Clinical Trials on Primary Myelofibrosis

Total 59645 results

Sidney Kimmel Comprehensive Cancer Center at Johns...
Genzyme, a Sanofi Company

Terminated

Phase I Dose-Escalation Trial of Clofarabine Followed by Escalating Doses of Fractionated Cyclophosphamide in Children With Relapsed or Refractory Acute Leukemias (POE07-01)

Acute Myeloid Leukemia | Myeloproliferative Disorders | Myelofibrosis | Chronic Myelomonocytic Leukemia | Juvenile Myelomonocytic Leukemia | Acute Leukemia | Myelodysplastic Syndrome | Acute Lymphocytic Leukemia | Acute Promyelocytic Leukemia | Chronic Myelogenous Leukemia

United States, Canada
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Fludarabine Phosphate and Total Body Irradiation Followed by a Donor Peripheral Stem Cell Transplant in Treating Patients With Myelodysplastic Syndromes or Myeloproliferative Disorders

Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Chronic Myelomonocytic Leukemia | Myeloproliferative Neoplasm | Paroxysmal Nocturnal Hemoglobinuria | de Novo Myelodysplastic Syndrome | Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative | Refractory Anemia | Refractory Anemia With... and other conditions

United States
Janssen Research & Development, LLC

Recruiting

A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms

Neoplasms | Myeloproliferative Disorders | Essential Thrombocythemia | Myelofibrosis

United States, Spain, France, Canada
Marina Kremyanskaya

Recruiting

Mutant CALR-peptide Based Vaccine in Patients With Mutated CALR Myeloproliferative Neoplasm

Essential Thrombocythemia | Myelofibrosis | MPN

United States
Inge Marie Svane

Completed

CALR Exon 9 Mutant Peptide Vaccine to Patients With CALR-mutant Myeloproliferative Neoplasms

Essential Thrombocythemia | Myelofibrosis | Myeloproliferative Neoplasm, Unclassifiable

Denmark
National Human Genome Research Institute (NHGRI)

Completed

Genetic Analysis of Gray Platelet Syndrome

Myelofibrosis | Genetic Linkage

United States
University of Rochester

Not yet recruiting

A Telehealth Advance Care Planning Intervention (TeleSICP)

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Myelofibrosis | Myeloid Malignancy | Myelodysplastic/Myeloproliferative Neoplasm

United States
Masonic Cancer Center, University of Minnesota

Completed

Myeloablative Umbilical Cord Blood Transplantation in Hematological Diseases

Lymphoma | Acute Myeloid Leukemia | Myelodysplastic Syndromes | Leukemia | Multiple Myeloma | Non-Hodgkin's Lymphoma | Myelofibrosis | Chronic Lymphocytic Leukemia | Acute Lymphocytic Leukemia | MDS | Chronic Myelogenous Leukemia | Prolymphocytic Leukemia | Refractory Anemia

United States
Ottawa Hospital Research Institute
Canadian Venous Thromboembolism Clinical Trials and Outcomes Research (CanVECTOR)... and other collaborators

Active, not recruiting

Assessing Feasibility of Thromboprophylaxis With Apixaban in JAK2-positive Myeloproliferative Neoplasm Patients (AIRPORT-MPN)

Primary Myelofibrosis | Venous Thromboembolism (VTE) | Polycythemia Vera (PV) | Essential Thrombocythemia (ET) | JAK2 Mutation | Myeloproliferative Neoplasm (MPN)

Canada
AbbVie

No longer available

Expanded Access to Navitoclax

Myelofibrosis | Lymphoblastic Lymphoma | Acute Lymphocytic Leukemia (ALL)

United States
Novartis Pharmaceuticals

Recruiting

CINC424A2X01B Rollover Protocol

Acute Myeloid Leukemia | Primary Myelofibrosis | Polycythemia Vera | Thalassemia | Graft Versus Host Disease

Korea, Republic of, Italy, Belgium, Japan, Germany, Australia, Bulgaria, Chile, China, Denmark, Greece, Hungary, Israel, Lebanon, Poland, Portugal, Russian Federation, Slovakia, South Africa, Spain, Sweden, Thailand, India, Mexico, Turkey, Fran...
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Cyclophosphamide and Busulfan Followed by Donor Stem Cell Transplant in Treating Patients With Myelofibrosis, Acute Myeloid Leukemia, or Myelodysplastic Syndrome

Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia... and other conditions

United States
Millennium Pharmaceuticals, Inc.

Completed

A Phase 1 Dose Escalation Study of TAK-901 in Subjects With Advanced Hematologic Malignancies

Acute Myeloid Leukemia | Multiple Myeloma | Myelofibrosis | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Waldenstrom's Macroglobulinemia | Myelodysplastic Syndrome | Chronic Myelogenous Leukemia | Non-Hodgkins Lymphoma | Myeloid Metaplasia | Philadelphia Chromosome-negative CML | Advanced Polycythemia

United States
Eli Lilly and Company

Completed

Study of LY2784544 Testing Alternative Dosing in Participants With Myeloproliferative Neoplasms

Polycythemia Vera | Essential Thrombocythemia | Myelofibrosis | Myeloproliferative Neoplasms of

United States
Duke University

Completed

Total Body Irradiation With Fludarabine Followed by Combined Umbilical Cord Blood (UCB) Transplants

Lymphoma | Leukemia | Myelofibrosis | Solid Tumors | Myelodysplasia | Myeloma | Hodgkin's Disease

United States
Memorial Sloan Kettering Cancer Center

Recruiting

Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant Disorders

Hemoglobinopathies | AML | MDS | Bone Marrow Failure | ALL | Inherited Metabolic Disorders | HLH | MPD Withou Myelofibrosis | NHL or HL

United States
Hangzhou GluBio Pharmaceutical Co., Ltd.

Not yet recruiting

A Study of GLB-001 in Patients With Myeloid Malignancies

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Polycythemia Vera | Essential Thrombocythemia | Myelofibrosis | Myeloid Malignancy

China
Gruppo Italiano Trapianto di Midollo Osseo

Completed

Thymoglobuline Versus Alemtuzumab in Patients Undergoing Allogeneic Transplant (GLOBAL)

Myelofibrosis | Chronic Myeloid Leukemia | Lymphoblastic Leukemia | Myelodysplasia | Acute Myeloblastic Leukemia | Lympho-proliferative Diseases

Italy
IVI Bilbao
University of the Basque Country (UPV/EHU)

Withdrawn

Analysis of Lipid Profiles in Samples Sperm and Seminal Plasma Under Artificial Insemination

Primary Infertility

Spain
Karadeniz Technical University

Completed

Endometrial Injury and Single Embryo Transfer

Primary Infertility
University of California, Irvine

Completed

The NUTRIENT Trial (NUTRitional Intervention Among myEloproliferative Neoplasms): Feasibility Phase (NUTRIENT)

Polycythemia Vera | Essential Thrombocythemia | Myelofibrosis | Myeloproliferative Disorder | Myeloproliferative Syndrome

United States
Amro M. Hetta, M.Sc.
Mansoura University; Al-Azhar University

Not yet recruiting

First Clinical Live-Donor Uterus Transplantation Trial In Egypt

Primary Uterine Infertility

Egypt
Sahlgrenska University Hospital, Sweden
The Swedish Research Council

Completed

Uterus Transplantation From Live Donor (utx)

Primary Uterine Infertility

Sweden
The Cleveland Clinic

Enrolling by invitation

Uterine Transplantation for the Treatment of Uterine Factor Infertility

Primary Uterine Infertility

United States
University of Rochester

Completed

URMC Related Haplo-identical Donor BMT (HaploOnly)

Lymphoma | Multiple Myeloma | Myelofibrosis | Solid Tumors | Hematological Disease | Immune Deficiencies

United States
Ohio State University Comprehensive Cancer Center
Incyte Corporation; Jazz Pharmaceuticals

Recruiting

Testing the Effect of Taking Ruxolitinib and CPX-351 in Combination for the Treatment of Advanced Phase Myeloproliferative Neoplasms

Polycythemia Vera | Essential Thrombocythemia | Myelofibrosis | Secondary Acute Myeloid Leukemia | Myeloproliferative Neoplasm

United States
University of Rome Tor Vergata
University Of Perugia; University of L'Aquila

Completed

Intravesical Adjuvant Electromotive Mitomycin-C (EMDA/MMC)

Bladder Cancer TNM Staging Primary Tumor (T) Ta | Bladder Cancer TNM Staging Primary Tumor (T) T1 | Bladder Cancer Transitional Cell Grade

Italy
Incyte Corporation

Active, not recruiting

A Rollover Study to Provide Continued Treatment for Participants Previously Enrolled in Studies of Itacitinib

Chronic Graft Versus Host Disease | Myelofibrosis | Postlung Transplant (Bronchiolitis Obliterans)

United States, Spain, Italy, Germany, Belgium, Austria, Israel, Canada, Greece
Fondazione per la Ricerca Ospedale Maggiore

Completed

Secondary Cancers in Myeloproliferative Neoplasms (MPN-K Study) (MPN-K)

Polycythemia Vera | Essential Thrombocythemia | Myelofibrosis

Israel, United Kingdom, Czechia, Germany, Italy, Spain
Dartmouth-Hitchcock Medical Center

Completed

Myeloid-Derived Suppressor Cells and Checkpoint Immune Regulators' Expression in Allogeneic SCT Using FluBuATG (FluBuATG)

Myelodysplastic Syndromes | Leukemia, Myeloid | Multiple Myeloma | Lymphoma, Malignant | Myelofibrosis | Waldenstrom Macroglobulinemia | Leukemia, Lymphoid

United States
Shandong University

Withdrawn

Cell Cycle Regulatory Gene Study in Patients With Myeloproliferative Disorders

Myeloproliferative Disorders | Polycythemia Vera | Essential Thrombocythemia | Myelofibrosis | Chronic Myeloid Leukemia

China
Bayer

Completed

Second Primary Cancers in Patients With Castration Resistant Prostate Cancer (BOCARP)

Prostatic Neoplasms

Germany
Ain Shams Maternity Hospital

Unknown

Routine Hysteroscopy in IVF/ICSI Cycles in Patients With Primary Unexplained Infertility

Infertility | Pregnancy | Ovarian Hyperstimulation | Primary Infertility Unspecified
Taris Biomedical LLC
Bristol-Myers Squibb

Terminated

Safety and Tolerability of TAR-200 and Nivolumab in Subjects With Muscle-Invasive Bladder Cancer

Bladder Cancer TNM Staging Primary Tumor (T) T2 | Bladder Cancer TNM Staging Primary Tumor (T) T2A | Bladder Cancer TNM Staging Primary Tumor (T) T2B | Bladder Cancer TNM Staging Primary Tumor (T) T3 | Bladder Cancer TNM Staging Primary Tumor (T) T3A | Bladder Cancer TNM Staging Primary Tumor... and other conditions

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

The Patient Cohort of the National Center for Precision Medicine in Leukemia (eTHEMA)

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | High-risk Myelodysplastic Syndrome | Myeloproliferative Neoplasm, Unclassifiable | Secondary Myelofibrosis in Myeloproliferative Disease
MOHAMED BEHERY

Completed

AOA in Recurrent Fertilization Failure (AOA)

Infertility Primary

Egypt
Grand River Hospital

Unknown

Telemedicine Clinic for Prostate Cancer Patients

Cancer, Treatment-Related

Canada
H. Lee Moffitt Cancer Center and Research Institute

Completed

Calcineurin Inhibitor-Free GVHD Prevention Regimen After Related Haplo PBSCT

Myelodysplastic Syndromes | Primary Myelofibrosis | Multiple Myeloma | Hodgkin Lymphoma | Non-Hodgkin's Lymphoma | Chronic Myelomonocytic Leukemia | Chronic Myeloid Leukemia | Acute Leukemia in Remission

United States
Dicerna Pharmaceuticals, Inc.

Completed

A Study to Evaluate DCR-PHXC in Children and Adults With Primary Hyperoxaluria Type 1 and Primary Hyperoxaluria Type 2 (PHYOX2)

Kidney Diseases | Urologic Diseases | Genetic Disease | Primary Hyperoxaluria Type 1 (PH1) | Primary Hyperoxaluria Type 2 (PH2)

Poland, United Kingdom, New Zealand, United States, Australia, Canada, France, Germany, Israel, Italy, Japan, Lebanon, Netherlands, Romania, Spain
Astex Pharmaceuticals, Inc.

Terminated

Study to Assess the Safety of Escalating Doses of AT9283, in Patients With Leukemias

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Myelofibrosis | Acute Lymphoblastic Leukemia | Chronic Myeloid Leukemia

United States
University of Southern California
National Cancer Institute (NCI)

Recruiting

Curcumin to Improve Inflammation and Symptoms in Patients With Clonal Cytopenia of Undetermined Significance, Low Risk Myelodysplastic Syndrome, and Myeloproliferative Neoplasms

Polycythemia Vera | Essential Thrombocythemia | Myelofibrosis | Myelodysplastic Syndrome | Clonal Cytopenia of Undetermined Significance

United States
Singapore General Hospital
Shanghai Yueyang Integrated Medicine Hospital; Singapore Bao Zhong Tang TCM...

Completed

Traditional Chinese Medicine in the Supportive Management of Anaemic and Cytopenic (Leukopenia, Thrombocytopenia) Haematological Disorders

Myelodysplastic Syndrome (MDS) | Myelofibrosis (MF) | Thalassemia Intermedia | Aplastic Anaemia (AA)

Singapore
Johns Hopkins University
National Institute of Mental Health (NIMH); University of Michigan

Recruiting

Clinic-based HIV Identification and Prevention Project Using Electronic Resources (CHIPPER)

PrEP | HIV Prevention | Primary Care

United States
Alnylam Pharmaceuticals

Completed

Study of Lumasiran in Healthy Adults and Patients With Primary Hyperoxaluria Type 1

Primary Hyperoxaluria Type 1 (PH1)

France, United Kingdom, Netherlands, Israel, Germany
Istituto Clinico Humanitas

Completed

Retrospective Comparison of Pregnancy Outcome of Infertile Patients After Fresh and Warmed Single Blastocyst Transfer From 2014 to 2018.

Primary Maternal and Neonatal Outcomes; Assisted Reproductive Technology
National Taiwan University Hospital

Completed

Evaluation of Clinical Efficacy of Pentoxifylline on Patients With Glomerulonephritis

Primary Glomerulonephritis

Taiwan
University Hospital, Bordeaux

Completed

Impact of Local Biopsy to the Endometrium Prior to Controlled Ovarian Stimulation on Clinical Pregnancy (NIDABRECHE)

Primary or Secondary Infertility

France
Ankara City Hospital Bilkent

Completed

Ovarian Reserve and Matrix Metalloproteinases

Oxidative Stress | Ovarian Failure, Premature | Ovarian Insufficiency, Primary

Turkey
VA New York Harbor Healthcare System
Mayo Clinic; New York University

Unknown

Descriptive Analysis of Gut Microbiome Alterations in Hyperoxaluric Patients

Oxalate, Primary Hyperoxaluria, Microbiome

United States
Dicerna Pharmaceuticals, Inc.

Completed

Study to Evaluate Safety, Tolerability, PK and PD of DCR-PHXC in PH Type 3 Patients (PHYOX4)

Primary Hyperoxaluria Type 3

United States, Germany, Netherlands, United Kingdom

Clinical Trials on Primary Myelofibrosis

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