Clinical Trials on Primary Gout and Hyperuricemia in South Africa

Total 3534 results

Pfizer

Completed

The Efficacy, Safety And Toleration Of CP-866,087 In Pre-Menopausal Women With Female Sexual Arousal Disorder.

Sexual Dysfunction, Physiological

Australia, Denmark, South Africa, Norway, Sweden
BioCryst Pharmaceuticals

Completed

Study to Evaluate the Urate-Lowering Activity and Safety of Oral BCX4208 Administered in Subjects With Gout

Gout

United States
MedImmune LLC

Completed

A Phase 1b/2a Randomized, Double-Blind, Placebo-controlled, Dose-escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of MEDI8897, a Monoclonal Antibody With an Extended Half-life Against Respiratory Syncytial Virus, in Healthy Preterm Infants (MEDI8897 1b)

Respiratory Syncytial Virus

United States, South Africa, Chile
International Maternal Pediatric Adolescent AIDS...
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Not yet recruiting

Safety and Immunogenicity of VPM1002 Vaccination or BCG Revaccination Against TB in Pre-Adolescents Living With and Without HIV in South Africa

HIV Infections | Tuberculosis

South Africa
Bill & Melinda Gates Medical Research Institute
Wellcome Trust

Completed

Safety and Immunogenicity of a Mycobacterium Tuberculosis Vaccine M72/AS01E in Participants With Well-controlled HIV (MESA-TB)

Human Immunodeficiency Virus

South Africa
Bristol-Myers Squibb

Completed

Pharmacokinetics of Atazanavir/Ritonavir in HIV-1 Infected Pregnant Women

HIV Infection

South Africa, Puerto Rico, United States
National Institute of Allergy and Infectious Diseases...
Microbicide Trials Network

Completed

Adherence and Acceptability to and Blood Levels of Tenofovir Gel and Tablets in HIV Uninfected Women

HIV Infections

United States, Uganda, South Africa
National Institute of Allergy and Infectious Diseases...
GlaxoSmithKline; Sanofi Pasteur, a Sanofi Company; HIV Vaccine Trials Network

Completed

Safety and Immunogenicity of Clade C ALVAC and gp120 HIV Vaccine (HVTN107)

HIV Infections

South Africa, Mozambique, Zimbabwe
Regeneron Pharmaceuticals

Completed

Study of the Safety and Effectiveness of Rilonacept for the Prevention of Gout Flares

Gout

United States
Bayer

Completed

REPEAT - Real-Life Perception of Efficacy, Attitude, Satisfaction and Safety of Levitra Therapy

Erectile Dysfunction

Poland, China, Croatia, France, Germany, Hungary, Indonesia, Korea, Republic of, Malaysia, Saudi Arabia, Singapore, South Africa, Spain, Sweden, Thailand
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Active, not recruiting

Evaluating the Pharmacokinetics, Safety, and Tolerability of Bedaquiline in Infants, Children, and Adolescents With Multidrug-Resistant Tuberculosis, Living With or Without HIV

HIV | Tuberculosis

Haiti, India, South Africa
Ardea Biosciences, Inc.

Completed

Lesinurad and Febuxostat Combination Extension Study in Gout

Gout

United States, Canada, Australia, New Zealand, Switzerland, Poland
Janssen Research & Development, LLC

Completed

A Study of Switching to RPV Plus Other ARVs in HIV-1-infected Children (Aged 2 to <12 Years) Who Are Virologically Suppressed

HIV

Italy, Thailand, Spain, Uganda, Portugal, South Africa
Vir Biotechnology, Inc.
National Institute of Allergy and Infectious Diseases (NIAID); HIV Vaccine...

Recruiting

To Investigate Safety, Reactogenicity and Immunogenicity of VIR-1388 Compared With Placebo in Participants Without HIV

HIV I Infection

United States, South Africa
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Not yet recruiting

Pausing Antiretroviral Treatment Under Structured Evaluation (PAUSE)

HIV-1-infection

Malawi, South Africa, Botswana
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Pharmacokinetics, Safety, and Tolerability of Doravirine (MK-1439) and Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate (MK-1439A) in HIV-1-Infected Children and Adolescents

HIV Infections

United States, South Africa, Thailand
Sanofi
Genzyme, a Sanofi Company

Completed

E3-Hormone Refractory Prostrate Cancer Taxotere Combination

Prostate Cancer | Metastatic | Hormone Refractory

Brazil, South Africa, Sweden, Germany, Hungary
Ardea Biosciences, Inc.

Completed

Lesinurad and Allopurinol Combination Extension Study in Gout

Gout

United States, South Africa, Spain, Belgium, Australia, Germany, Canada, New Zealand, Poland, Ukraine, Switzerland
HIV Vaccine Trials Network
National Institute of Allergy and Infectious Diseases (NIAID); Biofabri, S.L

Recruiting

Evaluating the Safety and Immunogenicity of MTBVAC in Adolescents and Adults Living With and Without HIV in South Africa (HVTN605A5421)

Tuberculosis | HIV I Infection

South Africa
National Institute of Allergy and Infectious Diseases...
Microbicide Trials Network

Completed

Safety and Effectiveness of TFV 1% Gel, TDF Tablets, and FTC/TDF Tablets in Preventing HIV in Women

HIV Infections

South Africa, Uganda, Zimbabwe
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Study of Effects of Tenofovir on Bone Health and Kidneys During Pregnancy and Breastfeeding

HIV Infections

Malawi, South Africa, Zimbabwe, Uganda
Allergan

Completed

Safety and Efficacy Study of Botulinum Toxin Type A for the Treatment of Neurogenic Overactive Bladder

Overactive Bladder

Portugal, South Africa, Netherlands, Canada, Singapore, Brazil, United States, Taiwan, Italy, United Kingdom, France, Spain
Astellas Pharma Inc
Medivation LLC, a wholly owned subsidiary of Pfizer Inc.

Completed

A Study to Assess the Safety of Continued Administration of MDV3100 in Subjects With Prostate Cancer Who Showed Benefit From Prior Exposure to MDV3100

Castration-Resistant Prostate Cancer (CRPC)

United States, Moldova, Republic of, South Africa
Tibotec Pharmaceuticals, Ireland
Tibotec Pharmaceutical Limited

Completed

A Safety Study to Evaluate the Antiviral Activity of Darunavir in Combination With Ritonavir in HIV 1 Infected Children

Human Immunodeficiency Virus 1

South Africa, Argentina, Brazil, India, Kenya
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Study of Oral and Long-Acting Injectable Cabotegravir and Rilpivirine in Virologically Suppressed Children Living With HIV-1, Two to Less Than 12 Years of Age

HIV-1-infection

United States, Brazil, South Africa, Uganda, Botswana, Thailand
Hoffmann-La Roche

Completed

A Study of Continued Treatment Among Participants Who Have Responded to Peginterferon Alfa-2a (Pegasys®) or Recombinant Interferon Alfa-2a (Roferon-A®) in Prior Clinical Studies

Renal Cell Carcinoma | Chronic Myelogenous Leukemia | Malignant Melanoma

Canada, India, Bulgaria, Russian Federation, Spain, South Africa, Slovakia
Janssen Vaccines & Prevention B.V.
National Institute of Allergy and Infectious Diseases (NIAID); Beth Israel... and other collaborators

Completed

Safety, Tolerability, and Immunogenicity Study of Homologous Ad26 Mosaic Vector Vaccine Regimens or Heterologous Ad26 Mosaic and MVA Mosaic Vector Vaccine Regimens With Glycoprotein 140 (gp140) for Human Immunodeficiency Virus (HIV) Prevention

Healthy

United States, South Africa, Thailand, Uganda, Rwanda
Microbicide Trials Network
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Observational Study of HIV Infected Women Previously Enrolled in Other Microbicide Trials

HIV Infections

Malawi, Zimbabwe, Uganda, South Africa, Zambia
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID); National Institute...

Completed

A Study of Dementia and Neurological Problems in HIV Infected Patients Who Are Participating in ACTG A5175

HIV Infections

South Africa, Brazil, Zimbabwe, India, Malawi
BioCryst Pharmaceuticals

Active, not recruiting

Open-label Berotralstat Access to HAE Patients Previously Enrolled in Berotralstat Studies (APeX-A)

Hereditary Angioedema | HAE

France, North Macedonia, Poland, Korea, Republic of, Slovakia, South Africa, Czechia
National Institute of Allergy and Infectious Diseases...
Sanofi; GlaxoSmithKline; Bill and Melinda Gates Foundation

Completed

Pivotal Phase 2b/3 ALVAC/Bivalent gp120/MF59 HIV Vaccine Prevention Safety and Efficacy Study in South Africa (HVTN702)

HIV Infections

South Africa
International Partnership for Microbicides, Inc.

Completed

A Safety Study of Dapivirine Vaginal Ring in Africa

HIV Infections

South Africa, Tanzania, Malawi, Kenya
Pfizer

Recruiting

A Study to Learn About the Vaccine RSVpreF In Pregnant Participants With HIV and Their Infants (MORISOT)

Respiratory Syncytial Virus

South Africa
PENTA Foundation
ViiV Healthcare; Hospital Universitario 12 de Octubre; Cromsource; PHPT Foundation

Recruiting

Safety and Pharmacokinetics Evaluation of Fostemsavir + (OBT) in HIV-1 Infected Children and Adolescents Who Are Failing Their cART and Have Dual- or Triple-class Antiretroviral Resistance

HIV Infections With Multi Drug Resistant Virus

United States, South Africa, Mexico, Spain
National Institute of Allergy and Infectious Diseases...
National Institute on Drug Abuse (NIDA); Eunice Kennedy Shriver National Institute... and other collaborators

Completed

BufferGel and PRO 2000/5: Vaginal Gels to Prevent HIV Infection in Women

HIV Infections

United States, Malawi, South Africa, Zambia, Zimbabwe
FHI 360
United States Agency for International Development (USAID); Jhpiego; Wits Reproductive... and other collaborators

Recruiting

The CATALYST Study

HIV Prevention

Kenya, Lesotho, South Africa, Uganda, Zimbabwe
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Intra-operative Infra-red Fluorescent Imaging in Thyroid and Parathyroid Surgery

Total Thyroidectomy | Bilateral Neck Exploration for Primary Hyperparathyroidism

United Kingdom
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

NNRTI vs PI Regimens for HIV Infected Women After They Have Taken Nevirapine to Prevent Mother-To-Child HIV Transmission (OCTANE)

HIV Infections

South Africa, Botswana, Kenya, Malawi, Uganda, Zambia, Zimbabwe
Jiangsu Atom Bioscience and Pharmaceutical Co.,...

Enrolling by invitation

Extension Study of ABP-671 in Participants With Gout

Gout

United States, Georgia, Australia, Guatemala, Taiwan
Boehringer Ingelheim

Completed

A Phase I Multiple Dose Pharmacokinetic Study of Nevirapine Extended Release (XR) in HIV-1 Infected Children.

HIV Infections

United States, Botswana, Germany, South Africa
Jiangsu Atom Bioscience and Pharmaceutical Co.,...

Recruiting

Phase 2b/3 Study to Assess ABP-671 a Novel URAT1 Inhibitor in Participants With Gout

Gout

United States, Georgia, Australia, Guatemala, Taiwan
Debiopharm International SA
Quintiles, Inc.

Completed

Study on Efficacy, Pharmacokinetics, and Safety of Two Subcutaneous Injections of Triptorelin Embonate 6 Month Formulation in Patients With Advanced Prostate Cancer

Prostate Cancer

South Africa
PENTA Foundation
Baylor College of Medicine; University Hospital Birmingham NHS Foundation Trust and other collaborators

Recruiting

DTG/3TC Fixed Dose Formulations for the Maintenance of Virological Suppression in Children With HIV Infection Aged 2 to <15 Years Old (D3 (Penta21))

HIV Infections

Spain, United Kingdom, Thailand, South Africa, Uganda
National Institute of Allergy and Infectious Diseases...

Completed

Comparison of Three Anti-HIV Regimens to Prevent Nevirapine Resistance in Women Who Take Nevirapine During Pregnancy

HIV Infections

Tanzania, Haiti, Malawi, South Africa, India, Uganda
Sheffield Teaching Hospitals NHS Foundation Trust
Fluoptics Ltd, Grenoble, France

Completed

Near Infrared Fluorescent Imaging in Thyroid and Parathyroid Surgery With the Fluobeam(TM) System of Fluoptics

Primary Hyperparathyroidism

United Kingdom
Medical Research Council
European Organisation for Research and Treatment of Cancer - EORTC

Completed

Early Chemotherapy Based on CA 125 Level Alone Compared With Delayed Chemotherapy in Treating Patients With Recurrent Ovarian Epithelial , Fallopian Tube, or Primary Peritoneal Cancer

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cavity Cancer

Spain, Belgium, France, Netherlands, Austria, United Kingdom, Italy, South Africa, Portugal, Ireland
Ardea Biosciences, Inc.

Completed

Allopurinol Combination Study (RDEA594-203)

Gout

Poland, United States, Spain, Canada, Ukraine, United Kingdom
International Partnership for Microbicides, Inc.

Completed

Trial to Assess the Continued Safety of and Adherence to a Vaginal Ring Containing Dapivirine in Women

Human Immunodeficiency Virus

Malawi, South Africa, Uganda, Zimbabwe
National Institute of Allergy and Infectious Diseases...

Completed

Acute HIV Infection Observational Study

HIV Infections

United States, Malawi, South Africa, Tanzania, Uganda
Helsingborgs Hospital
Lund University; Region Skåne - Skånevård SUND; Copenhagen Trial Unit, Center... and other collaborators

Completed

Targeted Hypothermia Versus Targeted Normothermia After Out-of-hospital Cardiac Arrest (TTM-2)

Out-of-hospital Cardiac Arrest

Norway, Sweden, Denmark, France, New Zealand, United Kingdom, Belgium, United States, Australia, Austria, Czechia, Germany, Italy, Switzerland

Clinical Trials on Primary Gout and Hyperuricemia in South Africa

Sponsors and Collaborators

Medical Conditions

Drug Interventions

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CROs in Liberia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

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