Clinical Trials on Primary Open-angle Glaucoma and Ocular Hypertension

Total 4208 results

Skye Bioscience, Inc.

Completed

Phase 2, Placebo-Controlled, Study Assessing the Safety and Ocular Efficacy of SBI-100 Ophthalmic Emulsion in Patients With Elevated Eye Pressure

Primary Open Angle Glaucoma | Ocular Hypertension

United States
Sun Pharmaceutical Industries Limited

Completed

A Therapeutic Equivalence Study in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension

Primary Open Angle Glaucoma | Ocular Hypertension

India, Russian Federation
MediPrint Ophthalmics, Inc.

Completed

Study of LL-BMT1 in Patients With Elevated Intraocular Pressure

Primary Open Angle Glaucoma | Ocular Hypertension

United States
Université de Sherbrooke

Completed

Generic Travoprost Versus Brand Name Travoprost in Patients With Primary Open Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma, Primary Open Angle

Canada
Bausch & Lomb Incorporated

Completed

A Phase 2, Dose Finding Study of PF-03187207 in Patients With Primary Open Angle Glaucoma or Ocular Hypertension.

Primary Open Angle Glaucoma | Ocular Hypertension

Japan
Chong Kun Dang Pharmaceutical

Unknown

A Clinical Study to Evaluate the Efficacy and Safety of CKD-351

Primary Open Angle Glaucoma | Ocular Hypertension

Korea, Republic of
Aristotle University Of Thessaloniki

Completed

24-Hour Intraocular Pressure (IOP) And Blood Pressure Control In Glaucoma And Ocular Hypertension Patients

Primary Open Angle Glaucoma | Ocular Hypertension

Greece
Altheos, Inc.

Unknown

Study of the Safety and Efficacy of ATS907 in Subjects With Primary Open Angle Glaucoma (POAG) and Ocular Hypertension

Primary Open Angle Glaucoma | Ocular Hypertension

United States
Altheos, Inc.

Completed

ATS907 Ph2a Open-Label Dose-ranging Safety and Tolerability in Primary Open Angle Glaucoma (POAG) and Ocular Hypertension (OHT) Subjects

Primary Open Angle Glaucoma | Ocular Hypertension

United States
Centre Hospitalier Universitaire, Amiens
Central Hospital Saint Quentin

Recruiting

Efficacy and Safety of iStent Inject and Inject W in the Management of Primary Open-angle Glaucoma (EII)

POAG | MIGS

France
CHU de Quebec-Universite Laval
Pfizer; Canadian Glaucoma Clinical Research Council

Completed

Impact Post-operative Treatment on Intraocular Pressure Post-SLT on Patients With Primary Open-angle Glaucoma (SLT)

Glaucoma | Inflammatory Response

Canada
Glaukos Corporation

Completed

A Prospective, Unmasked Evaluation of the iStent in Patients With Primary Open-Angle Glaucoma (SY)

Glaucoma | Glaucoma, Open-Angle | Eye Diseases

Spain, France, Armenia, Germany, Austria, Italy
Sooft Italia

Withdrawn

Effects of Forskolin on Intraocular Pressure in Glaucomatous Patients Under Maximum Tolerated Medical Therapy

Primary Open Angle Glaucoma | Intraocular Pressure

Italy
National Taiwan University Hospital Hsin-Chu Branch
Local clinic

Recruiting

Microinvasive Glaucoma Surgery -The Lowering Effect of Intraocular Pressure on Glaucoma Patients With High Frequency Deep Sclerotomy (HFDS)

Primary Open Angle Glaucoma | Intraocular Pressure | Glaucoma Surgery

Taiwan
AbbVie

Recruiting

A Study to Evaluate Adverse Events and Change in Disease Activity With the XEN45 Glaucoma Treatment System Implantation In Adult Participants With Open-Angle Glaucoma in China

Open-angle Glaucoma | OAG

China
EyeTechCare

No longer available

Ocular Fluorophotometry for Glaucoma Treated With Cyclo-coagulation Using High Intensity Focused Ultrasound (HIFU).

Refractory Open Angle Glaucoma
Transcend Medical, Inc.

Completed

CyPass Clinical Experience Study (CyCLE)

Open Angle Glaucoma (OAG)

Spain, Austria, Bulgaria, Germany, Italy, Poland
Alcon Research

Completed

Travoprost Five Day Posology Study

Ocular Hypertension | Open-angle Glaucoma (OAG)

United States
Betaliq, Inc.
Trial Runners, LLC; Summit Analytical, LLC

Completed

Nebivolol 0.5, 1.0, or Timolol 0.5 Suspension Compared to Timolol 0.5 Solution to Treat Glaucoma/Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma

United States
Glaukos Corporation

Completed

Subjects With Open-angle Glaucoma, Pseudoexfoliative Glaucoma, or Ocular Hypertension Naïve to Medical and Surgical Therapy, Treated With Two Trabecular Micro-bypass Stents (iStent Inject) or Travoprost

Open-angle Glaucoma

Armenia
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Study Demonstrating The Effect Of Latanoprost In Combination With Timolol, Latanoprost Alone And Timolol Alone On Eye Pressure In Open Angle Glaucoma Or Ocular Hypertension In Patients

Ocular Hypertension | Glaucoma | Open-angle Glaucoma

Germany
Allergan

Completed

Safety and Efficacy of a New Ophthalmic Formulation of Bimatoprost in Patients With Open Angle Glaucoma and Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma

United States, Israel, Canada, Singapore, Philippines, Spain, Australia, Belgium, Brazil, Germany
Aerie Pharmaceuticals

Completed

Double-masked Study of PG324 Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma

United States
Aerie Pharmaceuticals

Completed

Double-masked Study of PG324 Ophthalmic Solution in Patients With Open-angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma

United States
Santen Inc.

Completed

Multi-center Phase II Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension (SEE-1)

Ocular Hypertension | Open-angle Glaucoma

United States
Aerie Pharmaceuticals

Completed

Double-masked Study of AR-13324 Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension (Rocket-1)

Ocular Hypertension | Open-angle Glaucoma

United States
Aerie Pharmaceuticals

Completed

Evaluation of Netarsudil (AR-13324) Ophthalmic Solution in Patients With Glaucoma and Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma

United States
Mati Therapeutics Inc.

Completed

A Phase 2 Single-Masked, Randomized Study of Latanoprost PPDS in Ocular Hypertension or Open-Angle Glaucoma

Ocular Hypertension | Open-Angle Glaucoma

United States
Alcon, a Novartis Company

Completed

Comparison of Intraocular Pressure (IOP)-Lowering Efficacy and Safety of AZORGA® Ophthalmic Suspension and COSOPT® Ophthalmic Solution

Ocular Hypertension | Open-Angle Glaucoma

Japan
Alcon Research

Completed

A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma
Ono Pharmaceutical Co. Ltd

Completed

A 28 Day Study of ONO-9054 Ophthalmic Solution in Subjects With Ocular Hypertension (OHT) or Open-angle Glaucoma (OAG)

Ocular Hypertension | Open Angle-glaucoma

United States
Ophthalmic Consultants Centres, Canada
Alcon Research

Completed

A 12 Week Comparison of DuoTrav and Xalacom in Open-Angle Glaucoma (DVX)

Ocular Hypertension | Open-Angle Glaucoma

Canada
Vistakon Pharmaceuticals

Completed

A Comfort Survey of Open-angle Glaucoma or Ocular Hypertension Patients Treated With 2 Drugs

Ocular Hypertension | Open-angle Glaucoma

United States
Allergan

Terminated

A Study of Quantitative Assessments of Angle Width in Chinese Patients With Open-angle Glaucoma and/or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma

China
Alcon Research

Completed

Safety Study of DuoTrav APS in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma
Alcon Research

Completed

Fixed Combination Brinzolamide 1%/Timolol 0.5% Versus Brinzolamide 1% + Timolol 0.5% in Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma
Alcon Research

Terminated

Safety and Intraocular Pressure (IOP) Lowering Effect of AL-59412C

Ocular Hypertension | Open-angle Glaucoma
Mati Therapeutics Inc.
QLT Inc.

Completed

A Phase 2 Study of Punctal Placement of the Latanoprost Punctal Plug Delivery System (L-PPDS)

Ocular Hypertension | Open-Angle Glaucoma

United States
University of Zurich

Unknown

IOP Lowering Effect of PLT Versus SLT in Naiv OAG Patients

Ocular Hypertension | Open Angle Glaucoma,

Switzerland
Alcon Research

Terminated

Study of TRAVATAN in Subjects With Iris Pigmentation Changes

Ocular Hypertension | Open-Angle Glaucoma
Alcon Research

Completed

Travoprost 0.004%/Timolol 0.5% Versus Latanoprost 0.005%/Timolol in Chinese Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma

China
Santen Oy

Completed

Tafluprost-Timolol Preservative-free Fixed Dose Combination (FDC) Superiority Study Against Monotherapies

Ocular Hypertension | Open-angle Glaucoma

Finland
Alcon Research

Completed

Adjunctive Study of AL-37807 Ophthalmic Suspension

Ocular Hypertension | Open-Angle Glaucoma

United States
Alcon Research

Terminated

Phase 4 Study Comparing IOP Lowering in OAG or OH in Caucasian or Japanese Subjects C-02-32

Ocular Hypertension | Open-angle Glaucoma
Alcon Research

Completed

Adherence Assessment With Travalert Dosing Aid

Ocular Hypertension | Open-angle Glaucoma

Spain
Alcon Research

Terminated

Study of Travatan and Cosopt in Primary Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma

Portugal
Meir Medical Center

Withdrawn

The Effects of Cosopt® Vs Xalacom® on Ocular Hemodynamics and Intraocular Pressure (IOP) in Primary Open-angle Glaucoma (POAG) (Xal-Cos)

Ocular Hypertension | Open-Angle Glaucoma

Israel
Alcon Research

Completed

A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma

United States
Santen Inc.

Completed

Safety and Efficacy Study of DE-104 Ophthalmic Solution to Treat Open-angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma

United States
Santen Oy

Completed

Pharmacodynamics of Tafluprost 0.0015% Eye Drops: a Comparison Between the Preserved and Unpreserved Formulation

Ocular Hypertension | Open-Angle Glaucoma

Finland, Germany

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