Completed

Safety and Tolerability of Higher Infusion Parameters of IgPro20 (Hizentra) in Subjects With Primary Immunodeficiency (PID)

Primary Immunodeficiency

United States, Canada
IMMUNOe Research Centers

Completed

The Benefit of 5% IVIG for Patients With Primary Immunodeficiency Disorders Who Experience Adverse Events on 10% IVIG Preparations

Primary Immunodeficiency
Grifols Therapeutics LLC

Completed

Pharmacokinetics, Safety, and Tolerability of Subcutaneous GAMUNEX-C in Pediatric Subjects With Primary Immunodeficiency (KIDS)

Primary Immunodeficiency

United States
Gazi University

Recruiting

Investigation of the Effects of Pulmonary Rehabilitation in Children With Primary Immunodeficiency

Primary Immunodeficiency

Turkey
Grifols Therapeutics LLC

Completed

A Study to Evaluate IGSC 20% Biweekly Dosing in Treatment-Experienced Participants and Loading/Maintenance Dosing in Treatment-Naïve Participants With Primary Immunodeficiency

Primary Immunodeficiency

United States
Grifols Therapeutics LLC

Completed

Safety and Pharmacokinetics of IGSC 20% in Subjects With Primary Immunodeficiency

Primary Immunodeficiency

United States, Canada
Federal University of São Paulo
CSL Behring

Completed

Specific IgG Antibody in Patients With Primary Antibody Deficiencies Treated With Subcutaneous Immunoglobulin

Common Variable Immunodeficiency | Agammaglobulinemia

Brazil
Radboud University Medical Center

Unknown

The Prevalence of Vitamin D Deficiency and Effects of Vitamin D Supplementation in HIV-1 Infected Patients

HIV Infections | Vitamin D Deficiency

Netherlands
Community Research Initiative of New England
Merck Sharp & Dohme LLC

Withdrawn

A Pilot Study to Determine if Raltegravir Eradicates HIV From Peripheral Blood Mononuclear Cells

HIV Infections | Acquired Immune Deficiency Syndrome
Janssen Korea, Ltd., Korea

Completed

A Post Marketing Survey Study to Evaluate the Safety and Effectiveness of Intelence

Acquired Immune Deficiency Syndrome

Korea, Republic of
National Institute of Allergy and Infectious Diseases...

Completed

Analysis of the Immune Response to COVID-19 Vaccination and Outcomes in Individuals With and Without Immune Deficiencies and Dysregulations

Immunodeficiencies | Immune Dysregulations

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

Send-In Sample Collection to Achieve Genetic and Immunologic Characterization of Primary Immunodeficiencies

Primary Immunodeficiency

United States, Turkey, Italy
Prometic Biotherapeutics, Inc.
Atlantic Research Group

Completed

Study of ProMetic BioTherapeutics Immune Globulin Intravenous (Human) 10%

Primary Immunodeficiency

United States
Grifols Therapeutics LLC

Completed

Efficacy, Pharmacokinetics, Safety, and Tolerability of IGSC 20% in Subjects With Primary Immunodeficiency

Primary Immunodeficiency

Spain, France, Germany, United Kingdom, Australia, Czechia, Hungary, Poland, Sweden
University Hospital, Lille
Shire

Completed

IgG Level in Primary Immunodeficiency Switching From Standard SCIG to Every Other Week HyQvia

Primary Immunodeficiency

France
ASIS Corporation

Unknown

ASIS for GAMMAGARD in Primary Immunodeficiency (ASISinPI)

Primary Immunodeficiency

United States
Willem Daniel Francois Venter
Bill and Melinda Gates Foundation

Completed

Dose Optimisation of Stavudine for the Treatment of HIV Infection (D4T)

Human Immunodeficiency Virus | Acquired Immune Deficiency Syndrome

South Africa, India, Uganda
Meyer Children's Hospital IRCCS

Recruiting

Immunodeficiency and Cancer: Identification of Congenital Immune System Defects Underlying Paediatric Lymphomas

Immune Deficiency

Italy
Prothya Biosolutions

Completed

Treatment of Deficient Subclass or Anti-polysaccharide Antibody Response (Subklasse)

Infections | IgG Deficiency

Netherlands
Rush University Medical Center
Gilead Sciences; University of Chicago; University of Illinois at Chicago; Abbott; Ruth M. Rothstein CORE Center

Terminated

Immune Reconstitution of Lopinavir/Ritonavir-Based vs Efavirenz-based HAART in Advanced HIV Disease

Acquired Immune Deficiency Syndrome

United States
Yale University
Bristol-Myers Squibb; Merck Sharp & Dohme LLC

Completed

Pilot Study of a Raltegravir Based NRTI Sparing Regimen

HIV Infections | Human Immunodeficiency Virus | AIDS | Acquired Immune Deficiency Syndrome

United States
Umraniye Education and Research Hospital

Completed

Uroflowmetry Results and Vitamin D Levels

Lower Urinary Tract Symptoms | Vitamin D Deficiency | Calcium Deficiency
Baxalta now part of Shire

Completed

Safety, Pharmacokinetic and Efficacy Study of a 10% Triple Virally Reduced Intravenous Immune Globulin Solution in Patients With Primary Immunodeficiency (Hypo- or Agammaglobulinemia)

Primary Immunodeficiency Diseases (PID) | Hypogammaglobulinemia | Agammaglobulinemia

Finland, Sweden
Texas Tech University Health Sciences Center

Completed

Effect of Vitamin D Replacement on Insulin Sensitivity

Insulin Sensitivity

United States
Children's Hospital of Fudan University

Completed

Neonatal Screening of Severe Combined Immunodeficiencies

Severe Combined Immunodeficiency | Neonatal Screening

China
Azidus Brasil
Boya Bio Pharmaceutical Group Co Ltd

Not yet recruiting

Efficacy and Safety and Pharmacokinetics of Boya IVIG (Boya)

Primary Immunodeficiency Disease
Azidus Brasil
Sichuan Yuanda Shuyang Pharmaceutical Co., Ltd.

Not yet recruiting

Efficacy, Safety, and Pharmacokinetics of Shu Yang IVIG (Imunoforte)

Primary Immunodeficiency Disease
University of Zurich
University Hospital, Geneva; University of Lausanne; University of Bern; University... and other collaborators

Unknown

Clinical and Laboratory Online Patient- and Research Database for Primary Immunodeficiencies in Switzerland

Primary Immunodeficiency Disease

Switzerland
St Mary's University College

Unknown

The Associations Between Dietary Choline, Genetics and Anxiety/Depression

Depression | Anxiety | Choline Deficiency

United Kingdom
Ajou University School of Medicine

Unknown

IVIG Treatment for Asthmatic Patients With IgG Subclass Deficiency (IVIG)

Asthma
Columbia University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Vitamin D Repletion in Primary Hyperparathyroidism

Primary Hyperparathyroidism | Vitamin D Deficiency

United States
University Medical Centre Ljubljana

Recruiting

Nutritional Status of Women Undergoing in Vitro Fertilization

Body Weight | IVF | Nutrient Deficiency | Dietary Vitamin B12 Deficiency Anemia | Dietary Folate Deficiency Anemia

Slovenia
Akdeniz University

Completed

The Effect of Vitamin D on Fertility

Infertility | Vitamin D Deficiency | Infertility, Female | Vitamin D3 Deficiency

Turkey
University of Aarhus

Completed

Effect of Vitamin D Treatment in Primary Hyperparathyroidism

Primary Hyperparathyroidism | Vitamin D Deficiency | Hypercalcemia

Denmark

Clinical Trials on Primary Immune Deficiency Disorders

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